{"id":25191,"date":"2026-05-19T08:22:32","date_gmt":"2026-05-19T00:22:32","guid":{"rendered":"https:\/\/stemcell-malaysia.com\/?page_id=25191"},"modified":"2026-05-19T08:22:34","modified_gmt":"2026-05-19T00:22:34","slug":"multiple-sclerosis","status":"publish","type":"page","link":"https:\/\/stemcell-malaysia.com\/zh\/conditions\/multiple-sclerosis\/","title":{"rendered":"\u591a\u53d1\u6027\u786c\u5316\u75c7\u5e72\u7ec6\u80de\u6cbb\u7597\uff5c\u4e0d\u4f9d\u8d56\u5316\u7597\u51cf\u7f13DMT\u65e0\u6cd5\u963b\u6b62\u7684\u75be\u75c5\u8fdb\u5c55"},"content":{"rendered":"\n<h1 class=\"wp-block-heading has-text-align-center\">\u591a\u53d1\u6027\u786c\u5316\u75c7\u5e72\u7ec6\u80de\u6cbb\u7597\uff5c\u4e0d\u4f9d\u8d56\u5316\u7597\u51cf\u7f13DMT\u65e0\u6cd5\u963b\u6b62\u7684\u75be\u75c5\u8fdb\u5c55<\/h1>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"436\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Gemini_Generated_Image_4m8nzj4m8nzj4m8n.webp\" alt=\" \u591a\u53d1\u6027\u786c\u5316\u75c7\u60a3\u8005\u5728\u6668\u8d77\u65f6\u611f\u53d7\u5230\u624b\u6307\u9ebb\u6728\u4e0e\u4e0b\u80a2\u65e0\u529b\uff0c\u8c28\u614e\u5730\u8bc4\u4f30\u81ea\u5df1\u7684\u8eab\u4f53\u72b6\u51b5\" class=\"wp-image-25170\" style=\"aspect-ratio:1.8348992638512205;width:650px;height:auto\" srcset=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Gemini_Generated_Image_4m8nzj4m8nzj4m8n.webp 800w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Gemini_Generated_Image_4m8nzj4m8nzj4m8n-300x164.webp 300w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Gemini_Generated_Image_4m8nzj4m8nzj4m8n-768x419.webp 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption 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style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u76ee\u5f55<\/mark><\/h2>\n\n\n<div class=\"wp-block-aioseo-table-of-contents\"><ol><li><a class=\"aioseo-toc-item\" href=\"#aioseo-why-multiple-sclerosis-continues-to-progress-even-on-treatment-6\">\u591a\u53d1\u6027\u786c\u5316\u75c7\u5728DMT\u6cbb\u7597\u4e2d\u4ecd\u7136\u8fdb\u5c55\u7684\u539f\u56e0<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u591a\u53d1\u6027\u786c\u5316\u75c7\u75be\u75c5\u4fee\u6b63\u6cbb\u7597dmt\u89e6\u53ca\u4e0d\u5230\u7684\u9886\u57df-17\">\u591a\u53d1\u6027\u786c\u5316\u75c7\u75be\u75c5\u4fee\u6b63\u6cbb\u7597\uff08DMT\uff09\u89e6\u53ca\u4e0d\u5230\u7684\u9886\u57df<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-two-very-different-stem-cell-approaches-for-multiple-sclerosis-23\">\u591a\u53d1\u6027\u786c\u5316\u75c7\u7684\u4e24\u79cd\u5e72\u7ec6\u80de\u6cbb\u7597\u8def\u5f84<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-how-mesenchymal-stem-cells-work-in-multiple-sclerosis-three-mechanisms-34\">\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u4f5c\u7528\u4e8e\u591a\u53d1\u6027\u786c\u5316\u75c7\u7684\u4e09\u79cd\u673a\u5236<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u591a\u53d1\u6027\u786c\u5316\u75c7\u5e72\u7ec6\u80de\u4e34\u5e8a\u8bd5\u9a8c\u7684\u771f\u5b9e\u7ed3\u679c-60\">\u591a\u53d1\u6027\u786c\u5316\u75c7\u5e72\u7ec6\u80de\u4e34\u5e8a\u8bd5\u9a8c\u7684\u771f\u5b9e\u7ed3\u679c<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u9002\u5408\u4e0e\u4e0d\u9002\u5408\u63a5\u53d7\u591a\u53d1\u6027\u786c\u5316\u75c7\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u4eba\u7fa4-77\">\u9002\u5408\u4e0e\u4e0d\u9002\u5408\u63a5\u53d7\u591a\u53d1\u6027\u786c\u5316\u75c7\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u4eba\u7fa4<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u4e00\u4f4d\u591a\u53d1\u6027\u786c\u5316\u75c7\u60a3\u8005\u5e72\u7ec6\u80de\u6cbb\u7597\u540e\u7684\u4e00\u5e74\u968f\u8bbf-90\">\u4e00\u4f4d\u591a\u53d1\u6027\u786c\u5316\u75c7\u60a3\u8005\u5e72\u7ec6\u80de\u6cbb\u7597\u540e\u7684\u4e00\u5e74\u968f\u8bbf<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u591a\u53d1\u6027\u786c\u5316\u75c7\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u98ce\u9669\u4e0e\u8fb9\u754c-112\">\u591a\u53d1\u6027\u786c\u5316\u75c7\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u98ce\u9669\u4e0e\u8fb9\u754c<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-faq-about-multiple-sclerosis-stem-cell-therapy-105\">\u5173\u4e8e\u591a\u53d1\u6027\u786c\u5316\u75c7\u5e72\u7ec6\u80de\u7597\u6cd5\u7684\u5e38\u89c1\u95ee\u9898<\/a><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-a-conversation-about-your-specific-multiple-sclerosis-case-127\">\u5173\u4e8e\u60a8\u5177\u4f53\u60c5\u51b5\u7684\u54a8\u8be2<\/a><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-references-130\">\u53c2\u8003\u6587\u732e<\/a><\/li><\/ol><\/div>\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-why-multiple-sclerosis-continues-to-progress-even-on-treatment-6\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u591a\u53d1\u6027\u786c\u5316\u75c7\u5728DMT\u6cbb\u7597\u4e2d\u4ecd\u7136\u8fdb\u5c55\u7684\u539f\u56e0<\/mark><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-the-autoimmune-damage-cycle-in-multiple-sclerosis-7\">\u81ea\u8eab\u514d\u75ab\u7cfb\u7edf&#8221;\u8bef\u4f24&#8221;\u624d\u662f\u591a\u53d1\u6027\u786c\u5316\u75c7\u7684\u6838\u5fc3<\/h3>\n\n\n\n<p 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id=\"aioseo-two-very-different-stem-cell-approaches-for-multiple-sclerosis-23\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u591a\u53d1\u6027\u786c\u5316\u75c7\u7684\u4e24\u79cd\u5e72\u7ec6\u80de\u6cbb\u7597\u8def\u5f84<\/mark><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"800\" height=\"436\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-image-1-6.webp\" alt=\"\u591a\u53d1\u6027\u786c\u5316\u75c7\u7684\u4e24\u79cd\u5e72\u7ec6\u80de\u6cbb\u7597\u8def\u5f84\u2014\u2014HSCT\u9020\u8840\u5e72\u7ec6\u80de\u79fb\u690d\uff08\u542b\u5316\u7597\uff09\u4e0eMSC\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\uff08\u4e0d\u542b\u5316\u7597\uff09\u7684\u5bf9\u6bd4\u56fe\u89e3\" class=\"wp-image-25194\" style=\"aspect-ratio:1.8348992638512205;width:615px;height:auto\" srcset=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-image-1-6.webp 800w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-image-1-6-300x164.webp 300w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-image-1-6-768x419.webp 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption class=\"wp-element-caption\">HSCT\u4e0eMSC\u6cbb\u7597\u7ecf\u5e38\u88ab\u653e\u5728\u540c\u4e00\u4e2a&#8221;\u5e72\u7ec6\u80de\u6cbb\u7597&#8221;\u7684\u6807\u7b7e\u4e0b\u8ba8\u8bba\uff0c\u4f46\u4e8c\u8005\u5728\u751f\u7269\u5b66\u673a\u5236\u4e0e\u64cd\u4f5c\u6d41\u7a0b\u4e0a\u662f\u5b8c\u5168\u4e0d\u540c\u7684\u4e24\u79cd\u65b9\u6cd5\u3002<\/figcaption><\/figure>\n<\/div>\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-hsct-for-multiple-sclerosis-powerful-but-aggressive-24\">\u591a\u53d1\u6027\u786c\u5316\u75c7\u7684HSCT\uff1a\u5f3a\u529b\u4f46\u4ee3\u4ef7\u4e0d\u5c0f\u7684\u8def\u5f84<\/h3>\n\n\n\n<p 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SF-36\uff08\u751f\u6d3b\u8d28\u91cf\uff09\u7b49\u5404\u9879\u6307\u6807\u5747\u663e\u793a\u6539\u5584\u3002\u6ca1\u6709\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\uff0c\u5e38\u89c1\u526f\u4f5c\u7528\u662f\u5934\u75db\u548c\u75b2\u52b3\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u66f4\u8fd1\u7684Shokati\u7b49\uff08\u300a\u79d1\u5b66\u62a5\u544a\u300b2025\uff09\u57285\u540d\u7ee7\u53d1\u8fdb\u5c55\u578bMS\u60a3\u8005\u4e2d\u8fdb\u884c\u4e86\u80ce\u76d8\u6765\u6e90MSC\u7684\u2160\u671f\u8bd5\u9a8c\uff0c\u62a5\u544a\u4e86\u5b89\u5168\u6027\u4ee5\u53ca\u6b8b\u969c\u8bc4\u5206\u7684\u7a33\u5b9a\u6216\u6539\u5584\u4fe1\u53f7\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2025\u5e74\u300aMultiple Sclerosis and Related 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class=\"wp-block-paragraph\">\u6211\u4eec\u7684\u514d\u8d39\u7ebf\u4e0a\u54a8\u8be2\u6b63\u662f\u4e3a\u8fd9\u6837\u7684\u5bf9\u8bdd\u51c6\u5907\u7684\u3002\u4e0d\u662f\u8981\u60a8\u5f53\u573a\u505a\u51b3\u5b9a\uff0c\u800c\u662f\u548c\u60a8\u4e00\u8d77\u770b\u4e00\u770bMRI\u5386\u53f2\u3001DMT\u8bb0\u5f55\u3001\u5f53\u524d\u72b6\u6001\uff0c\u7136\u540e\u8bda\u5b9e\u5730\u544a\u8bc9\u60a8\uff1a\u4ece\u6211\u4eec\u7684\u89d2\u5ea6\u770b\uff0cMSC\u6cbb\u7597\u5bf9\u60a8\u662f\u4e0d\u662f\u4e00\u4e2a\u5408\u7406\u7684\u9009\u9879\uff1b\u5982\u679c\u4e0d\u662f\uff0c\u539f\u56e0\u662f\u4ec0\u4e48\u3002\u51b3\u5b9a\u53ef\u4ee5\u6162\u6162\u518d\u505a\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-references-130\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u53c2\u8003\u6587\u732e<\/mark><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Uccelli A, Laroni A, Ali R, et al. Safety, tolerability, and activity of mesenchymal stem cells versus placebo in multiple sclerosis (MESEMS): a phase 2, randomised, double-blind crossover trial. <em>Lancet Neurology<\/em>. 2021;20(11):917-929. <a href=\"https:\/\/doi.org\/10.1016\/S1474-4422(21)00301-X\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1016\/S1474-4422(21)00301-X<\/a><\/li>\n\n\n\n<li>Riordan NH, Morales I, Fern\u00e1ndez G, et al. Clinical feasibility of umbilical cord tissue-derived mesenchymal stem cells in the treatment of multiple sclerosis. <em>Journal of Translational Medicine<\/em>. 2018;16:57. <a href=\"https:\/\/doi.org\/10.1186\/s12967-018-1433-7\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1186\/s12967-018-1433-7<\/a><\/li>\n\n\n\n<li>Shokati A, Nikbakht M, Sahraian MA, et al. Cell therapy with placenta-derived mesenchymal stem cells for secondary progressive multiple sclerosis patients in a phase 1 clinical trial. <em>Scientific Reports<\/em>. 2025;15:16005. <a href=\"https:\/\/doi.org\/10.1038\/s41598-025-00590-6\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1038\/s41598-025-00590-6<\/a><\/li>\n\n\n\n<li>Walton C, King R, Rechtman L, et al. Rising prevalence of multiple sclerosis worldwide: Insights from the Atlas of MS, third edition. <em>Multiple Sclerosis Journal<\/em>. 2020;26(14):1816-1821. <a href=\"https:\/\/doi.org\/10.1177\/1352458520970841\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1177\/1352458520970841<\/a><\/li>\n\n\n\n<li>Sheikhi K, Ghaderi S, Firouzi H, et al. Recent advances in mesenchymal stem cell therapy for multiple sclerosis: clinical applications and challenges. <em>Frontiers in Cell and Developmental Biology<\/em>. 2025;13:1517369. <a href=\"https:\/\/doi.org\/10.3389\/fcell.2025.1517369\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.3389\/fcell.2025.1517369<\/a><\/li>\n\n\n\n<li>Muraro PA, Pasquini M, Atkins HL, et al. Long-term outcomes after autologous hematopoietic stem cell transplantation for multiple sclerosis. <em>JAMA Neurology<\/em>. 2017;74(4):459-469. <a href=\"https:\/\/doi.org\/10.1001\/jamaneurol.2016.5867\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1001\/jamaneurol.2016.5867<\/a><\/li>\n\n\n\n<li>Sormani MP, Muraro PA, Schiavetti I, et al. Autologous hematopoietic stem cell transplantation in multiple sclerosis. <em>Neurology<\/em>. 2017;88(22):2115-2122. <a href=\"https:\/\/doi.org\/10.1212\/WNL.0000000000003987\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1212\/WNL.0000000000003987<\/a><\/li>\n\n\n\n<li>Cohen JA, Imrey PB, Planchon SM, et al. Pilot trial of intravenous autologous culture-expanded mesenchymal stem cell transplantation in multiple sclerosis. <em>Multiple Sclerosis Journal<\/em>. 2018;24(4):501-511. <a href=\"https:\/\/doi.org\/10.1177\/1352458517703802\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1177\/1352458517703802<\/a><\/li>\n\n\n\n<li>Mesenchymal stem cells in clinical trials for multiple sclerosis: A systematic literature review and review of clinical trials. <em>Multiple Sclerosis and Related Disorders<\/em>. 2025. <a href=\"https:\/\/doi.org\/10.1016\/j.msard.2025.106492\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1016\/j.msard.2025.106492<\/a><\/li>\n\n\n\n<li>GBD 2021 Epidemiology of Multiple Sclerosis Collaborators. Epidemiology of Multiple Sclerosis: Global, Regional, National and Sub-National-Level Estimates and Future Projections. <em>Journal of Epidemiology and Global Health<\/em>. 2025. <a href=\"https:\/\/doi.org\/10.1007\/s44197-025-00353-6\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1007\/s44197-025-00353-6<\/a><\/li>\n<\/ol>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\t\t<div data-elementor-type=\"section\" data-elementor-id=\"21880\" class=\"elementor elementor-21880\" data-elementor-post-type=\"elementor_library\">\n\t\t\t        <section class=\"elementor-section elementor-top-section elementor-element elementor-element-a6ebaad elementor-section-boxed elementor-section-height-default elementor-section-height-default pxl-row-scroll-none pxl-zoom-point-false pxl-section-overflow-visible pxl-section-fix-none pxl-bg-color-none pxl-section-overlay-none\" data-id=\"a6ebaad\" data-element_type=\"section\" 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