{"id":22926,"date":"2026-03-10T15:53:23","date_gmt":"2026-03-10T07:53:23","guid":{"rendered":"https:\/\/stemcell-malaysia.com\/?p=22926"},"modified":"2026-07-19T12:49:32","modified_gmt":"2026-07-19T04:49:32","slug":"eli-lilly-pays-2-4-billion-for-orna-therapeutics-to-push-forward-next-generation-cell-therapy","status":"publish","type":"post","link":"https:\/\/stemcell-malaysia.com\/ko\/eli-lilly-pays-2-4-billion-for-orna-therapeutics-to-push-forward-next-generation-cell-therapy\/","title":{"rendered":"\uc77c\ub77c\uc774 \ub9b4\ub9ac, \ucc28\uc138\ub300 \uc138\ud3ec \uce58\ub8cc\uc81c \ucd94\uc9c4\uc744 \uc704\ud574 \uc624\ub974\ub098 \ud14c\ub77c\ud4e8\ud2f1\uc2a4\uc5d0 24\uc5b5 \ub2ec\ub7ec \uc9c0\ubd88"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"22926\" class=\"elementor elementor-22926\" data-elementor-post-type=\"post\">\n\t\t\t\t        <section class=\"elementor-section elementor-top-section elementor-element elementor-element-3bfd4e1c elementor-section-boxed elementor-section-height-default elementor-section-height-default pxl-row-scroll-none pxl-zoom-point-false pxl-section-overflow-visible pxl-section-fix-none pxl-bg-color-none pxl-section-overlay-none\" data-id=\"3bfd4e1c\" data-element_type=\"section\">\n\n                \n                <div class=\"elementor-container elementor-column-gap-default \">\n                <div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-2cd9cc31 pxl-column-none pxl-column-overflow-hidden-no\" data-id=\"2cd9cc31\" data-element_type=\"column\">\r\n        <div class=\"elementor-widget-wrap elementor-element-populated\">\r\n                     \r\n        \t\t<div class=\"elementor-element elementor-element-e3acb24 elementor-widget elementor-widget-text-editor\" data-id=\"e3acb24\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t\n<h1 style=\"text-align: center;\">\uc77c\ub77c\uc774 \ub9b4\ub9ac, \ucc28\uc138\ub300 \uc138\ud3ec \uce58\ub8cc\uc81c \ucd94\uc9c4\uc744 \uc704\ud574 \uc624\ub974\ub098 \ud14c\ub77c\ud4e8\ud2f1\uc2a4\uc5d0 24\uc5b5 \ub2ec\ub7ec \uc9c0\ubd88<\/h1>\n\n<figure><img decoding=\"async\" class=\"aligncenter\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/03\/pexels-artempodrez-5726796-1024x576.jpg\" alt=\"\" \/><\/figure>\n\n<p class=\"wp-block-paragraph\" style=\"text-align: center;\"><em>\uc77c\ub77c\uc774 \ub9b4\ub9ac(Eli Lilly)\ub294 \uc790\uac00\uba74\uc5ed \uc9c8\ud658(autoimmune diseases)\uc744 \uce58\ub8cc\ud558\uae30 \uc704\ud574 \ud658\uc0c1 RNA(circular RNA) \ubc0f \uc904\uae30\uc138\ud3ec(stem cells) \uc5f0\uad6c\ub97c \ud65c\uc6a9\ud55c \uccb4\ub0b4 CAR-T \uc138\ud3ec \uce58\ub8cc(in vivo CAR-T cell therapy)\ub97c \ubc1c\uc804\uc2dc\ud0a4\uace0\uc790 \ucd5c\ub300 24\uc5b5 \ub2ec\ub7ec\uc5d0 \uc624\ub974\ub098 \ud14c\ub77c\ud4e8\ud2f1\uc2a4(Orna Therapeutics)\ub97c \uc778\uc218\ud55c\ub2e4.<\/em><\/p>\n\n<h1 class=\"wp-block-heading\" style=\"text-align: center;\">\u00a0<\/h1>\n<h2 style=\"text-align: center;\" data-path-to-node=\"42\">\uc77c\ub77c\uc774 \ub9b4\ub9ac, \ucc28\uc138\ub300 \uc138\ud3ec \uce58\ub8cc\uc81c \ubc1c\uc804\uc744 \uc704\ud574 \uc624\ub974\ub098 \ud14c\ub77c\ud4e8\ud2f1\uc2a4\ub97c 24\uc5b5 \ub2ec\ub7ec\uc5d0 \uc778\uc218<\/h2>\n\n<p class=\"wp-block-paragraph\" data-path-to-node=\"43\">\ub9cc\uc57d \uc218\uc8fc\uac04\uc758 \uc2e4\ud5d8\uc2e4 \uc808\ucc28\ub098 \uc785\uc6d0 \uc5c6\uc774 \ub2f9\uc2e0\uc758 \uc2e0\uccb4\uac00 \uc2a4\uc2a4\ub85c \uce58\uc720\ud558\ub3c4\ub85d \uc9c0\uc2dc\ubc1b\uc744 \uc218 \uc788\ub2e4\uba74 \uc5b4\ub5a8\uae4c\uc694? \uc774\uac83\uc774 2026\ub144 2\uc6d4 9\uc77c\uc5d0 \ubc1c\ud45c\ub41c, \ucd5c\ub300 24\uc5b5 \ub2ec\ub7ec\uc5d0 \uc624\ub974\ub098 \ud14c\ub77c\ud4e8\ud2f1\uc2a4\ub97c \uc778\uc218\ud558\uae30\ub85c \ud55c \uc77c\ub77c\uc774 \ub9b4\ub9ac\uc758 \uacb0\uc815 \uc774\uba74\uc5d0 \uc788\ub294 \ud575\uc2ec \uc544\uc774\ub514\uc5b4\uc785\ub2c8\ub2e4. \uc774 \uac70\ub798\uc758 \uc911\uc2ec\uc5d0\ub294 \uc870\uc791\ub41c RNA(engineered RNA) \ubd84\uc790\ub97c \uc0ac\uc6a9\ud558\uc5ec \uc778\uccb4 \ub0b4\ubd80\uc5d0\uc11c \uc790\uccb4 \uba74\uc5ed \uc138\ud3ec(immune cells)\ub97c \uc7ac\ud504\ub85c\uadf8\ub798\ubc0d\ud558\ub294 \uae30\uc220\uc774 \uc788\uc73c\uba70, \uc774\ub294 \uc9c4\ud654\ud558\ub294 \uc138\ud3ec \uce58\ub8cc\uc81c(cell therapy) \ubc0f \uc904\uae30\uc138\ud3ec \uc5f0\uad6c \ubd84\uc57c\uc5d0\uc11c \uc911\uc694\ud55c \uc9c4\uc804\uc744 \uc758\ubbf8\ud569\ub2c8\ub2e4.<\/p>\n\n<h2 class=\"wp-block-heading\" style=\"text-align: center;\">\u00a0<\/h2>\n<h2 style=\"text-align: center;\" data-path-to-node=\"44\">\uac70\ub798\uc758 \ub0b4\uc6a9\uc740 \ubb34\uc5c7\uc774\uba70 \uc65c \uc911\uc694\ud55c\uac00?<\/h2>\n\n<p class=\"wp-block-paragraph\" data-path-to-node=\"45\">\uc138\uacc4 \ucd5c\ub300 \uc81c\uc57d \ud68c\uc0ac \uc911 \ud558\ub098\uc778 \uc77c\ub77c\uc774 \ub9b4\ub9ac\ub294 \ud658\uc0c1 RNA \uae30\uc220\uc744 \uc804\ubb38\uc73c\ub85c \ud558\ub294 \uc0dd\uba85\uacf5\ud559 \uae30\uc5c5(biotechnology company)\uc778 \uc624\ub974\ub098 \ud14c\ub77c\ud4e8\ud2f1\uc2a4\ub97c \uc778\uc218\ud558\uae30 \uc704\ud574 \ucd5c\ub300 24\uc5b5 \ub2ec\ub7ec\ub97c \ud604\uae08\uc73c\ub85c \uc9c0\ubd88\ud558\uae30\ub85c \ud569\uc758\ud588\uc2b5\ub2c8\ub2e4. \uc774 \uc9c0\ubd88\uc561\uc5d0\ub294 \uc120\ubd88\uae08\uacfc \ud568\uaed8 \uc774 \ud68c\uc0ac\uc758 \uc8fc\uc694 \uce58\ub8cc\uc81c\uac00 \uc784\uc0c1 \uc2dc\ud5d8(clinical trials)\uc5d0\uc11c \uc5bc\ub9c8\ub098 \uc6b0\uc218\ud55c \uc131\uacfc\ub97c \ub0b4\ub294\uc9c0\uc5d0 \ub530\ub978 \ucd94\uac00 \uc9c0\ubd88\uae08\uc774 \ud3ec\ud568\ub418\uc5b4 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<p data-path-to-node=\"46\">\uc774\ubc88 \uc778\uc218\ub97c \ud1b5\ud574 \uc77c\ub77c\uc774 \ub9b4\ub9ac\ub294 \uc624\ub974\ub098\uc758 \ud575\uc2ec \uae30\uc220 \ud50c\ub7ab\ud3fc, \uadf8 \uc804\ub2ec \uc2dc\uc2a4\ud15c(delivery system), \uadf8\ub9ac\uace0 \uac00\uc7a5 \uc9c4\ubcf4\ub41c \uc57d\ubb3c \ud6c4\ubcf4\ubb3c\uc9c8\uc778 ORN-252\ub77c\ub294 \uce58\ub8cc\uc81c\uc5d0 \ub300\ud55c \uc644\uc804\ud55c \uc18c\uc720\uad8c\uc744 \uac16\uac8c \ub429\ub2c8\ub2e4. \uc774\uac83\uc740 \ub2e8\uc21c\ud55c \ub2e8\uc77c \uc81c\ud488 \uad6c\ub9e4\uac00 \uc544\ub2d9\ub2c8\ub2e4. \uc77c\ub77c\uc774 \ub9b4\ub9ac\ub294 \ucd08\uae30 \ud45c\uc801\uc744 \ub118\uc5b4 \uc5ec\ub7ec \uc9c8\ubcd1\uc5d0 \uc801\uc6a9\ub420 \uc218 \uc788\ub2e4\uace0 \ubbff\ub294 \uc804\uccb4 \uae30\uc220 \uc778\ud504\ub77c\ub97c \uad6c\ub9e4\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<p data-path-to-node=\"47\">\uc774\ub7ec\ud55c \uc6c0\uc9c1\uc784\uc740 \uc774 \ud68c\uc0ac\uac00 \uad6c\ucd95\ud574 \uc628 \ud328\ud134\uacfc \uc77c\uce58\ud569\ub2c8\ub2e4. \uc77c\ub77c\uc774 \ub9b4\ub9ac\ub294 \ub9c8\uc6b4\uc790\ub85c(Mounjaro) \ubc0f \uc82d\ubc14\uc6b4\ub4dc(Zepbound)\ub77c\ub294 \ube0c\ub79c\ub4dc\ub85c \ud310\ub9e4\ub418\ub294 \ud2f0\ub974\uc81c\ud30c\ud0c0\uc774\ub4dc(tirzepatide)\ub97c \ud3ec\ud568\ud558\uc5ec \ud070 \uc131\uacf5\uc744 \uac70\ub454 \uccb4\uc911 \uad00\ub9ac \uc57d\ubb3c\uc5d0\uc11c \ucc3d\ucd9c\ub41c \uc218\uc775\uc744 \uc720\uc804\uc790 \ud3b8\uc9d1(gene editing) \ubc0f \uc774\uc81c\ub294 RNA \uae30\ubc18 \uc138\ud3ec \uce58\ub8cc\uc81c(RNA-based cell therapy)\ub97c \ud3ec\ud568\ud55c \uc2e0\ud765 \uc758\ud559 \ubd84\uc57c\uc5d0 \ud22c\uc790\ud574 \uc654\uc2b5\ub2c8\ub2e4.<\/p>\n<h2 style=\"text-align: center;\"><br \/>\uc624\ub974\ub098 \ud14c\ub77c\ud4e8\ud2f1\uc2a4\ub294 \ub204\uad6c\uc774\uba70 \ubb34\uc5c7\uc744 \ub9cc\ub4e4\uc5c8\ub098?<\/h2>\n\n<p class=\"wp-block-paragraph\" data-path-to-node=\"49\">\uc624\ub974\ub098 \ud14c\ub77c\ud4e8\ud2f1\uc2a4\ub294 \ud658\uc0c1 RNA \ub610\ub294 oRNA\ub77c\ub294 \uc0c8\ub85c\uc6b4 \uc720\ud615\uc758 RNA \ubd84\uc790\ub97c \uac1c\ubc1c\ud55c \uc0dd\uba85\uacf5\ud559 \uae30\uc5c5\uc785\ub2c8\ub2e4. \uc774\uac83\uc774 \uc65c \uc911\uc694\ud55c\uc9c0 \uc774\ud574\ud558\ub824\uba74, \uc804\ud1b5\uc801\uc778 RNA \uce58\ub8cc\uc81c\uac00 \uc5b4\ub5bb\uac8c \uc791\uc6a9\ud558\ub294\uc9c0 \uc870\uae08 \uc544\ub294 \uac83\uc774 \ub3c4\uc6c0\uc774 \ub429\ub2c8\ub2e4.<\/p>\n<p data-path-to-node=\"50\">COVID-19 \ub300\uc720\ud589 \uae30\uac04 \ub3d9\uc548 \uac1c\ubc1c\ub41c mRNA \ubc31\uc2e0(mRNA vaccines)\uacfc \uac19\uc740 \ub300\ubd80\ubd84\uc758 RNA \uae30\ubc18 \uc57d\ubb3c\uc740 \uc120\ud615 RNA(linear RNA)\ub85c \uad6c\uc131\ub429\ub2c8\ub2e4. \uc774 \ubd84\uc790\ub294 \ub450 \ub05d\uc774 \uc5f4\ub824 \uc788\uc5b4 \uccb4\ub0b4\uc5d0\uc11c \ube44\uad50\uc801 \ube60\ub974\uac8c \ubd84\ud574\ub429\ub2c8\ub2e4. \ub300\uc870\uc801\uc73c\ub85c, \uc624\ub974\ub098\uc758 \ud658\uc0c1 RNA\ub294 \uc5f4\ub9b0 \ub05d\uc774 \uc5c6\ub294 \ub2eb\ud78c \uace0\ub9ac\ub97c \ud615\uc131\ud558\uc5ec \ud604\uc800\ud558\uac8c \ub354 \uc548\uc815\uc801\uc785\ub2c8\ub2e4. \uc138\ud3ec \ub0b4\uc5d0\uc11c \ub354 \uc624\ub798 \uc9c0\uc18d\ub418\uace0, \ub354 \uc624\ub79c \uae30\uac04 \ub3d9\uc548 \ub2e8\ubc31\uc9c8\uc744 \uc0dd\uc131\ud558\uba70, \uc77c\uad00\ub418\uac8c \uc81c\uc870\ud558\uae30\uac00 \ub354 \uc27d\uc2b5\ub2c8\ub2e4.<\/p>\n\n<figure><img decoding=\"async\" class=\"aligncenter\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/03\/pexels-fayette-reynolds-m-s-181007507-11198493-1024x577.jpg\" alt=\"\" \/><\/figure>\n\n<p class=\"wp-block-paragraph\">\uc624\ub974\ub098\ub294 \uc774 \ud658\uc0c1 RNA\ub97c \uc9c0\uc9c8 \ub098\ub178\uc785\uc790(lipid nanoparticle, LNP)\ub77c\ub294 \uc804\ub2ec \ub9e4\uac1c\uccb4\uc640 \uc9dd\uc744 \uc774\ub8f9\ub2c8\ub2e4. \uc774\ub294 \ubcf8\uc9c8\uc801\uc73c\ub85c RNA\ub97c \uccb4\ub0b4\uc758 \ud2b9\uc815 \uc138\ud3ec\ub85c \uc6b4\ubc18\ud558\ub294 \uc791\uc740 \uc9c0\ubc29 \uae30\ubc18 \ucea1\uc290\uc785\ub2c8\ub2e4. \ud658\uc0c1 RNA\uc640 LNP\ub294 \ud568\uaed8 \uc790\uac00\uba74\uc5ed \uc9c8\ud658, \uc554(cancer), \uc720\uc804 \uc9c8\ud658(genetic disorders)\uc744 \ud3ec\ud568\ud55c \ub9ce\uc740 \uc9c8\ubcd1 \uc601\uc5ed\uc5d0 \uac78\uccd0 \uc7a0\uc7ac\uc801\uc73c\ub85c \uc0ac\uc6a9\ub420 \uc218 \uc788\ub294 \ud50c\ub7ab\ud3fc\uc758 \uae30\ucd08\ub97c \ud615\uc131\ud569\ub2c8\ub2e4.<\/p>\n\n<h2 class=\"wp-block-heading\" style=\"text-align: center;\"><br \/>\uc8fc\uc694 \uc57d\ubb3c \ud6c4\ubcf4\ubb3c\uc9c8: ORN-252<\/h2>\n\n<p class=\"wp-block-paragraph\">\uc624\ub974\ub098\uc758 \uac00\uc7a5 \uc9c4\ubcf4\ub41c \ud504\ub85c\uadf8\ub7a8\uc740 ORN-252\ub85c, \uba74\uc5ed \uc138\ud3ec\uc758 \uc77c\uc885\uc778 B\uc138\ud3ec(B cells) \ud45c\uba74\uc5d0\uc11c \ubc1c\uacac\ub418\ub294 CD19\ub77c\ub294 \ub2e8\ubc31\uc9c8\uc744 \ud45c\uc801\uc73c\ub85c \ud558\ub294 \uc2e4\ud5d8\uc801\uc778 \uccb4\ub0b4 CAR-T \uce58\ub8cc\uc81c\uc785\ub2c8\ub2e4. ORN-252\ub294 \uc804\uc784\uc0c1 \uc2dc\ud5d8(preclinical testing)\uc744 \uc644\ub8cc\ud588\uc73c\uba70 \uc778\uc218 \ubc1c\ud45c \ub2f9\uc2dc \uc778\uac04 \ud658\uc790\ub97c \ub300\uc0c1\uc73c\ub85c \ud55c \uc784\uc0c1 \uc2dc\ud5d8\uc5d0 \ub4e4\uc5b4\uac08 \uc900\ube44\uac00 \ub41c \uac83\uc73c\ub85c \uc124\uba85\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n\n<h3 class=\"wp-block-heading\" style=\"text-align: center;\"><br \/>ORN-252\ub294 \uae30\uc874 CAR-T \uce58\ub8cc\uc81c\uc640 \uc5b4\ub5bb\uac8c \ub2e4\ub978\uac00?<\/h3>\n\n<p class=\"wp-block-paragraph\" data-path-to-node=\"55\">ORN-252\uac00 \uc81c\uacf5\ud558\ub294 \uc774\uc810\uc744 \uc778\uc2dd\ud558\ub824\uba74, \ud45c\uc900 CAR-T \uce58\ub8cc\uc81c\uac00 \ud604\uc7ac \uc5b4\ub5bb\uac8c \uc791\uc6a9\ud558\ub294\uc9c0 \uc774\ud574\ud558\ub294 \uac83\uc774 \ub3c4\uc6c0\uc774 \ub429\ub2c8\ub2e4. \uc804\ud1b5\uc801\uc778 \uacfc\uc815\uc5d0\uc11c \uc758\uc0ac\ub4e4\uc740 \ud658\uc790\uc758 \ud608\uc561\uc5d0\uc11c T\uc138\ud3ec(T cells)\ub97c \ucd94\ucd9c\ud558\uc5ec \uc804\ubb38 \uc2e4\ud5d8\uc2e4\ub85c \ubcf4\ub0b4 \uc218 \uc8fc\uc5d0 \uac78\uccd0 \uc720\uc804\uc801\uc73c\ub85c \ubcc0\ud615\uc2dc\ud0a8 \ub2e4\uc74c, \ubcc0\ud615\ub41c \uc138\ud3ec\ub97c \ud658\uc790\uc5d0\uac8c \ub2e4\uc2dc \uc8fc\uc785\ud569\ub2c8\ub2e4. \uc774 \uacfc\uc815\uc740 \uc2dc\uac04\uc774 \ub9ce\uc774 \uac78\ub9ac\uace0, \uae30\uc220\uc801\uc73c\ub85c \ubcf5\uc7a1\ud558\uba70, \ud658\uc790\ub2f9 \uc218\uc2ed\ub9cc \ub2ec\ub7ec\uc5d0 \ub2ec\ud560 \uc815\ub3c4\ub85c \ube44\uc6a9\uc774 \ub9ce\uc774 \ub4ed\ub2c8\ub2e4.<\/p>\n<p data-path-to-node=\"56\">ORN-252\ub294 \uadfc\ubcf8\uc801\uc73c\ub85c \ub2e4\ub978 \uc811\uadfc\ubc95\uc744 \ucde8\ud569\ub2c8\ub2e4. \uccb4\ub0b4\uc5d0\uc11c \uc138\ud3ec\ub97c \uc81c\uac70\ud558\uc5ec \uc678\ubd80\uc5d0\uc11c \ubcc0\ud615\uc2dc\ud0a4\ub294 \ub300\uc2e0, \uce58\ub8cc\uc81c\ub97c \ud658\uc790\uc5d0\uac8c \uc9c1\uc811 \uc8fc\uc0ac\ud569\ub2c8\ub2e4. LNP\ub97c \ud1b5\ud574 \uc804\ub2ec\ub418\ub294 \ud658\uc0c1 RNA \ud0d1\uc7ac\uccb4(payload)\ub294 \ud658\uc790 \uc790\uc2e0\uc758 T\uc138\ud3ec\ub85c \uc774\ub3d9\ud558\uc5ec \uccb4\ub0b4\uc5d0\uc11c CAR-T \uc138\ud3ec\uac00 \ub418\ub3c4\ub85d \uc7ac\ud504\ub85c\uadf8\ub798\ubc0d\ud569\ub2c8\ub2e4. \uccb4\ub0b4 \uc138\ud3ec \uc7ac\ud504\ub85c\uadf8\ub798\ubc0d(in vivo cell reprogramming)\uc73c\ub85c \uc54c\ub824\uc9c4 \uc774 \uc811\uadfc\ubc95\uc740 \uc804\ud1b5\uc801\uc778 \uc138\ud3ec \uce58\ub8cc\uc81c\uc640 \uad00\ub828\ub41c \uae34 \uc81c\uc870 \uacfc\uc815 \uc5c6\uc774 \uc678\ub798 \ud658\uacbd\uc5d0\uc11c \ud22c\uc5ec\ub420 \uc218 \uc788\ub294 \uc7a0\uc7ac\ub825\uc744 \uac00\uc9c0\uace0 \uc788\uc2b5\ub2c8\ub2e4.<br \/><br \/><\/p>\n\n<figure><img decoding=\"async\" class=\"aligncenter\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/03\/pexels-gustavo-fring-8770717-1024x683.jpg\" alt=\"\" \/><\/figure>\n\n<h3 class=\"wp-block-heading\" style=\"text-align: center;\"><br \/>\uc5b4\ub5a4 \uc9c8\ubcd1\uc744 \uce58\ub8cc\ud560 \uc218 \uc788\ub098?<\/h3>\n\n<p class=\"wp-block-paragraph\">ORN-252\ub294 \uba74\uc5ed \uccb4\uacc4\uac00 \uc778\uccb4 \uc790\uc2e0\uc758 \uc870\uc9c1\uc744 \uc798\ubabb \uacf5\uaca9\ud558\ub294 \uc0c1\ud0dc\uc778 B\uc138\ud3ec \uc8fc\ub3c4 \uc790\uac00\uba74\uc5ed \uc9c8\ud658\uc744 \uce58\ub8cc\ud558\uae30 \uc704\ud574 \uac1c\ubc1c\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc608\ub85c\ub294 \uc804\uc2e0\uc131 \ud64d\ubc18\uc131 \ub8e8\ud478\uc2a4(systemic lupus erythematosus, SLE)\uc640 \ub958\ub9c8\ud2f0\uc2a4 \uad00\uc808\uc5fc(rheumatoid arthritis)\uc774 \uc788\uc73c\uba70, \ub458 \ub2e4 \ube44\uc815\uc0c1\uc801\uc778 B\uc138\ud3ec \ud65c\ub3d9\uc744 \uc218\ubc18\ud569\ub2c8\ub2e4. CAR-T \uc138\ud3ec\ub97c \uc0ac\uc6a9\ud558\uc5ec \uc774\ub7ec\ud55c \ubb38\uc81c\uac00 \uc788\ub294 B\uc138\ud3ec\ub97c \uc120\ud0dd\uc801\uc73c\ub85c \uc81c\uac70\ud568\uc73c\ub85c\uc368 ORN-252\ub294 \uc9c8\ubcd1 \uacfc\uc815\uc744 \uadf8 \uadfc\uc6d0\uc9c0\uc5d0\uc11c \ucc28\ub2e8\ud558\ub294 \uac83\uc744 \ubaa9\ud45c\ub85c \ud569\ub2c8\ub2e4. \uc77c\ubd80 \uc5f0\uad6c\uc790\ub4e4\uc740 \uc774 \uba54\ucee4\ub2c8\uc998\uc774 \uc7a0\uc7ac\uc801\uc778 \uc7a5\uae30 \uba74\uc5ed \uccb4\uacc4 \uc7ac\uc124\uc815\uc744 \uc81c\uacf5\ud55c\ub2e4\uace0 \uc124\uba85\ud588\uc9c0\ub9cc, \uc774\ub294 \uc784\uc0c1 \uc2dc\ud5d8\uc744 \ud1b5\ud574 \ud655\uc778\ub418\uc5b4\uc57c \ud569\ub2c8\ub2e4.<\/p>\n\n<h2 class=\"wp-block-heading\" style=\"text-align: center;\"><br \/>\uc77c\ub77c\uc774 \ub9b4\ub9ac\uac00 \uc9c0\uae08 \uc774 \uc6c0\uc9c1\uc784\uc744 \ubcf4\uc774\ub294 \uc774\uc720\ub294 \ubb34\uc5c7\uc778\uac00?<\/h2>\n\n<h3 class=\"wp-block-heading\" style=\"text-align: center;\">\uc790\uac00\uba74\uc5ed \uc9c8\ud658 \uc2dc\uc7a5<\/h3>\n\n<p class=\"wp-block-paragraph\" data-path-to-node=\"61\">\uc790\uac00\uba74\uc5ed \uc9c8\ud658\uc740 \uc804 \uc138\uacc4\uc801\uc73c\ub85c \uc218\uc5b5 \uba85\uc758 \uc0ac\ub78c\ub4e4\uc5d0\uac8c \uc601\ud5a5\uc744 \ubbf8\uce58\uba70 \ud604\ub300 \uc758\ud559\uc5d0\uc11c \ucda9\uc871\ub418\uc9c0 \uc54a\uc740 \uc758\ub8cc \uc218\uc694\uac00 \uac00\uc7a5 \ud070 \ubd84\uc57c \uc911 \ud558\ub098\uc785\ub2c8\ub2e4. \ub2e8\uc77c\ud074\ub860 \ud56d\uccb4(monoclonal antibodies) \ubc0f \uba74\uc5ed\uc5b5\uc81c\uc81c(immunosuppressive drugs)\ub97c \ud3ec\ud568\ud55c \ud604\uc7ac\uc758 \uce58\ub8cc\ubc95\uc740 \uc99d\uc0c1\uc744 \uad00\ub9ac\ud558\uace0 \uc9c8\ubcd1 \uc9c4\ud589\uc744 \ub2a6\ucd94\ub294 \ub370 \ub3c4\uc6c0\uc774 \ub420 \uc218 \uc788\uc9c0\ub9cc, \uae30\uc800\uc758 \uba74\uc5ed \uae30\ub2a5 \uc7a5\uc560\ub97c \uc601\uad6c\uc801\uc778 \ubc29\uc2dd\uc73c\ub85c \ud574\uacb0\ud558\ub294 \uacbd\uc6b0\ub294 \ub4dc\ubb45\ub2c8\ub2e4. \ud658\uc790\ub4e4\uc740 \uc885\uc885 \ud3c9\uc0dd \uce58\ub8cc\ub97c \ud544\uc694\ub85c \ud558\uba70 \uc2dc\uac04\uc774 \uc9c0\ub0a8\uc5d0 \ub530\ub77c \ubc18\uc751\uc774 \uac10\uc18c\ud558\ub294 \uac83\uc744 \uacbd\ud5d8\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n<p data-path-to-node=\"62\">ORN-252\uc640 \uac19\uc740 \uccb4\ub0b4 \uc138\ud3ec \uce58\ub8cc\uc81c\ub294 \ub354 \uc9c0\uc18d\uc801\uc778 \uacb0\uacfc\uc758 \uc7a0\uc7ac\ub825\uc744 \uac00\uc9c4 \uba54\ucee4\ub2c8\uc998\uc801\uc73c\ub85c \ub2e4\ub978 \uc635\uc158\uc744 \uc81c\uacf5\ud569\ub2c8\ub2e4. \uc774\ub85c \uc778\ud574 \uc790\uac00\uba74\uc5ed \ubd84\uc57c\ub294 \uae30\uc874 \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c(biologics)\uc5d0 \uc774\uc740 \ucc28\uc138\ub300 \uce58\ub8cc\uc81c\ub97c \ucc3e\ub294 \uc8fc\uc694 \uc81c\uc57d \ud68c\uc0ac\ub4e4\uc5d0\uac8c \uc810\uc810 \ub354 \ub9e4\ub825\uc801\uc73c\ub85c \ub2e4\uac00\uc624\uace0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n<h3 class=\"wp-block-heading\" style=\"text-align: center;\">\uc81c\ud488\uc774 \uc544\ub2cc \ud50c\ub7ab\ud3fc<\/h3>\n\n<p class=\"wp-block-paragraph\" data-path-to-node=\"64\">\uc77c\ub77c\uc774 \ub9b4\ub9ac\ub294 \ub2e8\uc21c\ud788 \uc57d\ubb3c \ud558\ub098\ub97c \uc778\uc218\ud558\ub294 \uac83\uc774 \uc544\ub2d9\ub2c8\ub2e4. ORN-252\uc758 \uae30\ubc18\uc774 \ub418\ub294 oRNA-LNP \uccb4\ub0b4 \uc7ac\ud504\ub85c\uadf8\ub798\ubc0d \ud50c\ub7ab\ud3fc\uc740 \uad11\ubc94\uc704\ud558\uac8c \uc801\uc6a9\ub420 \uc218 \uc788\ub3c4\ub85d \uc124\uacc4\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc774\ub860\uc801\uc73c\ub85c \ub3d9\uc77c\ud55c \uae30\uc220 \uae30\ubc18\uc774 \uc885\uc591\ud559(oncology), \ud76c\uadc0 \uc720\uc804 \uc9c8\ud658 \ubc0f \ud45c\uc801 \uc138\ud3ec \uc7ac\ud504\ub85c\uadf8\ub798\ubc0d\uc774 \uc720\uc775\ud560 \uc218 \uc788\ub294 \ub2e4\ub978 \uc601\uc5ed\uc758 \uce58\ub8cc\uc81c\ub97c \uac1c\ubc1c\ud558\ub294 \ub370 \uc801\uc6a9\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc5ec\uae30\uc5d0\ub294 RNA \ub3c4\uad6c\uac00 \uc138\ud3ec \ud589\ub3d9 \ubc0f \ubd84\ud654\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce58\ub294 \ub370 \uc810\uc810 \ub354 \ub9ce\uc774 \uc0ac\uc6a9\ub418\uace0 \uc788\ub294 \uc904\uae30\uc138\ud3ec \uc5f0\uad6c\uc640 \uc778\uc811\ud55c \uc751\uc6a9 \ubd84\uc57c\uac00 \ud3ec\ud568\ub429\ub2c8\ub2e4.<\/p>\n<p data-path-to-node=\"65\">\uc804\uc784\uc0c1 \uac80\uc99d \ud6c4 \ub300\uaddc\ubaa8 \uc784\uc0c1 \uc2dc\ud5d8 \uc774\uc804\uc5d0 \uc624\ub974\ub098\ub97c \uc774 \ub2e8\uacc4\uc5d0\uc11c \uc778\uc218\ud568\uc73c\ub85c\uc368 \uc77c\ub77c\uc774 \ub9b4\ub9ac\ub294 \uc131\uc219\ud55c \ud50c\ub7ab\ud3fc\uc5d0 \ub300\ud55c \uc811\uadfc \uad8c\ud55c\uc744 \uc5bb\ub294 \ub3d9\uc2dc\uc5d0 \ucd08\uae30 \uacfc\ud559\uc801 \ubc1c\uacac\uc758 \uac00\uc7a5 \uc704\ud5d8\ud55c \ub2e8\uacc4\ub97c \ud53c\ud569\ub2c8\ub2e4.<\/p>\n\n<h2 class=\"wp-block-heading\" style=\"text-align: center;\"><br \/>\uc774\uac83\uc740 \ub354 \uad11\ubc94\uc704\ud55c \uc0b0\uc5c5\uc758 \uadf8\ub9bc\uc5d0 \uc5b4\ub5bb\uac8c \ubd80\ud569\ud558\ub294\uac00?<\/h2>\n\n<p class=\"wp-block-paragraph\" data-path-to-node=\"67\">\uc77c\ub77c\uc774 \ub9b4\ub9ac\ub9cc\uc774 \uc774 \ubc29\ud5a5\uc73c\ub85c \uc6c0\uc9c1\uc774\ub294 \uc720\uc77c\ud55c \uc8fc\uc694 \uc81c\uc57d \ud68c\uc0ac\ub294 \uc544\ub2d9\ub2c8\ub2e4. \uc9c0\ub09c \uba87 \ub144 \ub3d9\uc548 \ub2e4\uc218\uc758 \ub300\uaddc\ubaa8 \uc870\uc9c1\uc774 \uccb4\ub0b4 CAR-T \uae30\uc220\uc5d0 \uc0c1\ub2f9\ud55c \ud22c\uc790\ub97c \ud588\uc2b5\ub2c8\ub2e4.<\/p>\n<p data-path-to-node=\"68\">Gilead Sciences\ub294 \uc57d 3\uc5b5 5\ucc9c\ub9cc \ub2ec\ub7ec\uc5d0 Interius BioTherapeutics\ub97c \uc778\uc218\ud588\uc2b5\ub2c8\ub2e4. AbbVie\ub294 \ucd5c\ub300 21\uc5b5 \ub2ec\ub7ec\uc5d0 Capstan Therapeutics\ub97c \ub9e4\uc785\ud588\uc2b5\ub2c8\ub2e4. Bristol Myers Squibb\uc740 Orbital Therapeutics\uc5d0 15\uc5b5 \ub2ec\ub7ec\ub97c \ud22c\uc790\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n<p data-path-to-node=\"69\">\uc885\ud569\ud574\ubcf4\uba74, \uc774\ub7ec\ud55c \uac70\ub798\ub4e4\uc740 \uccb4\ub0b4 \uc138\ud3ec \uce58\ub8cc\uc81c\uac00 \ud2c8\uc0c8 \uc5f0\uad6c \uac1c\ub150\uc5d0\uc11c \uae00\ub85c\ubc8c \uc81c\uc57d \uc0b0\uc5c5\uc758 \uc8fc\ub958 \uc804\ub7b5\uc801 \uc6b0\uc120\uc21c\uc704\ub85c \uc774\ub3d9\ud588\uc74c\uc744 \ub098\ud0c0\ub0c5\ub2c8\ub2e4. \uc77c\ub77c\uc774 \ub9b4\ub9ac\uc758 \uc624\ub974\ub098 \uc778\uc218\ub294 \uc774 \uacbd\uc7c1\uc801\uc778 \uacf5\uac04\uc73c\ub85c\uc758 \uc9c4\uc785\uc744 \ud655\uc778\ud558\uba70 \uc774 \uae30\uc220\uc774 \ucc28\uc138\ub300 \uc758\ud559\uc758 \uacb0\uc815\uc801\uc778 \ud2b9\uc9d5\uc774 \ub420 \uc218 \uc788\ub2e4\ub294 \ub354 \ub113\uc740 \uc0b0\uc5c5\uc801 \ubbff\uc74c\uc744 \ubc18\uc601\ud569\ub2c8\ub2e4.<\/p>\n<p data-path-to-node=\"70\">\uad6d\uc81c\uc801\uc73c\ub85c\ub3c4 \uc774 \ubd84\uc57c\uc758 \uc5f0\uad6c \ud65c\ub3d9\uc774 \ud655\ub300\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc911\uad6d\uc5d0\uc11c\ub294 \uc57d 19\uac1c\uc758 \ud68c\uc0ac\uac00 \ubc14\uc774\ub7ec\uc2a4 \ubca1\ud130(viral vector) \ubc0f LNP \uae30\ubc18 \uc804\ub2ec \ubc29\ubc95\uc744 \ubaa8\ub450 \uc0ac\uc6a9\ud558\uc5ec \uccb4\ub0b4 CAR-T \ud504\ub85c\uadf8\ub7a8\uc744 \uac1c\ubc1c\ud558\uace0 \uc788\ub294 \uac83\uc73c\ub85c \ubcf4\uace0\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ud504\ub85c\uadf8\ub7a8 \uc911 \uc77c\ubd80\ub294 \ucd08\uae30 \uc784\uc0c1 \ud14c\uc2a4\ud2b8\ub97c \uc2dc\uc791\ud588\uc2b5\ub2c8\ub2e4. Hongxin Bio\ub77c\ub294 \ud55c \ud68c\uc0ac\ub294 \uc804\uc784\uc0c1 \ub8e8\ud478\uc2a4 \ubaa8\ub378\uc5d0\uc11c 60%\uc758 T\uc138\ud3ec \uc7ac\ud504\ub85c\uadf8\ub798\ubc0d \ube44\uc728\uacfc \uc8fc\ubaa9\ud560 \ub9cc\ud55c B\uc138\ud3ec \uc81c\uac70\ub97c \ubcf4\uace0\ud588\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uacb0\uacfc\ub294 \uc608\ube44\uc801\uc774\uae34 \ud558\uc9c0\ub9cc \uc774 \uc811\uadfc\ubc95\uc5d0 \ub300\ud55c \uc138\uacc4\uc801\uc778 \uad00\uc2ec\uc758 \uaddc\ubaa8\ub97c \uac15\uc870\ud569\ub2c8\ub2e4.<\/p>\n\n<h2 class=\"wp-block-heading\" style=\"text-align: center;\"><br \/>\ub2e4\uc74c \ub2e8\uacc4\ub294 \ubb34\uc5c7\uc778\uac00?<\/h2>\n\n<figure><img decoding=\"async\" class=\"aligncenter\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/03\/pexels-shvetsa-3845652-1024x683.jpg\" alt=\"\" \/><\/figure>\n\n<p class=\"wp-block-paragraph\" data-path-to-node=\"72\">2026\ub144\uc740 \uccb4\ub0b4 CAR-T \ubd84\uc57c\uc5d0\uc11c \uc911\uc694\ud55c \ud55c \ud574\uac00 \ub420 \uac83\uc73c\ub85c \uc608\uc0c1\ub418\uba70, ORN-252\ub97c \ud3ec\ud568\ud55c \uc5ec\ub7ec \ud504\ub85c\uadf8\ub7a8\uc774 \ucd5c\ucd08 \uc778\uccb4 \ub300\uc0c1 \uc5f0\uad6c(first-in-human studies)\uc5d0\uc11c \ucd08\uae30 \uc784\uc0c1 \ub370\uc774\ud130\ub97c \uc0dd\uc131\ud560 \uac83\uc73c\ub85c \uae30\ub300\ub429\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uacb0\uacfc\ub294 \uc804\uc784\uc0c1 \uc5f0\uad6c\uc5d0\uc11c \ubcf4\uc778 \uc720\ub9dd\ud55c \uc2e0\ud638\uac00 \ud658\uc790\uc5d0\uac8c \uc758\ubbf8 \uc788\uace0 \uce21\uc815 \uac00\ub2a5\ud55c \uc774\uc810\uc73c\ub85c \uc804\ud658\ub418\ub294\uc9c0 \uc5ec\ubd80\ub97c \uacb0\uc815\ud558\ub294 \ub370 \uc911\uc694\ud560 \uac83\uc785\ub2c8\ub2e4.<\/p>\n<p data-path-to-node=\"73\">\ubbf8\uad6d \uc2dd\ud488\uc758\uc57d\uad6d(U.S. Food and Drug Administration) \ubc0f \uc720\ub7fd \uc758\uc57d\ud488\uccad(European Medicines Agency)\uc744 \ud3ec\ud568\ud55c \uaddc\uc81c \uae30\uad00\ub4e4\uc740 \uc774\ub7ec\ud55c \uce58\ub8cc\ubc95\uc774 \uc5b4\ub5bb\uac8c \ud3c9\uac00\ub418\uace0 \uc2b9\uc778\ub418\ub294\uc9c0\ub97c \ud615\uc131\ud558\ub294 \ub370 \uc911\uc694\ud55c \uc5ed\ud560\uc744 \ud560 \uac83\uc785\ub2c8\ub2e4. \uc774 \uc0c8\ub85c\uc6b4 \uc885\ub958\uc758 \uce58\ub8cc\ubc95\uc5d0 \ub300\ud55c \uc99d\uac70 \ud45c\uc900\uc774 \uacc4\uc18d \ubc1c\uc804\ud568\uc5d0 \ub530\ub77c, 2026\ub144 \uc774\ud6c4\uc5d0 \ub098\uc624\ub294 \uc784\uc0c1 \ub370\uc774\ud130\ub294 \uce58\ub8cc \uc804\ub7b5\uc73c\ub85c\uc11c \uccb4\ub0b4 \uc138\ud3ec \uc7ac\ud504\ub85c\uadf8\ub798\ubc0d\uc758 \uac00\ub2a5\uc131\uacfc \ud55c\uacc4\ub97c \ubaa8\ub450 \uc815\uc758\ud558\ub294 \ub370 \ub3c4\uc6c0\uc774 \ub420 \uac83\uc785\ub2c8\ub2e4.<\/p>\n<p data-path-to-node=\"74\">\uc77c\ub77c\uc774 \ub9b4\ub9ac\uc758 \uc624\ub974\ub098 \ud14c\ub77c\ud4e8\ud2f1\uc2a4 \uc778\uc218\ub294 \ud575\uc2ec\uc801\uc73c\ub85c \uc138\ud3ec \uae30\ubc18 \uce58\ub8cc\uc81c\uac00 \uc81c\uc870\ub418\uace0 \uc804\ub2ec\ub418\ub294 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