{"id":24298,"date":"2026-04-13T14:34:42","date_gmt":"2026-04-13T06:34:42","guid":{"rendered":"https:\/\/stemcell-malaysia.com\/?page_id=24298"},"modified":"2026-04-15T09:42:47","modified_gmt":"2026-04-15T01:42:47","slug":"aging-frailty","status":"publish","type":"page","link":"https:\/\/stemcell-malaysia.com\/zh\/conditions\/aging-frailty\/","title":{"rendered":"\u8001\u5e74\u8870\u5f31\u7efc\u5408\u5f81\u5e72\u7ec6\u80de\u6cbb\u7597\uff5c\u5f53\u8fd0\u52a8\u548c\u8425\u517b\u90fd\u65e0\u6cd5\u963b\u6b62\u4f53\u529b\u8870\u9000\u65f6"},"content":{"rendered":"\n<h1 class=\"wp-block-heading has-text-align-center\">\u8001\u5e74\u8870\u5f31\u7efc\u5408\u5f81\u5e72\u7ec6\u80de\u6cbb\u7597\uff5c\u5f53\u8fd0\u52a8\u548c\u8425\u517b\u90fd\u65e0\u6cd5\u963b\u6b62\u4f53\u529b\u8870\u9000\u65f6<\/h1>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"533\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/pexels-busranur-aydin-3800407-17408384.webp\" alt=\"\u7279\u5199\u955c\u5934\uff0c\u4ece\u4e0a\u5f80\u4e0b\u62cd\u6444\uff0c\u4e00\u53ea\u5e74\u8f7b\u4eba\u7684\u624b\u8f7b\u8f7b\u5730\u6367\u7740\u5e76\u6258\u7740\u4e00\u4f4d\u8001\u4eba\u9971\u7ecf\u98ce\u971c\u3001\u5e03\u6ee1\u76b1\u7eb9\u7684\u624b\u3002\" class=\"wp-image-24256\" style=\"width:592px\" srcset=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/pexels-busranur-aydin-3800407-17408384.webp 800w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/pexels-busranur-aydin-3800407-17408384-300x200.webp 300w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/pexels-busranur-aydin-3800407-17408384-768x512.webp 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption 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\u4e0b\u5348\u6ca1\u505a\u4ec0\u4e48\u4e8b\uff0c\u5374\u5df2\u7ecf\u6ca1\u4e86\u529b\u6c14\u3002 \u7761\u4e86\u516b\u4e2a\u5c0f\u65f6\uff0c\u7b2c\u4e8c\u5929\u8d77\u6765\u4f9d\u7136\u89c9\u5f97\u6ca1\u7761\u591f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6bcf\u6b21\u542c\u5230&#8221;\u5e74\u7eaa\u5927\u4e86\u5c31\u662f\u8fd9\u6837&#8221;\u8fd9\u53e5\u8bdd\uff0c\u5fc3\u91cc\u603b\u6709\u4e00\u4e2a\u5ff5\u5934\u6ca1\u6709\u6d88\u6563\u2014\u2014 \u771f\u7684\u53ea\u662f\u5e74\u7eaa\u7684\u95ee\u9898\u5417\uff1f<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8001\u5e74\u8870\u5f31\u7efc\u5408\u5f81\uff08\u82f1\u6587\uff1aFrailty Syndrome\uff09\u4e0d\u662f\u666e\u901a\u7684\u8001\u5316\u73b0\u8c61\u3002 \u5b83\u662f\u4e00\u79cd\u6709\u4e34\u5e8a\u8bca\u65ad\u6807\u51c6\u7684\u7efc\u5408\u5f81\uff1a\u975e\u523b\u610f\u4f53\u91cd\u4e0b\u964d\u3001\u529b\u91cf\u51cf\u9000\u3001\u75b2\u52b3\u611f\u3001\u6b65\u901f\u51cf\u6162\u3001\u6d3b\u52a8\u91cf\u4e0b\u964d\uff0c\u8fd9\u4e94\u9879\u4e2d\u7b26\u5408\u4e09\u9879\u4ee5\u4e0a\uff0c\u5c31\u8fbe\u5230\u8870\u5f31\u7684\u8bca\u65ad\u6807\u51c6\u3002 \u4e2d\u56fd65\u5c81\u4ee5\u4e0a\u793e\u533a\u8001\u5e74\u4eba\u4e2d\uff0c\u7ea6\u670910%~12%\u7b26\u5408\u8fd9\u4e00\u6807\u51c6\uff0c\u4f30\u8ba1\u8d85\u8fc72000\u4e07\u4eba\u3002\u52a0\u4e0a\u5904\u4e8e&#8221;\u524d\u8870\u5f31&#8221;\u9636\u6bb5\u7684\u4eba\uff0c\u6570\u91cf\u8d85\u8fc7\u4ebf\u7ea7\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u800c\u5927\u591a\u6570\u4eba\u4ece\u533b\u9662\u5f97\u5230\u7684\u56de\u7b54\u53ea\u6709\u4e00\u4e2a\uff1a\u591a\u8fd0\u52a8\uff0c\u591a\u8865\u86cb\u767d\u8d28\u3002<\/p>\n\n\n\n<p 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class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u76ee\u5f55<\/mark><\/h2>\n\n\n<div class=\"wp-block-aioseo-table-of-contents\"><ol><li><a class=\"aioseo-toc-item\" href=\"#aioseo-why-aging-frailty-cannot-be-reversed-by-rest-and-willpower-alone-13\">\u8001\u5e74\u8870\u5f31\u7efc\u5408\u5f81\u4e3a\u4f55\u9760\u8fd0\u52a8\u65e0\u6cd5\u5f7b\u5e95\u9006\u8f6c\uff1a\u7ec6\u80de\u5c42\u9762\u7684\u539f\u56e0<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-what-conventional-frailty-management-gets-right-and-where-it-stops-short-28\">\u4f20\u7edf\u8870\u5f31\u5e72\u9884\u5230\u4e86\u5929\u82b1\u677f\u4e4b\u540e<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-three-biological-mechanisms-behind-stem-cell-therapy-for-aging-frailty-40\">\u5e72\u7ec6\u80de\u6cbb\u7597\u5bf9\u8870\u5f31\u7efc\u5408\u5f81\u7684\u4e09\u79cd\u4f5c\u7528\u673a\u5236<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-what-the-clinical-trial-data-shows-for-msc-therapy-and-frailty-related-outcomes-54\">\u4e34\u5e8a\u6570\u636e\u8bf4\u660e\u4e86\u4ec0\u4e48\u2014\u2014\u5177\u4f53\u6570\u5b57\u4e0e\u771f\u5b9e\u610f\u4e49<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-who-is-and-is-not-a-suitable-candidate-for-stem-cell-therapy-for-aging-frailty-74\">\u54ea\u4e9b\u4eba\u9002\u5408\u3001\u54ea\u4e9b\u4eba\u4e0d\u9002\u5408\u5e72\u7ec6\u80de\u6cbb\u7597<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-a-patients-account-what-recovery-from-aging-frailty-looked-like-over-six-months-88\">\u60a3\u8005\u81ea\u8ff0\uff1a\u516d\u4e2a\u6708\u95f4\u8870\u8001\u8870\u5f31\u75c7\u5eb7\u590d\u7684\u771f\u5b9e\u5386\u7a0b<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-honest-risks-and-limitations-of-stem-cell-therapy-for-aging-frailty-103\">\u8001\u5e74\u8870\u5f31\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u98ce\u9669\u4e0e\u8bda\u5b9e\u7684\u5c40\u9650<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#tw-target-text\">\u5173\u4e8e\u8870\u8001\u3001\u865a\u5f31\u548c\u5e72\u7ec6\u80de\u7597\u6cd5\u7684\u5e38\u89c1\u95ee\u9898<\/a><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-if-you-are-looking-for-more-than-a-plateau-144\">\u7ed9\u90a3\u4e9b\u4e0d\u7518\u5fc3\u7ee7\u7eed\u4e0b\u6ed1\u7684\u4eba<\/a><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-references-148\">\u53c2\u8003\u6587\u732e<\/a><\/li><\/ol><\/div>\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-why-aging-frailty-cannot-be-reversed-by-rest-and-willpower-alone-13\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u8001\u5e74\u8870\u5f31\u7efc\u5408\u5f81\u4e3a\u4f55\u9760\u8fd0\u52a8\u65e0\u6cd5\u5f7b\u5e95\u9006\u8f6c\uff1a\u7ec6\u80de\u5c42\u9762\u7684\u539f\u56e0<\/mark><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-the-biology-behind-frailty-it-starts-long-before-the-symptoms-14\">\u6162\u6027\u708e\u75c7\uff08\u708e\u6027\u8870\u8001\uff09\u5982\u4f55\u63a8\u52a8\u8870\u5f31\u7684\u8fdb\u5c55<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u8981\u7406\u89e3\u4e3a\u4ec0\u4e48\u540c\u6837\u7684\u8fd0\u52a8\u5728\u5e74\u8f7b\u65f6\u80fd\u7ec3\u51fa\u808c\u8089\uff0c\u5e74\u8001\u540e\u5374\u6548\u679c\u8d8a\u6765\u8d8a\u5dee\uff0c\u9700\u8981\u4ece\u7ec6\u80de\u5c42\u9762\u627e\u7b54\u6848\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5728\u5065\u5eb7\u72b6\u6001\u4e0b\uff0c\u708e\u75c7\u53cd\u5e94\u662f\u8eab\u4f53\u5bf9\u611f\u67d3\u6216\u635f\u4f24\u7684\u5e94\u6025\u53cd\u5e94\uff0c\u6108\u5408\u540e\u4fbf\u4f1a\u5e73\u606f\u3002 \u4f46\u5728\u8870\u5f31\u53d1\u5c55\u8fc7\u7a0b\u4e2d\uff0c\u8fd9\u4e2a&#8221;\u5173\u95ed\u5f00\u5173&#8221;\u53d8\u5f97\u8d8a\u6765\u8d8a\u4e0d\u7075\u654f\u3002 TNF-\u03b1\uff08\u80bf\u7624\u574f\u6b7b\u56e0\u5b50-\u03b1\uff09\u548c\u767d\u7ec6\u80de\u4ecb\u7d20-6\uff08IL-6\uff09\u7b49\u7ec6\u80de\u56e0\u5b50\uff08\u7ec6\u80de\u95f4\u901a\u4fe1\u86cb\u767d\uff09\u4ee5\u4f4e\u6c34\u5e73\u6301\u7eed\u5faa\u73af\u5728\u8840\u6db2\u4e2d\uff0c\u65e0\u6cd5\u5173\u95ed\u3002 \u7814\u7a76\u8005\u5c06\u8fd9\u79cd\u72b6\u6001\u79f0\u4e3a&#8221;\u708e\u6027\u8870\u8001&#8221;\uff08inflammaging\uff09\u3002<\/p>\n\n\n\n<p 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class=\"wp-block-paragraph\">\u8870\u5f31\u7684\u7b2c\u4e8c\u4e2a\u6838\u5fc3\u673a\u5236\u662f\u808c\u8089\u536b\u661f\u7ec6\u80de\uff08satellite cell\uff0c\u808c\u8089\u5e72\u7ec6\u80de\uff09\u7684\u529f\u80fd\u9000\u5316\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u536b\u661f\u7ec6\u80de\u7684\u804c\u8d23\u662f\u4fee\u590d\u8fd0\u52a8\u540e\u4ea7\u751f\u7684\u5fae\u635f\u4f24\uff0c\u4ece\u800c\u8ba9\u808c\u8089\u5728\u6062\u590d\u8fc7\u7a0b\u4e2d\u53d8\u5f97\u66f4\u5f3a\u3002 \u5728\u5e74\u8f7b\u65f6\uff0c\u8fd0\u52a8\u523a\u6fc0\u4e00\u6765\uff0c\u536b\u661f\u7ec6\u80de\u5c31\u8fc5\u901f\u6d3b\u5316\u3001\u589e\u6b96\u3001\u5b8c\u6210\u4fee\u590d\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5728\u8870\u5f31\u8001\u5e74\u4eba\u7684\u808c\u8089\u4e2d\uff0c\u536b\u661f\u7ec6\u80de\u6570\u91cf\u51cf\u5c11\uff0c\u5269\u4f59\u7684\u7ec6\u80de\u4e5f\u5927\u591a\u5904\u4e8e&#8221;\u4f11\u7720\u72b6\u6001&#8221;\uff0c\u5bf9\u8fd0\u52a8\u523a\u6fc0\u7684\u54cd\u5e94\u53d8\u5f97\u8fdf\u949d\u3002 \u540c\u6837\u7684\u8fd0\u52a8\u91cf\uff0c\u7ec6\u80de\u4fee\u590d\u7684\u57fa\u7840\u5df2\u7ecf\u9000\u5316\uff0c\u8f93\u51fa\u81ea\u7136\u51cf\u5c11\u3002 &#8220;\u62fc\u547d\u953b\u70bc\u5374\u6ca1\u6709\u6548\u679c&#8221;\u2014\u2014\u4e0d\u662f\u610f\u5fd7\u529b\u4e0d\u591f\uff0c\u800c\u662f\u7ec6\u80de\u57fa\u7840\u8bbe\u65bd\u51fa\u4e86\u95ee\u9898\u3002<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-mitochondrial-dysfunction-and-the-energy-deficit-in-aging-frailty-23\">\u7ebf\u7c92\u4f53\u529f\u80fd\u4e0b\u964d\u4e0e\u8870\u5f31\u6027\u75b2\u52b3<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u8870\u5f31\u60a3\u8005\u666e\u904d\u53cd\u6620\u7684&#8221;\u600e\u4e48\u7761\u90fd\u4e0d\u591f&#8221;\u7684\u75b2\u52b3\u611f\uff0c\u4e0e\u7ebf\u7c92\u4f53\u529f\u80fd\u4e0b\u964d\u5bc6\u5207\u76f8\u5173\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7ebf\u7c92\u4f53\u662f\u7ec6\u80de\u5185\u7684\u80fd\u91cf\u5de5\u5382\u3002 \u968f\u7740\u5e74\u9f84\u589e\u957f\uff0c\u635f\u4f24\u7d2f\u79ef\uff0c\u80fd\u91cf\u4ea7\u751f\u6548\u7387\u4e0b\u964d\uff0c\u540c\u65f6\u4ea7\u751f\u66f4\u591a\u6709\u5bb3\u7684\u6c27\u5316\u4ea7\u7269\u3002 \u8fd9\u79cd\u75b2\u52b3\u4e0d\u662f\u7761\u7720\u95ee\u9898\uff0c\u800c\u662f\u80fd\u91cf\u751f\u4ea7\u672c\u8eab\u7684\u95ee\u9898\u3002<\/p>\n\n\n\n<p 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id=\"aioseo-the-real-value-of-exercise-and-nutrition-for-aging-frailty-29\">\u8fd0\u52a8\u4e0e\u8425\u517b\u7684\u771f\u5b9e\u4ef7\u503c\uff0c\u4ee5\u53ca\u5b83\u7684\u8fb9\u754c<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u6297\u963b\u8fd0\u52a8\uff08\u529b\u91cf\u8bad\u7ec3\uff09\u548c\u86cb\u767d\u8d28\u8865\u5145\u662f\u8870\u5f31\u5e72\u9884\u4e2d\u8bc1\u636e\u6700\u5145\u5206\u7684\u65b9\u6cd5\uff0c\u8fd9\u4e00\u70b9\u6211\u4eec\u4e0d\u5426\u8ba4\u3002 \u5728\u9002\u5f53\u5b9e\u65bd\u7684\u60c5\u51b5\u4e0b\uff0c\u6b65\u901f\u3001\u63e1\u529b\u3001\u65e5\u5e38\u751f\u6d3b\u80fd\u529b\u5747\u6709\u7edf\u8ba1\u5b66\u663e\u8457\u6539\u5584\u7684\u62a5\u544a\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7136\u800c\uff0c&#8221;\u523a\u6fc0&#8221;\u80fd\u4ea7\u751f&#8221;\u53cd\u5e94&#8221;\u7684\u524d\u63d0\uff0c\u662f\u63a5\u53d7\u523a\u6fc0\u7684\u7ec6\u80de\u57fa\u7840\u5c1a\u4e14\u529f\u80fd\u6b63\u5e38\u3002 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class=\"wp-block-paragraph\">\u622a\u81f32026\u5e74\uff0c\u5168\u7403\u5c1a\u65e0\u4efb\u4f55\u76d1\u7ba1\u673a\u6784\u6279\u51c6\u7684\u4e13\u95e8\u9488\u5bf9\u8870\u5f31\u7efc\u5408\u5f81\u7684\u836f\u7269\u3002<br>\u7ef4\u751f\u7d20D\u8865\u5145\u5728\u964d\u4f4e\u9aa8\u6298\u98ce\u9669\u65b9\u9762\u6709\u4e00\u5b9a\u6839\u636e\uff0c\u4f46\u5bf9\u8870\u5f31\u7684\u529f\u80fd\u6027\u6539\u5584\u6548\u679c\u6709\u9650\u3002<br>\u8bb8\u591a\u8001\u5e74\u60a3\u8005\u5df2\u5728\u670d\u7528\u591a\u79cd\u836f\u7269\uff0c\u518d\u53e0\u52a0\u836f\u7269\u7684\u8d1f\u62c5\u4e5f\u662f\u73b0\u5b9e\u95ee\u9898\u3002<\/p>\n\n\n\n<div style=\"height:39px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-three-biological-mechanisms-behind-stem-cell-therapy-for-aging-frailty-40\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u5e72\u7ec6\u80de\u6cbb\u7597\u5bf9\u8870\u5f31\u7efc\u5408\u5f81\u7684\u4e09\u79cd\u4f5c\u7528\u673a\u5236<\/mark><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"775\" height=\"433\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/CH.webp\" alt=\"\u5c55\u793a\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSC\uff09\u6cbb\u7597\u8001\u5e74\u8870\u5f31\u7efc\u5408\u5f81\u7684\u4e09\u79cd\u4f5c\u7528\u673a\u5236\u7684\u793a\u610f\u56fe\u2014\u2014\u6291\u5236\u6162\u6027\u708e\u75c7\u3001\u6539\u5584\u808c\u8089\u536b\u661f\u7ec6\u80de\u73af\u5883\u3001\u652f\u6301\u7ebf\u7c92\u4f53\u529f\u80fd\" class=\"wp-image-24304\" style=\"width:592px\" srcset=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/CH.webp 775w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/CH-300x168.webp 300w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/CH-768x429.webp 768w\" sizes=\"(max-width: 775px) 100vw, 775px\" \/><figcaption class=\"wp-element-caption\">MSC\u4e0d\u4f1a\u76f4\u63a5\u53d8\u6210\u65b0\u7684\u808c\u8089\u7ec6\u80de\uff0c\u800c\u662f\u901a\u8fc7\u91ca\u653e\u4fe1\u53f7\u5206\u5b50\u6539\u53d8\u7ec6\u80de\u4fee\u590d\u73af\u5883\u3002<\/figcaption><\/figure>\n<\/div>\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-mechanism-1-reducing-the-chronic-inflammation-that-drives-aging-frailty-41\">\u673a\u5236\u4e00\uff1a\u6291\u5236\u9a71\u52a8\u8870\u5f31\u7684\u6162\u6027\u708e\u75c7<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSC\uff1aMesenchymal Stem Cell\uff09\u4e0d\u662f\u901a\u8fc7\u53d8\u6210\u65b0\u7684\u808c\u8089\u7ec6\u80de\u6765\u8d77\u6548\u7684\u3002 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class=\"wp-block-paragraph\">\u7c7b\u98ce\u6e7f\u5173\u8282\u708e\u7684\u5e72\u7ec6\u80de\u6cbb\u7597\u4e2d\u786e\u8ba4\u7684\u514d\u75ab\u8c03\u8282\u673a\u5236\uff0c\u4e0e\u8870\u5f31\u7efc\u5408\u5f81\u4e2d\u5168\u8eab\u6027\u708e\u75c7\u6291\u5236\u673a\u5236\u5171\u4eab\u76f8\u540c\u7684\u751f\u7269\u5b66\u57fa\u7840\u3002<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-mechanism-2-supporting-muscle-satellite-cell-function-in-aging-frailty-46\">\u673a\u5236\u4e8c\uff1a\u4e3a\u808c\u8089\u536b\u661f\u7ec6\u80de\u521b\u9020\u66f4\u597d\u7684\u5de5\u4f5c\u73af\u5883<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">MSC\u91ca\u653e\u7684\u751f\u957f\u56e0\u5b50\u548c\u4fe1\u53f7\u5206\u5b50\u53ef\u4ee5\u5f71\u54cd\u9aa8\u9abc\u808c\u5185\u536b\u661f\u7ec6\u80de\u7684\u529f\u80fd\u72b6\u6001\u3002 \u52a8\u7269\u6a21\u578b\u548c\u90e8\u5206\u4e34\u5e8a\u89c2\u5bdf\u663e\u793a\uff0cMSC\u53d1\u51fa\u7684\u4fe1\u53f7\u6709\u52a9\u4e8e\u8ba9\u5904\u4e8e\u4f11\u7720\u72b6\u6001\u7684\u536b\u661f\u7ec6\u80de\u66f4\u5bb9\u6613\u5207\u6362\u5230\u6d3b\u5316\u6a21\u5f0f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4f46\u9700\u8981\u660e\u786e\u7684\u662f\uff1aMSC\u4e0d\u4f1a\u53d8\u6210\u65b0\u7684\u536b\u661f\u7ec6\u80de\uff0c\u4e5f\u4e0d\u4f1a\u76f4\u63a5\u8865\u5145\u5df2\u7ecf\u5931\u53bb\u7684\u808c\u8089\u91cf\u3002 \u5b83\u7684\u4f5c\u7528\u66f4\u50cf\u662f&#8221;\u6539\u5584\u73b0\u6709\u4fee\u590d\u56e2\u961f\u7684\u5de5\u4f5c\u6761\u4ef6&#8221;\uff0c\u800c\u4e0d\u662f&#8221;\u62db\u52df\u65b0\u7684\u5de5\u4eba&#8221;\u3002 \u51e0\u5341\u5e74\u79ef\u7d2f\u7684\u808c\u8089\u635f\u5931\uff0c\u4e0d\u53ef\u80fd\u5728\u51e0\u4e2a\u6708\u5185\u5f97\u5230\u5168\u9762\u4fee\u590d\u2014\u2014\u8fd9\u4e00\u70b9\u9700\u8981\u6709\u73b0\u5b9e\u7684\u9884\u671f\u3002<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-mechanism-3-supporting-mitochondrial-function-and-cellular-energy-in-aging-frailty-50\">\u673a\u5236\u4e09\uff1a\u652f\u6301\u7ebf\u7c92\u4f53\u529f\u80fd\u7684\u53ef\u80fd\u6027<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u76ee\u524d\u7814\u7a76\u9636\u6bb5\u7684\u4e00\u4e2a\u503c\u5f97\u5173\u6ce8\u7684\u53d1\u73b0\u662f\uff0cMSC\u5206\u6ccc\u7684\u5916\u6ccc\u4f53\uff08\u7ec6\u80de\u91ca\u653e\u7684\u5fae\u578b\u4fe1\u606f\u4f20\u9012\u56ca\u6ce1\uff09\u4e2d\u542b\u6709\u7ebf\u7c92\u4f53\u76f8\u5173\u6210\u5206\uff0c\u53ef\u80fd\u5e2e\u52a9\u5468\u56f4\u7ec6\u80de\u4fee\u590d\u81ea\u8eab\u7ebf\u7c92\u4f53\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8bb8\u591a\u8870\u5f31\u60a3\u8005\u5728\u6cbb\u7597\u540e\u6700\u5148\u611f\u53d7\u5230\u7684\u53d8\u5316\u662f&#8221;\u6ca1\u90a3\u4e48\u5bb9\u6613\u75b2\u52b3\u4e86&#8221;\uff0c\u8fd9\u4e0e\u8be5\u673a\u5236\u53ef\u80fd\u76f8\u5173\u3002 \u4f46\u9700\u8981\u8bf4\u660e\u7684\u662f\uff0c\u4eba\u4f53\u4e2d\u8be5\u673a\u5236\u7684\u76f4\u63a5\u8bc1\u636e\u76ee\u524d\u4ecd\u5c5e\u521d\u671f\u9636\u6bb5\uff0c\u6211\u4eec\u5982\u5b9e\u544a\u77e5\u8fd9\u4e00\u70b9\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-what-the-clinical-trial-data-shows-for-msc-therapy-and-frailty-related-outcomes-54\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u4e34\u5e8a\u6570\u636e\u8bf4\u660e\u4e86\u4ec0\u4e48\u2014\u2014\u5177\u4f53\u6570\u5b57\u4e0e\u771f\u5b9e\u610f\u4e49<\/mark><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-the-cratus-trial-key-evidence-for-allogeneic-msc-therapy-in-aging-frailty-55\">CRATUS\u8bd5\u9a8c\u2014\u2014\u8001\u5e74\u8870\u5f31MSC\u6cbb\u7597\u7684\u6838\u5fc3\u8bc1\u636e<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u76f4\u63a5\u9488\u5bf9\u8870\u8001\u8870\u5f31\u75c7\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u6700\u91cd\u8981\u5df2\u53d1\u8868\u4e34\u5e8a\u8bd5\u9a8c\u662f\u8fc8\u963f\u5bc6\u5927\u5b66\u7c73\u52d2\u533b\u5b66\u9662\u5f00\u5c55\u7684 CRATUS \u9879\u76ee\uff0c\u5176\u4e3b\u8981\u7814\u7a76\u7ed3\u679c\u7531 Tompkins \u53ca\u5176\u540c\u4e8b\u4e8e 2017 \u5e74\u53d1\u8868\u5728\u300a\u8001\u5e74\u5b66\u300b\uff08Gerontology\uff09\u6742\u5fd7\u4e0a\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8be5\u8bd5\u9a8c\u62db\u52df\u4e86\u7b26\u5408 Fried \u8870\u5f31\u6807\u51c6\u7684\u8870\u5f31\u8001\u5e74\u4eba\u2014\u2014\u8fd9\u662f\u57fa\u4e8e\u65e0\u610f\u4f53\u91cd\u51cf\u8f7b\u3001\u75b2\u52b3\u3001\u865a\u5f31\u3001\u6b65\u884c\u901f\u5ea6\u6162\u548c\u4f4e\u4f53\u529b\u6d3b\u52a8\u7684\u8870\u5f31\u6807\u51c6\u4e34\u5e8a\u5b9a\u4e49\u2014\u2014\u5e76\u5bf9\u5176\u8fdb\u884c\u4e86\u4e0d\u540c\u5242\u91cf\u7684\u5f02\u4f53\u9aa8\u9ad3\u6765\u6e90\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSCs\uff09\u5355\u6b21\u9759\u8109\u8f93\u6ce8\u6216\u5b89\u6170\u5242\u5bf9\u7167\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5df2\u53d1\u8868\u7ed3\u679c\u4e2d\u7684\u53d1\u73b0\u503c\u5f97\u51c6\u786e\u5448\u73b0\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5728\u516d\u4e2a\u6708\u65f6\uff0c\u63a5\u53d7 MSCs \u8f93\u6ce8\u7684\u60a3\u8005\u4e0e\u63a5\u53d7\u5b89\u6170\u5242\u7684\u60a3\u8005\u76f8\u6bd4\uff0c\u5728\u4f53\u80fd\u6d4b\u8bd5\u4e2d\u8868\u73b0\u51fa\u7edf\u8ba1\u5b66\u4e0a\u7684\u663e\u8457\u6539\u5584\u3002\u516d\u5206\u949f\u6b65\u884c\u6d4b\u8bd5\u2014\u2014\u8870\u5f31\u7814\u7a76\u4e2d\u5e7f\u6cdb\u4f7f\u7528\u7684\u529f\u80fd\u6027\u8fd0\u52a8\u80fd\u529b\u6807\u51c6\u8861\u91cf\u6307\u6807\u2014\u2014\u663e\u793a\u6cbb\u7597\u7ec4\u60a3\u8005\u7684\u6b65\u884c\u8ddd\u79bb\u6709\u663e\u8457\u6539\u5584\uff0c\u800c\u5b89\u6170\u5242\u7ec4\u5219\u6ca1\u6709\u76f8\u5e94\u7684\u53d8\u5316\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u708e\u75c7\u6807\u5fd7\u7269\u4e5f\u5448\u73b0\u51fa\u7c7b\u4f3c\u7684\u60c5\u51b5\u3002\u80bf\u7624\u574f\u6b7b\u56e0\u5b50-\u03b1\uff08TNF-alpha\uff09\u2014\u2014\u4e0e\u201c\u708e\u6027\u8870\u8001\u201d\u548c\u8870\u5f31\u8fdb\u5c55\u76f8\u5173\u7684\u4e3b\u8981\u7ec6\u80de\u56e0\u5b50\u4e4b\u4e00\u2014\u2014\u5728\u6cbb\u7597\u7ec4\u60a3\u8005\u4e2d\u8f83\u57fa\u7ebf\u6c34\u5e73\u663e\u8457\u4e0b\u964d\uff0c\u4e14\u5728\u9ad8\u5242\u91cf\u7ec4\u4e2d\u4e0b\u964d\u6700\u4e3a\u660e\u663e\u3002\u8fd9\u662f\u4e00\u4e2a\u76f4\u63a5\u7684\u751f\u7269\u5b66\u4fe1\u53f7\uff0c\u8868\u660e\u6cbb\u7597\u6b63\u5728\u5f71\u54cd\u708e\u75c7\u73af\u5883\uff0c\u800c\u975e\u4ec5\u4ec5\u4ea7\u751f\u75c7\u72b6\u6027\u7684\u5b89\u6170\u5242\u6548\u5e94\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6cbb\u7597\u7ec4\u60a3\u8005\u7684\u751f\u6d3b\u8d28\u91cf\u8bc4\u5206\u548c\u81ea\u6211\u62a5\u544a\u7684\u8eab\u4f53\u529f\u80fd\u4e5f\u6709\u6240\u6539\u5584\u3002\u5728\u6240\u6709\u5242\u91cf\u7ec4\u4e2d\uff0c\u5747\u672a\u53d1\u73b0\u5f52\u56e0\u4e8e\u5e72\u7ec6\u80de\u8f93\u6ce8\u7684\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7531 Golpanian \u53ca\u5176\u540c\u4e8b\u4e8e 2017 \u5e74\u53d1\u8868\u5728\u300a\u8001\u5e74\u5b66\u6742\u5fd7\u300b\uff08Journals of Gerontology\uff09\u4e0a\u7684\u4e00\u9879\u914d\u5957 II \u671f\u7814\u7a76\uff0c\u91c7\u7528\u968f\u673a\u3001\u76f2\u6cd5\u3001\u5242\u91cf\u9012\u589e\u8bbe\u8ba1\u62db\u52df\u4e86 30 \u540d\u8870\u5f31\u8001\u5e74\u4eba\u3002\u8be5\u7814\u7a76\u8bc1\u5b9e\u4e86\u5176\u5b89\u5168\u6027\uff0c\u5e76\u62a5\u544a\u79f0\u4e0e\u5b89\u6170\u5242\u7ec4\u76f8\u6bd4\uff0c\u6cbb\u7597\u7ec4\u60a3\u8005\u5728 12 \u4e2a\u6708\u65f6\u7684\u516d\u5206\u949f\u6b65\u884c\u8ddd\u79bb\u548c\u6700\u5927\u6444\u6c27\u91cf\uff08\u8861\u91cf\u5fc3\u80ba\u8010\u529b\u7684\u6307\u6807\uff09\u6709\u6240\u6539\u5584\u3002\u6cbb\u7597\u7ec4\u5728 12 \u4e2a\u6708\u65f6\u7684\u516d\u5206\u949f\u6b65\u884c\u6d4b\u8bd5\u4e2d\u5e73\u5747\u6bd4\u57fa\u7ebf\u591a\u8d70\u7ea6 60 \u7c73\u2014\u2014\u8fd9\u4e00\u53d8\u5316\u5728\u4e34\u5e8a\u4e0a\u8f6c\u5316\u4e3a\u65e5\u5e38\u529f\u80fd\u7684\u663e\u8457\u6539\u5584\u3002<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-what-additional-research-on-mscs-and-sarcopenia-shows-64\">\u5173\u4e8e MSCs \u4e0e\u808c\u8089\u51cf\u5c11\u75c7\u7684\u5176\u4ed6\u7814\u7a76\u663e\u793a<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u9664\u4e86\u9488\u5bf9\u8870\u5f31\u75c7\u7684\u7279\u5b9a\u8bd5\u9a8c\u5916\uff0c\u5173\u4e8e MSCs \u5bf9\u808c\u8089\u51cf\u5c11\u75c7\uff08\u808c\u8089\u91cf\u6d41\u5931\uff09\u5f71\u54cd\u7684\u66f4\u5e7f\u6cdb\u7814\u7a76\u4e5f\u652f\u6301\u4e86\u8fd9\u4e9b\u4e34\u5e8a\u53d1\u73b0\u7684\u751f\u7269\u5b66\u5408\u7406\u6027\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2021 \u5e74\u53d1\u8868\u5728\u300a\u5e72\u7ec6\u80de\u7814\u7a76\u4e0e\u6cbb\u7597\u300b\uff08Stem Cell Research &amp; Therapy\uff09\u4e0a\u7684\u4e00\u9879\u4e34\u5e8a\u524d\u7814\u7a76\u8868\u660e\uff0c\u5728\u8001\u5e74\u52a8\u7269\u6a21\u578b\u4e2d\uff0c\u5168\u8eab\u6027\u7ed9\u4e88 MSCs \u4e0e\u672a\u6cbb\u7597\u7684\u5bf9\u7167\u7ec4\u76f8\u6bd4\uff0c\u4fdd\u7559\u4e86\u808c\u8089\u91cf\u5e76\u6539\u5584\u4e86\u808c\u7ea4\u7ef4\u7ec4\u6210\uff0c\u5176\u6548\u679c\u4e0e\u5c40\u90e8\u808c\u8089\u708e\u75c7\u51cf\u5c11\u548c\u536b\u661f\u7ec6\u80de\u6d3b\u6027\u63d0\u9ad8\u6709\u5173\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u53d1\u8868\u5728\u300a\u7ec6\u80de\u4e0e\u53d1\u80b2\u751f\u7269\u5b66\u524d\u6cbf\u300b\uff08Frontiers in Cell and Developmental Biology\uff09\u4e0a\u7684\u4e00\u9879\u7cfb\u7edf\u8bc4\u4ef7\u7814\u7a76\u4e86\u9488\u5bf9\u8870\u8001\u76f8\u5173\u75be\u75c5\u7684 MSC \u7597\u6cd5\uff0c\u53d1\u73b0\u901a\u8fc7\u5faa\u73af\u7ec6\u80de\u56e0\u5b50\u51cf\u5c11\u6240\u8861\u91cf\u7684\u6297\u708e\u4f5c\u7528\u5177\u6709\u4e00\u81f4\u8bc1\u636e\uff0c\u4e14\u5728\u5927\u591a\u6570\u7eb3\u5165\u8bc4\u4f30\u7684\u8bd5\u9a8c\u4e2d\uff0c\u529f\u80fd\u6027\u7ed3\u679c\uff08\u8fd0\u52a8\u80fd\u529b\u3001\u8fd0\u52a8\u80fd\u529b\u8bc4\u5206\uff09\u5747\u663e\u793a\u51fa\u6539\u5584\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"759\" height=\"394\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/Chinese-1.webp\" alt=\"\u5c55\u793a\u8001\u5e74\u8870\u5f31\u7efc\u5408\u5f81\u60a3\u8005\u63a5\u53d7\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff08MSC\uff09\u8f93\u6ce812\u4e2a\u6708\u540e\u516d\u5206\u949f\u6b65\u884c\u8ddd\u79bb\u6539\u5584\u7684\u67f1\u72b6\u56fe\uff08\u57fa\u4e8eGolpanian et al. 2017\u6570\u636e\uff09\" class=\"wp-image-24306\" style=\"width:592px\" srcset=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/Chinese-1.webp 759w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/Chinese-1-300x156.webp 300w\" sizes=\"(max-width: 759px) 100vw, 759px\" \/><figcaption class=\"wp-element-caption\">MSC\u6cbb\u7597\u7ec4\u8f83\u57fa\u7ebf\u5e73\u5747\u6539\u5584\u7ea660\u7c73\uff08\u7ea620%\u7684\u529f\u80fd\u63d0\u5347\uff09\u3002\u5b89\u6170\u5242\u7ec4\u65e0\u7edf\u8ba1\u5b66\u663e\u8457\u53d8\u5316\u3002\u6765\u6e90\uff1aGolpanian et al., Journals of Gerontology, 2017\u3002<\/figcaption><\/figure>\n<\/div>\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-what-the-numbers-mean-in-realistic-terms-for-frailty-patients-69\">\u8fd9\u4e9b\u6570\u5b57\u5728\u65e5\u5e38\u751f\u6d3b\u4e2d\u610f\u5473\u7740\u4ec0\u4e48<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">60\u7c73\u7684\u516d\u5206\u949f\u6b65\u884c\u6539\u5584\uff0c\u5bf9\u5e94\u5230\u771f\u5b9e\u751f\u6d3b\u662f\u4ec0\u4e48\uff1f<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5982\u679c\u4e00\u4f4d\u8870\u5f31\u8001\u4eba\u7684\u516d\u5206\u949f\u6b65\u884c\u57fa\u7ebf\u7ea6\u4e3a300\u7c73\uff0c\u6539\u558460\u7c73\u610f\u5473\u7740\u7ea620%\u7684\u529f\u80fd\u63d0\u5347\u3002 \u80fd\u72ec\u7acb\u8d70\u5230\u697c\u4e0b\u4fbf\u5229\u5e97\uff0c\u4e0d\u9700\u8981\u4e2d\u9014\u505c\u4e0b\u6765\u3002\u5750\u516c\u4ea4\u4e0d\u518d\u62c5\u5fc3\u4ece\u7ad9\u53f0\u8d70\u5230\u5ea7\u4f4d\u3002\u5916\u51fa\u540e\u7684\u75b2\u52b3\u611f\u4e0d\u518d\u5ef6\u7eed\u5230\u7b2c\u4e8c\u5929\u3002\u8fd9\u4e9b\u53d8\u5316\uff0c\u5bf9\u4e8e\u4e00\u4e2a\u4e16\u754c\u6b63\u5728\u7f29\u5c0f\u7684\u4eba\u6765\u8bf4\uff0c\u5e76\u4e0d\u662f\u5c0f\u4e8b\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4f46\u540c\u6837\u9700\u8981\u8bda\u5b9e\u5730\u8bf4\u660e\u6570\u636e\u7684\u5c40\u9650\u3002 \u5e76\u975e\u6240\u6709\u60a3\u8005\u90fd\u5f97\u5230\u4e86\u540c\u7b49\u7a0b\u5ea6\u7684\u6539\u5584\u3002 \u6839\u636e\u73b0\u6709\u8bd5\u9a8c\u6570\u636e\u7684\u4f30\u7b97\uff0c\u7ea620~30%\u7684\u53d7\u8bd5\u8005\u672a\u80fd\u83b7\u5f97\u6709\u4e34\u5e8a\u610f\u4e49\u7684\u6539\u5584\u3002 \u76ee\u524d\u6ca1\u6709\u53ef\u9760\u7684\u65b9\u6cd5\u5728\u6cbb\u7597\u524d\u786e\u5b9a\u5730\u9884\u6d4b\u8c01\u4f1a\u54cd\u5e94\u3001\u8c01\u4e0d\u4f1a\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-who-is-and-is-not-a-suitable-candidate-for-stem-cell-therapy-for-aging-frailty-74\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u54ea\u4e9b\u4eba\u9002\u5408\u3001\u54ea\u4e9b\u4eba\u4e0d\u9002\u5408\u5e72\u7ec6\u80de\u6cbb\u7597<\/mark><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-patient-profiles-that-tend-to-show-response-in-aging-frailty-trials-75\">\u53ef\u80fd\u4ece\u8001\u5e74\u8870\u5f31\u5e72\u7ec6\u80de\u6cbb\u7597\u4e2d\u83b7\u76ca\u7684\u7279\u5f81<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u57fa\u4e8e\u4e34\u5e8a\u8bd5\u9a8c\u6570\u636e\u548c\u6211\u4eec\u5728\u9a6c\u6765\u897f\u4e9a\u8d85\u8fc7\u4e03\u5e74\u7684\u4e34\u5e8a\u7ecf\u9a8c\uff0c\u4ee5\u4e0b\u7279\u5f81\u7684\u60a3\u8005\u663e\u793a\u51fa\u8f83\u4e3a\u4e00\u81f4\u7684\u6539\u5584\u8d8b\u52bf\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7b26\u5408Fried\u6807\u51c6\u7684\u8870\u5f31\u8bca\u65ad\uff0c\u5c24\u5176\u662f\u8840\u6db2\u68c0\u67e5\u4e2dTNF-\u03b1\u3001IL-6\u3001CRP\u7b49\u708e\u75c7\u6807\u5fd7\u7269\u504f\u9ad8\u7684\u60a3\u8005\u2014\u2014\u5373\u708e\u6027\u8870\u8001\u660e\u786e\u5b58\u5728\u8005\u3002 \u8f7b\u81f3\u4e2d\u5ea6\u8870\u5f31\u9636\u6bb5\uff08\u516d\u5206\u949f\u6b65\u884c\u80fd\u884c\u8d70200\u7c73\u4ee5\u4e0a\uff0c\u6709\u529f\u80fd\u50a8\u5907\uff09\u3002 \u5df2\u575a\u6301\u8fd0\u52a8\u4e0e\u8425\u517b\u5e72\u9884\u7ea612\u4e2a\u6708\uff0c\u4f46\u529f\u80fd\u6539\u5584\u5df2\u8d8b\u4e8e\u505c\u6ede\u3002 \u65e0\u6076\u6027\u80bf\u7624\u3001\u6d3b\u52a8\u6027\u611f\u67d3\u3001\u4e0d\u53d7\u63a7\u7684\u81ea\u8eab\u514d\u75ab\u75be\u75c5\u3002 \u80fd\u591f\u63a5\u53d7\u6548\u679c\u9700\u89816~12\u4e2a\u6708\u9010\u6b65\u663e\u73b0\uff0c\u4e0d\u6025\u4e8e\u7acb\u5373\u89c1\u6548\u3002<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-when-stem-cell-therapy-for-aging-frailty-is-unlikely-to-be-appropriate-81\">\u4e0d\u9002\u5408\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u60c5\u5f62<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u9700\u8981\u8bda\u5b9e\u5730\u8bf4\u660e\u4e0d\u9002\u5408\u7684\u60c5\u5f62\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u91cd\u5ea6\u8870\u5f31\uff08\u9700\u8981\u5168\u9762\u62a4\u7406\u6216\u5df2\u5367\u5e8a\uff09\u9636\u6bb5\uff0c\u5e72\u7ec6\u80de\u53d1\u6325\u4f5c\u7528\u6240\u9700\u7684\u7ec6\u80de\u57fa\u7840\u5df2\u4e25\u91cd\u53d7\u635f\uff0c\u529f\u80fd\u6539\u5584\u7684\u53ef\u80fd\u6027\u6781\u4f4e\u3002\u5728\u8fd9\u4e00\u9636\u6bb5\uff0c\u6700\u5408\u9002\u7684\u65b9\u5411\u662f\u4ee5\u8212\u9002\u548c\u751f\u6d3b\u8d28\u91cf\u4e3a\u4e2d\u5fc3\u7684\u62a4\u7406\u652f\u6301\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7532\u72b6\u817a\u529f\u80fd\u51cf\u9000\u3001\u4e25\u91cd\u8d2b\u8840\u3001\u91cd\u5ea6\u7761\u7720\u547c\u5438\u6682\u505c\u7b49\u4ecd\u672a\u6cbb\u7597\u7684\u57fa\u7840\u75be\u75c5\uff0c\u662f\u8870\u5f31\u7684\u4e3b\u8981\u8bf1\u56e0\uff0c\u5e94\u5148\u6cbb\u7597\u8fd9\u4e9b\u95ee\u9898\uff0c\u800c\u4e0d\u662f\u5bc4\u5e0c\u671b\u4e8eMSC\u6cbb\u7597\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6d3b\u52a8\u6027\u6076\u6027\u80bf\u7624\u3001\u5168\u8eab\u6027\u611f\u67d3\u3001\u4e25\u91cd\u80be\u529f\u80fd\u969c\u788d\uff0c\u5c5e\u4e8e\u76ee\u524d\u7684\u7981\u5fcc\u75c7\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-a-patients-account-what-recovery-from-aging-frailty-looked-like-over-six-months-88\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u60a3\u8005\u81ea\u8ff0\uff1a\u516d\u4e2a\u6708\u95f4\u8870\u8001\u8870\u5f31\u75c7\u5eb7\u590d\u7684\u771f\u5b9e\u5386\u7a0b<\/mark><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u4f4d\u4e03\u5341\u591a\u5c81\u7684\u5973\u6027\u3002\u5979\u88ab\u533b\u751f\u6839\u636e Fried \u6807\u51c6\u6b63\u5f0f\u8bca\u65ad\u4e3a\u8870\u5f31\u75c7\uff0c\u4e14\u75c5\u60c5\u5df2\u6301\u7eed\u7ea6\u4e09\u5e74\u3002\u5728\u6700\u521d\u8bc4\u4f30\u65f6\uff0c\u5979\u7684\u516d\u5206\u949f\u6b65\u884c\u6d4b\u8bd5\u8ddd\u79bb\u4e3a 280 \u7c73\u3002\u63e1\u529b\u4f4e\u4e8e\u5176\u5e74\u9f84\u548c\u6027\u522b\u7684\u9608\u503c\u3002\u80bf\u7624\u574f\u6b7b\u56e0\u5b50-\u03b1 (TNF-alpha) \u548c C \u53cd\u5e94\u86cb\u767d (CRP) \u6c34\u5e73\u5747\u6709\u6240\u5347\u9ad8\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5979\u4e00\u76f4\u575a\u6301\u8fdb\u884c\u7269\u7406\u6cbb\u7597\uff0c\u4e00\u5e74\u591a\u6765\u4ece\u672a\u7f3a\u5e2d\u8fc7\u4e00\u6b21\u963b\u529b\u8bad\u7ec3\u3002\u5979\u7684\u86cb\u767d\u8d28\u6444\u5165\u91cf\u8fdc\u9ad8\u4e8e\u63a8\u8350\u7684\u6700\u4f4e\u6807\u51c6\u3002\u5c3d\u7ba1\u5982\u6b64\uff0c\u5728\u8fc7\u53bb\u7684\u5341\u4e8c\u4e2a\u6708\u91cc\uff0c\u5979\u7684\u8eab\u4f53\u673a\u80fd\u5e76\u6ca1\u6709\u5f97\u5230\u5b9e\u8d28\u6027\u7684\u6539\u5584\uff0c\u5979\u63cf\u8ff0\u4e86\u4e00\u79cd\u65e0\u6cd5\u7528\u6d3b\u52a8\u91cf\u6216\u7761\u7720\u6a21\u5f0f\u6765\u89e3\u91ca\u7684\u75b2\u60eb\u611f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2024 \u5e74\uff0c\u5979\u5728\u6211\u4eec\u4f4d\u4e8e\u9a6c\u6765\u897f\u4e9a\u7684\u8bca\u6240\u63a5\u53d7\u4e86\u5f02\u4f53\u8110\u5e26\u95f4\u5145\u8d28\u5e72\u7ec6\u80de (MSCs) \u6cbb\u7597\u3002\u6cbb\u7597\u524d\u8bc4\u4f30\u786e\u8ba4\uff0c\u6d3b\u8dc3\u7684\u201c\u708e\u6027\u8870\u8001\u201d\u53ef\u80fd\u662f\u5bfc\u81f4\u5979\u8fdb\u5165\u5e73\u53f0\u671f\u7684\u539f\u56e0\uff0c\u6cbb\u7597\u65b9\u6848\u4e5f\u968f\u4e4b\u8fdb\u884c\u4e86\u76f8\u5e94\u8bbe\u8ba1\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u524d\u516d\u5468\u6ca1\u6709\u51fa\u73b0\u660e\u663e\u7684\u53d8\u5316\u2014\u2014\u5979\u5f62\u5bb9\u8fd9\u6bb5\u65f6\u671f\u611f\u89c9\u5f88\u719f\u6089\uff0c\u56e0\u4e3a\u4e00\u5e74\u591a\u6765\u5979\u4e00\u76f4\u6ca1\u6709\u4efb\u4f55\u6539\u5584\u3002\u5230\u4e86\u7b2c\u5341\u5468\uff0c\u5979\u6ce8\u610f\u5230\u8fd0\u52a8\u540e\u7684\u75b2\u52b3\u6301\u7eed\u65f6\u95f4\u53d8\u77ed\u4e86\u3002\u5230\u4e86\u7b2c\u4e09\u4e2a\u6708\uff0c\u5979\u5f62\u5bb9\u65e9\u6668\u7684\u7cbe\u529b\u6c34\u5e73\u662f\u201c\u4e09\u5e74\u6765\u6211\u5bdf\u89c9\u5230\u7684\u7b2c\u4e00\u4e2a\u53d8\u5316\u201d\u3002\u5728\u516d\u4e2a\u6708\u7684\u91cd\u65b0\u8bc4\u4f30\u4e2d\uff0c\u5979\u7684\u516d\u5206\u949f\u6b65\u884c\u6d4b\u8bd5\u8ddd\u79bb\u8fbe\u5230\u4e86 335 \u7c73\u2014\u2014\u6bd4\u57fa\u51c6\u7ebf\u589e\u52a0\u4e86 55 \u7c73\u3002\u63e1\u529b\u6709\u5c0f\u5e45\u4f46\u53ef\u8861\u91cf\u7684\u63d0\u5347\u3002\u708e\u75c7\u6307\u6807\u663e\u793a\u4e0b\u964d\uff1aTNF-alpha \u6bd4\u6cbb\u7597\u524d\u6c34\u5e73\u964d\u4f4e\u4e86\u7ea6 30%\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5979\u7ee7\u7eed\u6267\u884c\u8fd0\u52a8\u548c\u8425\u517b\u8ba1\u5212\u3002\u5e72\u7ec6\u80de\u6cbb\u7597\u5c1a\u672a\u88ab\u5ba3\u5e03\u4e3a\u6c38\u4e45\u6027\u7684\u6210\u529f\u2014\u2014\u5979\u5c06\u5728\u7b2c\u5341\u4e8c\u4e2a\u6708\u548c\u7b2c\u5341\u516b\u4e2a\u6708\u63a5\u53d7\u540e\u7eed\u8bc4\u4f30\u3002\u4f46\u662f\uff0c\u5728\u575a\u6301\u4e86\u4e00\u5e74\u4f20\u7edf\u7597\u6cd5\u540e\u4f9d\u7136\u5b58\u5728\u7684\u5e73\u53f0\u671f\uff0c\u4f3c\u4e4e\u5df2\u7ecf\u53d1\u751f\u4e86\u8f6c\u53d8\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5979\u81ea\u5df1\u7684\u8868\u8ff0\u662f\uff1a\u201c\u6211\u4e0d\u6307\u671b\u91cd\u65b0\u53d8\u5e74\u8f7b\u3002\u6211\u53ea\u662f\u60f3\u505c\u6b62\u6076\u5316\u3002\u5230\u76ee\u524d\u4e3a\u6b62\uff0c\u60c5\u51b5\u4f3c\u4e4e\u6b63\u662f\u5982\u6b64\u3002\u201d<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u203b \u672c\u6587\u662f\u57fa\u4e8e\u4e34\u5e8a\u7ecf\u9a8c\u7684\u533f\u540d\u6848\u4f8b\u3002\u4e2a\u4eba\u6548\u679c\u56e0\u4eba\u800c\u5f02\uff0c\u65e0\u6cd5\u4fdd\u8bc1\u5bf9\u4efb\u4f55\u5176\u4ed6\u60a3\u8005\u5177\u6709\u76f8\u540c\u6548\u679c\u3002<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-why-allogeneic-umbilical-cord-derived-mscs-are-used-for-aging-frailty-in-malaysia-97\">\u4e3a\u4ec0\u4e48\u5728\u9a6c\u6765\u897f\u4e9a\u4f7f\u7528\u5f02\u4f53\u8110\u5e26\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u6cbb\u7597\u8870\u8001\u8870\u5f31\u75c7<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u7ec6\u80de\u6765\u6e90\u7684\u9009\u62e9\u81f3\u5173\u91cd\u8981\uff0c\u60a3\u8005\u7406\u5e94\u5f97\u5230\u6e05\u6670\u7684\u89e3\u91ca\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5728\u65e5\u672c\uff0c\u76ee\u524d\u7684\u518d\u751f\u533b\u5b66\u76d1\u7ba1\u6846\u67b6\u901a\u5e38\u4f7f\u7528\u81ea\u4f53\u5e72\u7ec6\u80de\u7597\u6cd5\u2014\u2014\u8fd9\u610f\u5473\u7740\u7ec6\u80de\u53d6\u81ea\u60a3\u8005\u81ea\u8eab\u7684\u9aa8\u9ad3\u6216\u8102\u80aa\u7ec4\u7ec7\uff0c\u7ecf\u8fc7\u5904\u7406\u540e\u91cd\u65b0\u6ce8\u5165\u3002\u6ca1\u6709\u514d\u75ab\u6392\u65a5\u98ce\u9669\u662f\u5176\u4e3b\u8981\u4f18\u52bf\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7136\u800c\uff0c\u4e13\u95e8\u9488\u5bf9\u8870\u8001\u8870\u5f31\u75c7\uff0c\u81ea\u4f53\u7597\u6cd5\u5b58\u5728\u4e00\u4e2a\u6839\u672c\u6027\u7684\u5c40\u9650\u3002\u4e00\u4f4d\u60a3\u6709\u8870\u5f31\u75c7\u7684 70 \u5c81\u60a3\u8005\u6240\u80fd\u63d0\u4f9b\u7684\u7ec6\u80de\uff0c\u672c\u8eab\u5c31\u662f\u8870\u8001\u4e14\u5904\u4e8e\u708e\u6027\u8870\u8001\u751f\u7269\u7cfb\u7edf\u4e0b\u7684\u4ea7\u7269\u3002\u53d1\u8868\u7684\u7814\u7a76\u5c06\u8870\u5f31\u8001\u4eba\u7684\u81ea\u4f53\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u4e0e\u5e74\u8f7b\u5065\u5eb7\u6350\u732e\u8005\u7684\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\u8fdb\u884c\u5bf9\u6bd4\uff0c\u4e00\u81f4\u8868\u660e\u8870\u5f31\u60a3\u8005\u7684\u7ec6\u80de\u589e\u6b96\u80fd\u529b\u8f83\u5f31\uff0c\u6709\u76ca\u751f\u957f\u56e0\u5b50\u7684\u5206\u6ccc\u8f83\u4f4e\uff0c\u4e14\u514d\u75ab\u8c03\u8282\u6d3b\u6027\u6709\u6240\u4e0b\u964d\u3002\u5b9e\u9645\u4e0a\uff0c\u4f60\u662f\u5728\u7528\u6765\u81ea\u540c\u4e00\u4e2a\u8870\u8001\u514d\u75ab\u7cfb\u7edf\u7684\u7ec6\u80de\uff0c\u53bb\u6cbb\u7597\u8be5\u7cfb\u7edf\u8870\u8001\u6240\u5bfc\u81f4\u7684\u708e\u75c7\u540e\u679c\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5728\u9a6c\u6765\u897f\u4e9a\u4f7f\u7528\u7684\u5f02\u4f53\u8110\u5e26\u95f4\u5145\u8d28\u5e72\u7ec6\u80de\uff0c\u6765\u6e90\u4e8e\u5065\u5eb7\u5206\u5a29\u65f6\u6350\u8d60\u7684\u8110\u5e26\u6c83\u987f\u6c0f\u80f6\uff08Wharton&#8217;s jelly\uff09\u5c42\uff0c\u4e14\u5f81\u5f97\u4e86\u6350\u8d60\u8005\u7684\u5b8c\u5168\u540c\u610f\u3002\u8fd9\u4e9b\u7ec6\u80de\u5177\u6709\u751f\u7269\u5b66\u4e0a\u7684\u5e74\u8f7b\u7279\u6027\uff0c\u9ad8\u5ea6\u6d3b\u8dc3\uff0c\u5e76\u643a\u5e26\u7279\u522b\u5f3a\u6548\u7684\u514d\u75ab\u8c03\u8282\u4fe1\u53f7\u3002\u7531\u4e8e\u5b83\u4eec\u8868\u8fbe\u7684\u3001\u901a\u5e38\u4f1a\u89e6\u53d1\u514d\u75ab\u6392\u65a5\u7684\u8868\u9762\u86cb\u767d\u6c34\u5e73\u6781\u4f4e\uff0c\u56e0\u6b64\u5c3d\u7ba1\u6765\u81ea\u4e0d\u540c\u4e2a\u4f53\uff0c\u53d1\u751f\u4e25\u91cd\u6392\u65a5\u53cd\u5e94\u7684\u60c5\u51b5\u4ecd\u5c5e\u7f55\u89c1\u3002\u5173\u4e8e\u8870\u5f31\u75c7\u7684\u4e34\u5e8a\u8bd5\u9a8c\u6570\u636e\uff08\u5305\u62ec CRATUS \u9879\u76ee\uff09\u5747\u4f7f\u7528\u4e86\u5f02\u4f53\u7ec6\u80de\uff0c\u8fd9\u610f\u5473\u7740\u76ee\u524d\u7684\u8bc1\u636e\u57fa\u7840\u76f4\u63a5\u652f\u6301\u8fd9\u79cd\u65b9\u6cd5\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-honest-risks-and-limitations-of-stem-cell-therapy-for-aging-frailty-103\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u8001\u5e74\u8870\u5f31\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u98ce\u9669\u4e0e\u8bda\u5b9e\u7684\u5c40\u9650<\/mark><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-known-side-effects-and-safety-profile-in-frailty-msc-trials-104\">\u5df2\u77e5\u526f\u4f5c\u7528\u4e0e\u5b89\u5168\u6027\u7279\u5f81<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u5728\u5df2\u53d1\u8868\u7684\u8870\u5f31\u76f8\u5173\u5e72\u7ec6\u80de\u8bd5\u9a8c\u4e2d\uff0c\u4e0d\u826f\u53cd\u5e94\u603b\u4f53\u4e0a\u8f83\u4e3a\u8f7b\u5fae\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8f93\u6ce8\u540e24~48\u5c0f\u65f6\u5185\u51fa\u73b0\u4f4e\u70ed\uff08\u7ea615~20%\u7684\u60a3\u8005\uff09\uff0c\u8f7b\u5ea6\u4e4f\u529b\u611f\uff0c\u4ee5\u53ca\u6570\u65e5\u5185\u7684\u808c\u8089\u9178\u75db\u662f\u4e3b\u8981\u62a5\u544a\u3002\u8fd9\u4e9b\u53cd\u5e94\u88ab\u8ba4\u4e3a\u662f\u514d\u75ab\u7cfb\u7edf\u8bc6\u522b\u4f9b\u4f53\u7ec6\u80de\u65f6\u7684\u5e94\u7b54\uff0c\u5927\u591a\u6570\u65e0\u9700\u7279\u522b\u5904\u7406\u5373\u53ef\u81ea\u884c\u6d88\u9000\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">CRATUS\u8bd5\u9a8c\u4e2d\uff0c\u4efb\u4f55\u5242\u91cf\u7ec4\u5747\u672a\u8bb0\u5f55\u5230\u5f52\u56e0\u4e8e\u5e72\u7ec6\u80de\u8f93\u6ce8\u7684\u4e25\u91cd\u4e0d\u826f\u4e8b\u4ef6\u3002 \u8d85\u8fc7\u4e24\u5e74\u7684\u957f\u671f\u5b89\u5168\u6027\u6570\u636e\u76ee\u524d\u4ecd\u6709\u9650\u2014\u2014\u8fd9\u662f\u6211\u4eec\u5766\u8bda\u544a\u77e5\u6bcf\u4f4d\u60a3\u8005\u7684\u5ba2\u89c2\u5c40\u9650\u3002<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-what-stem-cell-therapy-cannot-do-for-aging-frailty-110\">\u8001\u5e74\u8870\u5f31\u5e72\u7ec6\u80de\u6cbb\u7597\u505a\u4e0d\u5230\u7684\u4e8b<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u9700\u8981\u660e\u786e\u8bf4\u660e\u51e0\u70b9\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5e72\u7ec6\u80de\u6cbb\u7597\u65e0\u6cd5\u5728\u77ed\u671f\u5185\u6062\u590d\u6570\u5341\u5e74\u79ef\u7d2f\u7684\u808c\u8089\u6d41\u5931\u3002 \u5b83\u4e5f\u4e0d\u80fd\u53d6\u4ee3\u8fd0\u52a8\u548c\u8425\u517b\u3002\u5728\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u53d6\u5f97\u8f83\u597d\u6548\u679c\u7684\u60a3\u8005\uff0c\u6cbb\u7597\u540e\u4ecd\u7136\u4fdd\u6301\u4e86\u8fd0\u52a8\u4e60\u60ef\u3002\u5e72\u7ec6\u80de\u6cbb\u7597\u66f4\u50cf\u662f&#8221;\u8ba9\u8fd0\u52a8\u7684\u6548\u679c\u66f4\u5bb9\u6613\u4ea7\u751f\u7684\u751f\u7269\u5b66\u57fa\u7840&#8221;\uff0c\u800c\u4e0d\u662f\u8fd0\u52a8\u7684\u66ff\u4ee3\u54c1\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5bf9\u4e8e\u91cd\u5ea6\u8870\u5f31\uff0c\u6216\u8005\u5bfc\u81f4\u8870\u5f31\u7684\u57fa\u7840\u75be\u75c5\u5c1a\u672a\u6cbb\u7597\u7684\u60c5\u51b5\uff0c\u65e0\u6cd5\u671f\u5f85\u76f4\u63a5\u6539\u5584\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u518d\u6b21\u5f3a\u8c03\uff0c\u7ea620~30%\u7684\u60a3\u8005\u672a\u80fd\u83b7\u5f97\u6709\u4e34\u5e8a\u610f\u4e49\u7684\u6539\u5584\u3002\u5728\u4f5c\u51fa\u4efb\u4f55\u51b3\u5b9a\u4e4b\u524d\uff0c\u77e5\u9053\u8fd9\u4e2a\u6570\u5b57\u662f\u60a3\u8005\u5e94\u6709\u7684\u6743\u5229\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"tw-target-text\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u5173\u4e8e\u8870\u8001\u3001\u865a\u5f31\u548c\u5e72\u7ec6\u80de\u7597\u6cd5\u7684\u5e38\u89c1\u95ee\u9898<\/mark><\/h2>\n\n\n\n<div data-wp-context=\"{ &quot;autoclose&quot;: false, &quot;accordionItems&quot;: [] }\" data-wp-interactive=\"core\/accordion\" role=\"group\" class=\"wp-block-accordion is-layout-flow wp-block-accordion-is-layout-flow\">\n<div data-wp-class--is-open=\"state.isOpen\" data-wp-context=\"{ &quot;id&quot;: &quot;accordion-item-1&quot;, &quot;openByDefault&quot;: false }\" data-wp-init=\"callbacks.initAccordionItems\" data-wp-on-window--hashchange=\"callbacks.hashChange\" class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h4 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-1-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" id=\"accordion-item-1\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span class=\"wp-block-accordion-heading__toggle-title\">\u9a6c\u6765\u897f\u4e9a\u7684\u6cbb\u7597\u4e0e\u4e2d\u56fd\u56fd\u5185\u6709\u4f55\u4e0d\u540c\uff1f<\/span><span class=\"wp-block-accordion-heading__toggle-icon\" aria-hidden=\"true\">+<\/span><\/button><\/h4>\n\n\n\n<div aria-labelledby=\"accordion-item-1\" data-wp-bind--hidden=\"state.isHidden\" data-wp-on--beforematch=\"actions.handleBeforeMatch\" id=\"accordion-item-1-panel\" role=\"region\" class=\"wp-block-accordion-panel is-layout-flow wp-block-accordion-panel-is-layout-flow\">\n<p class=\"wp-block-paragraph\">\u4e2d\u56fd\u56fd\u5185\u76ee\u524d\u5c1a\u65e0\u4e13\u95e8\u9488\u5bf9\u8001\u5e74\u8870\u5f31\u7efc\u5408\u5f81\u7684\u5e72\u7ec6\u80de\u6cbb\u7597\u7684\u6b63\u5f0f\u4e34\u5e8a\u8def\u5f84\u3002<br>\u9a6c\u6765\u897f\u4e9a\u63d0\u4f9b\u7684\u6cbb\u7597\u4f7f\u7528\u6765\u81ea\u5065\u5eb7\u65b0\u751f\u513f\u8110\u5e26\u7684\u4ed6\u4eba\u6765\u6e90MSC\u2014\u2014\u751f\u7269\u5b66\u5e74\u9f84\u8f7b\u3001\u514d\u75ab\u8c03\u8282\u80fd\u529b\u66f4\u5f3a\uff0c\u4e14\u4e0eCRATUS\u7b49\u4e3b\u8981\u4e34\u5e8a\u8bd5\u9a8c\u4f7f\u7528\u7684\u7ec6\u80de\u7c7b\u578b\u4e00\u81f4\u3002\u6cbb\u7597\u6709\u660e\u786e\u7684\u4e94\u6b65\u6d41\u7a0b\u548c\u7cfb\u7edf\u7684\u968f\u8bbf\u8ffd\u8e2a\u3002<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div data-wp-context=\"{ &quot;autoclose&quot;: false, &quot;accordionItems&quot;: [] }\" data-wp-interactive=\"core\/accordion\" role=\"group\" class=\"wp-block-accordion is-layout-flow wp-block-accordion-is-layout-flow\">\n<div data-wp-class--is-open=\"state.isOpen\" data-wp-context=\"{ &quot;id&quot;: &quot;accordion-item-2&quot;, &quot;openByDefault&quot;: false }\" data-wp-init=\"callbacks.initAccordionItems\" data-wp-on-window--hashchange=\"callbacks.hashChange\" class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h4 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-2-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" id=\"accordion-item-2\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span class=\"wp-block-accordion-heading__toggle-title\">\u6548\u679c\u4ec0\u4e48\u65f6\u5019\u4f1a\u5f00\u59cb\u663e\u73b0\uff1f<\/span><span class=\"wp-block-accordion-heading__toggle-icon\" aria-hidden=\"true\">+<\/span><\/button><\/h4>\n\n\n\n<div aria-labelledby=\"accordion-item-2\" data-wp-bind--hidden=\"state.isHidden\" data-wp-on--beforematch=\"actions.handleBeforeMatch\" id=\"accordion-item-2-panel\" role=\"region\" class=\"wp-block-accordion-panel is-layout-flow wp-block-accordion-panel-is-layout-flow\">\n<p class=\"wp-block-paragraph\">\u591a\u6570\u60a3\u8005\u5728\u8f93\u6ce8\u540e6~12\u5468\u5de6\u53f3\u5f00\u59cb\u611f\u53d7\u5230\u7b2c\u4e00\u4e2a\u53d8\u5316\u2014\u2014\u75b2\u52b3\u6062\u590d\u53d8\u5feb\u4e86\uff0c\u65e9\u6668\u8d77\u6765\u7cbe\u529b\u4e0d\u4e00\u6837\u4e86\u3002<br>\u6b65\u884c\u6d4b\u8bd5\u6216\u708e\u75c7\u6807\u5fd7\u7269\u7b49\u5ba2\u89c2\u6307\u6807\u51fa\u73b0\u53d8\u5316\u7684\u65f6\u95f4\u8282\u70b9\u901a\u5e38\u57283~6\u4e2a\u6708\u3002<br>6\u4e2a\u6708\u65f6\u6ca1\u6709\u4efb\u4f55\u611f\u53d7\u53d8\u5316\u7684\u60a3\u8005\uff0c12\u4e2a\u6708\u65f6\u51fa\u73b0\u663e\u8457\u6539\u5584\u7684\u6982\u7387\u4e5f\u8f83\u4f4e\u3002<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div data-wp-context=\"{ &quot;autoclose&quot;: false, &quot;accordionItems&quot;: [] }\" data-wp-interactive=\"core\/accordion\" role=\"group\" class=\"wp-block-accordion is-layout-flow wp-block-accordion-is-layout-flow\">\n<div data-wp-class--is-open=\"state.isOpen\" data-wp-context=\"{ &quot;id&quot;: &quot;accordion-item-3&quot;, &quot;openByDefault&quot;: false }\" data-wp-init=\"callbacks.initAccordionItems\" data-wp-on-window--hashchange=\"callbacks.hashChange\" class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h4 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-3-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" id=\"accordion-item-3\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span class=\"wp-block-accordion-heading__toggle-title\">\u6211\u540c\u65f6\u6709\u5fc3\u529b\u8870\u7aed\/\u7c7b\u98ce\u6e7f\u5173\u8282\u708e\uff0c\u53ef\u4ee5\u63a5\u53d7\u6cbb\u7597\u5417\uff1f<\/span><span class=\"wp-block-accordion-heading__toggle-icon\" aria-hidden=\"true\">+<\/span><\/button><\/h4>\n\n\n\n<div aria-labelledby=\"accordion-item-3\" data-wp-bind--hidden=\"state.isHidden\" data-wp-on--beforematch=\"actions.handleBeforeMatch\" id=\"accordion-item-3-panel\" role=\"region\" class=\"wp-block-accordion-panel is-layout-flow wp-block-accordion-panel-is-layout-flow\">\n<p 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human mesenchymal stem cell infusions for aging frailty.&#8221; <em>Journals of Gerontology: Biological Sciences.<\/em> 2017;72(11):1505\u20131512. <a href=\"https:\/\/doi.org\/10.1093\/gerona\/glw217\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1093\/gerona\/glw217<\/a><br><\/li>\n\n\n\n<li>Fried LP, Tangen CM, Walston J, et al. &#8220;Frailty in older adults: evidence for a phenotype.&#8221; <em>Journals of Gerontology: Medical Sciences.<\/em> 2001;56(3):M146\u2013M156. <a href=\"https:\/\/doi.org\/10.1093\/gerona\/56.3.M146\">https:\/\/doi.org\/<\/a><a href=\"https:\/\/doi.org\/10.1093\/gerona\/56.3.M146\" target=\"_blank\" rel=\"noopener\" title=\"\">10.1093<\/a><a href=\"https:\/\/doi.org\/10.1093\/gerona\/56.3.M146\">\/gerona\/56.3.M146<\/a><br><\/li>\n\n\n\n<li>Ferrucci L, Fabbri E. &#8220;Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty.&#8221; <em>Nature Reviews Cardiology.<\/em> 2018;15(9):505\u2013522. <a href=\"https:\/\/doi.org\/10.1038\/s41569-018-0064-2\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1038\/s41569-018-0064-2<\/a><br><\/li>\n\n\n\n<li>Clegg A, Young J, Iliffe S, Rikkert MO, Rockwood K. &#8220;Frailty in elderly people.&#8221; <em>The Lancet.<\/em> 2013;381(9868):752\u2013762. <a href=\"https:\/\/doi.org\/10.1016\/S0140-6736(12)62167-9\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1016\/S0140-6736(12)62167-9<\/a><br><\/li>\n\n\n\n<li>Cruz-Jentoft AJ, Bahat G, Bauer J, et al. &#8220;Sarcopenia: revised European consensus on definition and diagnosis.&#8221; <em>Age and Ageing.<\/em> 2019;48(1):16\u201331. <a href=\"https:\/\/doi.org\/10.1093\/ageing\/afy169\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1093\/ageing\/afy169<\/a><br><\/li>\n\n\n\n<li>Sun Y, Wan B, Wang R, et al. &#8220;Mesenchymal stem cell therapy reverses age-related impairment of muscle regeneration and ameliorates sarcopenia in aging muscle.&#8221; <em>Stem Cell Research &amp; Therapy.<\/em> 2021;12(1):419. <a href=\"https:\/\/doi.org\/10.1186\/s13287-021-02496-2\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1186\/s13287-021-02496-2<\/a><br><\/li>\n\n\n\n<li>Dimmeler S, Leri A. &#8220;Aging and disease as modifiers of efficacy of cell therapy.&#8221; <em>Circulation Research.<\/em> 2008;102(11):1319\u20131330. <a href=\"https:\/\/doi.org\/10.1161\/CIRCRESAHA.108.175174\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1161\/CIRCRESAHA.108.175174<\/a><\/li>\n<\/ol>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\t\t<div data-elementor-type=\"section\" data-elementor-id=\"21880\" class=\"elementor elementor-21880\" data-elementor-post-type=\"elementor_library\">\n\t\t\t        <section class=\"elementor-section elementor-top-section elementor-element elementor-element-a6ebaad elementor-section-boxed 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