{"id":23303,"date":"2026-03-27T09:40:41","date_gmt":"2026-03-27T01:40:41","guid":{"rendered":"https:\/\/stemcell-malaysia.com\/?p=23303"},"modified":"2026-07-17T19:35:02","modified_gmt":"2026-07-17T11:35:02","slug":"stem-cells-and-exosome-therapy-could-deramiocel-change-the-future-of-duchenne-muscular-dystrophy","status":"publish","type":"post","link":"https:\/\/stemcell-malaysia.com\/zh\/stem-cells-and-exosome-therapy-could-deramiocel-change-the-future-of-duchenne-muscular-dystrophy\/","title":{"rendered":"\u5e72\u7ec6\u80de\u4e0e\u5916\u6ccc\u4f53\u7597\u6cd5\uff1aDeramiocel\u80fd\u5426\u6539\u53d8\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u7684\u672a\u6765\uff1f"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"23303\" class=\"elementor elementor-23303\" data-elementor-post-type=\"post\">\n\t\t\t\t        <section class=\"elementor-section elementor-top-section elementor-element elementor-element-28c64ee1 elementor-section-boxed elementor-section-height-default elementor-section-height-default pxl-row-scroll-none pxl-zoom-point-false pxl-section-overflow-visible pxl-section-fix-none pxl-bg-color-none pxl-section-overlay-none\" data-id=\"28c64ee1\" data-element_type=\"section\">\n\n                \n                <div class=\"elementor-container elementor-column-gap-default \">\n                <div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-391f28b5 pxl-column-none pxl-column-overflow-hidden-no\" data-id=\"391f28b5\" data-element_type=\"column\">\r\n        <div class=\"elementor-widget-wrap elementor-element-populated\">\r\n                     \r\n        \t\t<div class=\"elementor-element elementor-element-77c776d9 elementor-widget elementor-widget-text-editor\" data-id=\"77c776d9\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t\n<h1 style=\"text-align: center;\">\u5e72\u7ec6\u80de\u4e0e\u5916\u6ccc\u4f53\u7597\u6cd5\uff1aDeramiocel\u80fd\u5426\u6539\u53d8\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\u7684\u672a\u6765\uff1f<\/h1>\n\n<figure><img decoding=\"async\" class=\"aligncenter\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/03\/pexels-cottonbro-7578800-1024x683.jpg\" alt=\"\" \/><\/figure>\n\n<p class=\"wp-block-paragraph\" style=\"text-align: center;\"><em>Deramiocel\u662f\u4e00\u79cd\u6e90\u81ea\u5e72\u7ec6\u80de\u7684\u5916\u6ccc\u4f53\u7597\u6cd5\uff0c\u76ee\u524d\u6b63\u63a5\u53d7\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08Food and Drug Administration\uff0cFDA\uff09\u9488\u5bf9\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\uff08Duchenne Muscular Dystrophy\uff0cDMD\uff09\u7684\u5ba1\u67e5\u3002\u4ee5\u4e0b\u662f\u5176\u79d1\u5b66\u539f\u7406\u548c\u4e34\u5e8a\u7ed3\u679c\u7684\u610f\u4e49\u3002<\/em><\/p>\n\n<h2 class=\"wp-block-heading\" style=\"text-align: center;\"><br \/>\u5386\u7ecf\u591a\u5e74\u7814\u53d1\u7684\u7597\u6cd5<\/h2>\n\n<p class=\"wp-block-paragraph\" data-path-to-node=\"4\">\u5bf9\u4e8e\u60a3\u6709DMD\u7684\u5bb6\u5ead\u800c\u8a00\uff0c\u5bfb\u627e\u6709\u6548\u6cbb\u7597\u65b9\u6cd5\u7684\u9053\u8def\u6f2b\u957f\u4e14\u8270\u96be\u3002\u5982\u4eca\uff0c\u4e00\u79cd\u690d\u6839\u4e8e\u5e72\u7ec6\u80de\u79d1\u5b66\u7684\u7597\u6cd5\u53ef\u80fd\u6b63\u9010\u6e10\u6210\u4e3a\u73b0\u5b9e\u3002<\/p>\n<p data-path-to-node=\"5\">2026\u5e743\u6708\uff0cFDA\u6062\u590d\u4e86\u5bf9Deramiocel\u7684\u5ba1\u67e5\u2014\u2014\u8fd9\u662f\u4e00\u79cd\u7531Capricor Therapeutics\u5f00\u53d1\u7684\u57fa\u4e8e\u7ec6\u80de\u548c\u5916\u6ccc\u4f53\uff08Exosomes\uff09\u7684\u7597\u6cd5\u2014\u2014\u5e76\u8bbe\u5b9a\u4e862026\u5e748\u670822\u65e5\u4e3a\u76ee\u6807\u51b3\u7b56\u65e5\u671f\u3002\u5982\u679c\u83b7\u5f97\u6279\u51c6\uff0c\u8fd9\u5c06\u6210\u4e3a\u9996\u4e2a\u88ab\u8bc1\u660e\u80fd\u591f\u540c\u65f6\u51cf\u7f13DMD\u60a3\u8005\u808c\u8089\u548c\u5fc3\u810f\u529f\u80fd\u8870\u9000\u7684\u7597\u6cd5\u3002<\/p>\n\n<h2 class=\"wp-block-heading\" style=\"text-align: center;\"><br \/>\u4ec0\u4e48\u662f\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\u75c7\uff1f<\/h2>\n\n<figure>\n<p class=\"wp-block-paragraph\" data-path-to-node=\"7\">DMD\u662f\u4e00\u79cd\u7f55\u89c1\u7684\u9057\u4f20\u6027\u75be\u75c5\uff0c\u4f1a\u5bfc\u81f4\u4eba\u4f53\u808c\u8089\u8fdb\u884c\u6027\u5206\u89e3\u3002\u5b83\u5f71\u54cd\u7740\u7f8e\u56fd\u7ea615,000\u4eba\uff0c\u5176\u4e2d\u51e0\u4e4e\u5168\u4e3a\u7537\u5b69\u3002\u8be5\u75be\u75c5\u662f\u7531\u4e00\u79cd\u79f0\u4e3a\u6297\u808c\u840e\u7f29\u86cb\u767d\uff08Dystrophin\uff09\u7684\u7f3a\u5931\u5f15\u8d77\u7684\uff0c\u8fd9\u79cd\u86cb\u767d\u901a\u5e38\u8d77\u7740\u4fdd\u6301\u808c\u8089\u7ec6\u80de\u5b8c\u6574\u7684\u4f5c\u7528\u3002<\/p>\n<p data-path-to-node=\"8\">\u968f\u7740\u65f6\u95f4\u7684\u63a8\u79fb\uff0c\u808c\u8089\u4f1a\u9010\u6e10\u51cf\u5f31\u2014\u2014\u5305\u62ec\u5fc3\u810f\u3002\u5fc3\u529b\u8870\u7aed\u76ee\u524d\u662fDMD\u60a3\u8005\u6b7b\u4ea1\u7684\u4e3b\u8981\u539f\u56e0\uff0c\u5927\u591a\u6570\u60a3\u8005\u65e0\u6cd5\u6d3b\u8fc7\u4e8c\u5341\u591a\u5c81\u3002\u76ee\u524d\u5c1a\u65e0\u6cbb\u6108\u65b9\u6cd5\uff0c\u73b0\u6709\u7684\u6cbb\u7597\u65b9\u6848\u4e5f\u53ea\u80fd\u90e8\u5206\u7f13\u89e3\u8be5\u75be\u75c5\u3002<\/p>\n<img decoding=\"async\" class=\"aligncenter\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/03\/pexels-thirdman-7659869-1024x683.jpg\" alt=\"\" \/><\/figure>\n\n<h2 class=\"wp-block-heading\" style=\"text-align: center;\"><br \/>Deramiocel\u662f\u5982\u4f55\u53d1\u6325\u4f5c\u7528\u7684\uff1f<\/h2>\n\n<p class=\"wp-block-paragraph\" data-path-to-node=\"10\">\u8fd9\u6b63\u662f\u5e72\u7ec6\u80de\u79d1\u5b66\u53d1\u6325\u4f5c\u7528\u4e4b\u5904\u3002Deramiocel\u7531\u4e00\u79cd\u7279\u6b8a\u7c7b\u578b\u7684\u5fc3\u810f\u7956\u7ec6\u80de\uff08Cardiac Progenitor Cells\uff09\u5236\u6210\uff0c\u88ab\u79f0\u4e3a\u5fc3\u7403\u6765\u6e90\u7ec6\u80de\uff08Cardiosphere-Derived Cells\uff0cCDCs\uff09\u2014\u2014\u8fd9\u4e9b\u7ec6\u80de\u662f\u4ece\u4f9b\u4f53\u5fc3\u810f\u7ec4\u7ec7\u4e2d\u63d0\u53d6\u7684\u3002\u8fd9\u4e9b\u7ec6\u80de\u7684\u884c\u4e3a\u4e0e\u5e72\u7ec6\u80de\u76f8\u4f3c\uff1a\u5b83\u4eec\u80fd\u591f\u5f52\u5de2\u81f3\u53d7\u635f\u533a\u57df\uff0c\u5e76\u5e2e\u52a9\u5468\u56f4\u7ec4\u7ec7\u8fdb\u884c\u81ea\u6211\u4fee\u590d\u3002<\/p>\n<p data-path-to-node=\"11\">\u5b83\u4eec\u4e3b\u8981\u901a\u8fc7\u91ca\u653e\u79f0\u4e3a\u5916\u6ccc\u4f53\u7684\u5fae\u5c0f\u9897\u7c92\u6765\u5b9e\u73b0\u8fd9\u4e00\u70b9\u3002\u53ef\u4ee5\u5c06\u5916\u6ccc\u4f53\u89c6\u4e3a\u751f\u7269\u5b66\u4e0a\u7684\u77ed\u4fe1\u2014\u2014\u5b83\u4eec\u5411\u514d\u75ab\u7ec6\u80de\u4f20\u9012\u6307\u4ee4\uff0c\u544a\u8bc9\u5b83\u4eec\u4ece\u5f15\u53d1\u708e\u75c7\u8f6c\u53d8\u4e3a\u534f\u52a9\u6108\u5408\u3002\u8fd9\u6b63\u662fDeramiocel\u533a\u522b\u4e8e\u4f20\u7edf\u836f\u7269\u7597\u6cd5\u7684\u5730\u65b9\u3002\u5b83\u5728\u7ec6\u80de\u5c42\u9762\u4e0a\u53d1\u6325\u4f5c\u7528\uff0c\u91cd\u65b0\u7f16\u7a0b\u4eba\u4f53\u5bf9\u635f\u4f24\u7684\u53cd\u5e94\u65b9\u5f0f\uff0c\u800c\u4e0d\u4ec5\u4ec5\u662f\u63a7\u5236\u75c7\u72b6\u3002<\/p>\n\n<h2 class=\"wp-block-heading\" style=\"text-align: center;\"><br \/>\u4e34\u5e8a\u8bd5\u9a8c\u663e\u793a\u4e86\u4ec0\u4e48\uff1f<\/h2>\n\n<p class=\"wp-block-paragraph\" data-path-to-node=\"13\">\u652f\u6301\u6b64\u6b21FDA\u7533\u8bf7\u7684\u4e34\u5e8a\u8bc1\u636e\u6765\u81eaHOPE-3\u8bd5\u9a8c\u2014\u2014\u8fd9\u662f\u4e00\u9879\u4e25\u8c28\u7684III\u671f\u7814\u7a76\uff08Phase III Study\uff09\uff0c\u6db5\u76d6\u4e86106\u540d\u5e73\u5747\u5e74\u9f84\u7ea6\u4e3a15\u5c81\u7684DMD\u60a3\u8005\u3002\u4e00\u534a\u7684\u60a3\u8005\u572812\u4e2a\u6708\u5185\u901a\u8fc7\u56db\u6b21\u9759\u8109\u8f93\u6ce8\u63a5\u53d7\u4e86Deramiocel\u6cbb\u7597\uff1b\u53e6\u4e00\u534a\u5219\u63a5\u53d7\u4e86\u5b89\u6170\u5242\u3002<\/p>\n<p data-path-to-node=\"14\">\u7ed3\u679c\u663e\u8457\u3002\u63a5\u53d7Deramiocel\u6cbb\u7597\u7684\u60a3\u8005\u51fa\u73b0\u4e86\uff1a<\/p>\n<ol start=\"1\" data-path-to-node=\"15\">\n<li>\n<p data-path-to-node=\"15,0,0\">\u4e0a\u80a2\u529f\u80fd\u8870\u9000\u901f\u5ea6\u51cf\u7f13\u4e8654%\u2014\u2014\u8fd9\u610f\u5473\u7740\u4ed6\u4eec\u7684\u624b\u81c2\u548c\u624b\u90e8\u80fd\u66f4\u957f\u65f6\u95f4\u5730\u4fdd\u6301\u529b\u91cf<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"15,1,0\">\u5fc3\u810f\u6cf5\u8840\u529f\u80fd\uff08\u5de6\u5fc3\u5ba4\u5c04\u8840\u5206\u6570\uff0cLeft Ventricular Ejection Fraction\uff09\u8870\u9000\u901f\u5ea6\u51cf\u7f13\u4e8691%\u2014\u2014\u8fd9\u662f\u5fc3\u810f\u5065\u5eb7\u7684\u4e00\u4e2a\u5173\u952e\u6307\u6807<\/p>\n<\/li>\n<\/ol>\n<p data-path-to-node=\"16\">\u6240\u6709\u9884\u5148\u6307\u5b9a\u7684\u8bd5\u9a8c\u7ec8\u70b9\u5747\u5df2\u8fbe\u5230\u3002\u8fd9\u662f\u5728\u5bf9\u7167\u4e34\u5e8a\u7814\u7a76\u4e2d\uff0c\u9996\u6b21\u6709\u5355\u4e00\u7597\u6cd5\u8bc1\u660e\u5bf9DMD\u9aa8\u9abc\u808c\u548c\u5fc3\u810f\u529f\u80fd\u5747\u4ea7\u751f\u53ef\u6d4b\u91cf\u7684\u76ca\u5904\u3002<\/p>\n\n<figure><img decoding=\"async\" class=\"aligncenter\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/03\/pexels-rdne-6129444-1024x683.jpg\" alt=\"\" \/><\/figure>\n\n<h2 class=\"wp-block-heading\" style=\"text-align: center;\"><br \/>\u5b83\u7684\u76d1\u7ba1\u73b0\u72b6\u5982\u4f55\uff1f<\/h2>\n\n<p class=\"wp-block-paragraph\" data-path-to-node=\"18\">FDA\u6700\u521d\u4e8e2025\u5e747\u6708\u5411Capricor\u53d1\u51fa\u4e86\u4e00\u4efd\u5b8c\u6574\u56de\u5e94\u51fd\uff08Complete Response Letter\uff09\u2014\u2014\u8fd9\u662f\u4e00\u4e2a\u6807\u51c6\u6b65\u9aa4\uff0c\u8868\u660e\u5728\u505a\u51fa\u51b3\u5b9a\u4e4b\u524d\u9700\u8981\u66f4\u591a\u4fe1\u606f\u3002\u5728Capricor\u63d0\u4ea4\u4e86HOPE-3\u6570\u636e\u540e\uff0cFDA\u64a4\u56de\u4e86\u8be5\u51fd\u4ef6\u5e76\u6062\u590d\u4e86\u5ba1\u67e5\uff0c\u622a\u81f32026\u5e743\u6708\u672a\u53d1\u73b0\u4efb\u4f55\u60ac\u800c\u672a\u51b3\u7684\u95ee\u9898\u3002<\/p>\n<p data-path-to-node=\"19\">Deramiocel\u83b7\u5f97\u4e86\u591a\u9879\u76d1\u7ba1\u8ba4\u5b9a\uff0c\u8fd9\u53cd\u6620\u4e86\u536b\u751f\u5f53\u5c40\u5bf9\u5176\u6f5c\u529b\u7684\u91cd\u89c6\u7a0b\u5ea6\uff1a<\/p>\n<ol start=\"1\" data-path-to-node=\"20\">\n<li>\n<p data-path-to-node=\"20,0,0\">\u5b64\u513f\u836f\u8d44\u683c\u8ba4\u5b9a\uff08Orphan Drug Designation\uff0c\u7531FDA\u548c\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40\u5373European Medicines Agency, EMA\u9881\u53d1\uff09\u2014\u2014\u9488\u5bf9\u7f55\u89c1\u75be\u75c5\u72b6\u6001<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"20,1,0\">RMAT\u8ba4\u5b9a\uff08RMAT Designation\uff0cFDA\uff09\u2014\u2014\u9488\u5bf9\u518d\u751f\u533b\u5b66\uff08\u5305\u62ec\u5e72\u7ec6\u80de\u7597\u6cd5\uff09\u7684\u52a0\u901f\u5ba1\u6279\u901a\u9053<\/p>\n<\/li>\n<li>\n<p data-path-to-node=\"20,2,0\">\u7f55\u89c1\u513f\u79d1\u75be\u75c5\u8ba4\u5b9a\uff08Rare Pediatric Disease 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