{"id":25060,"date":"2026-05-11T13:59:50","date_gmt":"2026-05-11T05:59:50","guid":{"rendered":"https:\/\/stemcell-malaysia.com\/?page_id=25060"},"modified":"2026-05-11T13:59:52","modified_gmt":"2026-05-11T05:59:52","slug":"severe-asthma","status":"publish","type":"page","link":"https:\/\/stemcell-malaysia.com\/zh\/conditions\/severe-asthma\/","title":{"rendered":"\u91cd\u75c7\u54ee\u5598\u7684\u5e72\u7ec6\u80de\u6cbb\u7597\uff5c\u4e0d\u52a0\u91cd\u6fc0\u7d20\u4e5f\u80fd\u7f13\u89e3\u6c14\u9053\u708e\u75c7\u5417"},"content":{"rendered":"\n<h1 class=\"wp-block-heading has-text-align-center\">\u91cd\u75c7\u54ee\u5598\u7684\u5e72\u7ec6\u80de\u6cbb\u7597\uff5c\u4e0d\u52a0\u91cd\u6fc0\u7d20\u4e5f\u80fd\u7f13\u89e3\u6c14\u9053\u708e\u75c7\u5417<\/h1>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"436\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Gemini_Generated_Image_rbvcftrbvcftrbvc-1.webp\" alt=\"\u4e2d\u5e74\u6210\u4eba\u4f7f\u7528\u5438\u5165\u5668\u7684\u753b\u9762\uff0c\u53cd\u6620\u91cd\u75c7\u54ee\u5598\u60a3\u8005\u65e5\u5e38\u63a7\u5236\u75c7\u72b6\u7684\u771f\u5b9e\u60c5\u5f62\" class=\"wp-image-25039\" style=\"aspect-ratio:1.8348992638512205;width:660px;height:auto\" srcset=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Gemini_Generated_Image_rbvcftrbvcftrbvc-1.webp 800w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Gemini_Generated_Image_rbvcftrbvcftrbvc-1-300x164.webp 300w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Gemini_Generated_Image_rbvcftrbvcftrbvc-1-768x419.webp 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption 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style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u76ee\u5f55<\/mark><\/h2>\n\n\n<div class=\"wp-block-aioseo-table-of-contents\"><ol><li><a class=\"aioseo-toc-item\" href=\"#aioseo-why-severe-asthma-resists-standard-control-8\">\u91cd\u75c7\u54ee\u5598\u4e3a\u4ec0\u4e48\u96be\u4ee5\u5f7b\u5e95\u63a7\u5236<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-ics\u751f\u7269\u5236\u5242\u4e0e\u53e3\u670d\u6fc0\u7d20\u7684\u73b0\u5b9e\u74f6\u9888-18\">ICS\u3001\u751f\u7269\u5236\u5242\u4e0e\u53e3\u670d\u6fc0\u7d20\u7684\u73b0\u5b9e\u74f6\u9888<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-how-mesenchymal-stem-cells-act-on-severe-asthma-inflammation-28\">\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u5982\u4f55\u4f5c\u7528\u4e8e\u91cd\u75c7\u54ee\u5598\u7684\u708e\u75c7<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u91cd\u75c7\u54ee\u5598\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u4e34\u5e8a\u4e0e\u4e34\u5e8a\u524d\u8bc1\u636e-45\">\u91cd\u75c7\u54ee\u5598\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u4e34\u5e8a\u4e0e\u4e34\u5e8a\u524d\u8bc1\u636e<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u91cd\u75c7\u54ee\u5598\u8868\u73b0\u578b\u4e0e\u9002\u5e94\u4eba\u7fa4\u5224\u65ad-59\">\u91cd\u75c7\u54ee\u5598\u8868\u73b0\u578b\u4e0e\u9002\u5e94\u4eba\u7fa4\u5224\u65ad<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u4e00\u4f4d\u60a3\u8005\u7684\u771f\u5b9e\u7ecf\u8fc7-70\">\u4e00\u4f4d\u60a3\u8005\u7684\u771f\u5b9e\u7ecf\u8fc7<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-the-treatment-process-for-severe-asthma-patients-in-malaysia-74\">\u9a6c\u6765\u897f\u4e9a\u7684\u6cbb\u7597\u6d41\u7a0b<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-honest-risks-and-limitations-of-severe-asthma-stem-cell-therapy-89\">\u91cd\u75c7\u54ee\u5598\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u98ce\u9669\u4e0e\u8bda\u5b9e\u7684\u5c40\u9650<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-severe-asthma-stem-cell-therapy-faq-100\">\u91cd\u5ea6\u54ee\u5598\u5e72\u7ec6\u80de\u6cbb\u7597\u5e38\u89c1\u95ee\u9898\u89e3\u7b54<\/a><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-if-you-are-considering-the-next-step-for-your-severe-asthma-106\">\u5982\u679c\u60a8\u6b63\u5728\u8003\u8651\u4e0b\u4e00\u6b65<\/a><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-references-112\">\u53c2\u8003\u6587\u732e<\/a><\/li><\/ol><\/div>\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-why-severe-asthma-resists-standard-control-8\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u91cd\u75c7\u54ee\u5598\u4e3a\u4ec0\u4e48\u96be\u4ee5\u5f7b\u5e95\u63a7\u5236<\/mark><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-the-persistent-inflammation-that-defines-severe-asthma-9\">\u6301\u7eed\u88ab\u6fc0\u6d3b\u7684\u6c14\u9053\u514d\u75ab\u7cfb\u7edf<\/h3>\n\n\n\n<p 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class=\"wp-block-paragraph\">\u5bf9\u5927\u591a\u6570\u54ee\u5598\u60a3\u8005\u6765\u8bf4\uff0c\u5438\u5165\u6fc0\u7d20\uff08ICS\u2014\u2014\u6bcf\u65e5\u5438\u5165\u7684\u6297\u708e\u4e3b\u836f\uff0c\u5982\u6c1f\u66ff\u5361\u677e\u3001\u5e03\u5730\u5948\u5fb7\u3001\u500d\u6c2f\u7c73\u677e\uff09\u548c\u957f\u6548\u03b22\u53d7\u4f53\u6fc0\u52a8\u5242\uff08LABA\u2014\u2014\u6c14\u7ba1\u6269\u5f20\u5242\uff09\u7684\u8054\u5408\u65b9\u6848\uff0c\u8db3\u4ee5\u628a\u75c7\u72b6\u538b\u5728\u53ef\u63a5\u53d7\u7684\u6c34\u5e73\u3002\u8fd9\u5957\u65b9\u6848\u5728\u56fd\u5185\u88ab\u5e7f\u6cdb\u4f7f\u7528\uff0c\u672c\u8eab\u5c31\u662f\u7597\u6548\u5f97\u5230\u9a8c\u8bc1\u7684\u4f53\u73b0\u3002<\/p>\n\n\n\n<p 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id=\"aioseo-\u751f\u7269\u5236\u5242\u7528\u4e0d\u4e0a\u7528\u4e0a\u540e\u6548\u679c\u6709\u9650\u7684\u60a3\u8005-22\">\u751f\u7269\u5236\u5242\u7528\u4e0d\u4e0a\u3001\u7528\u4e0a\u540e\u6548\u679c\u6709\u9650\u7684\u60a3\u8005<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u8fc7\u53bb\u5341\u51e0\u5e74\u91cc\uff0c\u4e2d\u56fd\u91cd\u75c7\u54ee\u5598\u6cbb\u7597\u6700\u5927\u7684\u8fdb\u5c55\uff0c\u662f\u51e0\u79cd\u751f\u7269\u5236\u5242\uff08\u5982\u5965\u9a6c\u73e0\u5355\u6297\u3001\u7f8e\u6cca\u5229\u5355\u6297\u3001\u8d1d\u90a3\u5229\u73e0\u5355\u6297\u3001\u5ea6\u666e\u5229\u5c24\u5355\u6297\u7b49\uff09\u7684\u9010\u6b65\u4e0a\u5e02\u4e0e\u53ef\u53ca\u6027\u7684\u6539\u5584\u3002\u8fd9\u4e9b\u836f\u7269\u5206\u522b\u9488\u5bf9IgE\u3001IL-5\u3001IL-5\u53d7\u4f53\u3001IL-4\/IL-13\u7b49\u7279\u5b9a\u4fe1\u53f7\u901a\u8def\uff0c\u5bf9Type 2 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class=\"wp-block-paragraph\">\u4f46\u771f\u5b9e\u4e16\u754c\u6570\u636e\u63ed\u793a\u51fa\u66f4\u590d\u6742\u7684\u73b0\u5b9e\u3002\u7ea625%\u7684\u60a3\u8005\u5bf9\u7b2c\u4e00\u79cd\u751f\u7269\u5236\u5242\u572812\u4e2a\u6708\u65f6\u4e0d\u663e\u793a\u5177\u6709\u4e34\u5e8a\u610f\u4e49\u7684\u53cd\u5e94\u3002\u6700\u521d\u6709\u53cd\u5e94\u7684\u60a3\u8005\u4e2d\uff0c\u76f8\u5f53\u6bd4\u4f8b\u4f1a\u968f\u65f6\u95f4\u51fa\u73b0&#8221;\u7ee7\u53d1\u6027\u5931\u6548&#8221;\u2014\u2014\u836f\u7269\u9010\u6e10\u5931\u53bb\u6548\u529b\uff0c\u5e38\u4e0e\u4f53\u5185\u4ea7\u751f\u6297\u836f\u6297\u4f53\u6709\u5173\u3002\u7b2c\u4e00\u79cd\u5931\u8d25\u540e\uff0c\u5bf9\u7b2c\u4e8c\u79cd\u7684\u53cd\u5e94\u7387\u901a\u5e38\u66f4\u4f4e\uff1b\u4ee5\u6b64\u7c7b\u63a8\u3002\u6b64\u5916\uff0c\u751f\u7269\u5236\u5242\u4e3b\u8981\u9488\u5bf9\u7684Type 2 high\u5360\u91cd\u75c7\u54ee\u5598\u768460-80%\uff0c\u4f46Type 2 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class=\"wp-block-paragraph\">\u4f1a\u8ba4\u771f\u8003\u8651\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u60a3\u8005\uff0c\u51e0\u4e4e\u90fd\u5230\u4e86\u8fd9\u4e2a\u8282\u70b9\uff1a\u751f\u7269\u5236\u5242\u6548\u679c\u6709\u9650\u3001\u53e3\u670d\u6fc0\u7d20\u79bb\u4e0d\u5f00\u3001\u526f\u4f5c\u7528\u5f00\u59cb\u53cd\u8fc7\u6765\u5f71\u54cd\u751f\u6d3b\u8d28\u91cf\u3002\u4ed6\u4eec\u4e0d\u662f\u5728\u8ffd\u6c42\u5947\u8ff9\uff0c\u800c\u662f\u5728\u4f20\u7edf\u8def\u5f84\u7684\u6210\u672c-\u6536\u76ca\u8d26\u9762\u4e0a\u5df2\u7ecf\u4e0d\u5e73\u8861\u4e4b\u540e\uff0c\u5728\u5bfb\u627e\u4e0b\u4e00\u6b65\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-how-mesenchymal-stem-cells-act-on-severe-asthma-inflammation-28\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u5982\u4f55\u4f5c\u7528\u4e8e\u91cd\u75c7\u54ee\u5598\u7684\u708e\u75c7<\/mark><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"800\" height=\"436\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-Image-24.webp\" alt=\"\u91cd\u75c7\u54ee\u5598\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u4e09\u5927\u4f5c\u7528\u673a\u5236\u793a\u610f\u56fe\uff1aTh2\/ILC2\u6291\u5236\u3001\u55dc\u9178\u6027\u708e\u75c7\u51cf\u5c11\u3001\u6c14\u9053\u91cd\u5851\u51cf\u7f13\" class=\"wp-image-25062\" style=\"aspect-ratio:1.8348992638512205;width:666px;height:auto\" srcset=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-Image-24.webp 800w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-Image-24-300x164.webp 300w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-Image-24-768x419.webp 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption class=\"wp-element-caption\">\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u4e0d\u662f\u963b\u65ad\u5355\u4e00\u4fe1\u53f7\u5206\u5b50\uff0c\u800c\u662f\u4ece\u4e09\u4e2a\u4e92\u76f8\u91cd\u53e0\u7684\u751f\u7269\u901a\u8def\u540c\u65f6\u4f5c\u7528\u4e8e\u91cd\u75c7\u54ee\u5598\u7684\u708e\u75c7\u73af\u5883\u3002<\/figcaption><\/figure>\n<\/div>\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-suppressing-th2-cells-and-ilc2s-in-severe-asthma-31\">\u8ba9Th2\u7ec6\u80de\u4e0eILC2\u5b89\u9759\u4e0b\u6765<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08Mesenchymal Stem Cells\uff0c\u7b80\u79f0MSC\uff09\u662f\u9aa8\u9ad3\u3001\u8102\u80aa\u7ec4\u7ec7\u3001\u8110\u5e26\u7ec4\u7ec7\u7b49\u91cc\u81ea\u7136\u5b58\u5728\u7684\u4e00\u7c7b\u95f4\u8d28\u7ec6\u80de\u3002\u5b83\u672c\u8eab\u5e76\u4e0d\u50cf\u836f\u7269\u90a3\u6837\u8d77\u4f5c\u7528\u3002MSC\u7684\u672c\u8d28\uff0c\u662f\u901a\u8fc7\u91ca\u653e\u7ec6\u80de\u56e0\u5b50\uff08\u7ec6\u80de\u5206\u6ccc\u7684\u4fe1\u53f7\u5206\u5b50\uff09\u3001\u751f\u957f\u56e0\u5b50\u548c\u5916\u6ccc\u4f53\uff08\u7ec6\u80de\u819c\u5305\u88f9\u7684\u5c0f\u578b\u4fe1\u606f\u8f7d\u4f53\uff09\u7b49\u5206\u6ccc\u4ea7\u7269\uff0c\u6765\u6539\u53d8\u5468\u56f4\u7684\u514d\u75ab\u73af\u5883\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Shin\u7b49\u4eba\u4e8e2021\u5e74\u5728\u300aMolecules and Cells\u300b\u6742\u5fd7\u4e0a\u53d1\u8868\u7684\u7814\u7a76\u4e2d\u68c0\u6d4b\u4e86\u4eba\u8110\u5e26\u8840\u6765\u6e90MSC\u5728\u4e24\u79cd\u91cd\u75c7\u54ee\u5598\u5c0f\u9f20\u6a21\u578b\u4e2d\u7684\u4f5c\u7528\u3002MSC\u6cbb\u7597\u5728\u4e24\u79cd\u6a21\u578b\u4e2d\u90fd\u51cf\u5c11\u4e86\u80ba\u90e8Type 2\u578b\u708e\u75c7\u3002\u5728\u4f53\u5916\u7ec6\u80de\u5171\u57f9\u517b\u5b9e\u9a8c\u4e2d\uff0cMSC\u76f4\u63a5\u964d\u4f4e\u4e86\u5206\u5316\u540e\u7684\u5c0f\u9f20Th2\u7ec6\u80de\u2014\u2014\u4ee5\u53ca\u6765\u81ea\u4eba\u7c7b\u54ee\u5598\u60a3\u8005\u7684\u5916\u5468\u8840\u5355\u4e2a\u6838\u7ec6\u80de\u2014\u2014\u5206\u6cccIL-5\u4e0eIL-13\u7684\u91cf\u3002MSC\u4e0d\u662f\u50cf\u751f\u7269\u5236\u5242\u90a3\u6837&#8221;\u5c01\u5835&#8221;\u8fd9\u4e9b\u7ec6\u80de\u56e0\u5b50\uff0c\u800c\u662f&#8221;\u8ba9\u4ea7\u751f\u8fd9\u4e9b\u56e0\u5b50\u7684\u7ec6\u80de\u5b89\u9759\u4e0b\u6765&#8221;\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u53e6\u6709\u7814\u7a76\u663e\u793a\uff0c\u5c06\u8110\u5e26MSC\u76f4\u63a5\u7ed9\u4e88\u54ee\u5598\u6a21\u578b\u5c0f\u9f20\u7684\u6c14\u9053\uff0c\u53ef\u964d\u4f4e\u6c14\u9053\u9ad8\u53cd\u5e94\u6027\uff0c\u51cf\u5c11\u80ba\u90e8Th2\u7ec6\u80de\u4e0eILC2\u7684\u6570\u91cf\uff0c\u5e76\u5c06\u80ba\u90e8\u5de8\u566c\u7ec6\u80de\uff08\u53e6\u4e00\u7c7b\u514d\u75ab\u7ec6\u80de\uff09\u4ece\u4fc3\u708e\u72b6\u6001\u8f6c\u5411\u7ec4\u7ec7\u4fee\u590d\u72b6\u6001\u3002<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-\u51cf\u5c11\u55dc\u9178\u6027\u6c14\u9053\u708e\u75c7-39\">\u51cf\u5c11\u55dc\u9178\u6027\u6c14\u9053\u708e\u75c7<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u55dc\u9178\u6027\u7c92\u7ec6\u80de\u5728Type 2 high\u91cd\u75c7\u54ee\u5598\u7684\u6c14\u9053\u4e2d\u79ef\u7d2f\u5e76\u91ca\u653e\u7834\u574f\u7ec4\u7ec7\u7684\u86cb\u767d\u3002\u5b83\u4eec\u4f4d\u4e8eTh2\u4e0eILC2\u901a\u8def\u7684\u4e0b\u6e38\u2014\u2014\u4e0a\u6e38\u7ec6\u80de\u88abMSC\u5b89\u9759\u4e0b\u6765\u540e\uff0c\u53ec\u96c6\u55dc\u9178\u6027\u7c92\u7ec6\u80de\u5230\u6c14\u9053\u7684\u4fe1\u53f7\u672c\u8eab\u4e5f\u968f\u4e4b\u51cf\u5c11\u3002\u4e34\u5e8a\u524d\u6570\u636e\u5728\u591a\u4e2a\u6a21\u578b\u548c\u5b9e\u9a8c\u7cfb\u7edf\u4e2d\u4e00\u81f4\u663e\u793a\uff1aMSC\u6cbb\u7597\u53ef\u663e\u8457\u964d\u4f4e\u6c14\u9053\u55dc\u9178\u6027\u7c92\u7ec6\u80de\u8ba1\u6570\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8fd9\u4e0e\u6297IL-5\u751f\u7269\u5236\u5242\u7684\u4f5c\u7528\u673a\u5236\u7ed3\u6784\u4e0d\u540c\u3002\u7f8e\u6cca\u5229\u5355\u6297\u4e0e\u96f7\u5229\u73e0\u5355\u6297\u7ed3\u5408\u5e76\u4e2d\u548c\u5faa\u73af\u4e2d\u7684IL-5\uff1b\u8d1d\u90a3\u5229\u73e0\u5355\u6297\u901a\u8fc7\u6297\u4f53\u4f9d\u8d56\u6027\u7ec6\u80de\u6bd2\u6027\u76f4\u63a5\u6e05\u9664\u55dc\u9178\u6027\u7c92\u7ec6\u80de\u3002MSC\u65e2\u4e0d\u505a\u524d\u8005\uff0c\u4e5f\u4e0d\u505a\u540e\u8005\uff0c\u800c\u662f&#8221;\u51cf\u5c11\u53ec\u5524\u55dc\u9178\u6027\u7c92\u7ec6\u80de\u7684\u9700\u6c42\u672c\u8eab&#8221;\u3002\u8fd9\u79cd\u5dee\u5f02\u662f\u5426\u5e26\u6765\u66f4\u597d\u7684\u957f\u671f\u4e34\u5e8a\u6548\u679c\uff0c\u8fd8\u9700\u8981\u66f4\u5927\u89c4\u6a21\u7684\u4e34\u5e8a\u8bd5\u9a8c\u6765\u56de\u7b54\u3002<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-\u51cf\u7f13\u6c14\u9053\u91cd\u5851-42\">\u51cf\u7f13\u6c14\u9053\u91cd\u5851<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u7b2c\u4e09\u4e2a\u4f5c\u7528\u4e0e\u957f\u671f\u75be\u75c5\u8f68\u8ff9\u5173\u7cfb\u6700\u5bc6\u5207\u3002\u6c14\u9053\u91cd\u5851\u2014\u2014\u5e73\u6ed1\u808c\u3001\u57fa\u5e95\u819c\u4e0e\u80f6\u539f\u5c42\u7684\u7ed3\u6784\u6027\u589e\u539a\u2014\u2014\u662f\u7531\u6301\u7eed\u708e\u75c7\u73af\u5883\u9a71\u52a8\u7684\u3002\u5982\u679c\u708e\u75c7\u73af\u5883\u5f97\u5230\u6301\u7eed\u5e73\u606f\uff0c\u9a71\u52a8\u91cd\u5851\u7684\u751f\u7269\u4fe1\u53f7\u4e5f\u4f1a\u51cf\u5c11\u3002\u4e34\u5e8a\u524d\u7814\u7a76\u8868\u660eMSC\u6cbb\u7597\u53ef\u51cf\u8f7b\u6162\u6027\u54ee\u5598\u6a21\u578b\u4e2d\u7684\u6c14\u9053\u91cd\u5851\u6539\u53d8\uff0c\u4f46\u8fd9\u4e00\u6548\u5e94\u80fd\u5426\u5728\u4eba\u7c7b\u8eab\u4e0a\u4ee5\u4f55\u79cd\u65f6\u95f4\u5c3a\u5ea6\u5448\u73b0\uff0c\u4ecd\u662f\u6d3b\u8dc3\u7814\u7a76\u4e2d\u7684\u95ee\u9898\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u540c\u6837\u7684\u514d\u75ab\u8c03\u8282\u673a\u5236\u4e5f\u5728\u5176\u4ed6\u6162\u6027\u708e\u75c7\u6027\u75be\u75c5\u4e2d\u53d1\u6325\u4f5c\u7528\u2014\u2014\u6b63\u5728\u8003\u8651\u7c7b\u98ce\u6e7f\u5173\u8282\u708e\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u60a3\u8005\u8868\u73b0\u51fa\u76f8\u8fd1\u7684\u53cd\u5e94\u6a21\u5f0f\u3002Th2\u9a71\u52a8\u578b\u54ee\u5598\u4e0eTh17\u503e\u5411\u578b\u81ea\u8eab\u514d\u75ab\u75c5\u4e4b\u95f4\u7684\u673a\u5236\u91cd\u53e0\uff0c\u5df2\u7ecf\u6210\u4e3a\u6211\u4eec\u5224\u65ad\u54ea\u7c7b\u60a3\u8005\u66f4\u53ef\u80fd\u53d7\u76ca\u7684\u53c2\u8003\u4e4b\u4e00\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-\u91cd\u75c7\u54ee\u5598\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u4e34\u5e8a\u4e0e\u4e34\u5e8a\u524d\u8bc1\u636e-45\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u91cd\u75c7\u54ee\u5598\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u4e34\u5e8a\u4e0e\u4e34\u5e8a\u524d\u8bc1\u636e<\/mark><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-\u5f3a\u4e34\u5e8a\u524d\u4e34\u5e8a\u5c1a\u5904\u65e9\u671f\u9636\u6bb5-46\">\u5f3a\u4e34\u5e8a\u524d\u3001\u4e34\u5e8a\u5c1a\u5904\u65e9\u671f\u9636\u6bb5<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u6211\u4eec\u60f3\u5766\u8bda\u8bf4\u660e\u91cd\u75c7\u54ee\u5598\u5e72\u7ec6\u80de\u6cbb\u7597\u76ee\u524d\u7684\u8bc1\u636e\u6240\u5904\u7684\u9636\u6bb5\uff0c\u56e0\u4e3a\u8fd9\u662f\u60a3\u8005\u5728\u4efb\u4f55\u6cbb\u7597\u8ba8\u8bba\u4e4b\u524d\u90fd\u5e94\u5f53\u4e86\u89e3\u7684\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e34\u5e8a\u524d\u8bc1\u636e\u2014\u2014\u52a8\u7269\u5b9e\u9a8c\u4e0e\u4f53\u5916\u4eba\u6e90\u7ec6\u80de\u5b9e\u9a8c\u2014\u2014\u5df2\u7ecf\u76f8\u5f53\u5145\u5b9e\u3002\u591a\u4e2a\u7814\u7a76\u56e2\u961f\u5728\u8fc7\u654f\u539f\u8bf1\u5bfc\u548c\u5c18\u87a8\u8bf1\u5bfc\u7684\u91cd\u75c7\u54ee\u5598\u5c0f\u9f20\u6a21\u578b\u4e2d\uff0c\u8bc1\u5b9e\u6765\u6e90\u4e8e\u8110\u5e26\u3001\u9aa8\u9ad3\u3001\u8102\u80aa\u7ec4\u7ec7\u7684MSC\u90fd\u80fd\u51cf\u8f7b\u6c14\u9053\u708e\u75c7\u3001\u964d\u4f4e\u55dc\u9178\u6027\u7c92\u7ec6\u80de\u8ba1\u6570\u3001\u6291\u5236Th2\u548cILC2\u6d3b\u6027\uff0c\u5e76\u51cf\u5f31\u6c14\u9053\u9ad8\u53cd\u5e94\u6027\u3002\u673a\u5236\u8bc1\u636e\u53ef\u91cd\u590d\uff0c\u4e14\u89e3\u6790\u8d8a\u6765\u8d8a\u6e05\u6670\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4eba\u4f53\u4e34\u5e8a\u8bc1\u636e\u5219\u6bd4\u819d\u9aa8\u5173\u8282\u708e\u3001\u5fc3\u529b\u8870\u7aed\u7b49\u5176\u4ed6\u518d\u751f\u533b\u5b66\u5e94\u7528\u9886\u57df\u5904\u4e8e\u66f4\u65e9\u671f\u7684\u9636\u6bb5\u3002\u622a\u81f32026\u5e74\uff0c\u91cd\u75c7\u54ee\u5598\u5e72\u7ec6\u80de\u6cbb\u7597\u5c1a\u672a\u6709\u5927\u578bIII\u671f\u968f\u673a\u5bf9\u7167\u8bd5\u9a8c\u7684\u516c\u5f00\u53d1\u8868\u3002\u76ee\u524d\u5b58\u5728\u7684\u662f\u5c11\u91cfPhase 1\u4e0e\u65e9\u671fPhase 2\u8bd5\u9a8c\u3001\u82e5\u5e72\u75c5\u4f8b\u62a5\u544a\uff0c\u4ee5\u53ca\u5728\u56fd\u9645\u4e0a\u5f00\u5c55\u8be5\u6cbb\u7597\u7684\u533b\u7597\u673a\u6784\u79ef\u7d2f\u7684\u771f\u5b9e\u4e16\u754c\u4e34\u5e8a\u7ecf\u9a8c\u3002\u8003\u8651\u8be5\u6cbb\u7597\u7684\u60a3\u8005\uff0c\u5e94\u5f53\u5728\u4efb\u4f55\u8ba8\u8bba\u5f00\u59cb\u4e4b\u524d\uff0c\u628a\u8fd9\u4e2a\u80cc\u666f\u653e\u5728\u5fc3\u4e0a\u3002<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-\u5df2\u6ce8\u518c\u7684\u4e34\u5e8a\u8bd5\u9a8c\u4e0e\u65e9\u671f\u53d1\u73b0-50\">\u5df2\u6ce8\u518c\u7684\u4e34\u5e8a\u8bd5\u9a8c\u4e0e\u65e9\u671f\u53d1\u73b0<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u6700\u76f8\u5173\u7684\u3001\u76ee\u524d\u6b63\u5728\u8fdb\u884c\u6216\u8fd1\u671f\u5b8c\u6210\u7684\u8bd5\u9a8c\u5305\u62ec\u4ee5\u4e0b\u51e0\u9879\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7531The Foundation for Orthopaedics and Regenerative Medicine\u5f00\u5c55\u7684NCT05147688\u662f\u4e00\u98791\u671f\u8bd5\u9a8c\uff0c\u7814\u7a76\u4ed6\u6e90\u8110\u5e26\u6210\u4eba\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u9759\u8109\u8f93\u6ce8\u5728\u80ba\u90e8\u75be\u75c5\uff08\u5305\u62ec\u54ee\u5598\u4e0e\u6162\u6027\u963b\u585e\u6027\u80ba\u75be\u75c5\uff09\u4e2d\u7684\u5b89\u5168\u6027\u4e0e\u7597\u6548\u3002\u603b\u5242\u91cf\u7ea6\u4e3a\u5355\u6b211\u4ebf\u7ec6\u80de\uff0c\u968f\u8bbf\u65f6\u95f4\u4e3a1\u30016\u300112\u300124\u300136\u300148\u4e2a\u6708\u3002\u9996\u4f4d\u5165\u7ec4\u7684\u54ee\u5598\u53d7\u8bd5\u8005\u521d\u6b65\u7ed3\u679c\u7531Sharan\u7b49\u4eba\u4e8e2023\u5e74\u62a5\u544a\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u8fd9\u4f4d68\u5c81\u7537\u6027\u53d7\u8bd5\u8005\u5728\u6cbb\u7597\u540e2\u4e2a\u6708\u548c6\u4e2a\u6708\u7684\u968f\u8bbf\u4e2d\uff0c\u6025\u6551\u5438\u5165\u5668\u4f7f\u7528\u9891\u7387\u663e\u8457\u4e0b\u964d\uff0c\u672a\u89c2\u5bdf\u5230\u6cbb\u7597\u76f8\u5173\u4e0d\u826f\u4e8b\u4ef6\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7531\u57c3\u9ed8\u91cc\u5927\u5b66\u5f00\u5c55\u7684NCT05035862\u662f\u4e00\u9879\u5173\u4e8e\u5e72\u6270\u7d20-\u03b3\u5904\u7406MSC\u6cbb\u7597\u4e2d\u91cd\u5ea6\u6301\u7eed\u6027\u54ee\u5598\u76841\u671f\u8bd5\u9a8c\uff0c\u5242\u91cf\u4e3a200\u4e07\u6216500\u4e07\u7ec6\u80de\/\u516c\u65a4\u9759\u8109\u8f93\u6ce8\u3002\u8be5\u7814\u7a76\u56e0\u7ecf\u8d39\u539f\u56e0\u63d0\u524d\u7ed3\u675f\uff0c\u4f46\u5728\u7ec8\u6b62\u524d\u5165\u7ec4\u53d7\u8bd5\u8005\u7684\u5b89\u5168\u6027\u6570\u636e\uff0c\u4ecd\u5bf9MSC\u8f93\u6ce8\u5728\u8be5\u4eba\u7fa4\u4e2d\u7684\u8010\u53d7\u6027\u8ba4\u8bc6\u6709\u6240\u8d21\u732e\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">NCT02192736\u662f\u4e00\u9879\u65e9\u671f1\/2\u671f\u8bd5\u9a8c\uff0c\u4f7f\u7528\u8110\u5e26MSC\u5206\u6ccc\u7684\u4fe1\u53f7\u5206\u5b50\uff08\u8425\u517b\u56e0\u5b50\uff09\u7ecf\u9f3b\u7ed9\u836f\uff0c\u6cbb\u759720\u540d\u54ee\u5598\u60a3\u8005\uff0c\u4e3b\u8981\u7ec8\u70b9\u662f\u5b89\u5168\u6027\uff0c\u6b21\u8981\u7ec8\u70b9\u662f\u80ba\u529f\u80fd\u4e0e\u751f\u6d3b\u8d28\u91cf\u3002<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-\u73b0\u5b9e\u7684\u7597\u6548\u9884\u671f-55\">\u73b0\u5b9e\u7684\u7597\u6548\u9884\u671f<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u6211\u4eec\u60f3\u7ed9\u51fa\u73b0\u5b9e\u7684\u6570\u5b57\uff0c\u800c\u4e0d\u662f\u8425\u9500\u5f0f\u7684\u4e50\u89c2\u3002<\/p>\n\n\n\n<p 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id=\"aioseo-\u4e0d\u9002\u5408\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u60c5\u51b5-66\">\u4e0d\u9002\u5408\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u60c5\u51b5<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u5728\u4ee5\u4e0b\u4e34\u5e8a\u60c5\u51b5\u4e0b\uff0c\u6211\u4eec\u4f1a\u5efa\u8bae\u4e0d\u8fdb\u884c\u5e72\u7ec6\u80de\u6cbb\u7597\uff0c\u6216\u5766\u7387\u8bf4\u660e\u83b7\u76ca\u6982\u7387\u8f83\u4f4e\u3002<\/p>\n\n\n\n<p 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class=\"wp-block-paragraph\"><em>\u8fd9\u662f\u57fa\u4e8e\u5b9e\u9645\u4e34\u5e8a\u7ecf\u9a8c\u7684\u533f\u540d\u5316\u53d9\u8ff0\u3002\u4e2a\u4f53\u7ed3\u679c\u5dee\u5f02\u663e\u8457\uff0c\u8fd9\u4e00\u7ecf\u5386\u4e0d\u4ee3\u8868\u6240\u6709\u60a3\u8005\u4f1a\u83b7\u5f97\u7684\u7ed3\u679c\u3002<\/em><\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-the-treatment-process-for-severe-asthma-patients-in-malaysia-74\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u9a6c\u6765\u897f\u4e9a\u7684\u6cbb\u7597\u6d41\u7a0b<\/mark><\/h2>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"800\" height=\"436\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-Image-2-4.webp\" alt=\"\u65e5\u672c\u81ea\u4f53\u5e72\u7ec6\u80de\u6cbb\u7597\u4e0e\u9a6c\u6765\u897f\u4e9a\u4ed6\u6e90\u8110\u5e26MSC\u6cbb\u7597\u5bf9\u6bd4\u56fe\uff0c\u9488\u5bf9\u91cd\u75c7\u54ee\u5598\" class=\"wp-image-25064\" style=\"aspect-ratio:1.8348992638512205;width:641px;height:auto\" srcset=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-Image-2-4.webp 800w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-Image-2-4-300x164.webp 300w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-Image-2-4-768x419.webp 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption 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style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u91cd\u5ea6\u54ee\u5598\u5e72\u7ec6\u80de\u6cbb\u7597\u5e38\u89c1\u95ee\u9898\u89e3\u7b54<\/mark><\/h2>\n\n\n\n<div data-wp-context=\"{ &quot;autoclose&quot;: false, &quot;accordionItems&quot;: [] }\" data-wp-interactive=\"core\/accordion\" role=\"group\" class=\"wp-block-accordion is-layout-flow wp-block-accordion-is-layout-flow\">\n<div data-wp-class--is-open=\"state.isOpen\" data-wp-context=\"{ &quot;id&quot;: &quot;accordion-item-1&quot;, &quot;openByDefault&quot;: false }\" data-wp-init=\"callbacks.initAccordionItems\" data-wp-on-window--hashchange=\"callbacks.hashChange\" class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h4 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-1-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" id=\"accordion-item-1\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span class=\"wp-block-accordion-heading__toggle-title\"><strong>\u63a5\u53d7\u91cd\u75c7\u54ee\u5598\u5e72\u7ec6\u80de\u6cbb\u7597\u524d\u9700\u8981\u505c\u6389\u73b0\u7528\u836f\u7269\u5417\uff1f<\/strong><\/span><span class=\"wp-block-accordion-heading__toggle-icon\" aria-hidden=\"true\">+<\/span><\/button><\/h4>\n\n\n\n<div aria-labelledby=\"accordion-item-1\" data-wp-bind--hidden=\"state.isHidden\" data-wp-on--beforematch=\"actions.handleBeforeMatch\" id=\"accordion-item-1-panel\" role=\"region\" class=\"wp-block-accordion-panel is-layout-flow wp-block-accordion-panel-is-layout-flow\">\n<p 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data-wp-class--is-open=\"state.isOpen\" data-wp-context=\"{ &quot;id&quot;: &quot;accordion-item-2&quot;, &quot;openByDefault&quot;: false }\" data-wp-init=\"callbacks.initAccordionItems\" data-wp-on-window--hashchange=\"callbacks.hashChange\" class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h4 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-2-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" id=\"accordion-item-2\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span class=\"wp-block-accordion-heading__toggle-title\"><strong>\u6cbb\u7597\u540e\u591a\u4e45\u80fd\u770b\u5230\u6548\u679c\uff1f<\/strong><\/span><span class=\"wp-block-accordion-heading__toggle-icon\" aria-hidden=\"true\">+<\/span><\/button><\/h4>\n\n\n\n<div aria-labelledby=\"accordion-item-2\" data-wp-bind--hidden=\"state.isHidden\" data-wp-on--beforematch=\"actions.handleBeforeMatch\" id=\"accordion-item-2-panel\" role=\"region\" class=\"wp-block-accordion-panel is-layout-flow wp-block-accordion-panel-is-layout-flow\">\n<p 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class=\"wp-block-accordion is-layout-flow wp-block-accordion-is-layout-flow\">\n<div data-wp-class--is-open=\"state.isOpen\" data-wp-context=\"{ &quot;id&quot;: &quot;accordion-item-3&quot;, &quot;openByDefault&quot;: false }\" data-wp-init=\"callbacks.initAccordionItems\" data-wp-on-window--hashchange=\"callbacks.hashChange\" class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h4 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-3-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" id=\"accordion-item-3\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span class=\"wp-block-accordion-heading__toggle-title\"><strong>\u91cd\u75c7\u54ee\u5598\u5e72\u7ec6\u80de\u6cbb\u7597\u80fd\u66ff\u4ee3\u751f\u7269\u5236\u5242\u5417\uff1f<\/strong><\/span><span class=\"wp-block-accordion-heading__toggle-icon\" aria-hidden=\"true\">+<\/span><\/button><\/h4>\n\n\n\n<div aria-labelledby=\"accordion-item-3\" data-wp-bind--hidden=\"state.isHidden\" data-wp-on--beforematch=\"actions.handleBeforeMatch\" id=\"accordion-item-3-panel\" role=\"region\" class=\"wp-block-accordion-panel is-layout-flow wp-block-accordion-panel-is-layout-flow\">\n<p 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style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u53c2\u8003\u6587\u732e<\/mark><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>GBD 2021 Asthma Collaborators. &#8220;Global, regional, national burden of asthma from 1990 to 2021, with projections of incidence to 2050: a systematic analysis of the global burden of disease study 2021.&#8221; eClinicalMedicine. 2024. <a href=\"https:\/\/doi.org\/10.1016\/j.eclinm.2024.102921\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1016\/j.eclinm.2024.102921<\/a><\/li>\n\n\n\n<li>Shin JW, Ryu S, Ham J, Jung K, Lee S, Chung DH, Kang HR, Kim HY. &#8220;Mesenchymal Stem Cells Suppress Severe Asthma by Directly Regulating Th2 Cells and Type 2 Innate Lymphoid Cells.&#8221; Molecules and Cells. 2021;44(8):580\u2013590. <a href=\"https:\/\/doi.org\/10.14348\/molcells.2021.0101\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.14348\/molcells.2021.0101<\/a><\/li>\n\n\n\n<li>Sharan J, et al. &#8220;Safety of cultured allogeneic adult umbilical cord-derived mesenchymal stem cell intravenous infusion for the treatment of pulmonary diseases: Preliminary findings (NCT05147688).&#8221; 2023. ClinicalTrials.gov: <a href=\"https:\/\/clinicaltrials.gov\/study\/NCT05147688\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/clinicaltrials.gov\/study\/NCT05147688<\/a><\/li>\n\n\n\n<li>ClinicalTrials.gov NCT05035862. &#8220;A Phase 1 Study to Evaluate Safety, Toxicity, and Potential Mechanisms of Interferon Gamma-primed Mesenchymal Stromal Cells (MSCs) for Moderate-to-severe Persistent Asthma.&#8221; Emory University. <a href=\"https:\/\/clinicaltrials.gov\/study\/NCT05035862\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/clinicaltrials.gov\/study\/NCT05035862<\/a><\/li>\n\n\n\n<li>Wang LT, Liu KJ, Sytwu HK, Yen ML, Yen BL. &#8220;Advances in mesenchymal stem cell therapy for immune and inflammatory diseases: Use of cell-free products and human pluripotent stem cell-derived mesenchymal stem cells.&#8221; Stem Cells Translational Medicine. 2021;10(9):1288\u20131303. <a href=\"https:\/\/doi.org\/10.1002\/sctm.21-0021\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1002\/sctm.21-0021<\/a><\/li>\n\n\n\n<li>Wang YH, Tsai DY, Ko YA, Yang TT, Lin IY, Hung KH, Lin KI. &#8220;Mesenchymal Stem\/Stromal Cells in Asthma Therapy: Mechanisms and Strategies for Enhancement.&#8221; Cell Transplantation. 2023. <a href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10278440\/\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10278440\/<\/a><\/li>\n\n\n\n<li>Bagnasco D, Caminati M, Menzella F, Milanese M, Rolla G, Lombardi C, Bucca C, Heffler E, Paoletti G, Testino E, et al. &#8220;One year of mepolizumab. Efficacy and safety in real-life in Italy.&#8221; Pulmonary Pharmacology &amp; Therapeutics. 2019;58:101836. <a href=\"https:\/\/doi.org\/10.1016\/j.pupt.2019.101836\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1016\/j.pupt.2019.101836<\/a><\/li>\n\n\n\n<li>Volpato M, Vianello A, Antonicelli L, Bagnasco D, Caminati M, Canonica GW, et al. &#8220;Oral Corticosteroids Dependence and Biologic Drugs in Severe Asthma: Myths or Facts? A Systematic Review of Real-World Evidence.&#8221; International Journal of Molecular Sciences. 2021;22(13):7132. <a href=\"https:\/\/doi.org\/10.3390\/ijms22137132\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.3390\/ijms22137132<\/a><\/li>\n\n\n\n<li>Chung KF, Wenzel SE, Brozek JL, Bush A, Castro M, Sterk PJ, et al. &#8220;International ERS\/ATS guidelines on definition, evaluation and treatment of severe asthma.&#8221; European Respiratory Journal. 2014;43:343\u2013373. <a href=\"https:\/\/doi.org\/10.1183\/09031936.00202013\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1183\/09031936.00202013<\/a><\/li>\n\n\n\n<li>Song N, Scholtemeijer M, Shah K. &#8220;Mesenchymal Stem Cell Immunomodulation: Mechanisms and Therapeutic Potential.&#8221; Trends in Pharmacological Sciences. 2020;41(9):653\u2013664. <a href=\"https:\/\/doi.org\/10.1016\/j.tips.2020.06.009\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1016\/j.tips.2020.06.009<\/a><\/li>\n<\/ol>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\t\t<div data-elementor-type=\"section\" data-elementor-id=\"21876\" class=\"elementor elementor-21876\" data-elementor-post-type=\"elementor_library\">\n\t\t\t        <section class=\"elementor-section elementor-top-section elementor-element elementor-element-a6ebaad elementor-section-boxed elementor-section-height-default elementor-section-height-default pxl-row-scroll-none pxl-zoom-point-false pxl-section-overflow-visible pxl-section-fix-none pxl-bg-color-none pxl-section-overlay-none\" data-id=\"a6ebaad\" data-element_type=\"section\" data-e-type=\"section\">\n\n                \n                <div class=\"elementor-container elementor-column-gap-default \">\n                <div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-d089a17 pxl-column-none pxl-column-overflow-hidden-no\" data-id=\"d089a17\" data-element_type=\"column\" data-e-type=\"column\">\r\n        <div class=\"elementor-widget-wrap\">\r\n                     \r\n                    <\/div>\r\n        <\/div>\r\n        \t\t\t<\/div>\n\t\t<\/section>\n\t\t        <section class=\"elementor-section elementor-top-section elementor-element elementor-element-4e5fd18 elementor-section-boxed elementor-section-height-default elementor-section-height-default pxl-row-scroll-none pxl-zoom-point-false pxl-section-overflow-visible pxl-section-fix-none pxl-bg-color-none pxl-section-overlay-none\" data-id=\"4e5fd18\" data-element_type=\"section\" data-e-type=\"section\">\n\n                \n                <div class=\"elementor-container elementor-column-gap-default \">\n                <div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-ab6d30b pxl-column-none pxl-column-overflow-hidden-no\" data-id=\"ab6d30b\" data-element_type=\"column\" data-e-type=\"column\">\r\n        <div class=\"elementor-widget-wrap elementor-element-populated\">\r\n                     \r\n        \t\t<div class=\"elementor-element elementor-element-7f730e7 elementor-widget elementor-widget-text-editor\" data-id=\"7f730e7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p data-start=\"0\" data-end=\"14\">\u2139 Disclaimer<br \/>The information provided on this website (including but not limited to stem cell therapy, exosome therapy, regenerative medicine, clinical research, and pricing information) is intended solely for general informational and educational purposes and does not constitute medical advice, diagnosis, treatment recommendations, or legal advice.<\/p><p data-start=\"1359\" data-end=\"1629\">The field of regenerative medicine evolves rapidly in terms of regulatory frameworks and research developments; therefore, the completeness, accuracy, or current validity of the information presented cannot be guaranteed. Treatment outcomes may vary between individuals.\u00a0 Before making any medical decisions, you should consult a qualified healthcare professional and independently verify the applicable regulatory status in your respective country.<\/p><p data-start=\"1810\" data-end=\"1921\" data-is-last-node=\"\" data-is-only-node=\"\">The company assumes no liability for any damages arising from the use of information contained on this website.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t            <\/div>\r\n        <\/div>\r\n        \t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t\n","protected":false},"excerpt":{"rendered":"<p>\u91cd\u75c7\u54ee\u5598\u7684\u5e72\u7ec6\u80de\u6cbb\u7597\uff5c\u4e0d\u52a0\u91cd\u6fc0\u7d20\u4e5f\u80fd\u7f13\u89e3\u6c14\u9053\u708e\u75c7\u5417 \u722c\u5230\u7b2c\u4e8c\u5c42\u697c\u68af\u5c31\u8981\u5728\u4e2d\u95f4\u505c\u4e00\u4e0b\uff0c\u5df2\u7ecf\u6210\u4e86\u4e0d\u9700\u8981\u601d\u8003\u7684\u53cd\u5e94\u3002 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