{"id":25246,"date":"2026-05-19T13:27:21","date_gmt":"2026-05-19T05:27:21","guid":{"rendered":"https:\/\/stemcell-malaysia.com\/?page_id=25246"},"modified":"2026-05-19T13:27:23","modified_gmt":"2026-05-19T05:27:23","slug":"crohns-disease","status":"publish","type":"page","link":"https:\/\/stemcell-malaysia.com\/ko\/conditions\/crohns-disease\/","title":{"rendered":"\ud06c\ub860\ubcd1 \uc904\uae30\uc138\ud3ec \uce58\ub8cc\u3163\uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c \ud6a8\uacfc\uac00 \ub5a8\uc5b4\uc84c\uc744 \ub54c\uc758 \ub610 \ub2e4\ub978 \uc120\ud0dd\uc9c0"},"content":{"rendered":"\n

\ud06c\ub860\ubcd1 \uc904\uae30\uc138\ud3ec \uce58\ub8cc\u3163\uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c \ud6a8\uacfc\uac00 \ub5a8\uc5b4\uc84c\uc744 \ub54c\uc758 \ub610 \ub2e4\ub978 \uc120\ud0dd\uc9c0<\/h1>\n\n\n
\n
\"\uc778\uccb4
\ud55c\uad6d\uc5d0\uc11c \ud06c\ub860\ubcd1\uc740 \ube60\ub974\uac8c \uc99d\uac00\ud558\ub294 \ub9cc\uc131 \uc5fc\uc99d\uc131 \uc7a5\uc9c8\ud658\uc774\uba70, \ud3c9\uade0 \uc9c4\ub2e8 \uc5f0\ub839\uc740 25\uc138 \uc804\ud6c4\uc785\ub2c8\ub2e4.<\/figcaption><\/figure>\n<\/div>\n\n\n

\uc544\uce68\uc5d0 \ub208\uc744 \ub728\uc790\ub9c8\uc790 \uc624\ub298 \ud654\uc7a5\uc2e4\uc744 \uba87 \ubc88 \uac00\uac8c \ub420\uc9c0 \uac00\ub2a0\ud558\ub294 \uc2b5\uad00. \uc57d\uc18d \uc7a5\uc18c\uc5d0 \uac00\uae30 \uc804 \ud654\uc7a5\uc2e4 \uc704\uce58\ubd80\ud130 \ud655\uc778\ud558\ub294 \uc2b5\uad00. \uc678\uc2dd \uc804\ub0a0\ubd80\ud130 \uc2dd\ub2e8\uc744 \uc2e0\uc911\ud788 \uc870\uc808\ud558\ub294 \uc77c\uc0c1. \ud06c\ub860\ubcd1\uacfc \uc624\ub798 \ud568\uaed8\ud574 \uc624\uc2e0 \ubd84\ub4e4\uc774\ub77c\uba74 \uc775\uc219\ud55c \ud48d\uacbd\uc77c \uac83\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

\ud55c\uad6d\uc5d0\uc11c \ud06c\ub860\ubcd1 \ud658\uc790\ub294 \uc57d 25,000~30,000\uba85\uc73c\ub85c \ucd94\uc815\ub418\uba70, \ub9e4\ub144 6~10%\uc529 \ube60\ub974\uac8c \uc99d\uac00\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ud3c9\uade0 \uc9c4\ub2e8 \uc5f0\ub839\uc740 25\uc138 \uc804\ud6c4\ub85c, \ud559\uc5c5\uc774\ub098 \uc9c1\uc7a5 \uc0dd\ud65c\uc744 \ub9c9 \uc2dc\uc791\ud560 \uc988\uc74c\uc5d0 \uc9c4\ub2e8\ubc1b\ub294 \ubd84\uc774 \ub9ce\uc2b5\ub2c8\ub2e4. 5-ASA \uc81c\uc81c\ubd80\ud130 \uc2dc\uc791\ud558\uc5ec \uc2a4\ud14c\ub85c\uc774\ub4dc, \uba74\uc5ed\uc870\uc808\uc81c(\uc544\uc790\ud2f0\uc624\ud504\ub9b0 \ub4f1), \uadf8\ub9ac\uace0 \uc778\ud50c\ub9ad\uc2dc\ub9d9\u00b7\uc544\ub2ec\ub9ac\ubb34\ub9d9\u00b7\uc6b0\uc2a4\ud14c\ud0a4\ub204\ub9d9\u00b7\ubca0\ub3cc\ub9ac\uc8fc\ub9d9 \uac19\uc740 \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\ub85c \uc774\uc5b4\uc9c0\ub294 \ud45c\uc900 \uce58\ub8cc \ub2e8\uacc4\ub294 \ub9ce\uc740 \ubd84\uc5d0\uac8c \uc774\ubbf8 \uc775\uc219\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

\ud55c\uad6d\uc740 2012\ub144\uc5d0 \uc790\uac00 \uc9c0\ubc29\uc720\ub798 \uc911\uac04\uc5fd \uc904\uae30\uc138\ud3ec \uc81c\ud488\uc778 \ud050\ud53c\uc2a4\ud15c(Cupistem)\uc774 \ud06c\ub860\ubcd1 \ud56d\ubb38\uc8fc\uc704\ub204\uacf5 \uce58\ub8cc\uc81c\ub85c \ud5c8\uac00\ubc1b\uc740, \uc904\uae30\uc138\ud3ec \uce58\ub8cc\ub77c\ub294 \uac1c\ub150 \uc790\uccb4\uc5d0 \ube44\uad50\uc801 \uc775\uc219\ud55c \uc2dc\uc7a5\uc785\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \ud050\ud53c\uc2a4\ud15c\uc5d0 \ucda9\ubd84\ud788 \ubc18\uc751\ud558\uc9c0 \uc54a\uc740 \ud658\uc790, \ub204\uacf5\uc774 \uc544\ub2cc \ub8e8\uba58(\uc7a5\uad00 \ub0b4\uac15)\uc5d0 \ud65c\ub3d9\uc131 \uc5fc\uc99d\uc774 \uc9c0\uc18d\ub418\ub294 \ud658\uc790, \uc5ec\ub7ec \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\uac00 \ucc28\ub840\ub85c \ud6a8\uacfc\ub97c \uc783\uc740 \ud658\uc790\uac00 \ub2e4\uc74c \ub2e8\uacc4\ub85c \ubb34\uc5c7\uc744 \uc120\ud0dd\ud560 \uc218 \uc788\ub294\uc9c0\uc5d0 \ub300\ud55c \uc815\ubcf4\ub294 \uc758\uc678\ub85c \uc801\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

\uc774 \uae00\uc740 \ubc14\ub85c \uadf8\ub7ec\ud55c \uc0c1\ud669\uc5d0 \uacc4\uc2e0 \ubd84\ub4e4\uc744 \uc704\ud574 \uc791\uc131\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ub3d9\uc885 \uc81c\ub300\uc720\ub798 \uc911\uac04\uc5fd \uc904\uae30\uc138\ud3ec(allogeneic umbilical cord MSC)\ub294 \ud050\ud53c\uc2a4\ud15c\uacfc\ub294 \ub2e4\ub978 \uc138\ud3ec \ucd9c\ucc98\ub97c \uc0ac\uc6a9\ud558\ub294 \uc811\uadfc\ubc95\uc73c\ub85c, \uc720\ub7fd\uc5d0\uc11c\ub294 darvadstrocel(\uc0c1\ud488\uba85 Alofisel)\uc774 2018\ub144\uc5d0 \uc815\uc2dd \ud5c8\uac00\ub97c \ubc1b\uc558\uc2b5\ub2c8\ub2e4. \uc800\ud76c\ub294 \ub9d0\ub808\uc774\uc2dc\uc544\uc5d0\uc11c 7\ub144 \uc774\uc0c1, 200\uba85 \uc774\uc0c1\uc758 \ud658\uc790\ubd84\uaed8 \ub3d9\uc885 \uc81c\ub300\uc720\ub798 MSC \uce58\ub8cc\ub97c \uc9c4\ud589\ud574 \uc654\uc2b5\ub2c8\ub2e4. \uc774 \uae00\uc5d0\uc11c\ub294 \uc784\uc0c1 \ub370\uc774\ud130\uac00 \uc5b4\ub514\uae4c\uc9c0 \uc785\uc99d\ub418\uc5c8\uace0 \uc5b4\ub514\ubd80\ud130\ub294 \ubd88\ud655\uc2e4\ud55c\uc9c0\ub97c \uc194\uc9c1\ud558\uac8c \uc815\ub9ac\ud558\uaca0\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

<\/div>\n\n\n\n

\ubaa9\ucc28<\/mark><\/h2>\n\n\n
  1. \ud06c\ub860\ubcd1\uc774 \uc798 \uce58\uc720\ub418\uc9c0 \uc54a\ub294 \ub450 \uac00\uc9c0 \uc774\uc720<\/a>
      <\/ol><\/li>
    1. \ud45c\uc900 \uce58\ub8cc\uac00 \ubd80\ub52a\ud788\ub294 \ud55c\uacc4<\/a>
        <\/ol><\/li>
      1. \ud06c\ub860\ubcd1\uc5d0 \ub300\ud55c \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc758 \uc791\uc6a9 \ubc29\uc2dd<\/a>
          <\/ol><\/li>
        1. \ud06c\ub860\ubcd1 \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc758 \uc784\uc0c1\uc2dc\ud5d8 \uadfc\uac70<\/a>
            <\/ol><\/li>
          1. \uc790\uac00\uc138\ud3ec\uc640 \ub3d9\uc885 \uc81c\ub300\uc720\ub798 MSC\uc758 \ucc28\uc774<\/a>
              <\/ol><\/li>
            1. \ud06c\ub860\ubcd1 \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uac00 \uc801\ud569\ud55c \ud658\uc790\uc640 \uadf8\ub807\uc9c0 \uc54a\uc740 \ud658\uc790<\/a>
                <\/ol><\/li>
              1. \ud658\uc790\ubd84\uc758 \uacbd\uacfc \uc0ac\ub840<\/a>
                  <\/ol><\/li>
                1. \ud06c\ub860\ubcd1 \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc758 \uc704\ud5d8\uacfc \uc815\uc9c1\ud55c \ud55c\uacc4<\/a>
                    <\/ol><\/li>
                  1. \ud06c\ub860\ubcd1 \uc904\uae30\uc138\ud3ec \uce58\ub8cc \uc790\uc8fc \ubb3b\ub294 \uc9c8\ubb38<\/a><\/li>
                  2. \ub2e4\uc74c \ub2e8\uacc4\ub97c \uace0\ubbfc\ud558\uace0 \uacc4\uc2e0 \ubd84\uaed8<\/a><\/li>
                  3. \ucc38\uace0\ubb38\ud5cc<\/a><\/li><\/ol><\/div>\n\n\n
                    <\/div>\n\n\n\n

                    \ud06c\ub860\ubcd1\uc774 \uc798 \uce58\uc720\ub418\uc9c0 \uc54a\ub294 \ub450 \uac00\uc9c0 \uc774\uc720<\/mark><\/h2>\n\n\n\n

                    \ub9cc\uc131 \uc5fc\uc99d\uc774 \uc7a5\ubcbd \uae4a\uc740 \uacf3\uae4c\uc9c0 \uc190\uc0c1\uc2dc\ud0a4\ub294 \uba54\ucee4\ub2c8\uc998<\/h3>\n\n\n\n

                    \ud06c\ub860\ubcd1\uc740 \ubcf8\ub798 \uc678\ubd80 \uce68\uc785\uc790\ub85c\ubd80\ud130 \ubab8\uc744 \ubcf4\ud638\ud574\uc57c \ud560 \uba74\uc5ed \uc2dc\uc2a4\ud15c\uc774 \uc790\uc2e0\uc758 \uc7a5 \uc870\uc9c1\uc744 \uc798\ubabb \uacf5\uaca9\ud558\ub294 \ub9cc\uc131 \uc5fc\uc99d\uc131 \uc7a5\uc9c8\ud658\uc785\ub2c8\ub2e4. \uc785\uc5d0\uc11c \ud56d\ubb38\uae4c\uc9c0 \uc5b4\ub514\uc5d0\ub4e0 \uc0dd\uae38 \uc218 \uc788\uc9c0\ub9cc, \uac00\uc7a5 \ud754\ud55c \ubc1c\uc0dd \ubd80\uc704\ub294 \ud68c\uc7a5 \ub9d0\ub2e8(\uc18c\uc7a5\uc758 \ub05d)\uacfc \uc0c1\ud589\uacb0\uc7a5\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ud06c\ub860\ubcd1\uc758 \ud2b9\uc9d5\uc801\uc778 \uc810\uc740 \uc5fc\uc99d\uc774 \uc7a5\uc758 \ud45c\uba74 \uc810\ub9c9\uc5d0\ub9cc \uba38\ubb3c\uc9c0 \uc54a\uace0 \uadfc\uc721\uce35\uc744 \uc9c0\ub098 \uac00\uc7a5 \ubc14\uae65\ucabd\uae4c\uc9c0 \ud30c\uace0\ub4e0\ub2e4\ub294 \uac83\uc785\ub2c8\ub2e4. \ud45c\uba74\ub9cc \ubd89\uc5b4\uc9c0\ub294 \uac83\uc774 \uc544\ub2c8\ub77c \uc7a5\ubcbd \uc804\uccb4\ub97c \uac00\ub85c\uc9c0\ub974\ub294 \uae4a\uc740 \uc5fc\uc99d\uc774 \uc77c\uc5b4\ub0a9\ub2c8\ub2e4. \ub2e8\uc21c\ud55c \ud56d\uc5fc\uc81c\ub9cc\uc73c\ub85c\ub294 \ub2ff\uc9c0 \uc54a\ub294 \uc774\uc720\uac00 \uc5ec\uae30\uc5d0 \uc788\uc2b5\ub2c8\ub2e4. \uc7a5\ubcbd\uc774 \ub450\uaebc\uc6cc\uc9c0\uace0 \ud1b5\ub85c\uac00 \uc881\uc544\uc9c0\uba74\uc11c \ubcf5\ud1b5, \uc124\uc0ac, \uccb4\uc911 \uac10\uc18c\uac00 \uc77c\uc0c1\uc744 \uc9c0\ubc30\ud558\uac8c \ub429\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uadf8\ub9ac\uace0 \ud55c \ucc28\ub840 \uc5fc\uc99d\uc774 \uac00\ub77c\uc549\uc558\ub2e4\uace0 \ud574\uc11c \uc870\uc9c1\uc774 \uc644\uc804\ud788 \uc6d0\ub798\ub300\ub85c \ub3cc\uc544\uac00\ub294 \uac83\uc740 \uc544\ub2d9\ub2c8\ub2e4. \uc7ac\ubc1c\ud560 \ub54c\ub9c8\ub2e4 \uc870\uae08\uc529 \uad6c\uc870\uc801 \uc190\uc0c1\uc774 \ub0a8\uace0, 20\ub144\u00b730\ub144\uc5d0 \uac78\uccd0 \ub204\uc801\ub429\ub2c8\ub2e4. \ud06c\ub860\ubcd1\uc774 \uc9c4\ud589\uc131 \uc9c8\ud658\uc778 \uc0dd\ubb3c\ud559\uc801 \uc774\uc720\uc774\uba70, \ucd5c\uadfc \uce58\ub8cc \ubaa9\ud45c\uac00 “\uc99d\uc0c1 \uc870\uc808”\uc5d0\uc11c “\uad6c\uc870\uc801 \uc9c4\ud589 \uc608\ubc29”\uc73c\ub85c \uc62e\uaca8\uac00\uace0 \uc788\ub294 \ubc30\uacbd\uc774\uae30\ub3c4 \ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \ub204\uacf5\uacfc \ud611\ucc29\uc774 \uc57d\uc73c\ub85c \uce58\ub8cc\ub418\uc9c0 \uc54a\ub294 \uc774\uc720<\/h3>\n\n\n\n

                    \uae4a\uc774 \uce68\ud22c\ud558\ub294 \uc5fc\uc99d\uc740 \ud06c\ub860\ubcd1 \ud2b9\uc720\uc758 \ub450 \uac00\uc9c0 \uae4c\ub2e4\ub85c\uc6b4 \ud569\ubcd1\uc99d\uc744 \ub9cc\ub4ed\ub2c8\ub2e4. \ub204\uacf5\uacfc \ud611\ucc29\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ub204\uacf5\uc740 \uc6d0\ub798 \uc5f0\uacb0\ub418\uc5b4\uc11c\ub294 \uc548 \ub418\ub294 \ubd80\uc704 \uc0ac\uc774\uc5d0 \ube44\uc815\uc0c1\uc801\uc778 \ud1b5\ub85c\uac00 \uc0dd\uae30\ub294 \uc0c1\ud0dc\ub97c \ub9d0\ud569\ub2c8\ub2e4. \uae4a\uc740 \uc5fc\uc99d\uc774 \uc7a5\ubcbd\uc744 \ub6ab\uace0, \ubab8\uc774 \uc0c1\ucc98\ub97c \ub2eb\uc73c\ub824\ub2e4\uac00 \uae68\ub057\ud558\uac8c \ubd09\ud569\ud558\uc9c0 \ubabb\ud574 \uc6b0\ud68c\ub85c\ub97c \ub9cc\ub4e4\uc5b4\ubc84\ub9b0 \uacb0\uacfc\uc785\ub2c8\ub2e4. \ud06c\ub860\ubcd1 \ud658\uc790\uc758 \uc57d 20~30%\uac00 \uc9c8\ubcd1 \uacbd\uacfc \uc911 \uc5b4\ub290 \uc2dc\uc810\uc5d0 \ud56d\ubb38\uc8fc\uc704 \ub18d\uc591\uc774\ub098 \ub204\uacf5\uc744 \uacbd\ud5d8\ud569\ub2c8\ub2e4. \uc2dc\ud2bc \ubc30\uc561, \ub204\uacf5 \uc808\uac1c\uc220, \ud53c\ube0c\ub9b0 \uae00\ub8e8, \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c \ubcd1\uc6a9 \ub4f1 \ub2e4\uc591\ud55c \ubc29\ubc95\uc774 \uc2dc\ub3c4\ub418\uc9c0\ub9cc, \ubcf5\uc7a1\ub204\uacf5\uc758 \uc644\uc804\ud55c \ud3d0\uc1c4\uc728\uc740 \uc5ec\uc804\ud788 \ub192\uc9c0 \uc54a\uace0, \uba87 \ub144\uc529 \uc2dc\ud2bc\uc744 \uc720\uc9c0\ud558\ub294 \uacbd\uc6b0\ub3c4 \ub4dc\ubb3c\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ud611\ucc29\uc740 \uc5fc\uc99d\uacfc \uce58\uc720\uac00 \ubc18\ubcf5\ub41c \ubd80\uc704\uc5d0 \ud749\ud130 \uc870\uc9c1(\uc12c\uc720\ud654\ub41c \ub2e8\ub2e8\ud55c \uc870\uc9c1)\uc774 \uc313\uc5ec \uc7a5\uc758 \ud1b5\ub85c\uac00 \ubb3c\ub9ac\uc801\uc73c\ub85c \uc881\uc544\uc9c0\ub294 \uc0c1\ud0dc\uc785\ub2c8\ub2e4. \uc2dd\ud6c4 \ubcf5\ud1b5, \uad6c\ud1a0, \uc7a5\ud3d0\uc0c9\uc758 \uc9d5\ud6c4\ub85c \ub098\ud0c0\ub0a9\ub2c8\ub2e4. \ud611\ucc29\uc774 \uc77c\uc815 \uc218\uc900 \uc774\uc0c1 \uc9c4\ud589\ub418\uba74 \uc57d\uc73c\ub85c\ub294 \ub2e4\uc2dc \ub113\uc5b4\uc9c0\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \ud06c\ub860\ubcd1\uc5d0\uc11c \uc7a5 \uc808\uc81c\uc220\uc774 \uac00\uc7a5 \ub9ce\uc774 \uc2dc\ud589\ub418\ub294 \uc774\uc720\uac00 \ubc14\ub85c \ud611\ucc29\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ub204\uacf5\ub3c4 \ud611\ucc29\ub3c4 \uba74\uc5ed\uc758 \ubb38\uc81c \uc704\uc5d0 “\uad6c\uc870\uc758 \ubb38\uc81c”\uac00 \uacb9\uccd0 \uc788\ub2e4\ub294 \uc810\uc774 \uacf5\ud1b5\uc810\uc785\ub2c8\ub2e4. \uc5fc\uc99d\uc744 \uc798 \ub2e4\uc2a4\ub9ac\ub294 \uc57d\uc774 \uc788\ub2e4 \ud574\ub3c4 \uc774\ubbf8 \ud615\uc131\ub41c \ub204\uacf5 \ud1b5\ub85c\ub97c \ub2eb\uc9c0 \ubabb\ud558\uba70, \uc774\ubbf8 \uad73\uc5b4\uc9c4 \ud611\ucc29\uc744 \ub2e4\uc2dc \ub113\ud788\uc9c0\ub3c4 \ubabb\ud569\ub2c8\ub2e4. \uc774 \uac04\uadf9\uc774 \ud06c\ub860\ubcd1\uc774 \uc7ac\uc0dd\uc758\ub8cc \uc5f0\uad6c\uc758 \uc8fc\uc694 \ub300\uc0c1\uc774 \ub41c \uc774\uc720\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \ud45c\uc900 \uce58\ub8cc\uac00 \ubd80\ub52a\ud788\ub294 \ud55c\uacc4<\/mark><\/h2>\n\n\n\n

                    \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\uac00 \uac00\uc838\uc628 \ubc1c\uc804\uacfc \uadf8 \ud55c\uacc4<\/h3>\n\n\n\n

                    \ud06c\ub860\ubcd1\uc758 \uc57d\ubb3c \uce58\ub8cc\ub294 \uc9c0\ub09c 20\ub144\uac04 \ud06c\uac8c \ubc1c\uc804\ud588\uc2b5\ub2c8\ub2e4. 1990\ub144\ub300 \ud6c4\ubc18\uc5d0 \ub4f1\uc7a5\ud55c \ud56dTNF-\u03b1 \ud56d\uccb4(\uc778\ud50c\ub9ad\uc2dc\ub9d9, \uc544\ub2ec\ub9ac\ubb34\ub9d9)\ub294 \uadf8\uc804\uae4c\uc9c0 \ub09c\uce58\uc131\uc73c\ub85c \uc5ec\uaca8\uc84c\ub358 \ub9ce\uc740 \uc911\ub4f1\ub3c4~\uc911\uc99d \ud658\uc790\ubd84\uaed8 \uad00\ud574\ub97c \uac00\uc838\uc654\uc2b5\ub2c8\ub2e4. \uc774\ud6c4 \uc7a5\uad00 \ud2b9\uc774\uc801\uc73c\ub85c \uc791\uc6a9\ud558\ub294 \ubca0\ub3cc\ub9ac\uc8fc\ub9d9, IL-12\/23\uc744 \ud45c\uc801\uc73c\ub85c \ud558\ub294 \uc6b0\uc2a4\ud14c\ud0a4\ub204\ub9d9, IL-23\ub9cc \ud45c\uc801\uc73c\ub85c \ud558\ub294 \ub9ac\uc0b0\ud0a4\uc8fc\ub9d9 \ub4f1 \uc0c8\ub85c\uc6b4 \uc791\uc6a9 \uae30\uc804\uc758 \uc57d\uc81c\uac00 \uc120\ud0dd\uc9c0\uc5d0 \ucd94\uac00\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uadf8\ub7fc\uc5d0\ub3c4 \ub370\uc774\ud130\uac00 \ubcf4\uc5ec\uc8fc\ub294 \ud604\uc2e4\uc740 \uac00\ud639\ud569\ub2c8\ub2e4. \uccab \ubc88\uc9f8 \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\uc5d0 \ub300\ud55c \uc77c\ucc28 \ubb34\ubc18\uc751(\uc804\ud600 \ud6a8\uacfc\uac00 \uc5c6\uc74c)\uc774 \ud658\uc790\uc758 \uc57d 30%\uc5d0\uc11c \ub098\ud0c0\ub0a9\ub2c8\ub2e4. \ud6a8\uacfc\ub97c \ubcf8 \ud658\uc790\ubd84 \uc911\uc5d0\uc11c\ub3c4 30~40%\uac00 \uc2dc\uac04\uc774 \uc9c0\ub098\uba74\uc11c \ud6a8\uacfc\uac00 \uc57d\ud574\uc9c0\ub294 \uc774\ucc28 \ubb34\ubc18\uc751\uc744 \uacbd\ud5d8\ud569\ub2c8\ub2e4. \ub9ce\uc740 \uacbd\uc6b0 \ubab8\uc774 \uc57d\uc81c\uc5d0 \ub300\ud55c \uc911\ud654 \ud56d\uccb4\ub97c \ub9cc\ub4e4\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uadf8\ub9ac\uace0 \ub450 \ubc88\uc9f8, \uc138 \ubc88\uc9f8 \uc57d\uc81c\ub85c \ubc14\uafd4\uac08\uc218\ub85d \ubc18\uc751\ub960\uc740 \uc810\ucc28 \ub5a8\uc5b4\uc9d1\ub2c8\ub2e4. \uc138 \ubc88\uc9f8 \uc774\ud6c4\uc758 \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\ub85c \uc9c0\uc18d\uc801\uc778 \uc784\uc0c1\uc801 \uad00\ud574\uc5d0 \ub3c4\ub2ec\ud560 \ud655\ub960\uc740 \uccab \ud22c\uc5ec \ub54c\uc5d0 \ube44\ud574 \ubd84\uba85\ud788 \ub0ae\uc544\uc9d1\ub2c8\ub2e4. JAK \uc5b5\uc81c\uc81c\ub294 \uc0c8\ub85c\uc6b4 \uc635\uc158\uc774\uc9c0\ub9cc \uac10\uc5fc\uacfc \ud608\uc804 \uc704\ud5d8\uc5d0 \ub300\ud55c \uaddc\uc81c \ub2f9\uad6d\uc758 \ud3c9\uac00\uac00 \uacc4\uc18d \uc9c4\ud589 \uc911\uc774\ub77c \ubaa8\ub4e0 \ud658\uc790\ubd84\uaed8 \uc801\ud569\ud558\ub2e4\uace0 \ub9d0\ud558\uae30\ub294 \uc5b4\ub835\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \ud06c\ub860\ubcd1 \uc218\uc220\uc774 \uac00\uc9c4 \uadfc\ubcf8\uc801 \ud55c\uacc4<\/h3>\n\n\n\n

                    \ud06c\ub860\ubcd1 \ud658\uc790\ubd84\uc758 \uc57d \uc808\ubc18\uc774 \uc9c4\ub2e8 \ud6c4 10\ub144 \uc774\ub0b4\uc5d0 \uc801\uc5b4\ub3c4 \ud55c \ubc88\uc758 \uc7a5 \uc808\uc81c\uc220\uc744 \ubc1b\uac8c \ub41c\ub2e4\uace0 \ubcf4\uace0\ub429\ub2c8\ub2e4. \ud611\ucc29, \ub204\uacf5, \uc57d\ubb3c \uc800\ud56d\uc131 \uc5fc\uc99d \ub4f1\uc5d0\uc11c \uc218\uc220\uc774 \uc801\uc808\ud55c \uc120\ud0dd\uc774 \ub418\ub294 \uc0c1\ud669\uc740 \ubd84\uba85\ud788 \uc874\uc7ac\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ud558\uc9c0\ub9cc \ud06c\ub860\ubcd1\uc758 \uc218\uc220\uc740 \ub2e4\ub978 \uc678\uacfc \uc9c8\ud658\uacfc \uacb0\uc815\uc801\uc73c\ub85c \ub2e4\ub978 \uc810\uc774 \uc788\uc2b5\ub2c8\ub2e4. \ubcd1\ubcc0 \ubd80\uc704\ub97c \uc808\uc81c\ud574\ub3c4 \uba74\uc5ed \uc774\uc0c1\uc774\ub77c\ub294 \uadfc\ubcf8 \uc6d0\uc778\uc740 \uadf8\ub300\ub85c \ub0a8\uc2b5\ub2c8\ub2e4. \ucd08\uae30 \uc218\uc220 \ud6c4 5\ub144 \uc774\ub0b4\uc5d0 \uc57d \uc808\ubc18\uc758 \ud658\uc790\ubd84\uc5d0\uc11c \ubb38\ud569\ubd80 \uadfc\ucc98\uc5d0 \uc7ac\ubc1c \uc18c\uacac\uc774 \ub098\ud0c0\ub0a9\ub2c8\ub2e4. \uc7ac\uc808\uc81c\ub97c \ubc18\ubcf5\ud558\uba74 \ub2f9\uc5f0\ud788 \ub0a8\ub294 \uc7a5\uc774 \uc9e7\uc544\uc9c0\uace0, \uadf9\ub2e8\uc801\uc778 \uacbd\uc6b0\uc5d0\ub294 \ub2e8\uc7a5 \uc99d\ud6c4\uad70\uc73c\ub85c \uc815\ub9e5 \uc601\uc591\uc5d0 \uc758\uc874\ud558\uac8c \ub418\ub294 \ubd84\ub3c4 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ub204\uacf5\uc5d0\uc11c\ub3c4 \uc218\uc220\uc801 \uad00\ub9ac\uc758 \ud55c\uacc4\ub294 \uba85\ud655\ud569\ub2c8\ub2e4. \ubcf5\uc7a1\ub204\uacf5\uc5d0 \ub300\ud55c \uc218\uc220 \uc131\uc801\uc740 \uacb0\ucf54 \ub192\uc9c0 \uc54a\uc73c\uba70, \uc7ac\ubc1c\uacfc \uc7ac\uc218\uc220\uc744 \ubc18\ubcf5\ud558\ub2e4\uac00 \uad04\uc57d\uadfc\uc744 \uc190\uc0c1\uc2dc\ucf1c \ubcc0\uc2e4\uae08\uc774\ub77c\ub294 \uc0c8\ub85c\uc6b4 \ubb38\uc81c\ub97c \uc548\uac8c \ub418\uae30\ub3c4 \ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc774\ub7ec\ud55c \uc784\uc0c1\uc801 \ud604\uc2e4\uc774, \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\uc5d0 \ub09c\uce58\ud654\ub41c \ud658\uc790\ubd84\uacfc \ubc18\ubcf5\ub418\ub294 \ub204\uacf5\uc5d0 \uc2dc\ub2ec\ub9ac\ub294 \ubd84\uc774 \uc7ac\uc0dd\uc758\ub8cc\uc5d0 \ub208\uc744 \ub3cc\ub9ac\ub294 \ubc30\uacbd\uc785\ub2c8\ub2e4. \ud45c\uc900 \uce58\ub8cc\ub97c \ubd80\uc815\ud558\ub294 \uac83\uc774 \uc544\ub2c8\ub77c “\uba74\uc5ed\uc758 \uc774\uc0c1 \uc790\uccb4\uc5d0 \uc791\uc6a9\ud558\ub294 \uc218\ub2e8\uc774 \uc788\ub2e4\uba74, \ud604\uc7ac \uce58\ub8cc\uc640 \ubcd1\ud589\ud574 \uc2dc\ub3c4\ud574 \ubcfc \uac00\uce58\uac00 \uc788\uc9c0 \uc54a\uc744\uae4c”\ub77c\ub294 \uc9c8\ubb38\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \ud06c\ub860\ubcd1\uc5d0 \ub300\ud55c \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc758 \uc791\uc6a9 \ubc29\uc2dd<\/mark><\/h2>\n\n\n
                    \n
                    \"\ud06c\ub860\ubcd1
                    \uc911\uac04\uc5fd \uc904\uae30\uc138\ud3ec\ub294 \ud06c\ub860\ubcd1\uc5d0 \ub300\ud574 \uc138 \uac00\uc9c0 \uacbd\ub85c\ub85c \uc791\uc6a9\ud55c\ub2e4\uace0 \uc54c\ub824\uc838 \uc788\uc73c\uba70, \uc774\ub294 \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\uc640 \uadfc\ubcf8\uc801\uc73c\ub85c \ub2e4\ub978 \ubc29\uc2dd\uc785\ub2c8\ub2e4.<\/figcaption><\/figure>\n<\/div>\n\n\n

                    \uba74\uc5ed\uc758 \ud3ed\uc8fc\ub97c “\ud558\ub958”\uac00 \uc544\ub2cc “\uc0c1\ub958”\uc5d0\uc11c \uc870\uc808<\/h3>\n\n\n\n

                    \uc911\uac04\uc5fd \uc904\uae30\uc138\ud3ec(MSC)\ub294 \uc77c\ubc18\uc801\uc778 \uc758\ubbf8\uc758 \ud56d\uc5fc\uc81c\uac00 \uc544\ub2d9\ub2c8\ub2e4. \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\uac00 TNF-\u03b1\ub098 IL-23 \uac19\uc740 \ud2b9\uc815 \uc0ac\uc774\ud1a0\uce74\uc778(\uc138\ud3ec \uc0ac\uc774 \uc815\ubcf4\ub97c \uc804\ub2ec\ud558\ub294 \ub2e8\ubc31\uc9c8)\uc744 “\ud558\ub958\uc5d0\uc11c” \ucc28\ub2e8\ud558\ub294 \ubc18\uba74, MSC\ub294 \uba74\uc5ed \uc138\ud3ec \uc790\uccb4\uc5d0 \uc791\uc6a9\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ud06c\ub860\ubcd1 \ud658\uc790\ubd84\uaed8 MSC\uac00 \ud22c\uc5ec\ub418\uba74 \uc138\ud3ec\ub294 \uc5fc\uc99d\uc774 \uc77c\uc5b4\ub098\uace0 \uc788\ub294 \ubd80\uc704\ub85c \uc774\ub3d9\ud558\uc5ec, \uadf8\uacf3\uc5d0\uc11c \uc5ec\ub7ec \uc885\ub958\uc758 \uc2e0\ud638 \ubd84\uc790\ub97c \ubd84\ube44\ud569\ub2c8\ub2e4. \uacf5\uaca9 \uc5ed\ud560\uc744 \ud558\ub294 T\uc138\ud3ec\uc640 \uc218\uc9c0\uc0c1\uc138\ud3ec\uc758 \ud65c\ub3d9\uc744 \uc5b5\uc81c\ud558\ub294 \ud55c\ud3b8, \ub9d0\ud558\uc790\uba74 “\ube0c\ub808\uc774\ud06c \uc5ed\ud560”\uc744 \ud558\ub294 \uc870\uc808T\uc138\ud3ec(Treg)\uc758 \uc99d\uac00\ub97c \ucd09\uc9c4\ud569\ub2c8\ub2e4. \uacf5\uaca9\uc744 \uac00\ub77c\uc549\ud788\uba74\uc11c \ub3d9\uc2dc\uc5d0 \uc5b5\uc81c\ud558\ub294 \ucabd\uc744 \ub298\ub9ac\ub294 \uc591\ubc29\ud5a5 \uc791\uc6a9\uc785\ub2c8\ub2e4. \ud2b9\uc815 \uc0ac\uc774\ud1a0\uce74\uc778\ub9cc \ucc28\ub2e8\ud558\ub294 \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\uc640\ub294 \uc791\ub3d9 \ubc29\uc2dd\uc774 \ubcf8\uc9c8\uc801\uc73c\ub85c \ub2e4\ub978 \ubd80\ubd84\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc774\uac83\uc774 \uc7a5\uae30\uc801\uc73c\ub85c \ub354 \ub098\uc740 \uacb0\uacfc\ub85c \uc774\uc5b4\uc9c0\ub294\uc9c0\ub294 \uc544\uc9c1 \uc5f0\uad6c \uc911\uc774\uc9c0\ub9cc, \uc5ec\ub7ec \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\uc5d0 \ubb34\ubc18\uc751\uc774 \ub41c \ud658\uc790\ubd84\ub3c4 MSC\uc5d0 \ubc18\uc751\ud558\ub294 \uc0ac\ub840\uac00 \ubcf4\uace0\ub418\ub294 \uac83\uc740 \uc774 \uae30\uc804 \ucc28\uc774\uac00 \ubc30\uacbd\uc5d0 \uc788\ub2e4\uace0 \uc5ec\uaca8\uc9d1\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \ub204\uacf5\uc758 \uad6d\uc18c \uc8fc\uc785\uc73c\ub85c \uc870\uc9c1 \uce58\uc720 \ucd09\uc9c4<\/h3>\n\n\n\n

                    MSC\uc758 \ub450 \ubc88\uc9f8 \uc791\uc6a9\uc740 \ud06c\ub860\ubcd1\uc758 \uac00\uc7a5 \uae4c\ub2e4\ub85c\uc6b4 \ud569\ubcd1\uc99d \uc911 \ud558\ub098\uc778 \ub204\uacf5\uc5d0 \ub300\ud55c \uac83\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    MSC\ub97c \ub204\uacf5 \ud1b5\ub85c\uc5d0 \uc9c1\uc811 \uc8fc\uc785\ud558\uba74, \uc138\ud3ec\ub294 \uad6d\uc18c\uc5d0\uc11c \uc131\uc7a5\uc778\uc790\uc640 \uc2e0\ud638 \ub2e8\ubc31\uc9c8\uc744 \ubd84\ube44\ud569\ub2c8\ub2e4. \uac74\uac15\ud55c \uc138\ud3ec\uc758 \uc774\ub3d9\uc744 \ucd09\uc9c4\ud558\uace0, \uba87 \ub144\uc774\ub098 \ub2eb\ud788\uc9c0 \uc54a\uc558\ub358 \ub204\uacf5 \uc8fc\ubcc0\uc5d0 \ub204\uc801\ub41c \uc5fc\uc99d \ud658\uacbd\uc744 \uac00\ub77c\uc549\ud788\uba70, \uc0c8\ub85c\uc6b4 \ubaa8\uc138\ud608\uad00 \ud615\uc131(\ud608\uad00 \uc2e0\uc0dd)\uc744 \uc9c0\uc6d0\ud569\ub2c8\ub2e4. \uadf8 \uacb0\uacfc\ub85c \uc624\ub7ab\ub3d9\uc548 \ub09c\uce58\uc600\ub358 \ub204\uacf5 \ud1b5\ub85c\uc758 \ud3d0\uc1c4\uac00 \uc774\ub8e8\uc5b4\uc9c0\ub294 \uacbd\uc6b0\uac00 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc774 \uc791\uc6a9 \uae30\uc804\uc774 \ubc14\ub85c \uc720\ub7fd\uc5d0\uc11c \uc815\uc2dd \ud5c8\uac00\ubc1b\uc740 darvadstrocel(Cx601, \uc0c1\ud488\uba85 Alofisel)\uc758 \uadfc\uac70\uac00 \ub41c \uba54\ucee4\ub2c8\uc998\uc785\ub2c8\ub2e4. \ubcf5\uc7a1 \ud56d\ubb38\uc8fc\uc704\ub204\uacf5\uc5d0 \ub300\ud55c \uc801\uc751\uc99d\uc73c\ub85c, 2018\ub144\uc5d0 \uc720\ub7fd \uc758\uc57d\ud488\uccad(EMA)\uc758 \ud5c8\uac00\ub97c \ubc1b\uc558\uc2b5\ub2c8\ub2e4. \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uac00 \ud2b9\uc815 \uc801\uc751\uc99d\uc5d0\uc11c \uaddc\uc81c \ub2f9\uad6d\uc758 \uc815\uc2dd \ud5c8\uac00\uc5d0 \uc774\ub978 \ub4dc\ubb38 \uc0ac\ub840 \uc911 \ud558\ub098\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ud55c\uad6d\uc5d0\uc11c 2012\ub144\ubd80\ud130 \uc0ac\uc6a9\ub418\uc5b4 \uc628 \ud050\ud53c\uc2a4\ud15c(Cupistem)\ub3c4 \uc720\uc0ac\ud55c \uc791\uc6a9 \uae30\uc804\uc5d0 \uadfc\uac70\ud55c \uc790\uac00 \uc9c0\ubc29\uc720\ub798 MSC \uc81c\ud488\uc73c\ub85c, \ud06c\ub860\ubcd1 \ud56d\ubb38\uc8fc\uc704\ub204\uacf5\uc5d0 \ub300\ud55c \uc2dd\uc57d\ucc98 \ud5c8\uac00\ub97c \ubc1b\uc558\uc2b5\ub2c8\ub2e4. \uc989, \uc904\uae30\uc138\ud3ec\uac00 \ud06c\ub860\ubcd1 \ub204\uacf5\uc5d0 \uc791\uc6a9\ud55c\ub2e4\ub294 \uac1c\ub150 \uc790\uccb4\ub294 \uc774\ubbf8 \ud55c\uad6d\uc5d0\uc11c\ub3c4 \uc784\uc0c1 \ud604\uc7a5\uc5d0\uc11c \ud655\ub9bd\ub41c \uc0ac\uc2e4\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \uc138 \uac00\uc9c0 \uc791\uc6a9\uc774 \ud06c\ub860\ubcd1\uc5d0 \ub3d9\uc2dc\uc5d0 \uc791\uc6a9<\/h3>\n\n\n\n

                    \uc774 \uc791\uc6a9\ub4e4\uc744 \uc815\ub9ac\ud558\uba74, MSC\ub294 \ud06c\ub860\ubcd1\uc5d0 \ub300\ud574 \uc138 \uac00\uc9c0 \uacbd\ub85c\ub85c \uc791\uc6a9\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uccab\uc9f8\ub294 \uba74\uc5ed \uc870\uc808. \uba74\uc5ed\uacc4\ub97c \uad11\ubc94\uc704\ud558\uac8c \uc5b5\uc81c\ud558\uc9c0 \uc54a\uace0, \uade0\ud615\uc744 \ud68c\ubcf5\uc2dc\ud0a4\ub294 \ubc29\ud5a5\uc73c\ub85c \uc791\uc6a9\ud569\ub2c8\ub2e4. \ub458\uc9f8\ub294 \uad6d\uc18c \uc870\uc9c1 \uce58\uc720. \ub204\uacf5\uc758 \ud3d0\uc1c4\uc640 \uc190\uc0c1\ub41c \uc7a5\uc810\ub9c9\uc758 \uce58\uc720\ub97c \ub3d5\uc2b5\ub2c8\ub2e4. \uc14b\uc9f8\ub294 \uc12c\uc720\ud654 \uc5b5\uc81c. \ud611\ucc29\uc758 \uc6d0\uc778\uc774 \ub418\ub294 \ud749\ud130 \ud615\uc131\uc744 \ub2a6\ucd9c \uac00\ub2a5\uc131\uc774 \ubcf4\uace0\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc5b4\ub290 \uac83\ub3c4 \uc989\ud6a8\uc131\uc740 \uc5c6\uc2b5\ub2c8\ub2e4. \uc2a4\ud14c\ub85c\uc774\ub4dc\ucc98\ub7fc \uba70\uce60 \ub9cc\uc5d0 \ud6a8\uacfc\uac00 \ub098\ud0c0\ub098\ub294 \uc57d\uc774 \uc544\ub2c8\ub77c, \uc0dd\ubb3c\ud559\uc801 \uacfc\uc815\uc774 \uc791\ub3d9\ud558\uae30\uae4c\uc9c0 \uba87 \uc8fc\uc5d0\uc11c \uba87 \ub2ec\uc774 \uac78\ub9bd\ub2c8\ub2e4. \uce58\ub8cc\ub97c \uac80\ud1a0\ud558\uc2e4 \ub54c \uc815\ud655\ud788 \uc774\ud574\ud574 \ub450\uc2e4 \ud544\uc694\uac00 \uc788\ub294 \ubd80\ubd84\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \ud06c\ub860\ubcd1 \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc758 \uc784\uc0c1\uc2dc\ud5d8 \uadfc\uac70<\/mark><\/h2>\n\n\n
                    \n
                    \"\ud06c\ub860\ubcd1
                    ADMIRE-CD \uc784\uc0c1\uc2dc\ud5d8(Pan\u00e9s et al., Lancet 2016): 24\uc8fc \ubc0f 52\uc8fc \uc2dc\uc810\uc5d0\uc11c\uc758 \ubcf5\ud569 \uad00\ud574\uc728. \ub3d9\uc885 \uc9c0\ubc29\uc720\ub798 MSC\uad70\uacfc \uc704\uc57d\uad70\uc758 \ube44\uad50.<\/figcaption><\/figure>\n<\/div>\n\n\n

                    \ub204\uacf5\uc5d0 \ub300\ud55c ADMIRE-CD \uc784\uc0c1\uc2dc\ud5d8 \uacb0\uacfc<\/h3>\n\n\n\n

                    \ud06c\ub860\ubcd1 \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc5d0\uc11c \uac00\uc7a5 \uac15\ub825\ud55c \uadfc\uac70\ub294 \ub204\uacf5\uc5d0 \ub300\ud55c \uc5f0\uad6c\uc5d0\uc11c \ub098\uc654\uc2b5\ub2c8\ub2e4. Pan\u00e9s \ub4f1\uc774 2016\ub144 \uc758\ud559 \uc800\ub110 Lancet\uc5d0 \ubc1c\ud45c\ud55c ADMIRE-CD \uc784\uc0c1\uc2dc\ud5d8\uc740 \uc81c3\uc0c1 \ubb34\uc791\uc704 \uc774\uc911\ub9f9\uac80 \uc704\uc57d \ub300\uc870 \uc2dc\ud5d8\uc73c\ub85c, \uc784\uc0c1 \uc5f0\uad6c \uc911 \uac00\uc7a5 \uc2e0\ub8b0\ub3c4 \ub192\uc740 \uc124\uacc4\ub85c \uc9c4\ud589\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ub300\uc0c1\uc740 \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\ub97c \ud3ec\ud568\ud55c \uae30\uc874 \uce58\ub8cc\uc5d0 \uc800\ud56d\uc131\uc744 \ubcf4\uc778 \ubcf5\uc7a1 \ud56d\ubb38\uc8fc\uc704\ub204\uacf5 \ud658\uc790 212\uba85. \ub3d9\uc885 \uc9c0\ubc29\uc720\ub798 MSC(darvadstrocel) \ub2e8\ud68c \uad6d\uc18c \uc8fc\uc785\uad70\uacfc \uc704\uc57d\uad70\uc5d0 \ubb34\uc791\uc704 \ubc30\uc815\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    24\uc8fc \uc2dc\uc810\uc758 \ubcf5\ud569 \uad00\ud574\uc728(\uce58\ub8cc\ud55c \uc678\ubd80 \uac1c\uad6c\ubd80\uc758 \uc644\uc804\ud55c \ud3d0\uc1c4, \uadf8\ub9ac\uace0 MRI\uc5d0\uc11c 2cm \ucd08\uacfc \ub18d\uc591\uc758 \ubd80\uc7ac\ub85c \uc815\uc758)\uc740 MSC\uad70 50%, \uc704\uc57d\uad70 34%\ub85c \ud1b5\uacc4\uc801\uc73c\ub85c \uc720\uc758\ud55c \ucc28\uc774\ub97c \ubcf4\uc600\uc2b5\ub2c8\ub2e4. \uac19\uc740 \uc2dc\ud5d8\uc758 52\uc8fc \uc2dc\uc810 \uacb0\uacfc(Pan\u00e9s et al., Gastroenterology 2018)\uc5d0\uc11c\ub3c4 MSC\uad70 56.3% \ub300 \uc704\uc57d\uad70 38.6%\ub85c, 1\ub144 \uc2dc\uc810\uae4c\uc9c0 \ud6a8\uacfc\uac00 \uc9c0\uc18d\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc548\uc804\uc131\ub3c4 \uc591\ud638\ud558\uc5ec, \uac00\uc7a5 \ud754\ud55c \uc774\uc0c1 \ubc18\uc751\uc740 \uc8fc\uc0ac \ubd80\uc704\uc758 \uacbd\ubbf8\ud55c \ud1b5\uc99d\uc774\uc5c8\uc73c\uba70 \ubaa8\ub450 \ucc98\uce58 \uc5c6\uc774 \ud638\uc804\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc774 \uacb0\uacfc\ub97c \ubc14\ud0d5\uc73c\ub85c \uc720\ub7fd \uc758\uc57d\ud488\uccad\uc740 2018\ub144\uc5d0 darvadstrocel\uc744 \ube44\ud65c\ub3d9\uc131 \ub610\ub294 \uacbd\ub3c4 \ud65c\ub3d9\uc131 \uc7a5\uad00 \ubcd1\ubcc0\uc744 \uac00\uc9c4 \uc131\uc778 \ud06c\ub860\ubcd1 \ud658\uc790\uc758 \ubcf5\uc7a1\ub204\uacf5 \uce58\ub8cc\uc81c\ub85c \uc815\uc2dd \ud5c8\uac00\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \ub8e8\uba58 \ud06c\ub860\ubcd1\uc5d0 \ub300\ud55c \uc815\ub9e5 \ud22c\uc5ec \uc784\uc0c1 \ub370\uc774\ud130<\/h3>\n\n\n\n

                    \uc7a5\uad00 \uc790\uccb4\uc758 \uc5fc\uc99d(\ub8e8\uba58 \ud06c\ub860\ubcd1)\uc5d0 \ub300\ud55c \uc815\ub9e5 MSC \ud22c\uc5ec\uc758 \uadfc\uac70\ub294 \ub204\uacf5\ub9cc\ud07c \uc131\uc219\ud558\uc9c0\ub294 \uc54a\uc558\uc9c0\ub9cc, \uba87 \uac00\uc9c0 \uc911\uc694\ud55c \uc2dc\ud5d8\uc774 \ubc1c\ud45c\ub418\uc5b4 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    Forbes \ub4f1\uc774 2014\ub144 Clinical Gastroenterology and Hepatology\uc5d0 \ubcf4\uace0\ud55c \uc81c2\uc0c1 \uc2dc\ud5d8\uc5d0\uc11c\ub294, \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\ub97c \ud3ec\ud568\ud55c \uae30\uc874 \uce58\ub8cc\uc5d0 \uc800\ud56d\uc131\uc744 \ubcf4\uc778 \ub8e8\uba58 \ud06c\ub860\ubcd1 \ud658\uc790 15\uba85\uc5d0\uac8c \ub3d9\uc885 \uace8\uc218\uc720\ub798 MSC\ub97c \uc8fc 1\ud68c\uc529 \ucd1d 4\ud68c \uc815\ub9e5 \ud22c\uc5ec\ud588\uc2b5\ub2c8\ub2e4. 15\uba85 \uc911 12\uba85\uc5d0\uc11c CDAI(\ud06c\ub860\ubcd1 \ud65c\ub3d9\uc131 \uc9c0\uc218)\uac00 100\uc810 \uc774\uc0c1 \uac10\uc18c\ud558\uc5ec \uc784\uc0c1\uc801 \ubc18\uc751\uc744 \uc5bb\uc5c8\uc2b5\ub2c8\ub2e4. 3\uba85\uc740 \uc784\uc0c1\uc801 \uad00\ud574\uc5d0 \ub3c4\ub2ec\ud588\uc2b5\ub2c8\ub2e4. \uc911\ub300\ud55c \uc138\ud3ec \uad00\ub828 \uc774\uc0c1 \ubc18\uc751\uc740 \uad00\ucc30\ub418\uc9c0 \uc54a\uc558\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    Molendijk \ub4f1\uc774 2015\ub144 Gastroenterology\uc5d0 \ubcf4\uace0\ud55c \ub2e4\ub978 \uc2dc\ud5d8\uc5d0\uc11c\ub294, \ub09c\uce58\uc131 \ub204\uacf5\uc5d0 \ub300\ud55c \ub3d9\uc885 \uace8\uc218\uc720\ub798 MSC \uad6d\uc18c \uc8fc\uc785\uc5d0\uc11c \uc720\uc758\ud55c \ud3d0\uc1c4\uc728 \uac1c\uc120\uc774 \uc785\uc99d\ub418\uc5c8\uc2b5\ub2c8\ub2e4. Dhere \ub4f1\uc758 \uc81c1\uc0c1 \uc2dc\ud5d8(Aliment Pharmacol Ther 2016)\uc5d0\uc11c\ub3c4 \uc548\uc804\uc131 \ud504\ub85c\ud30c\uc77c\uc740 \uc591\ud638\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ub2e4\ub9cc \uc815\uc9c1\ud558\uac8c \ub9d0\uc500\ub4dc\ub9b4 \uc810\uc740, \ub8e8\uba58 \ud06c\ub860\ubcd1\uc5d0 \ub300\ud55c \uc815\ub9e5 \ud22c\uc5ec\uc5d0 \uc788\uc5b4\uc11c\ub294 ADMIRE-CD\uc5d0 \ud544\uc801\ud558\ub294 \uaddc\ubaa8\uc758 \uc81c3\uc0c1 \uc2dc\ud5d8\uc774 \uc544\uc9c1 \uc874\uc7ac\ud558\uc9c0 \uc54a\ub294\ub2e4\ub294 \uac83\uc785\ub2c8\ub2e4. \ub204\uacf5\uc5d0 \ub300\ud55c \uadfc\uac70\uc640 \ube44\uad50\ud558\uba74 \uadfc\uac70 \uc218\uc900\uc5d0 \ucc28\uc774\uac00 \uc788\uc2b5\ub2c8\ub2e4. \ud658\uc790\ubd84\uc774 \uc54c\uace0 \uacc4\uc154\uc57c \ud560 \uc0ac\uc2e4\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \uc790\uac00\uc138\ud3ec\uc640 \ub3d9\uc885 \uc81c\ub300\uc720\ub798 MSC\uc758 \ucc28\uc774<\/mark><\/h2>\n\n\n\n

                    \ud55c\uad6d\uc758 \ud050\ud53c\uc2a4\ud15c(\uc790\uac00)\uacfc \ub9d0\ub808\uc774\uc2dc\uc544\uc758 \ub3d9\uc885 \uc81c\ub300\uc720\ub798 \uc811\uadfc\ubc95<\/h3>\n\n\n\n

                    \uc904\uae30\uc138\ud3ec \uce58\ub8cc\ub294 \uc790\uae30 \ubab8\uc5d0\uc11c \ucc44\ucde8\ud55c \uc138\ud3ec\ub97c \uc0ac\uc6a9\ud558\ub294 “\uc790\uac00 \uc774\uc2dd”\uacfc \uac74\uac15\ud55c \uacf5\uc5ec\uc790\uc5d0\uac8c\uc11c \uc81c\uacf5\ubc1b\uc740 \uc138\ud3ec\ub97c \uc0ac\uc6a9\ud558\ub294 “\ub3d9\uc885 \uc774\uc2dd”\uc73c\ub85c \ud06c\uac8c \ub098\ub269\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ud55c\uad6d\uc5d0\uc11c 2012\ub144\uc5d0 \uc2dd\uc57d\ucc98 \ud5c8\uac00\ub97c \ubc1b\uc740 \ud050\ud53c\uc2a4\ud15c\uc740, \ud658\uc790 \ubcf8\uc778\uc758 \uc9c0\ubc29 \uc870\uc9c1\uc5d0\uc11c \ucc44\ucde8\ud55c \uc790\uac00 MSC\ub97c \ubc30\uc591\ud558\uc5ec \ub204\uacf5\uc5d0 \uc8fc\uc785\ud558\ub294 \uc790\uac00 \uc774\uc2dd \uc81c\ud488\uc785\ub2c8\ub2e4. \uba74\uc5ed\ud559\uc801 \uac70\ubd80\uc758 \uc704\ud5d8\uc774 \uc0ac\uc2e4\uc0c1 \uc5c6\ub2e4\ub294 \uc7a5\uc810\uc774 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ub2e4\ub9cc \ub9cc\uc131 \uc5fc\uc99d\uc131 \uc9c8\ud658\uc778 \ud06c\ub860\ubcd1\uc758 \ub9e5\ub77d\uc5d0\uc11c \uba87 \uac00\uc9c0 \uace0\ub824\ud560 \uc810\uc774 \uc788\uc2b5\ub2c8\ub2e4. \ucc44\ucde8\uc5d0 \ub530\ub974\ub294 \uce68\uc2b5(\uc9c0\ubc29\ud761\uc785), \ubc30\uc591 \uae30\uac04 \ub3d9\uc548\uc758 \ub300\uae30, \uadf8\ub9ac\uace0 \uac00\uc7a5 \uc911\uc694\ud55c \uc810\uc73c\ub85c \uc624\ub7ab\ub3d9\uc548 \ud06c\ub860\ubcd1\uc744 \uc553\uc544 \uc624\uc2e0 \ud658\uc790\ubd84 \ubcf8\uc778\uc758 \uc138\ud3ec \ud488\uc9c8 \ubb38\uc81c\uac00 \uc788\uc2b5\ub2c8\ub2e4. \uc5ec\ub7ec \uc5f0\uad6c\uc5d0\uc11c \ub9cc\uc131 \uc790\uac00\uba74\uc5ed \uc9c8\ud658 \ud658\uc790\uc5d0\uac8c\uc11c \ucc44\ucde8\ud55c MSC\uac00 \uac74\uac15\ud55c \uacf5\uc5ec\uc790\uc758 MSC\uc5d0 \ube44\ud574 \uc99d\uc2dd \ub2a5\ub825\uacfc \uba74\uc5ed \uc870\uc808 \ub2a5\ub825\uc774 \uac10\uc18c\ub418\uc5b4 \uc788\uc74c\uc774 \ud655\uc778\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    “\uce58\ub8cc\uc758 \ud575\uc2ec\uc778 \uba74\uc5ed \uc870\uc808 \uc791\uc6a9\uc774 \ucc98\uc74c\ubd80\ud130 \uc57d\ud574\uc9c4 \uc138\ud3ec\ub97c \uc0ac\uc6a9\ud55c\ub2e4”\ub294 \uc810\uc740, \ud2b9\ud788 \ud06c\ub860\ubcd1 \uac19\uc740 \uba74\uc5ed \uc9c8\ud658\uc5d0\uc11c \uace0\ub824\ud574\uc57c \ud560 \ubd80\ubd84\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \ub9d0\ub808\uc774\uc2dc\uc544\uc5d0\uc11c \uc0ac\uc6a9\ud558\ub294 \ub3d9\uc885 \uc81c\ub300\uc720\ub798 MSC<\/h3>\n\n\n\n

                    \uc800\ud76c\uac00 \ub9d0\ub808\uc774\uc2dc\uc544\uc5d0\uc11c \uc9c4\ud589\ud558\ub294 \ud06c\ub860\ubcd1 \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc5d0\uc11c\ub294, \uac74\uac15\ud55c \uc2e0\uc0dd\uc544\uc758 \uc81c\ub300 \uc870\uc9c1(\uc6cc\ud2bc \uc824\ub9ac)\uc5d0\uc11c \ucc44\ucde8\ud55c \ub3d9\uc885 MSC\ub97c \uc0ac\uc6a9\ud569\ub2c8\ub2e4. \ub3d9\uc758\ub97c \ubc1b\uc740 \ub9cc\uc0ad \ubd84\ub9cc \uc2dc\uc810\uc5d0 \uc218\uc9d1\ub418\uba70, \ud488\uc9c8 \uad00\ub9ac\ub41c \ubc30\uce58\ub85c \uc81c\uc870\ub418\ub294 \uc138\ud3ec\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc81c\ub300\uc720\ub798 MSC\ub294 \uc0dd\ubb3c\ud559\uc801\uc73c\ub85c \uc80a\uace0, \uba74\uc5ed \uc870\uc808 \ub2a5\ub825\uc774 \ud2b9\ud788 \uac15\ud55c \uac83\uc73c\ub85c \uc54c\ub824\uc838 \uc788\uc2b5\ub2c8\ub2e4. \ub610\ud55c \uba74\uc5ed\ud559\uc801 \uac70\ubd80\ub97c \uc720\ubc1c\ud558\ub294 \uc138\ud3ec \ud45c\uba74 \ub9c8\ucee4\uc758 \ubc1c\ud604\uc774 \ub0ae\uae30 \ub54c\ubb38\uc5d0, \ud0c0\uc778\uc758 \uc138\ud3ec\ub77c\ub3c4 \uac70\ubd80 \ubc18\uc751\uc740 \ub9e4\uc6b0 \ub4dc\ubb45\ub2c8\ub2e4. \uc2e4\uc81c\ub85c ADMIRE-CD\ub97c \ud3ec\ud568\ud55c \ub3d9\uc885 MSC \uc784\uc0c1\uc2dc\ud5d8\uc5d0\uc11c \uba74\uc5ed \uac70\ubd80\uac00 \uc784\uc0c1\uc801\uc73c\ub85c \ubb38\uc81c\uac00 \ub41c \ubcf4\uace0\ub294 \uac70\uc758 \uc5c6\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc624\ub79c \uae30\uac04 \uba74\uc5ed\uc758 \ub9cc\uc131\uc801 \uc774\uc0c1\uc744 \uc548\uace0 \uc0b4\uc544\uc624\uc2e0 \ud06c\ub860\ubcd1 \ud658\uc790\ubd84\uaed8, \uac74\uac15\ud55c \uc5b4\ub9b0 \uc138\ud3ec\ub85c\ubd80\ud130 \uba74\uc5ed \uc870\uc808 \uc2e0\ud638\ub97c \ubc1b\uc744 \uc218 \uc788\ub2e4\ub294 \uc810\uc740 \uc790\uac00 \uc138\ud3ec\ub85c\ub294 \uc5bb\uae30 \uc5b4\ub824\uc6b4 \uc774\uc810\uc774 \ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \ud06c\ub860\ubcd1 \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uac00 \uc801\ud569\ud55c \ud658\uc790\uc640 \uadf8\ub807\uc9c0 \uc54a\uc740 \ud658\uc790<\/mark><\/h2>\n\n\n\n

                    \ud6a8\uacfc\uac00 \uae30\ub300\ub418\ub294 \ud658\uc790\ubd84\uc758 \ud504\ub85c\ud544<\/h3>\n\n\n\n

                    \uc784\uc0c1\uc2dc\ud5d8 \ub370\uc774\ud130\uc640 \uc800\ud76c\uc758 7\ub144 \uc774\uc0c1\uc758 \uc784\uc0c1 \uacbd\ud5d8\uc744 \ud1b5\ud574, \ud2b9\uc815 \ud658\uc790\uc0c1\uc5d0\uc11c \ubc18\uc751\uc774 \uc798 \ub098\ud0c0\ub098\ub294 \uacbd\ud5a5\uc774 \ud655\uc778\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uac00\uc7a5 \uadfc\uac70\uac00 \uac15\ud55c \uac83\uc740, \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\ub098 \uc218\uc220\ub85c \ucda9\ubd84\ud55c \uac1c\uc120\uc744 \uc5bb\uc9c0 \ubabb\ud55c \ubcf5\uc7a1 \ub204\uacf5\uc744 \uac00\uc9c4 \ubd84\uc785\ub2c8\ub2e4. ADMIRE-CD \uc784\uc0c1\uc2dc\ud5d8\uc758 \ub300\uc0c1\uc774 \ubc14\ub85c \uc774 \uc9d1\ub2e8\uc774\uba70, \uc81c3\uc0c1 \ubb34\uc791\uc704 \ub300\uc870 \uc2dc\ud5d8\uc5d0\uc11c \uc704\uc57d\uc744 \ub2a5\uac00\ud558\ub294 \ud6a8\uacfc\uac00 \uc785\uc99d\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ud55c\uad6d\uc5d0\uc11c \ud050\ud53c\uc2a4\ud15c\uc5d0 \ucda9\ubd84\ud788 \ubc18\uc751\ud558\uc9c0 \ubabb\ud558\uc2e0 \ubd84\ub3c4 \uc774 \ubc94\uc8fc\uc5d0 \ud3ec\ud568\ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ub8e8\uba58 \ud06c\ub860\ubcd1\uc5d0\uc11c \uc5ec\ub7ec \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\uc5d0 \ub09c\uce58\ud654\ub418\uace0, \ud65c\ub3d9\uc131 \uc5fc\uc99d\uc740 \uc788\uc9c0\ub9cc \uc544\uc9c1 \uc911\uc99d\uc758 \uad6c\uc870\uc801 \uc190\uc0c1(\uad11\ubc94\uc704\ud55c \ud611\ucc29\uc774\ub098 \ub204\uacf5 \ubcf5\ud569\ud654)\uc5d0\ub294 \uc774\ub974\uc9c0 \uc54a\uc740 \ubd84\ub3c4 \uac80\ud1a0 \ub300\uc0c1\uc774 \ub429\ub2c8\ub2e4. \ub2e4\ub9cc \uc774\ucabd\uc740 \ubc18\uc751\ub960\uc774 \ub300\ub7b5 40~60% \ubc94\uc704\ub85c, \ubcf4\uc7a5\uc774 \uc544\ub2cc \uac00\ub2a5\uc131\uc73c\ub85c \ubc1b\uc544\ub4e4\uc774\uc154\uc57c \ud560 \uc22b\uc790\uc784\uc744 \uc804\uc81c\ub85c \ub9d0\uc500\ub4dc\ub9bd\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc5b4\ub290 \ubd84\uc774\ub4e0 \ud604\uc7ac \uce58\ub8cc\uac00 \ucd5c\uc801\ud654\ub41c \uc0c1\ud0dc\uc774\uba70, \uc5ec\ud589\uc774 \uac00\ub2a5\ud55c \uc804\uc2e0 \uc0c1\ud0dc\uc5ec\uc57c \ud569\ub2c8\ub2e4. \uadf8\ub9ac\uace0 \ud6a8\uacfc\uac00 \ub098\ud0c0\ub098\uae30\uae4c\uc9c0 8~16\uc8fc\uac00 \uac78\ub9b0\ub2e4\ub294 \uc2dc\uac04 \ucd95\uc744 \ubc1b\uc544\ub4e4\uc774\uc2e4 \uc218 \uc788\uc5b4\uc57c \ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \uce58\ub8cc\ub97c \uad8c\ud558\uc9c0 \uc54a\ub294 \uacbd\uc6b0<\/h3>\n\n\n\n

                    \uae09\uc131\uc758 \uc911\uc99d \uc7ac\ubc1c\ub85c \uc785\uc6d0, \uc2a4\ud14c\ub85c\uc774\ub4dc \uc815\ub9e5 \ud22c\uc5ec, \uc751\uae09 \uc218\uc220 \uac80\ud1a0\uac00 \ud544\uc694\ud55c \uc0c1\ud0dc\uc5d0 \uacc4\uc2e0 \ubd84\uaed8\ub294 \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uac00 \uc801\uc808\ud55c \uc120\ud0dd\uc774 \uc544\ub2d9\ub2c8\ub2e4. \uc6b0\uc120\ub418\uc5b4\uc57c \ud560 \uac83\uc740 \uc548\uc815\ud654\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ubcf5\uac15 \ub0b4 \ub18d\uc591\uc774 \uc788\uc73c\uc2e0 \ubd84, \ud65c\ub3d9\uc131\uc758 \uc804\uc2e0 \uac10\uc5fc\uc774 \uc788\uc73c\uc2e0 \ubd84, \ubbf8\ucc98\uce58 \ud3d0\uc1c4\uc131 \ud611\ucc29\uc774 \uc788\uc73c\uc2e0 \ubd84\ub3c4 \uadf8 \ubb38\uc81c\ub4e4\uc758 \ud574\uacb0\uc774 \uba3c\uc800\uc785\ub2c8\ub2e4. MSC\ub294 \ub18d\uc591\uc744 \ubc30\ub18d\ud560 \uc218\ub3c4, \uc12c\uc720\ud654\ub41c \ud611\ucc29\uc744 \ubb3c\ub9ac\uc801\uc73c\ub85c \ub113\ud790 \uc218\ub3c4 \uc5c6\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ud65c\ub3d9\uc131 \uc545\uc131 \uc885\uc591\uc774 \uc788\uc73c\uc2e0 \ubd84, \ucd5c\uadfc \uc545\uc131 \uc885\uc591 \ubcd1\ub825\uc774 \uc788\uc73c\uc2e0 \ubd84\uc740 \uc804\ubb38\uc758\uc758 \ud3c9\uac00\uac00 \ud544\uc694\ud569\ub2c8\ub2e4. \uc784\uc2e0\u00b7\uc218\uc720 \uc911\uc774\uc2e0 \ubd84\uc740 \ub300\uc0c1\uc5d0\uc11c \uc81c\uc678\ub429\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uadf8\ub9ac\uace0 \ud604\uc7ac \uce58\ub8cc\ub85c \ubcd1\uc758 \ud65c\ub3d9\uc131\uc774 \ucda9\ubd84\ud788 \uc870\uc808\ub418\uace0, \ubd80\uc791\uc6a9\ub3c4 \uc218\uc6a9 \ubc94\uc704 \ub0b4\uc5d0 \uacc4\uc2e0 \ubd84\uaed8\ub294, \uc194\uc9c1\ud788 “\uc9c0\uae08 \uc2dc\uc810\uc5d0\uc11c \uc774 \uce58\ub8cc\uc758 \ucd94\uac00\uc801 \uc774\uc810\uc740 \uc81c\ud55c\uc801\uc77c \uc218 \uc788\uc2b5\ub2c8\ub2e4”\ub77c\uace0 \ub9d0\uc500\ub4dc\ub9bd\ub2c8\ub2e4. \ud574\uc678 \ub3c4\ud56d\uacfc \ube44\uc6a9 \ubd80\ub2f4\uc5d0 \uac78\ub9de\ub294 \ucd94\uac00 \ud6a8\uacfc\uac00 \uae30\ub300\ub418\uae30 \uc5b4\ub824\uc6b4 \uacbd\uc6b0, \uadf8 \ud310\ub2e8\uc744 \uacf5\uc720\ud558\ub294 \uac83\uc774 \uc800\ud76c\uc758 \ucc45\uc784\uc774\ub77c\uace0 \uc0dd\uac01\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

                    “\uc644\uce58\ub97c \ubcf4\uc7a5\ud558\ub294 \uce58\ub8cc”\ub97c \ucc3e\uc544 \uc624\uc2e0 \ubd84\uaed8\ub294, \uadf8\uac83\uc774 \ud604\uc7ac \uadfc\uac70\uac00 \ubcf4\uc5ec\uc8fc\ub294 \ubc14\uac00 \uc544\ub2d8\uc744 \uccab \uc628\ub77c\uc778 \uc0c1\ub2f4 \ub2e8\uacc4\uc5d0\uc11c \ubd84\uba85\ud788 \ub9d0\uc500\ub4dc\ub9bd\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \uce58\ub8cc \ud6c4 \uacbd\uacfc\uc640 \ud604\uc9c0\uc5d0\uc11c\uc758 \ud68c\ubcf5<\/h3>\n\n\n\n

                    \uce58\ub8cc \ud6c4 24~48\uc2dc\uac04 \uc774\ub0b4\uc5d0 \uacbd\ubbf8\ud55c \ubc1c\uc5f4\uc774\ub098 \uad8c\ud0dc\uac10\uc774 \ub098\ud0c0\ub098\ub294 \ubd84\uc774 \uc77c\uc815 \ube44\uc728\ub85c \uacc4\uc2ed\ub2c8\ub2e4. \uacf5\uc5ec \uc138\ud3ec\uc5d0 \ub300\ud55c \uba74\uc5ed\uacc4\uc758 \uc778\uc2dd \ubc18\uc751\uc73c\ub85c \uc5ec\uaca8\uc9c0\uba70, \ucc98\uce58 \uc5c6\uc774 \ud638\uc804\ub429\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ud06c\ub860\ubcd1\uc758 \ud604\uc7ac \uce58\ub8cc\ub294 \uce58\ub8cc \uc804\ud6c4\ub97c \ud1b5\ud574 \uacc4\uc18d \uc720\uc9c0\ud574 \uc8fc\uc2ed\uc2dc\uc624. \uc774 \uc810\uc740 \ub9e4\uc6b0 \uc911\uc694\ud569\ub2c8\ub2e4. \uc800\ud76c\uc758 \uce58\ub8cc\ub294 \ud604\uc7ac\uc758 \ud45c\uc900 \uce58\ub8cc\uc640 \ubcd1\ud589\ud558\uc5ec \uc9c4\ud589\ub418\ub294 \uac83\uc774\uba70, \ub300\uccb4\ud558\ub294 \uac83\uc774 \uc544\ub2d9\ub2c8\ub2e4. \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\ub098 \uba74\uc5ed\uc870\uc808\uc81c\uc758 \uc870\uc815\uc740 \ubc18\ub4dc\uc2dc \uc8fc\uce58\uc758\uc758 \ud310\ub2e8 \uc544\ub798 \uc774\ub8e8\uc5b4\uc838\uc57c \ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uacbd\uacfc \uad00\ucc30\uc740 3\uac1c\uc6d4, 6\uac1c\uc6d4, 12\uac1c\uc6d4 \uc2dc\uc810\uc5d0 \uc9c4\ud589\ud569\ub2c8\ub2e4. \ud658\uc790\ubd84\uaed8\ub294 \ubcc0 \ud69f\uc218, \ubcf5\ubd80 \uc99d\uc0c1, \uccb4\ub825, \uc2dd\uc695, \ud604\uc9c0\uc5d0\uc11c \uce21\uc815\ud55c \uc5fc\uc99d \uc9c0\ud45c\ub97c \uae30\ub85d\ud574 \uc8fc\uc2dc\uae30\ub97c \ubd80\ud0c1\ub4dc\ub9bd\ub2c8\ub2e4. \ub204\uacf5\uc774 \uc788\uc73c\uc2e0 \ubd84\uaed8\ub294 6\uac1c\uc6d4 \uc2dc\uc810\uc758 MRI \ud3c9\uac00\ub97c \uad8c\uc7a5\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uac1c\uc120\uc740 \ubcf4\ud1b5 8~16\uc8fc \uc0ac\uc774\uc5d0 \uc870\uae08\uc529 \ub098\ud0c0\ub098\uae30 \uc2dc\uc791\ud569\ub2c8\ub2e4. 6\uac1c\uc6d4 \uc2dc\uc810\uc5d0 \ubcc0\ud654\uac00 \uc804\ud600 \uc5c6\uc73c\uc2e0 \ubd84\uc774 1\ub144\uc5d0 \uac1c\uc120\ub418\ub294 \uacbd\uc6b0\ub294 \uacbd\ud5d8\uc0c1 \ub4dc\ubb45\ub2c8\ub2e4. \uc774\ud6c4\uc758 \uce58\ub8cc \uacc4\ud68d\uc744 \uc0dd\uac01\ud558\uc2dc\ub294 \ub370 \uc815\uc9c1\ud558\uac8c \ub9d0\uc500\ub4dc\ub9ac\uace0 \uc2f6\uc740 \uc815\ubcf4\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \ud658\uc790\ubd84\uc758 \uacbd\uacfc \uc0ac\ub840<\/mark><\/h2>\n\n\n\n

                    \uc5ec\ub7ec \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\ub85c \uc774\ucc28 \ubb34\ubc18\uc751\uc744 \uacbd\ud5d8\ud55c \ubd84\uc758 \uc0ac\ub840<\/h3>\n\n\n\n

                    40\ub300 \ud6c4\ubc18 \uc5ec\uc131, \uc720\ubcd1 \uae30\uac04 11\ub144. \uc774\uc804\uc5d0 \uc544\uc790\ud2f0\uc624\ud504\ub9b0, \uba54\ud1a0\ud2b8\ub809\uc138\uc774\ud2b8, \uc778\ud50c\ub9ad\uc2dc\ub9d9, \uc544\ub2ec\ub9ac\ubb34\ub9d9\uc744 \uac70\uce58\uace0, \uac00\uc7a5 \ucd5c\uadfc\uc5d0\ub294 \ubca0\ub3cc\ub9ac\uc8fc\ub9d9\uc744 \uc0ac\uc6a9 \uc911\uc774\uc168\uc2b5\ub2c8\ub2e4. \ucc98\uc74c \uc138 \uc57d\uc81c\ub294 \uac01\uac01 2~3\ub144 \uc815\ub3c4 \ud6a8\uacfc\ub97c \ubcf4\uc600\uc73c\ub098 \uc810\ucc28 \uc57d\ud574\uc9c0\uac70\ub098 \uc77c\uc0c1\uacfc \uc591\ub9bd\ud558\uae30 \uc5b4\ub824\uc6b4 \ubd80\uc791\uc6a9\uc774 \ub098\ud0c0\ub098 \ubcc0\uacbd\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \ubca0\ub3cc\ub9ac\uc8fc\ub9d9\uc73c\ub85c \uc7ac\ubc1c \ube48\ub3c4\ub294 \uc904\uc5c8\uc9c0\ub9cc \uc784\uc0c1\uc801 \uad00\ud574\uc5d0\ub294 \ub3c4\ub2ec\ud558\uc9c0 \uc54a\uc558\uace0, CRP\ub294 \uc548\uc815\uc801\uc778 \uc0c1\uc2b9 \uacbd\ud5a5, \ub300\ubcc0 \uce7c\ud504\ub85c\ud14d\ud2f4\ub3c4 \ub192\uc740 \uc218\uce58\ub97c \ubcf4\uc600\uc2b5\ub2c8\ub2e4. \ucd5c\uadfc \ub300\uc7a5\ub0b4\uc2dc\uacbd\uc5d0\uc11c \ud68c\uc7a5 \ub9d0\ub2e8\uacfc \uc0c1\ud589\uacb0\uc7a5\uc5d0 \ud65c\ub3d9\uc131 \ubcd1\ubcc0\uc774 \ud655\uc778\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc8fc\uce58\uc758\ub85c\ubd80\ud130 \uac00\uc7a5 \uc2ec\ud55c \ubd80\uc704\uc758 \uc218\uc220 \uac80\ud1a0\uac00 \ud604\uc2e4\uc801\uc778 \uc120\ud0dd\uc9c0\ub85c \uac70\ub860\ub418\uae30 \uc2dc\uc791\ud588\uc2b5\ub2c8\ub2e4. \ubcf8\uc778\uc740 \uac19\uc740 \ud06c\ub860\ubcd1\uc744 \uc553\ub294 \ud615\uc81c\uac00 15\ub144\uc5d0 \uac78\uccd0 \uc5ec\ub7ec \ucc28\ub840 \uc7a5 \uc808\uc81c\ub97c \uacbd\ud5d8\ud558\uace0 \uacb0\uad6d \ub2e8\uc7a5 \uc99d\ud6c4\uad70\uc73c\ub85c \uace0\ud1b5\ubc1b\ub294 \ubaa8\uc2b5\uc744 \uc9c0\ucf1c\ubd10 \uc624\uc168\uae30 \ub54c\ubb38\uc5d0, \uc218\uc220\uc740 \uac00\ub2a5\ud55c \ud55c \ud53c\ud558\uace0 \uc2f6\ub2e4\ub294 \ub9c8\uc74c\uc774 \uac15\ud558\uc168\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    2025\ub144 \ucd08, \ubcf8\uc778\uc774 \uc9c1\uc811 \uacf5\uac1c\ub41c \uc784\uc0c1 \uadfc\uac70\ub97c \ud655\uc778\ud558\uc2e0 \ud6c4 \uc800\ud76c\uc5d0\uac8c \uc0c1\ub2f4\uc744 \uc694\uccad\ud558\uc168\uc2b5\ub2c8\ub2e4. \uc9c4\ub8cc \uae30\ub85d\uc744 \uc138\uc2ec\ud788 \uac80\ud1a0\ud55c \uacb0\uacfc, \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c \ub09c\uce58\ud654, \uad6c\uc870 \ubcc0\ud654\ubcf4\ub2e4 \uc5fc\uc99d\uc774 \uc8fc\uccb4, \uc751\uae09 \uc218\uc220\uc774 \ud544\uc694\ud55c \ubcd1\ubcc0 \uc5c6\uc74c, \ud604\uc7ac \uce58\ub8cc\uc640 \ubcd1\uc6a9\ud55c\ub2e4\ub294 \uc774\ud574 \uc704\uc5d0\uc11c \uce58\ub8cc \ub300\uc0c1\uc774 \ub420 \uc218 \uc788\ub2e4\uace0 \ud310\ub2e8\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    6\uac1c\uc6d4\uc5d0 \uac78\uccd0 \ubcc0\ud654\uac00 \ub098\ud0c0\ub09c \uacbd\uacfc<\/h3>\n\n\n\n

                    \ub3d9\uc885 \uc81c\ub300\uc720\ub798 MSC\uc758 \uc815\ub9e5 \ud22c\uc5ec\ub97c 1\ud68c \ub0b4\uc6d0\uc73c\ub85c \uc9c4\ud589\ud588\uc2b5\ub2c8\ub2e4. \uc815\ub9e5 \ud22c\uc5ec \uc790\uccb4\ub294 \ubb38\uc81c\uc5c6\uc774 \ub05d\ub0ac\uace0, \uadf8 \ud6c4 36\uc2dc\uac04 \uc815\ub3c4 \ubbf8\uc5f4\uc774 \uc788\uc5c8\uc73c\uba70 \uba70\uce60\uc740 \uc804\uc2e0\uc5d0 \uad8c\ud0dc\uac10\uc774 \ub0a8\uc558\ub2e4\uace0 \ud558\uc168\uc2b5\ub2c8\ub2e4. \uc0ac\uc804\uc5d0 \uc548\ub0b4\ub4dc\ub9b0 \ubc94\uc704 \ub0b4\uc758 \ubc18\uc751\uc774\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uccab 8\uc8fc\ub294 \ub69c\ub837\ud55c \ubcc0\ud654\uac00 \uc5c6\uc5c8\uace0, \ubcf8\uc778\uc740 \ubd88\uc548\uac10\uc744 \ub290\ub07c\ub358 \uc2dc\uae30\uc600\ub2e4\uace0 \ud558\uc168\uc2b5\ub2c8\ub2e4. \uadf8\ub7ec\ub098 10\uc8fc \ubb34\ub835\ubd80\ud130 \uc544\uce68\uc758 \ubcc0\uc758 \uc808\ubc15\uac10\uc774 \uc774\uc804\ub9cc\ud07c \uc77c\uc815\ud558\uc9c0 \uc54a\ub2e4\ub294 \uac83\uc744 \ub290\ub07c\uc168\uc2b5\ub2c8\ub2e4. 3\uac1c\uc6d4 \uc2dc\uc810\uc5d0 \ubcc0 \ud69f\uc218\uac00 \ud558\ub8e8 6~7\ud68c\uc5d0\uc11c 3~4\ud68c\ub85c \uc904\uc5c8\uace0, \uc624\ud6c4\uc758 \ud53c\ub85c\uac10\ub3c4 \uac1c\uc120\ub418\uc5c8\ub2e4\uace0 \ud558\uc168\uc2b5\ub2c8\ub2e4. 6\uac1c\uc6d4 \uc2dc\uc810\uc5d0 CRP\ub294 \uce58\ub8cc \uc804\ubcf4\ub2e4 \uc57d 60% \uac10\uc18c\ud588\uace0, \ud604\uc9c0 \uc8fc\uce58\uc758\ub85c\ubd80\ud130 \uce7c\ud504\ub85c\ud14d\ud2f4\ub3c4 \ud06c\uac8c \ub5a8\uc5b4\uc84c\ub2e4\ub294 \ubcf4\uace0\uac00 \uc788\uc5c8\uc2b5\ub2c8\ub2e4. \ubca0\ub3cc\ub9ac\uc8fc\ub9d9\uc740 \uacc4\uc18d \uc720\uc9c0\ud558\uc168\uace0, 12\uac1c\uc6d4 \uc2dc\uc810\uc758 \ud3c9\uac00\uae4c\uc9c0 \ud604\uc7ac\uc758 \uc6a9\ub7c9\uc744 \uc720\uc9c0\ud558\ub294 \ubc29\ud5a5\uc73c\ub85c \uacb0\uc815\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uad00\ud574\uc5d0\ub294 \uc774\ub974\uc9c0 \ubabb\ud588\uc2b5\ub2c8\ub2e4. \ud06c\ub860\ubcd1\uc740 \uc5ec\uc804\ud788 \ub0a8\uc544 \uc788\uace0, \uc7a5\uae30 \uc9c0\uc18d\uc131\uc5d0 \ub300\ud574\uc11c\ub294 \uc55e\uc73c\ub85c\uc758 \uacbd\uacfc \uad00\ucc30\uc774 \ud544\uc694\ud569\ub2c8\ub2e4. \uadf8\ub7fc\uc5d0\ub3c4 “\uba87 \ub144 \ub3d9\uc548 \uacc4\uc18d \ub098\ube60\uc9c0\uae30\ub9cc \ud558\ub358 \ubcd1\uc774 \ub4dc\ub514\uc5b4 \ub2e4\ub978 \ubc29\ud5a5\uc73c\ub85c \uc6c0\uc9c1\uc774\uae30 \uc2dc\uc791\ud55c \uac10\uac01\uc774 \uc788\ub2e4”\uace0 \ub9d0\uc500\ud558\uc168\uc2b5\ub2c8\ub2e4. \uc218\uc220\uc740 \uc801\uc5b4\ub3c4 \uc9c0\uae08\uc73c\ub85c\uc11c\ub294 \ubcf4\ub958\ub41c \uc0c1\ud0dc\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc774 \uacbd\uacfc\ub294 \uc2e4\uc81c \uc0ac\ub840\ub97c \uae30\ubc18\uc73c\ub85c \ud55c \uc775\uba85\ud654\ub41c \uae30\ub85d\uc774\uba70, \uac1c\uc778\ucc28\uac00 \uc788\uc2b5\ub2c8\ub2e4. \ubaa8\ub4e0 \ubd84\uc774 \uac19\uc740 \uacbd\uacfc\ub97c \ubcf4\uc774\ub294 \uac83\uc740 \uc544\ub2d9\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \ud06c\ub860\ubcd1 \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc758 \uc704\ud5d8\uacfc \uc815\uc9c1\ud55c \ud55c\uacc4<\/mark><\/h2>\n\n\n\n

                    \uc9c0\uae08\uae4c\uc9c0\uc758 \uc784\uc0c1\uc2dc\ud5d8\uc5d0\uc11c \ubcf4\uace0\ub41c \ubd80\uc791\uc6a9<\/h3>\n\n\n\n

                    \ub3d9\uc885 MSC \uce58\ub8cc\uc758 \uc548\uc804\uc131 \ud504\ub85c\ud30c\uc77c\uc740 ADMIRE-CD\ub97c \ud3ec\ud568\ud55c \uadf8\ub3d9\uc548\uc758 \uc784\uc0c1\uc2dc\ud5d8\uc5d0\uc11c \uc804\ubc18\uc801\uc73c\ub85c \uc591\ud638\ud588\uc2b5\ub2c8\ub2e4. \uc704\ud5d8\uc774 \uc5c6\ub2e4\uace0 \ub9d0\uc500\ub4dc\ub9ac\ub294 \uac83\uc774 \uc544\ub2c8\ub77c, \ucd95\uc801\ub41c \uc2dc\ud5d8 \ub370\uc774\ud130\uac00 \ubcf4\uc5ec\uc8fc\ub294 \uc0ac\uc2e4\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc815\ub9e5 \ud22c\uc5ec\uc5d0\uc11c \uac00\uc7a5 \ud754\ud55c \ubc18\uc751\uc740 \ud22c\uc5ec \ud6c4 24~48\uc2dc\uac04 \uc774\ub0b4\uc758 \uacbd\ubbf8\ud55c \ubc1c\uc5f4, \uad8c\ud0dc\uac10, \ub54c\ub54c\ub85c \ub450\ud1b5\uc774\uba70, \ubaa8\ub450 \ucc98\uce58 \uc5c6\uc774 \ud638\uc804\ub429\ub2c8\ub2e4. \ub204\uacf5\uc5d0 \ub300\ud55c \uad6d\uc18c \uc8fc\uc785\uc5d0\uc11c\ub294 \uc8fc\uc785 \ubd80\uc704\uc758 \uacbd\ubbf8\ud55c \ud1b5\uc99d\uc774 \uba70\uce60 \uc9c0\uc18d\ub418\ub294 \uac83\uc774 \ubcf4\uace0\ub418\uc5c8\uc2b5\ub2c8\ub2e4. ADMIRE-CD \uc2dc\ud5d8\uc5d0\uc11c 212\uba85\uc758 \ud658\uc790\ubd84 \uc911 \uc138\ud3ec \uc790\uccb4\uc5d0 \uae30\uc778\ud55c \uc911\ub300\ud55c \uc774\uc0c1 \ubc18\uc751\uc740 \ubcf4\uace0\ub418\uc9c0 \uc54a\uc558\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc774\ub860\uc801 \uc6b0\ub824\ub85c \uba74\uc5ed\uc870\uc808\uc81c\uc640\uc758 \ub3d9\uc2dc \ubcd1\uc6a9\uc5d0 \ub300\ud55c \ub17c\uc758\uac00 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub7f0 \uc774\uc720\ub85c \uc800\ud76c \ud074\ub9ac\ub2c9\uc5d0\uc11c\ub294 \ud06c\ub860\ubcd1\uc758 \ud604\uc7ac \uce58\ub8cc\ub97c \uc911\ub2e8\ud558\uc2dc\ub3c4\ub85d \uad8c\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\ub098 \uba74\uc5ed\uc870\uc808\uc81c\uc758 \uc870\uc815\uc740 \ubc18\ub4dc\uc2dc \uc8fc\uce58\uc758\uc758 \ud310\ub2e8\uc744 \ub530\ub77c \uc8fc\uc2ed\uc2dc\uc624. \ub610\ud55c 2~3\ub144\uc744 \ub118\ub294 \uc7a5\uae30 \uc548\uc804\uc131 \ub370\uc774\ud130\ub294 \ud604\uc2dc\uc810\uc5d0\uc11c \uc81c\ud55c\uc801\uc785\ub2c8\ub2e4. \uc815\uc9c1\ud558\uac8c \ub9d0\uc500\ub4dc\ub824\uc57c \ud560 \ud55c\uacc4\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uac00 \ud560 \uc218 \uc5c6\ub294 \uc77c<\/h3>\n\n\n\n

                    \uacfc\ub3c4\ud55c \uae30\ub300\ub97c \ud53c\ud558\uae30 \uc704\ud574 \ubd84\uba85\ud788 \ub9d0\uc500\ub4dc\ub9b4 \ubd80\ubd84\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc904\uae30\uc138\ud3ec \uce58\ub8cc\ub294 \uc12c\uc720\ud654\ub41c \ud611\ucc29\uc744 \ubb3c\ub9ac\uc801\uc73c\ub85c \ub113\ud790 \uc218 \uc5c6\uc2b5\ub2c8\ub2e4. \uc774\ubbf8 \ud749\ud130\ub85c \uad73\uc5b4 \ub0b4\uac15\uc774 \ud604\uc800\ud788 \uc881\uc544\uc9c4 \uc7a5\uad00\uc740 MSC\ub85c \uc7ac\uac1c\ud1b5\ub418\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \uc7a5\ud3d0\uc0c9 \uc99d\uc0c1\uc744 \ubcf4\uc774\ub294 \ud611\ucc29\uc774 \uc788\ub294 \uacbd\uc6b0, \ub0b4\uc2dc\uacbd\uc801 \ud655\uc7a5\uc220\uc774\ub098 \uc678\uacfc \uce58\ub8cc\uac00 \uc801\uc808\ud55c \ub300\uc751\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ud65c\ub3d9\uc131 \ub18d\uc591\uc758 \ubc30\ub18d, \uc7a5\uae30\uc5d0 \ub3c4\ub2ec\ud55c \uae4a\uc740 \uad00\ud1b5\uc131 \ub204\uacf5\uc758 \ud3d0\uc1c4, \uc911\uc99d \ubcd1\ubcc0\uc5d0 \ub300\ud55c \uc678\uacfc \ucc98\uce58\uc758 \ub300\uccb4\uc5d0\ub294 \uc0ac\uc6a9\ud560 \uc218 \uc5c6\uc2b5\ub2c8\ub2e4. \ud45c\uc900 \uce58\ub8cc\uc758 \ub300\uccb4\uac00 \uc544\ub2c8\ub77c \ubcf4\uc644\uc801\uc778 \uc120\ud0dd\uc9c0\ub85c \uc790\ub9ac\ub9e4\uae40\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ubaa8\ub4e0 \ud658\uc790\ubd84\uaed8 \ud6a8\uacfc\uac00 \uc788\ub294 \uac83\uc740 \uc544\ub2d9\ub2c8\ub2e4. \ub09c\uce58\uc131 \ub204\uacf5\uc5d0 \ub300\ud55c ADMIRE-CD \uc2dc\ud5d8\uc5d0\uc11c \ubcf5\ud569 \uad00\ud574 \ub3c4\ub2ec\ub960\uc740 MSC\uad70\uc5d0\uc11c \uc57d 50%\uc600\uc2b5\ub2c8\ub2e4. \uc704\uc57d\uc744 \uc720\uc758\ud558\uac8c \uc0c1\ud68c\ud55c\ub2e4\uace0\ub294 \ud574\ub3c4, \uc808\ubc18\uc758 \ubd84\uc740 \ub300\uc870\uad70\uacfc \uac19\uc740 \uacb0\uacfc\uc600\uc2b5\ub2c8\ub2e4. \ub8e8\uba58 \ud06c\ub860\ubcd1\uc5d0 \ub300\ud55c \uc2dc\ud5d8\uc5d0\uc11c\ub294 \ubc18\uc751\ub960\uc774 40~60% \ubc94\uc704\uc600\uc2b5\ub2c8\ub2e4. \uc989 3~5\ud560\uc758 \ubd84\uc740 \uba85\ud655\ud55c \uac1c\uc120\uc744 \uacbd\ud5d8\ud558\uc9c0 \ubabb\ud55c\ub2e4\ub294 \ub73b\uc785\ub2c8\ub2e4. \uc0ac\uc804\uc5d0 \ud655\uc2e4\ud788 \uc608\uce21\ud560 \uc218 \uc5c6\ub294 \uc774 \uc22b\uc790\ub97c, \uce58\ub8cc\ub97c \uacb0\uc815\ud558\uc2dc\uae30 \uc804\uc5d0 \uc54c\ub824 \ub4dc\ub824\uc57c \ud55c\ub2e4\uace0 \uc0dd\uac01\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ud06c\ub860\ubcd1\uc5d0 \ub300\ud55c \uc904\uae30\uc138\ud3ec \uce58\ub8cc\ub294 \uadfc\uce58 \uc694\ubc95\uc774 \uc544\ub2d9\ub2c8\ub2e4. \uba74\uc5ed \uc774\uc0c1\uc744 \uc77c\uc73c\ud0a4\ub294 \uc720\uc804\uc801\u00b7\ud658\uacbd\uc801 \ubc30\uacbd\uc740 \uadf8\ub300\ub85c \ub0a8\uc2b5\ub2c8\ub2e4. \uc800\ud76c\uac00 \uc81c\uc2dc\ud560 \uc218 \uc788\ub294 \uc815\uc9c1\ud55c \uc790\ub9ac\ub9e4\uae40\uc740 “\ud65c\ub3d9\uc131 \uc5fc\uc99d\uc758 \uc870\uc808, \uac00\ub2a5\ud55c \ubc94\uc704\uc5d0\uc11c\uc758 \uc870\uc9c1 \uce58\uc720 \uc9c0\uc6d0, \ud1b5\uc81c\ub41c \uae30\uac04\uc758 \uc5f0\uc7a5\uc744 \uc2dc\ub3c4\ud558\ub294 \uc218\ub2e8. \ud604\uc7ac \uce58\ub8cc\uc640 \ubcd1\uc6a9\ud558\ub294 \uac83”\uc785\ub2c8\ub2e4. <\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \ud06c\ub860\ubcd1 \uc904\uae30\uc138\ud3ec \uce58\ub8cc \uc790\uc8fc \ubb3b\ub294 \uc9c8\ubb38<\/mark><\/h2>\n\n\n\n
                    \n
                    \n