{"id":25282,"date":"2026-05-20T08:42:32","date_gmt":"2026-05-20T00:42:32","guid":{"rendered":"https:\/\/stemcell-malaysia.com\/?page_id=25282"},"modified":"2026-05-20T08:42:34","modified_gmt":"2026-05-20T00:42:34","slug":"psoriasis","status":"publish","type":"page","link":"https:\/\/stemcell-malaysia.com\/zh\/conditions\/psoriasis\/","title":{"rendered":"\u94f6\u5c51\u75c5\u5e72\u7ec6\u80de\u6cbb\u7597\uff5c\u4e0d\u52a0\u5927\u751f\u7269\u5236\u5242\u4e5f\u80fd\u5e73\u606f\u514d\u75ab\u98ce\u66b4\u5417"},"content":{"rendered":"\n<h1 class=\"wp-block-heading has-text-align-center\">\u94f6\u5c51\u75c5\u5e72\u7ec6\u80de\u6cbb\u7597\uff5c\u4e0d\u52a0\u5927\u751f\u7269\u5236\u5242\u4e5f\u80fd\u5e73\u606f\u514d\u75ab\u98ce\u66b4\u5417<\/h1>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"436\" 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style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u76ee\u5f55<\/mark><\/h2>\n\n\n<div class=\"wp-block-aioseo-table-of-contents\"><ol><li><a class=\"aioseo-toc-item\" href=\"#aioseo-why-psoriasis-doesnt-stay-in-remission-8\">\u94f6\u5c51\u75c5\u4e3a\u4ec0\u4e48\u7f13\u89e3\u540e\u53c8\u4f1a\u5377\u571f\u91cd\u6765<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u5f53\u524d\u7684\u94f6\u5c51\u75c5\u6cbb\u7597\u5728\u54ea\u4e9b\u573a\u666f\u4e0b\u8d70\u5230\u5c3d\u5934-19\">\u5f53\u524d\u7684\u94f6\u5c51\u75c5\u6cbb\u7597\u5728\u54ea\u4e9b\u573a\u666f\u4e0b\u8d70\u5230\u5c3d\u5934<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-what-clinical-trials-show-for-psoriasis-stem-cell-treatment-31\">\u94f6\u5c51\u75c5\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u4e34\u5e8a\u6570\u636e\u600e\u4e48\u8bf4<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-how-stem-cell-therapy-engages-the-psoriasis-immune-loop-46\">\u5e72\u7ec6\u80de\u6cbb\u7597\u5982\u4f55\u4f5c\u7528\u4e8e\u94f6\u5c51\u75c5\u7684\u514d\u75ab\u73af\u8def<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u8c01\u9002\u5408\u8c01\u4e0d\u9002\u5408\u94f6\u5c51\u75c5\u5e72\u7ec6\u80de\u6cbb\u7597-61\">\u8c01\u9002\u5408\u3001\u8c01\u4e0d\u9002\u5408\u94f6\u5c51\u75c5\u5e72\u7ec6\u80de\u6cbb\u7597<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u4e00\u4f4d\u94f6\u5c51\u75c5\u60a3\u8005\u63a5\u53d7\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u771f\u5b9e\u7ecf\u8fc7-72\">\u4e00\u4f4d\u94f6\u5c51\u75c5\u60a3\u8005\u63a5\u53d7\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u771f\u5b9e\u7ecf\u8fc7<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u94f6\u5c51\u75c5\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u8bda\u5b9e\u98ce\u9669\u4e0e\u5c40\u9650-93\">\u94f6\u5c51\u75c5\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u8bda\u5b9e\u98ce\u9669\u4e0e\u5c40\u9650<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-faq-about-psoriasis-stem-cell-therapy-104\">\u94f6\u5c51\u75c5\u5e72\u7ec6\u80de\u6cbb\u7597\u5e38\u89c1\u95ee\u9898<\/a><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-next-step-131\">\u4e0b\u4e00\u6b65<\/a><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-references-135\">\u53c2\u8003\u6587\u732e<\/a><\/li><\/ol><\/div>\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-why-psoriasis-doesnt-stay-in-remission-8\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u94f6\u5c51\u75c5\u4e3a\u4ec0\u4e48\u7f13\u89e3\u540e\u53c8\u4f1a\u5377\u571f\u91cd\u6765<\/mark><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-the-immune-misfire-that-drives-psoriasis-plaques-9\">\u94f6\u5c51\u75c5\u80cc\u540e\u7684\u514d\u75ab\u7cfb\u7edf\u8bef\u5224<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u94f6\u5c51\u75c5\u7684\u75c7\u72b6\u51fa\u73b0\u5728\u76ae\u80a4\u4e0a\uff0c\u4f46\u672c\u8d28\u662f\u514d\u75ab\u7cfb\u7edf\u7684\u529f\u80fd\u7d0a\u4e71\u3002<\/p>\n\n\n\n<p 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class=\"wp-block-paragraph\">\u5f88\u591a\u60a3\u8005\u5e76\u4e0d\u662f\u67d0\u4e00\u5929\u7a81\u7136\u6025\u5267\u6076\u5316\uff0c\u800c\u662f\u6162\u6162&#8221;\u7d2f\u4e86&#8221;\u3002\u7d2f\u4e8e\u53cd\u590d\u6362\u836f\uff0c\u7d2f\u4e8e\u6bcf\u6b21\u90fd\u8981\u7b4912\u5468\u770b\u65b0\u836f\u7ba1\u4e0d\u7ba1\u7528\uff0c\u7d2f\u4e8e\u6301\u7eed\u7684\u76d1\u6d4b\u548c\u4e0d\u83f2\u7684\u8d39\u7528\u2014\u2014\u5c24\u5176\u5728\u4e2d\u56fd\uff0c\u4e2d\u56fd\u94f6\u5c51\u75c5\u836f\u7269\u5e02\u573a\u75312018\u5e74\u76846.04\u4ebf\u7f8e\u5143\u5feb\u901f\u589e\u957f\u81f32022\u5e74\u768414.36\u4ebf\u7f8e\u5143\uff0c\u80cc\u540e\u662f\u60a3\u8005\u771f\u5b9e\u7684\u7ecf\u6d4e\u8d1f\u62c5\u3002\u8fd9\u65f6\u5019\uff0c&#8221;\u6709\u6ca1\u6709\u4e00\u79cd\u6839\u672c\u4e0d\u4e00\u6837\u7684\u673a\u5236&#8221;\u2014\u2014\u8fd9\u4e2a\u95ee\u9898\u5c31\u51fa\u73b0\u4e86\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-what-clinical-trials-show-for-psoriasis-stem-cell-treatment-31\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u94f6\u5c51\u75c5\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u4e34\u5e8a\u6570\u636e\u600e\u4e48\u8bf4<\/mark><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"800\" height=\"733\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-1-7.webp\" alt=\"Cheng 2022 Phase 1\/2a\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u94f6\u5c51\u75c5\u60a3\u8005\u63a5\u53d7\u8110\u5e26\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u540ePASI\u6539\u5584\u7387\u67f1\u72b6\u56fe\n\" class=\"wp-image-25285\" style=\"aspect-ratio:1.0974104970455336;width:428px;height:auto\" srcset=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-1-7.webp 800w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-1-7-300x275.webp 300w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-1-7-768x704.webp 768w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-1-7-775x710.webp 775w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption class=\"wp-element-caption\">Cheng 2022 phase 1\/2a\u8bd5\u9a8c\u4e2d\uff0c17\u4f8b\u94f6\u5c51\u75c5\u60a3\u800547.1%(8\u4f8b)\u5728\u8110\u5e26MSC\u8f93\u6ce8\u540ePASI\u6539\u5584\u8fbe40%\u4ee5\u4e0a\u3002\u7537\u5973\u5e94\u7b54\u7387\u5448\u73b0\u663e\u8457\u5dee\u5f02\u3002<\/figcaption><\/figure>\n<\/div>\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-key-studies-on-allogeneic-umbilical-cord-mscs-in-psoriasis-32\">\u540c\u79cd\u5f02\u4f53\u8110\u5e26MSC\u7684\u5173\u952e\u7814\u7a76<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u94f6\u5c51\u75c5\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u4e34\u5e8a\u8bc1\u636e\uff0c\u6bd4\u6210\u719f\u7684\u751f\u7269\u5236\u5242\u5e74\u8f7b\uff0c\u4f46\u6bd4\u8bb8\u591a\u5ba3\u4f20\u6587\u7ae0\u6240\u6697\u793a\u7684\u8981\u5177\u4f53\uff0c\u4e5f\u6bd4\u6700\u70ed\u60c5\u7684\u5ba3\u79f0\u8981\u8c28\u614e\u5f97\u591a\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6700\u76f4\u63a5\u76f8\u5173\u7684\u7814\u7a76\u662fCheng\u7b49\u4eba2022\u5e74\u53d1\u8868\u4e8eSignal Transduction and Targeted Therapy\u7684Phase 1\/2a\u5355\u81c2\u8bd5\u9a8c\u3002\u8be5\u8bd5\u9a8c\u5165\u7ec417\u4f8b\u94f6\u5c51\u75c5\u60a3\u8005\uff0c\u63a5\u53d7\u4eba\u8110\u5e26\u95f4\u5145\u8d28\u5e72\u7ec6\u80de(MSC)\u9759\u8109\u8f93\u6ce8\uff0c\u5e76\u968f\u8bbf6\u4e2a\u6708\u8bc4\u4f30\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u3002\u4e3b\u8981\u8bc4\u4f30\u6307\u6807\u5305\u62ecPASI(\u94f6\u5c51\u75c5\u4e25\u91cd\u7a0b\u5ea6\u56fd\u9645\u6807\u51c6\u8bc4\u5206)\u3001PGA(\u533b\u751f\u6574\u4f53\u8bc4\u4f30)\u3001\u5b9e\u9a8c\u5ba4\u6307\u6807\u7b49\u3002 <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7ed3\u679c\u88ab\u8c28\u614e\u5730\u62a5\u544a\u300217\u4f8b\u60a3\u8005\u4e2d8\u4f8b(47.1%)PASI\u8bc4\u5206\u6539\u5584\u8fbe\u523040%\u4ee5\u4e0a\uff0c3\u4f8b(17.6%)\u6309PGA\u8fbe\u5230&#8221;\u65e0\u76ae\u635f\u6216\u6700\u5c0f\u6b8b\u7559\u75be\u75c5&#8221;\u3002\u4e9a\u7ec4\u5206\u6790\u663e\u793a\u4e00\u4e2a\u91cd\u8981\u73b0\u8c61\uff1a\u7537\u6027\u5e94\u7b54\u7387\u4e3a25%(2\/8)\uff0c\u5973\u6027\u5e94\u7b54\u7387\u4e3a66.7%(6\/9)\u3002\u5728\u6cbb\u7597\u53ca6\u4e2a\u6708\u968f\u8bbf\u671f\u95f4\u672a\u89c2\u5bdf\u5230\u660e\u663e\u4e0d\u826f\u53cd\u5e94\u3002 <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u53e6\u4e00\u9879\u7814\u7a76\u662fYao\u7b49\u4eba2021\u5e74\u53d1\u8868\u4e8eAnnals of Translational Medicine\u7684\u5355\u81c2\u8bd5\u9a8c\uff0c\u5bf97\u4f8b\u4e2d\u91cd\u5ea6\u94f6\u5c51\u75c5\u60a3\u8005\u4f7f\u7528\u8102\u80aa\u6765\u6e90MSC\u9759\u8109\u8f93\u6ce8\u3002\u8bc4\u4f30PASI\u3001\u4f53\u8868\u9762\u79ef(BSA)\u3001VAS\u3001\u76ae\u80a4\u75c5\u751f\u6d3b\u8d28\u91cf\u6307\u6570(DLQI)\u540e\uff0c\u7ed3\u8bba\u662f\u8102\u80aa\u6765\u6e90MSC\u7684\u9759\u8109\u8f93\u6ce8\u662f\u5b89\u5168\u7684\uff0c\u53ef\u80fd\u6210\u4e3a\u94f6\u5c51\u75c5\u60a3\u8005\u7684\u4e00\u79cd\u6cbb\u7597\u9009\u62e9\uff0c\u4f5c\u8005\u540c\u65f6\u547c\u5401\u9700\u8981\u66f4\u5927\u6837\u672c\u548c\u5bf9\u7167\u7ec4\u7684\u7814\u7a76\u3002 <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Bajouri\u7b49\u4eba2023\u5e74\u53d1\u8868\u4e8eCell Journal\u7684Phase I\u8bd5\u9a8c\uff0c\u91c7\u7528\u4e86\u4e0d\u540c\u7684\u7ed9\u836f\u65b9\u5f0f\u2014\u2014\u5c06\u540c\u79cd\u5f02\u4f53\u8102\u80aa\u6765\u6e90MSC\u76f4\u63a5\u76ae\u4e0b\u6ce8\u5c04\u52305\u4f8b\u60a3\u8005\u7684\u94f6\u5c51\u75c5\u76ae\u635f\u4e2d\uff0c\u4e3b\u8981\u7ed3\u8bba\u662f\u5b89\u5168\u3002<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-\u8fd9\u4e9b\u6570\u5b57\u5bf9\u94f6\u5c51\u75c5\u60a3\u8005\u6765\u8bf4\u7a76\u7adf\u610f\u5473\u7740\u4ec0\u4e48-41\">\u8fd9\u4e9b\u6570\u5b57\u5bf9\u94f6\u5c51\u75c5\u60a3\u8005\u6765\u8bf4\u7a76\u7adf\u610f\u5473\u7740\u4ec0\u4e48<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u6211\u4eec\u60f3\u628a\u8fd9\u4e9b\u6570\u5b57\u7ffb\u8bd1\u6210\u4f60\u80fd\u7528\u7684\u4fe1\u606f\uff0c\u56e0\u4e3a\u53ea\u6311\u6f02\u4eae\u6570\u5b57\u7684\u603b\u7ed3\u5bf9\u60a3\u8005\u662f\u4e0d\u8d1f\u8d23\u4efb\u7684\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">PASI 40%\u6539\u5584\u662f\u4e00\u4e2a\u6709\u4e34\u5e8a\u610f\u4e49\u7684\u53d8\u5316\u2014\u2014\u5927\u81f4\u76f8\u5f53\u4e8e\u4ece&#8221;\u4e2d\u91cd\u5ea6\u3001\u76ae\u635f\u5e7f\u6cdb&#8221;\u53d8\u4e3a&#8221;\u76ae\u635f\u9762\u79ef\u7f29\u5c0f\u3001\u708e\u75c7\u5e73\u7a33&#8221;\u3002\u4f46\u5b83\u5e76\u4e0d\u662f\u751f\u7269\u5236\u5242\u4e34\u5e8a\u8bd5\u9a8c\u91cc\u5e38\u7528\u7684\u76ee\u6807PASI 75(75%\u6539\u5584)\uff0c\u66f4\u4e0d\u662fPASI 90\u6216PASI 100\u3002\u5728Cheng\u7684\u7814\u7a76\u4e2d\uff0c3\u540d\u60a3\u8005\u8fbe\u5230\u4e86PGA\u51e0\u4e4e\u65e0\u76ae\u635f\u7684\u72b6\u6001\u2014\u2014\u8fd9\u662f\u663e\u8457\u5e94\u7b54\uff1b\u4f46\u5927\u591a\u6570\u5e94\u7b54\u8005\u53ea\u662f\u90e8\u5206\u6539\u5584\uff0c\u800c\u4e0d\u662f\u5b8c\u5168\u6e05\u9664\u76ae\u80a4\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7537\u5973\u5e94\u7b54\u7387\u7684\u5dee\u5f02\u503c\u5f97\u4e25\u8083\u5bf9\u5f85\u3002\u5973\u602766.7%\u3001\u7537\u602725%\u7684\u5dee\u5f02\uff0c\u5176\u539f\u56e0\u76ee\u524d\u5e76\u672a\u5b8c\u5168\u660e\u4e86\u2014\u2014\u53ef\u80fd\u4e0e\u6fc0\u7d20\u5bf9\u514d\u75ab\u8c03\u8282\u7684\u5f71\u54cd\u3001\u57fa\u7ebf\u75be\u75c5\u7279\u70b9\u3001\u5176\u4ed6\u5c1a\u672a\u8bc6\u522b\u7684\u56e0\u7d20\u6709\u5173\u3002\u5b9e\u9645\u610f\u4e49\u5728\u4e8e\uff1a\u76ee\u524d\u7684\u6570\u636e\u4e0b\uff0c\u6211\u4eec\u65e0\u6cd5\u5bf9\u7537\u6027\u60a3\u8005\u548c\u5973\u6027\u60a3\u8005\u7ed9\u51fa\u540c\u6837\u7684\u9884\u671f\u3002\u6211\u4eec\u4f1a\u5728\u6cbb\u7597\u524d\u5982\u5b9e\u544a\u77e5\u6bcf\u4e00\u4f4d\u8bc4\u4f30\u8005\uff0c\u5c24\u5176\u662f\u7537\u6027\u60a3\u8005\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u540c\u6837\u91cd\u8981\u7684\u662f\u6570\u636e&#8221;\u8fd8\u6ca1\u544a\u8bc9\u6211\u4eec\u4ec0\u4e48&#8221;\u3002\u76ee\u524d\u6ca1\u6709\u5927\u89c4\u6a21\u3001\u968f\u673a\u5bf9\u7167\u3001\u957f\u671f\u968f\u8bbf\u7684III\u671f\u8bd5\u9a8c\u6765\u8bc1\u660e\u5e94\u7b54\u80fd\u7ef4\u6301\u52302\u5e74\u30013\u5e74\u30015\u5e74\u3002\u662f\u5426\u9700\u8981\u518d\u6b21\u8f93\u6ce8\u3001\u95f4\u9694\u591a\u4e45\u6700\u4f18\u2014\u2014\u8fd9\u4e9b\u95ee\u9898\u90fd\u8fd8\u6ca1\u6709\u5b9a\u8bba\u3002\u7814\u7a76\u5728\u524d\u8fdb\uff0c\u4f46\u5168\u8c8c\u8fd8\u6ca1\u62fc\u5b8c\u3002\u8fd9\u4e00\u70b9\u5fc5\u987b\u544a\u8bc9\u4f60\uff0c\u518d\u8ba9\u4f60\u51b3\u5b9a\u3002ch.<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-how-stem-cell-therapy-engages-the-psoriasis-immune-loop-46\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u5e72\u7ec6\u80de\u6cbb\u7597\u5982\u4f55\u4f5c\u7528\u4e8e\u94f6\u5c51\u75c5\u7684\u514d\u75ab\u73af\u8def<\/mark><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"800\" height=\"431\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-2-7.webp\" alt=\"\u94f6\u5c51\u75c5\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u4e09\u5927\u4f5c\u7528\u673a\u5236\u56fe\u89e3\uff1aTh17\u7ec6\u80de\u6291\u5236\u3001\u8c03\u8282\u6027T\u7ec6\u80de\u6269\u589e\u3001\u708e\u75c7\u6027\u7ec6\u80de\u56e0\u5b50\u51cf\u5c11\" class=\"wp-image-25286\" style=\"aspect-ratio:1.9231003502360287;width:639px;height:auto\" srcset=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-2-7.webp 800w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-2-7-300x162.webp 300w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-2-7-768x414.webp 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption class=\"wp-element-caption\">\u540c\u79cd\u5f02\u4f53\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u901a\u8fc7\u4e09\u6761\u4e92\u8865\u7684\u514d\u75ab\u8c03\u8282\u901a\u8def\u4f5c\u7528\u4e8e\u94f6\u5c51\u75c5\u2014\u2014\u76ee\u6807\u4e0d\u662f\u4e0b\u6e38\u7684\u708e\u75c7\u4fe1\u53f7\uff0c\u800c\u662f\u4e0a\u6e38\u7684\u514d\u75ab\u7ec6\u80de\u672c\u8eab\u3002<\/figcaption><\/figure>\n<\/div>\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-three-mechanisms-behind-psoriasis-stem-cell-therapy-47\">\u94f6\u5c51\u75c5\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u4e09\u5927\u673a\u5236<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u95f4\u5145\u8d28\u5e72\u7ec6\u80de(MSC)\u5bf9\u94f6\u5c51\u75c5\u7684\u4f5c\u7528\u65b9\u5f0f\uff0c\u4e0e\u751f\u7269\u5236\u5242\u5b8c\u5168\u4e0d\u540c\u3002\u751f\u7269\u5236\u5242\u662f&#8221;\u9010\u4e2a\u963b\u65ad\u708e\u75c7\u4fe1\u53f7&#8221;\uff0c\u800cMSC\u662f&#8221;\u548c\u53d1\u51fa\u8fd9\u4e9b\u4fe1\u53f7\u7684\u514d\u75ab\u7ec6\u80de\u5bf9\u8bdd&#8221;\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7b2c\u4e00\u4e2a\u673a\u5236\u662f\u76f4\u63a5\u6291\u5236\u81f4\u75c5\u514d\u75ab\u7ec6\u80de\u30022022\u5e74Cell and Tissue 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aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-next-step-131\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u4e0b\u4e00\u6b65<\/mark><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u8bfb\u5230\u8fd9\u91cc\u7684\u4f60\uff0c\u591a\u534a\u5df2\u7ecf\u8d70\u8fc7\u51e0\u8f6e\u6cbb\u7597\uff0c\u6b63\u8ba4\u771f\u5730\u60f3\u641e\u6e05\u695a\u5e72\u7ec6\u80de\u6cbb\u7597\u5bf9\u81ea\u5df1\u8fd9\u5177\u4f53\u4e00\u4f8b\u5230\u5e95\u6709\u6ca1\u6709\u610f\u4e49\u3002<\/p>\n\n\n\n<p 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class=\"has-inline-color\">\u53c2\u8003\u6587\u732e<\/mark><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Cheng L, Wang S, Peng C, Zou X, Yang C, Mei H, et al. Human umbilical cord mesenchymal stem cells for psoriasis: a phase 1\/2a, single-arm study. Signal Transduction and Targeted Therapy. 2022;7:263. <a href=\"https:\/\/doi.org\/10.1038\/s41392-022-01059-y\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1038\/s41392-022-01059-y<\/a><\/li>\n\n\n\n<li>Yao D, Ye S, He Z, Huang Y, Deng J, Wen Z, et al. Adipose-derived mesenchymal stem cells (AD-MSCs) in the treatment for psoriasis: results of a single-arm pilot trial. Annals of Translational Medicine. 2021;9(20):1653. <a href=\"https:\/\/doi.org\/10.21037\/atm-21-5028\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.21037\/atm-21-5028<\/a><\/li>\n\n\n\n<li>De Jesus MM, Santiago JS, Trinidad CV, See ME, Semon KR, Fernandez MO Jr, Chung FS. Stem cell therapy as a potential treatment option for psoriasis. Anais Brasileiros de Dermatologia. 2022;97(4):408\u2013424. <a href=\"https:\/\/doi.org\/10.1016\/j.abd.2021.09.011\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1016\/j.abd.2021.09.011<\/a><\/li>\n\n\n\n<li>Chen H, Niu JW, Ning HM, Pan X, Li XB, Li Y, et al. Mesenchymal stem cells alleviate moderate-to-severe psoriasis by reducing the production of type I interferon (IFN-I) by plasmacytoid dendritic cells (pDCs). Stem Cells International. 2019;2019:6961052. <a href=\"https:\/\/doi.org\/10.1155\/2019\/6961052\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1155\/2019\/6961052<\/a><\/li>\n\n\n\n<li>Chen Z, Wang H, Xia Y, Yan F, Lu Y. Human umbilical cord-derived mesenchymal stem cells ameliorate psoriasis-like dermatitis by suppressing IL-17-producing \u03b3\u03b4 T cells. Cell and Tissue Research. 2022;388(3):549\u2013563. <a href=\"https:\/\/doi.org\/10.1007\/s00441-022-03616-x\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1007\/s00441-022-03616-x<\/a><\/li>\n\n\n\n<li>Bertolini M, Bevilacqua J, Caruso M, et al. Mesenchymal stem cells for the treatment of psoriasis: a comprehensive review. Clinical and Experimental Rheumatology. 2020;38(5):964\u2013974. <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/32386432\/\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32386432\/<\/a><\/li>\n\n\n\n<li>GBD 2021 Diseases and Injuries Collaborators. Global burden of psoriasis from 1990 to 2021 and potential factors: a systematic analysis. Journal of Investigative Dermatology. 2025. <a href=\"https:\/\/doi.org\/10.1016\/j.jid.2025.05.024\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1016\/j.jid.2025.05.024<\/a><\/li>\n\n\n\n<li>Parisi R, Iskandar IYK, Kontopantelis E, Augustin M, Griffiths CEM, Ashcroft DM. Global epidemiology of psoriasis: a systematic review of incidence and prevalence. Journal of Investigative Dermatology. 2020;140(3):568\u2013576. <a href=\"https:\/\/doi.org\/10.1016\/j.jid.2019.09.029\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1016\/j.jid.2019.09.029<\/a><\/li>\n\n\n\n<li>Inzinger M, Wippel-Slupetzky K, Weger W, Stary G, Bauer W, Mlynek A, Kopp T. Failure rates and survival times of systemic and biologic therapies in treating psoriasis: a retrospective study. Journal of Dermatological Treatment. 2021;32(6):587\u2013593. <a href=\"https:\/\/doi.org\/10.1080\/09546634.2019.1688756\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1080\/09546634.2019.1688756<\/a><\/li>\n\n\n\n<li>Bajouri A, Dayani D, Taj-Sharghi A, Khodayar Pardo P, Tootoonchi M, Aghdami N, et al. Subcutaneous injection of allogeneic adipose-derived mesenchymal stromal cells in psoriasis plaques: clinical trial phase I. Cell Journal. 2023;25(6):363\u2013371. <a href=\"https:\/\/doi.org\/10.22074\/cellj.2023.1973793.1167\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.22074\/cellj.2023.1973793.1167<\/a><\/li>\n<\/ol>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\t\t<div data-elementor-type=\"section\" data-elementor-id=\"21880\" class=\"elementor elementor-21880\" data-elementor-post-type=\"elementor_library\">\n\t\t\t        <section class=\"elementor-section elementor-top-section elementor-element elementor-element-a6ebaad elementor-section-boxed elementor-section-height-default elementor-section-height-default pxl-row-scroll-none pxl-zoom-point-false pxl-section-overflow-visible pxl-section-fix-none pxl-bg-color-none pxl-section-overlay-none\" data-id=\"a6ebaad\" data-element_type=\"section\" data-e-type=\"section\">\n\n                \n                <div class=\"elementor-container elementor-column-gap-default \">\n           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