{"id":25159,"date":"2026-05-19T08:22:54","date_gmt":"2026-05-19T00:22:54","guid":{"rendered":"https:\/\/stemcell-malaysia.com\/?page_id=25159"},"modified":"2026-07-31T12:28:10","modified_gmt":"2026-07-31T04:28:10","slug":"post-stroke-sequelae","status":"publish","type":"page","link":"https:\/\/stemcell-malaysia.com\/zh\/conditions\/post-stroke-sequelae\/","title":{"rendered":"\u8111\u5352\u4e2d\u540e\u9057\u75c7\u5e72\u7ec6\u80de\u6cbb\u7597\uff5c\u5eb7\u590d\u8fdb\u5165\u74f6\u9888\u540e\u8fd8\u80fd\u7ee7\u7eed\u6062\u590d\u5417?"},"content":{"rendered":"\n<h1 class=\"wp-block-heading has-text-align-center\">\u8111\u5352\u4e2d\u540e\u9057\u75c7\u5e72\u7ec6\u80de\u6cbb\u7597\uff5c\u5eb7\u590d\u8fdb\u5165\u74f6\u9888\u540e\u8fd8\u80fd\u7ee7\u7eed\u6062\u590d\u5417?<\/h1>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"436\" 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class=\"wp-block-paragraph\">\u7ec6\u80de\u7684\u6765\u6e90\u4e0d\u662f\u5355\u7eaf\u7684\u6280\u672f\u7ec6\u8282\u95ee\u9898\u3002\u5bf9\u4e8e\u4e00\u4f4d\u516d\u4e03\u5341\u5c81\u7684\u8111\u5352\u4e2d\u60a3\u8005\u6765\u8bf4,\u5065\u5eb7\u65b0\u751f\u513f\u6765\u6e90\u7684\u7ec6\u80de\u548c\u81ea\u5df1\u4f53\u5185\u7684\u7ec6\u80de\u4e4b\u95f4\u7684\u5dee\u522b,\u4f1a\u76f4\u63a5\u5f71\u54cd\u5230\u8fbe\u8111\u90e8\u7684\u4fe1\u53f7\u6d3b\u6027\u7684\u5f3a\u5ea6\u548c\u8d28\u91cf\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-what-clinical-trials-show-for-post-stroke-sequelae-stem-cell-therapy-49\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u8111\u5352\u4e2d\u540e\u9057\u75c7\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u4e34\u5e8a\u8bd5\u9a8c\u6570\u636e<\/mark><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"800\" height=\"720\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Image-2-3.webp\" alt=\"\u6162\u6027\u671f\u8111\u5352\u4e2d\u540e\u9057\u75c7\u60a3\u8005\u5e72\u7ec6\u80de\u6cbb\u7597\u540eFugl-Meyer\u8fd0\u52a8\u8bc4\u5206\u6539\u5584\u7684\u67f1\u72b6\u56fe,\u57fa\u4e8eSteinberg\u7b492016\u5e74\u53d1\u8868\u7684\u4e34\u5e8a\u8bd5\u9a8c\u6570\u636e\" class=\"wp-image-25162\" style=\"aspect-ratio:1.0796170176388453;width:462px;height:auto\" srcset=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Image-2-3.webp 800w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Image-2-3-300x270.webp 300w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Image-2-3-768x691.webp 768w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Image-2-3-789x710.webp 789w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption class=\"wp-element-caption\">Steinberg\u7b492016\u5e74\u53d1\u8868\u4e8eStroke\u6742\u5fd7\u7684SB623\u7ec6\u80de\u8bd5\u9a8c,\u6162\u6027\u671f\u8111\u5352\u4e2d\u60a3\u8005\u5728\u6cbb\u7597\u540e12\u4e2a\u6708Fugl-Meyer\u8fd0\u52a8\u8bc4\u5206\u5e73\u5747\u6539\u558411.4\u5206\u3002<\/figcaption><\/figure>\n<\/div>\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-major-stroke-stem-cell-trials-and-their-numbers-50\">\u4e3b\u8981\u4e34\u5e8a\u8bd5\u9a8c\u7684\u5177\u4f53\u6570\u636e<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u8111\u5352\u4e2d\u5e72\u7ec6\u80de\u6cbb\u7597\u5728\u518d\u751f\u533b\u5b66\u9886\u57df\u4e2d\u662f\u76f8\u5bf9\u6210\u719f\u7684\u7814\u7a76\u65b9\u5411,\u81ea2000\u5e74\u4ee3\u521d\u5df2\u5f00\u5c55\u591a\u9879\u5bf9\u7167\u8bd5\u9a8c\u3002\u4e0b\u9762\u6211\u4eec\u7528\u5177\u4f53\u7684\u6570\u5b57\u6765\u4ecb\u7ecd\u51e0\u4e2a\u6709\u4ee3\u8868\u6027\u7684\u7814\u7a76\u2014\u2014\u56e0\u4e3a\u542b\u7cca\u7684\u603b\u7ed3\u5bf9\u60a3\u8005\u505a\u51b3\u7b56\u6ca1\u6709\u5e2e\u52a9\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u65af\u5766\u798f\u5927\u5b66\u7684SB623\u7814\u7a76(Steinberg\u7b49,\u53d1\u8868\u4e8eStroke\u6742\u5fd7,2016\u5e74),\u662f\u65e9\u671f\u6700\u5177\u5f71\u54cd\u529b\u76841\/2a\u671f\u4e34\u5e8a\u8bd5\u9a8c\u4e4b\u4e00\u3002\u5165\u900918\u540d\u53d1\u75c5\u540e6\u4e2a\u6708\u81f33\u5e74\u7684\u6162\u6027\u671f\u8111\u5352\u4e2d\u60a3\u8005,\u8fd0\u52a8\u529f\u80fd\u969c\u788d\u5904\u4e8e\u7a33\u5b9a\u72b6\u6001\u3002\u4f7f\u7528\u7684\u7ec6\u80de\u662f\u4fee\u9970\u8fc7\u7684\u5f02\u4f53\u9aa8\u9ad3\u6765\u6e90MSC,\u901a\u8fc7\u7acb\u4f53\u5b9a\u5411\u795e\u7ecf\u5916\u79d1\u624b\u672f,\u4e00\u6b21\u6027\u6ce8\u5165\u635f\u4f24\u533a\u9644\u8fd1\u7684\u8111\u7ec4\u7ec7\u5185\u300212\u4e2a\u6708\u65f6,\u60a3\u8005\u5728\u591a\u4e2a\u6807\u51c6\u5316\u91cf\u8868\u4e0a\u90fd\u663e\u793a\u7edf\u8ba1\u5b66\u663e\u8457\u6539\u5584:\u6b27\u6d32\u5352\u4e2d\u91cf\u8868\u3001NIHSS(\u7f8e\u56fd\u56fd\u7acb\u536b\u751f\u7814\u7a76\u9662\u5352\u4e2d\u91cf\u8868),\u4ee5\u53ca\u6700\u53d7\u5173\u6ce8\u7684Fugl-Meyer\u8fd0\u52a8\u529f\u80fd\u8bc4\u5206(\u8fd0\u52a8\u6062\u590d\u7684\u6807\u51c6\u91cf\u8868),\u5e73\u5747\u6539\u5584\u4e8611.4\u5206\u3002\u4e00\u822c\u6765\u8bf4,\u8fd9\u4e2a\u91cf\u8868\u4e0a4\u52306\u5206\u7684\u53d8\u5316\u5c31\u88ab\u8ba4\u4e3a\u5177\u6709\u4e34\u5e8a\u610f\u4e49,\u800c11\u5206\u4ee5\u4e0a\u7684\u53d8\u5316\u5c5e\u4e8e\u5f88\u503c\u5f97\u5173\u6ce8\u7684\u5e45\u5ea6\u3002\u6cbb\u7597\u76f8\u5173\u4e0d\u826f\u4e8b\u4ef6\u5927\u591a\u4e0e\u5916\u79d1\u6ce8\u5c04\u64cd\u4f5c\u672c\u8eab\u6709\u5173,\u800c\u4e0d\u662f\u7ec6\u80de\u672c\u8eab\u9020\u6210\u7684\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">PISCES\u9879\u76ee(Pilot Investigation of Stem Cells in Stroke)\u4f7f\u7528\u7684\u662f\u4e00\u79cd\u6761\u4ef6\u6027\u6c38\u751f\u5316\u7684\u4eba\u795e\u7ecf\u5e72\u7ec6\u80de\u7cfb(CTX0E03),\u540c\u6837\u4ee5\u624b\u672f\u65b9\u5f0f\u6ce8\u5165\u8111\u5185\u3002Muir\u7b49\u4eba2020\u5e74\u53d1\u8868\u7684PISCES-II\u8bd5\u9a8c,\u5165\u900923\u540d\u53d1\u75c5\u540e6\u4e2a\u6708\u81f35\u5e74\u3001\u60a3\u6709\u4e0a\u80a2\u504f\u762b\u7684\u6162\u6027\u671f\u60a3\u8005\u3002\u4e3b\u8981\u7ec8\u70b9\u662f\u6cbb\u7597\u540e3\u4e2a\u6708\u65f6,Action Research Arm Test(ARAT,\u4e0a\u80a2\u529f\u80fd\u6807\u51c6\u8bc4\u4f30)\u662f\u5426\u6539\u55842\u5206\u6216\u4ee5\u4e0a\u2014\u2014\u4e5f\u5c31\u662f\u60a3\u4fa7\u624b\u5728\u65e5\u5e38\u4f7f\u7528\u4e2d\u662f\u5426\u6709\u53ef\u89c1\u7684\u8fdb\u6b65\u300223\u540d\u60a3\u8005\u4e2d\u670912\u540d\u8fbe\u5230\u4e86\u8fd9\u4e2a\u6807\u51c6,\u536052%\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2019\u5e74\u53d1\u8868\u4e8eStroke\u6742\u5fd7\u7684Levy\u7b49\u4eba\u7814\u7a76\u91c7\u7528\u4e86\u4e0d\u540c\u7684\u8def\u7ebf:\u5bf936\u540d\u6162\u6027\u671f\u8111\u5352\u4e2d\u60a3\u8005\u4f7f\u7528\u5f02\u4f53\u9aa8\u9ad3\u6765\u6e90MSC\u7684\u9759\u8109\u8f93\u6ce8(\u800c\u4e0d\u662f\u624b\u672f\u6ce8\u5165)\u3002\u8fd9\u9879\u7814\u7a76\u8bc4\u4f30\u7684\u662f\u5b89\u5168\u6027\u4e0e\u521d\u6b65\u7597\u6548\u3002\u8f93\u6ce8\u8010\u53d7\u826f\u597d,\u65e0\u4e25\u91cd\u6cbb\u7597\u76f8\u5173\u4e0d\u826f\u4e8b\u4ef6\u3002\u5728Barthel\u6307\u6570(\u65e5\u5e38\u751f\u6d3b\u72ec\u7acb\u6027\u7684\u8861\u91cf)\u548c\u6539\u826fRankin\u91cf\u8868(\u6574\u4f53\u6b8b\u75be\u7a0b\u5ea6\u7684\u8861\u91cf)\u4e0a,\u6cbb\u7597\u7ec4\u89c2\u5bdf\u5230\u4e86\u529f\u80fd\u6539\u5584\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The Lancet Neurology\u6742\u5fd72017\u5e74\u53d1\u8868\u7684MASTERS\u8bd5\u9a8c(Hess\u7b49)\u91c7\u7528\u7684\u662f\u53e6\u4e00\u79cd\u8def\u5f84:\u5bf9\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d\u53d1\u75c5\u540e24\u523048\u5c0f\u65f6\u4e4b\u5185\u7684\u60a3\u8005\u8fdb\u884cMultiStem(\u76f8\u5173\u5f02\u4f53\u7ec6\u80de\u4ea7\u54c1)\u9759\u8109\u8f93\u6ce8\u3002\u8fd9\u9879\u8bd5\u9a8c\u7684\u603b\u4f53\u4e3b\u8981\u7597\u6548\u7ec8\u70b9\u672a\u8fbe\u5230,\u4f46\u4e8b\u5148\u8bbe\u5b9a\u7684\u65e9\u671f\u6cbb\u7597\u4e9a\u7ec4\u5206\u6790\u663e\u793a\u51fa\u83b7\u76ca\u4fe1\u53f7\u3002\u540e\u7eed\u7814\u7a76\u9879\u76ee\u4ecd\u5728\u7ee7\u7eed\u63a2\u7d22\u8fd9\u4e2a\u65b9\u5411\u3002<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-\u4e34\u5e8a\u4e0a\u6709\u610f\u4e49\u7684\u6539\u5584\u5728\u65e5\u5e38\u751f\u6d3b\u4e2d\u662f\u4ec0\u4e48\u6837\u5b50-59\">\u4e34\u5e8a\u4e0a\u6709\u610f\u4e49\u7684\u6539\u5584,\u5728\u65e5\u5e38\u751f\u6d3b\u4e2d\u662f\u4ec0\u4e48\u6837\u5b50<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u6211\u4eec\u60f3\u628a\u8fd9\u4e9b\u8bd5\u9a8c\u6570\u636e\u7ffb\u8bd1\u6210\u65e5\u5e38\u751f\u6d3b\u7684\u8bed\u8a00,\u56e0\u4e3a\u8bc4\u5206\u53d8\u5316\u672c\u8eab\u5f80\u5f80\u63a9\u76d6\u4e86\u5b83\u5bf9\u60a3\u8005\u771f\u5b9e\u751f\u6d3b\u7684\u610f\u4e49\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Fugl-Meyer\u4e0a\u7684\u4e34\u5e8a\u610f\u4e49\u6539\u5584,\u53ef\u80fd\u610f\u5473\u7740\u539f\u672c\u5b8c\u5168\u4e0d\u80fd\u63e1\u4f4f\u4efb\u4f55\u4e1c\u897f\u7684\u624b,\u53ef\u4ee5\u63e1\u4f4f\u624b\u673a\u6216\u8005\u8336\u676f\u4e86\u2014\u2014\u5373\u4fbf\u624b\u6307\u7684\u7cbe\u7ec6\u63a7\u5236\u4ecd\u7136\u53d7\u9650\u3002ARAT\u4e0a2\u5206\u7684\u6539\u5584,\u53ef\u80fd\u610f\u5473\u7740\u539f\u672c\u591f\u4e0d\u5230\u7684\u6401\u677f\u80fd\u591f\u5230\u4e86,\u539f\u672c\u634f\u4e0d\u4f4f\u7684\u7b14\u53ef\u4ee5\u634f\u4f4f\u4e86\u3002\u6539\u826fRankin\u91cf\u8868\u4e0a1\u5206\u7684\u5dee\u522b,\u53ef\u80fd\u5c31\u662f\u4ece\u52a9\u884c\u5668\u6362\u6210\u5355\u62d0,\u4ece\u5355\u62d0\u5230\u4e0d\u9700\u8981\u62d0\u6756\u72ec\u7acb\u884c\u8d70\u3002<\/p>\n\n\n\n<p 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data-wp-on--beforematch=\"actions.handleBeforeMatch\" id=\"accordion-item-4-panel\" role=\"region\" class=\"wp-block-accordion-panel is-layout-flow wp-block-accordion-panel-is-layout-flow\">\n<p class=\"wp-block-paragraph\">\u5df2\u53d1\u8868\u4e34\u5e8a\u8bd5\u9a8c\u7684\u968f\u8bbf\u671f\u4e00\u822c\u662f1\u52303\u5e74\uff0c\u5728\u8fd9\u4e2a\u8303\u56f4\u5185\uff0c\u6cbb\u7597\u540e6\u523012\u4e2a\u6708\u6240\u83b7\u5f97\u7684\u6539\u5584\u5f80\u5f80\u662f\u88ab\u7ef4\u6301\u4e0b\u6765\u7684\uff0c\u800c\u4e0d\u662f\u9010\u6e10\u6d88\u9000\u3002Steinberg 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style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-considering-your-options-for-post-stroke-sequelae-133\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u4e0b\u4e00\u6b65<\/mark><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u8bfb\u5230\u8fd9\u91cc\u7684\u60a8,\u53ef\u80fd\u6b63\u5728\u4e3a\u81ea\u5df1\u6216\u5bb6\u4eba\u8111\u5352\u4e2d\u4e4b\u540e\u7684\u6062\u590d\u8def\u5f84\u8ba4\u771f\u601d\u8003\u4e0b\u4e00\u6b65\u3002\u88ab\u544a\u77e5&#8221;\u6062\u590d\u5dee\u4e0d\u591a\u5230\u6b64\u4e3a\u6b62&#8221;\u7684\u90a3\u4e2a\u65f6\u523b\u7684\u5206\u91cf,\u6211\u4eec\u80fd\u591f\u7406\u89e3\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6211\u4eec\u63d0\u4f9b\u514d\u8d39\u7684\u5728\u7ebf\u54a8\u8be2\u3002\u5e26\u4e0a\u5f71\u50cf\u8d44\u6599\u3001\u5eb7\u590d\u5386\u53f2\u3001\u60a8\u624b\u8fb9\u5199\u4e0b\u6765\u7684\u95ee\u9898\u5c31\u53ef\u4ee5\u4e86\u3002\u5982\u679c\u60a8\u7684\u60c5\u51b5\u7b26\u5408\u73b0\u6709\u8bc1\u636e\u6240\u652f\u6301\u7684\u753b\u50cf,\u6211\u4eec\u4f1a\u544a\u8bc9\u60a8;\u5982\u679c\u4e0d\u7b26\u5408,\u6211\u4eec\u4e5f\u4f1a\u540c\u6837\u5982\u5b9e\u5730\u544a\u8bc9\u60a8\u3002\u7b2c\u4e00\u6b21\u54a8\u8be2\u4e0d\u9700\u8981\u505a\u4efb\u4f55\u51b3\u5b9a\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-references-137\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u53c2\u8003\u6587\u732e<\/mark><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>GBD 2019 Stroke Collaborators. &#8220;Global, regional, and national burden of stroke and its risk factors, 1990\u20132019: a systematic analysis for the Global Burden of Disease Study 2019.&#8221; The Lancet Neurology. 2021;20(10):795\u2013820. <a href=\"https:\/\/doi.org\/10.1016\/S1474-4422(21)00252-0\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1016\/S1474-4422(21)00252-0<\/a><\/li>\n\n\n\n<li>Steinberg GK, Kondziolka D, Wechsler LR, et al. &#8220;Clinical Outcomes of Transplanted Modified Bone Marrow\u2013Derived Mesenchymal Stem Cells in Stroke: A Phase 1\/2a Study.&#8221; Stroke. 2016;47(7):1817\u20131824. <a href=\"https:\/\/doi.org\/10.1161\/STROKEAHA.116.012995\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1161\/STROKEAHA.116.012995<\/a><\/li>\n\n\n\n<li>Kalladka D, Sinden J, Pollock K, et al. &#8220;Human neural stem cells in patients with chronic ischaemic stroke (PISCES): a phase 1, first-in-man study.&#8221; The Lancet. 2016;388(10046):787\u2013796. <a href=\"https:\/\/doi.org\/10.1016\/S0140-6736(16)30513-X\" 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ML, Crawford JR, Dib N, Verkh L, Tankovich N, Cramer SC. &#8220;Phase I\/II Study of Safety and Preliminary Efficacy of Intravenous Allogeneic Mesenchymal Stem Cells in Chronic Stroke.&#8221; Stroke. 2019;50(10):2835\u20132841. <a href=\"https:\/\/doi.org\/10.1161\/STROKEAHA.119.026318\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1161\/STROKEAHA.119.026318<\/a><\/li>\n\n\n\n<li>Savitz SI, Cramer SC, Wechsler L; STEPS 3 Consortium. &#8220;Stem cells as an emerging paradigm in stroke 3: enhancing the development of clinical trials.&#8221; Stroke. 2014;45(2):634\u2013639. <a href=\"https:\/\/doi.org\/10.1161\/STROKEAHA.113.003379\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1161\/STROKEAHA.113.003379<\/a><\/li>\n\n\n\n<li>Bergmann O, Bhardwaj RD, Bernard S, et al. &#8220;Evidence for cardiomyocyte renewal in humans.&#8221; Science. 2009;324(5923):98\u2013102. <a href=\"https:\/\/doi.org\/10.1126\/science.1164680\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1126\/science.1164680<\/a><\/li>\n<\/ol>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\t\t<div data-elementor-type=\"section\" data-elementor-id=\"21880\" class=\"elementor elementor-21880\" data-elementor-post-type=\"elementor_library\">\n\t\t\t        <section class=\"elementor-section elementor-top-section elementor-element elementor-element-a6ebaad elementor-section-boxed elementor-section-height-default elementor-section-height-default pxl-row-scroll-none pxl-zoom-point-false pxl-section-overflow-visible pxl-section-fix-none pxl-bg-color-none pxl-section-overlay-none\" data-id=\"a6ebaad\" data-element_type=\"section\" data-e-type=\"section\">\n\n                \n                <div class=\"elementor-container elementor-column-gap-default \">\n                <div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-d089a17 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