{"id":25220,"date":"2026-05-19T14:53:09","date_gmt":"2026-05-19T06:53:09","guid":{"rendered":"https:\/\/stemcell-malaysia.com\/?page_id=25220"},"modified":"2026-05-19T14:53:10","modified_gmt":"2026-05-19T06:53:10","slug":"ulcerative-colitis","status":"publish","type":"page","link":"https:\/\/stemcell-malaysia.com\/ko\/conditions\/ulcerative-colitis\/","title":{"rendered":"\uada4\uc591\uc131 \ub300\uc7a5\uc5fc \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uff5c\uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c \uc774\ud6c4, \ub300\uc7a5\uc744 \ubcf4\uc874\ud560 \uc218 \uc788\ub294\uac00"},"content":{"rendered":"\n

\uada4\uc591\uc131 \ub300\uc7a5\uc5fc \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uff5c\uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c \uc774\ud6c4, \ub300\uc7a5\uc744 \ubcf4\uc874\ud560 \uc218 \uc788\ub294\uac00<\/h1>\n\n\n
\n
\"\uc774\ub978
\ud558\ub8e8\uc758 \uc2dc\uc791\uc744 \ud654\uc7a5\uc2e4\uae4c\uc9c0\uc758 \uac70\ub9ac\ub85c \uacc4\uc0b0\ud558\ub294 \uac83. \uadf8\uac83\uc774 \uada4\uc591\uc131 \ub300\uc7a5\uc5fc\uc744 \uc548\uace0 \uc0b4\uc544\uac00\ub294 \uc77c\uc0c1\uc758 \ud604\uc2e4\uc785\ub2c8\ub2e4.<\/figcaption><\/figure>\n<\/div>\n\n\n

\uc544\uce68\uc5d0 \ub208\uc744 \ub5b4\uc744 \ub54c \uac00\uc7a5 \uba3c\uc800 \ub5a0\uc62c\ub9ac\ub294 \uac83\uc774 “\uc9c0\uae08 \ud654\uc7a5\uc2e4\uc5d0 \ub2e4\ub140\uc640\uc57c \ud558\ub294\uac00”\ub77c\ub294 \uacc4\uc0b0\uc785\ub2c8\ub2e4. \ucd9c\uc7a5\uc740 \ube44\ud589\uae30 \uc548\uc5d0\uc11c\uc758 \ub450 \uc2dc\uac04\uc774 \ub450\ub824\uc6cc \ubbf8\ub8e8\uac8c \ub418\uace0, \ud68c\uc758 \uc911\uc5d0\ub294 \ud56d\uc0c1 \ube44\uc0c1\uad6c\uc640 \ud654\uc7a5\uc2e4 \uc704\uce58\ub97c \ud655\uc778\ud558\ub294 \uc2b5\uad00\uc774 \uc0dd\uacbc\uc2b5\ub2c8\ub2e4. \uac00\uc871\uacfc\uc758 \uc678\uc2dd, \uce5c\uad6c\uc640\uc758 \uc5ec\ud589\uc744 \uac70\uc808\ud558\ub294 \ud69f\uc218\uac00 \ub298\uc5b4\ub0ac\uace0, “\uc624\ub298 \ucee8\ub514\uc158\uc774 \uc5b4\ub5bb\uc2b5\ub2c8\uae4c”\ub77c\ub294 \uc9c8\ubb38\uc5d0 \uc815\uc9c1\ud558\uac8c \ub2f5\ud558\uae30\uac00 \uc810\uc810 \uc5b4\ub824\uc6cc\uc84c\uc2b5\ub2c8\ub2e4. \uada4\uc591\uc131 \ub300\uc7a5\uc5fc\uc744 \uc9c4\ub2e8\ubc1b\uace0 \uba87 \ub144\uc774 \uc9c0\ub0ac\ub2e4\uba74, \uc774\ub7f0 \uc77c\uc0c1\uc758 \uc791\uc740 \uacc4\uc0b0\ub4e4\uc774 \uc5bc\ub9c8\ub098 \uc0ac\ub78c\uc744 \uc9c0\uce58\uac8c \ud558\ub294\uc9c0 \uc798 \uc54c\uace0 \uacc4\uc2e4 \uac83\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

\ud55c\uad6d\uc5d0\ub294 2024\ub144 \uae30\uc900\uc73c\ub85c \uc57d 4\ub9cc \uba85\uc5d0\uc11c 5\ub9cc \uba85\uc5d0 \uc774\ub974\ub294 \uada4\uc591\uc131 \ub300\uc7a5\uc5fc \ud658\uc790\uac00 \uc788\ub294 \uac83\uc73c\ub85c \ucd94\uc815\ub429\ub2c8\ub2e4. 2010\ub144\uc5d0\ub294 \uc57d 1\ub9cc 6\ucc9c \uba85\uc774\uc5c8\uc73c\ub2c8, 10\ub144 \uc0ac\uc774\uc5d0 \uc57d 4.8\ubc30 \uac00\uae4c\uc774 \uc99d\uac00\ud55c \uc148\uc785\ub2c8\ub2e4. \uc2dd\uc2b5\uad00\uc758 \uc11c\uad6c\ud654, \uac00\uacf5\uc2dd\ud488\uc758 \ubcf4\ud3b8\ud654, \uadf8\ub9ac\uace0 \uc9c4\ub2e8 \uae30\uc220\uc758 \ud5a5\uc0c1\uc774 \ubcf5\ud569\uc801\uc73c\ub85c \uc791\uc6a9\ud558\uba74\uc11c \ud658\uc790 \uc218\ub294 \uacc4\uc18d \ub298\uace0 \uc788\uace0, 30\ub300(19.3%)\uc640 20\ub300(17.1%)\uc758 \ubc1c\ubcd1\uc774 \uac00\uc7a5 \ub9ce\uc2b5\ub2c8\ub2e4. \ud55c\ucc3d \uc77c\ud558\uace0 \uacf5\ubd80\ud558\uace0 \uac00\uc871\uc744 \uafb8\ub824\uac08 \uc2dc\uae30\uc5d0 \uc9c4\ub2e8\uc744 \ubc1b\ub294 \ubd84\ub4e4\uc774 \ub9ce\uc740 \uc9c8\ud658\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

\ub300\ubd80\ubd84\uc758 \ud658\uc790\ub294 5-ASA, \uc2a4\ud14c\ub85c\uc774\ub4dc, \uba74\uc5ed\uc5b5\uc81c\uc81c, \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\uc758 \ub2e8\uacc4\ub97c \uac70\uce58\uba70 \uad00\ud574\uc640 \uc7ac\ubc1c\uc744 \ubc18\ubcf5\ud569\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \ud658\uc790 10\uba85 \uc911 1~2\uba85\uc740 \uc77c\uc0dd \uc911 \uc5b4\ub290 \uc2dc\uc810\uc5d0 \ub300\uc7a5 \uc808\uc81c\uc220\uc744 \ubc1b\uac8c \ub41c\ub2e4\uace0 \uc54c\ub824\uc838 \uc788\uc2b5\ub2c8\ub2e4. \uadf8 \uacb0\uc815 \uc2dc\uc810\uc774 \uac00\uae4c\uc6cc\uc9c8 \ub54c, “\ub2e4\uc74c \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\ub97c \uc2dc\ub3c4\ud560 \uac83\uc778\uac00, \uc544\ub2c8\uba74 \uc218\uc220\uc744 \uac80\ud1a0\ud560 \uac83\uc778\uac00”\ub77c\ub294 \uc591\uc790\ud0dd\uc77c \uc55e\uc5d0\uc11c \uba48\ucdb0\uc11c\uac8c \ub429\ub2c8\ub2e4.<\/p>\n\n\n\n

\uc774 \uae00\uc740 \uadf8 \uc591\uc790\ud0dd\uc77c \uc0ac\uc774\uc5d0\uc11c \ub2e4\ub978 \uae38\uc744 \ucc3e\uc544\ubcf4\uace0 \uc2f6\uc740 \ubd84\ub4e4\uc744 \uc704\ud574 \uc37c\uc2b5\ub2c8\ub2e4. \uada4\uc591\uc131 \ub300\uc7a5\uc5fc\uc5d0 \ub300\ud55c \ub3d9\uc885 \uc81c\ub300 \uc720\ub798 \uac04\uc5fd \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uac00 \uc2e4\uc81c\ub85c \uc5b4\ub5a4 \uc784\uc0c1 \ub370\uc774\ud130\ub97c \uac00\uc9c0\uace0 \uc788\ub294\uc9c0, \uc5b4\ub5bb\uac8c \uc791\ub3d9\ud558\ub294\uc9c0, \ub204\uad6c\uc5d0\uac8c \ub9de\uace0 \ub204\uad6c\uc5d0\uac8c \ub9de\uc9c0 \uc54a\ub294\uc9c0\ub97c 7\ub144 \uc774\uc0c1 \ub9d0\ub808\uc774\uc2dc\uc544\uc5d0\uc11c 200\uba85 \uc774\uc0c1\uc744 \uce58\ub8cc\ud574 \uc628 \uacbd\ud5d8\uacfc \ud568\uaed8 \uac00\ub2a5\ud55c \ud55c \uc815\uc9c1\ud558\uac8c \uc815\ub9ac\ud588\uc2b5\ub2c8\ub2e4. \uc644\uce58\ub97c \uc57d\uc18d\ud558\ub294 \uae00\uc740 \uc544\ub2d9\ub2c8\ub2e4. \uc784\uc0c1\uc5d0\uc11c \ubcf8 \ud604\uc2e4\uc744 \uadf8\ub300\ub85c \uc804\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

<\/div>\n\n\n\n

\ubaa9\ucc28<\/mark><\/h2>\n\n\n
  1. \uada4\uc591\uc131 \ub300\uc7a5\uc5fc\uc740 \uc65c \uad00\ud574\ub41c \ub4a4\uc5d0\ub3c4 \ub2e4\uc2dc \ud0c0\uc624\ub974\ub294\uac00<\/a>
      <\/ol><\/li>
    1. \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c \uc774\ud6c4, \ud45c\uc900 \uce58\ub8cc\uac00 \ub05d\ub098\ub294 \uc790\ub9ac<\/a>
        <\/ol><\/li>
      1. \uac04\uc5fd \uc904\uae30\uc138\ud3ec\uac00 \uada4\uc591\uc131 \ub300\uc7a5\uc5fc\uc5d0 \uc791\uc6a9\ud558\ub294 \uc138 \uac00\uc9c0 \uba54\ucee4\ub2c8\uc998<\/a>
          <\/ol><\/li>
        1. \uada4\uc591\uc131 \ub300\uc7a5\uc5fc\uc5d0 \ub300\ud55c \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc758 \uc784\uc0c1 \uadfc\uac70<\/a>
            <\/ol><\/li>
          1. \ub3d9\uc885 \uc81c\ub300 \uc720\ub798 \uc904\uae30\uc138\ud3ec\ub97c \uc0ac\uc6a9\ud558\ub294 \uc774\uc720<\/a>
              <\/ol><\/li>
            1. \uada4\uc591\uc131 \ub300\uc7a5\uc5fc \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc5d0 \ub9de\ub294 \ubd84, \ub9de\uc9c0 \uc54a\ub294 \ubd84<\/a>
                <\/ol><\/li>
              1. \ud55c \ud658\uc790\uc758 \uce58\ub8cc \uacbd\ud5d8<\/a>
                  <\/ol><\/li>
                1. \uc704\ud5d8\uacfc \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uac00 \ud560 \uc218 \uc5c6\ub294 \uc77c<\/a>
                    <\/ol><\/li>
                  1. \uada4\uc591\uc131 \ub300\uc7a5\uc5fc \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc5d0 \uad00\ud55c \uc790\uc8fc \ubb3b\ub294 \uc9c8\ubb38<\/a><\/li>
                  2. \uc0c1\ub2f4\uc5d0 \ub300\ud558\uc5ec<\/a><\/li>
                  3. \ucc38\uace0\ubb38\ud5cc<\/a><\/li><\/ol><\/div>\n\n\n
                    <\/div>\n\n\n\n

                    \uada4\uc591\uc131 \ub300\uc7a5\uc5fc\uc740 \uc65c \uad00\ud574\ub41c \ub4a4\uc5d0\ub3c4 \ub2e4\uc2dc \ud0c0\uc624\ub974\ub294\uac00<\/mark><\/h2>\n\n\n\n

                    \uba74\uc5ed\uccb4\uacc4\uac00 \ub300\uc7a5\uc744 \uc801\uc73c\ub85c \uc624\uc778\ud558\ub294 \uc774\uc720<\/h3>\n\n\n\n

                    \uada4\uc591\uc131 \ub300\uc7a5\uc5fc\uc740 \uc790\uac00\uba74\uc5ed \uc9c8\ud658\uc785\ub2c8\ub2e4. \ubcf8\ub798 \uc138\uade0\uc774\ub098 \ubc14\uc774\ub7ec\uc2a4 \uac19\uc740 \uc678\ubd80 \uc704\ud611\uc73c\ub85c\ubd80\ud130 \ubab8\uc744 \uc9c0\ud0a4\ub294 \uba74\uc5ed\uccb4\uacc4\uac00, \uc5b4\ub5a4 \uc774\uc720\uc5d0\uc11c\uc778\uc9c0 \uc790\uae30 \uc790\uc2e0\uc758 \ub300\uc7a5 \uc810\ub9c9\uc744 \uacf5\uaca9 \ub300\uc0c1\uc73c\ub85c \uc778\uc2dd\ud574 \ubc84\ub9b0 \uc0c1\ud0dc\uac00 \ub9cc\uc131\uc801\uc73c\ub85c \uc774\uc5b4\uc9c0\ub294 \ubcd1\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uac74\uac15\ud55c \ub300\uc7a5\uc5d0\uc11c\ub294 \uc7a5\ub0b4\uc5d0 \uc0ac\ub294 \uc218\uc870 \uac1c\uc758 \uc138\uade0, \uc74c\uc2dd\uc758 \uc794\uc5ec\ubb3c, \ub300\uc0ac \ubd80\uc0b0\ubb3c \uc0ac\uc774\uc5d0\uc11c \uba74\uc5ed\uccb4\uacc4\uac00 \uc808\ubb18\ud55c \uade0\ud615\uc744 \uc720\uc9c0\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ubb34\uc5c7\uc744 \uacac\ub514\uace0 \ubb34\uc5c7\uc5d0 \ubc18\uc751\ud560\uc9c0\ub97c \ubbf8\uc138\ud558\uac8c \uc870\uc808\ud558\uba74\uc11c \ud3c9\ud654\ub97c \uc720\uc9c0\ud569\ub2c8\ub2e4. \uada4\uc591\uc131 \ub300\uc7a5\uc5fc\uc5d0\uc11c\ub294 \uc774 \uade0\ud615\uc774 \ubb34\ub108\uc9d1\ub2c8\ub2e4. \uacf5\uaca9 \uc5ed\ud560\uc758 \uba74\uc5ed\uc138\ud3ec\uac00 \ub300\uc7a5 \uc810\ub9c9\uc73c\ub85c \ubab0\ub824\ub4e4\uc5b4 \uc0ac\uc774\ud1a0\uce74\uc778(\uba74\uc5ed\uc138\ud3ec\ub07c\ub9ac \uc8fc\uace0\ubc1b\ub294 \ud654\ud559 \uba54\uc2e0\uc800 \ub2e8\ubc31\uc9c8\uc744 \ub9d0\ud569\ub2c8\ub2e4)\uc744 \ub300\ub7c9\uc73c\ub85c \ubc29\ucd9c\ud558\uae30 \uc2dc\uc791\ud569\ub2c8\ub2e4. \uc885\uc591\uad34\uc0ac\uc778\uc790 \uc54c\ud30c(TNF-\u03b1), \uc778\ud130\ub8e8\ud0a8-6, \uc778\ud130\ub8e8\ud0a8-1 \uac19\uc740 \ub300\ud45c\uc801\uc778 \uc5fc\uc99d\uc131 \uc0ac\uc774\ud1a0\uce74\uc778\uc774 \uc810\ub9c9\uc5d0 \uada4\uc591\uc744 \ub9cc\ub4e4\uace0, \ud608\ubcc0, \uc7a6\uc740 \ubcc0\uc758, \ubcf5\ud1b5\uc774\ub77c\ub294 \uc99d\uc0c1\uc73c\ub85c \uc774\uc5b4\uc9d1\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \uad00\ud574\uc640 \uc644\uce58\ub294 \ub2e4\ub978 \ub9d0\uc785\ub2c8\ub2e4<\/h3>\n\n\n\n

                    \ub9ce\uc740 \uada4\uc591\uc131 \ub300\uc7a5\uc5fc \ud658\uc790\ub294 \uce58\ub8cc\ub97c \ud1b5\ud574 \uad00\ud574 \uc0c1\ud0dc\uc5d0 \ub3c4\ub2ec\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uad00\ud574\ub780 \uc99d\uc0c1\uc774 \uac00\ub77c\uc549\uace0 \ub300\uc7a5\ub0b4\uc2dc\uacbd\uc73c\ub85c \uc810\ub9c9\uc758 \uc5fc\uc99d\uc774 \ud06c\uac8c \ud638\uc804\ub41c \uc0c1\ud0dc\ub97c \ub9d0\ud569\ub2c8\ub2e4. \uc784\uc0c1\uc801\uc73c\ub85c \ub9e4\uc6b0 \uc911\uc694\ud55c \ubaa9\ud45c\uc774\uace0, \ud658\uc790\uc5d0\uac8c\ub3c4 \ud070 \uc548\ub3c4\uac10\uc744 \uc8fc\ub294 \uc2dc\uae30\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ub2e4\ub9cc \uad00\ud574\ub294 \uc644\uce58\uac00 \uc544\ub2d9\ub2c8\ub2e4. \uba74\uc5ed\uccb4\uacc4\uac00 \ub300\uc7a5 \uc810\ub9c9\uc744 \uc798\ubabb \uc778\uc2dd\ud558\ub294 \uadfc\ubcf8 \uacbd\ud5a5\uc740 \uad00\ud574 \uc911\uc5d0\ub3c4 \uc0ac\ub77c\uc9c0\uc9c0 \uc54a\uace0, \uc57d\ubb3c\uc5d0 \uc758\ud574 \uc5b5\uc81c\ub418\uc5b4 \uc788\uac70\ub098 \uc6b0\uc5f0\ud788 \uc5fc\uc99d\uc758 \ud658\uacbd\uc774 \uc7a0\uc7a0\ud574\uc9c4 \uc0c1\ud0dc\uc5d0 \uac00\uae5d\uc2b5\ub2c8\ub2e4. \uac10\uae30\ub098 \uc704\uc7a5\uc5fc \uac19\uc740 \uac10\uc5fc, \uadf9\uc2ec\ud55c \uc2a4\ud2b8\ub808\uc2a4, \uc57d \ubcf5\uc6a9\uc744 \uc7a0\uc2dc \uac74\ub108\ub6f4 \uc0ac\uac74, \ub610\ub294 \ud2b9\ubcc4\ud55c \uc774\uc720 \uc5c6\uc774\ub3c4 \uc7ac\ubc1c\uc774 \uc77c\uc5b4\ub0a0 \uc218 \uc788\uc2b5\ub2c8\ub2e4. “\uad00\ud574\uc640 \uc7ac\ubc1c\uc744 \ubc18\ubcf5\ud558\ub294 \uc9c8\ud658”\uc774\ub77c\ub294 \uada4\uc591\uc131 \ub300\uc7a5\uc5fc\uc758 \ubcf8\uc9c8\uc774 \uc7a5\uae30 \uad00\ub9ac\ub97c \uc5b4\ub835\uac8c \ub9cc\ub4dc\ub294 \ud575\uc2ec\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c \uc774\ud6c4, \ud45c\uc900 \uce58\ub8cc\uac00 \ub05d\ub098\ub294 \uc790\ub9ac<\/mark><\/h2>\n\n\n\n

                    5-ASA\ubd80\ud130 \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\uae4c\uc9c0<\/h3>\n\n\n\n

                    \ud55c\uad6d\uc758 \uc9c4\ub8cc \uc9c0\uce68\uc5d0 \ub530\ub978 \uada4\uc591\uc131 \ub300\uc7a5\uc5fc \uce58\ub8cc\ub294 \ub2e8\uacc4\ubcc4 \uad6c\uc870\ub85c \uc9dc\uc5ec \uc788\uc2b5\ub2c8\ub2e4. \uacbd\uc99d\uc5d0\uc11c \uc911\ub4f1\uc99d\uc758 \uacbd\uc6b0, \uc6b0\uc120 5-\uc544\ubbf8\ub178\uc0b4\ub9ac\uc2e4\uc0b0, \ud754\ud788 5-ASA\ub77c\uace0 \ubd80\ub974\ub294 \uc57d\ubb3c\ub85c \uc2dc\uc791\ud569\ub2c8\ub2e4. \uba54\uc0b4\ub77c\uc9c4, \ud39c\ud0c0\uc0ac \ub4f1\uc774 \uc5ec\uae30\uc5d0 \uc18d\ud558\uba70, \ub300\uc7a5 \uc810\ub9c9\uc5d0 \uc9c1\uc811 \uc791\uc6a9\ud574 \uc5fc\uc99d\uc744 \uac00\ub77c\uc549\ud788\ub294 \uc57d\uc785\ub2c8\ub2e4. \ube44\uad50\uc801 \uacac\ub514\uae30 \uc26c\uc6cc \ub9ce\uc740 \ud658\uc790\uac00 \uc774 \ub2e8\uacc4\uc5d0\uc11c \uad00\ud574\ub97c \uc720\uc9c0\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    5-ASA\ub9cc\uc73c\ub85c \ucda9\ubd84\ud55c \ud6a8\uacfc\uac00 \uc5c6\uc744 \ub54c\ub294 \ud65c\ub3d9\uae30\uc758 \uc5fc\uc99d\uc744 \uac00\ub77c\uc549\ud788\uae30 \uc704\ud574 \ud504\ub808\ub4dc\ub2c8\uc194\ub860 \uac19\uc740 \uc2a4\ud14c\ub85c\uc774\ub4dc\uac00 \uc0ac\uc6a9\ub429\ub2c8\ub2e4. \ub2e8\uae30\uc801\uc73c\ub85c\ub294 \uac15\ub825\ud558\uc9c0\ub9cc, \uc7a5\uae30 \uc0ac\uc6a9\uc740 \uace8\ub2e4\uacf5\uc99d, \uccb4\uc911 \uc99d\uac00, \uac10\uc5fc \uc704\ud5d8 \uc0c1\uc2b9, \ud608\ub2f9 \uc0c1\uc2b9 \ub4f1 \ub204\uc801\ub418\ub294 \ubd80\uc791\uc6a9 \ub54c\ubb38\uc5d0 \ud65c\ub3d9\uae30 \ub2e8\uae30\uac04 \uc0ac\uc6a9\uc774 \uc6d0\uce59\uc785\ub2c8\ub2e4. \ub2e4\uc74c \ub2e8\uacc4\uc5d0\uc11c\ub294 \uc544\uc790\ud2f0\uc624\ud504\ub9b0 \ub4f1 \uba74\uc5ed\uc5b5\uc81c\uc81c\uac00 \ucd94\uac00\ub418\uc5b4 \uba74\uc5ed \uc804\uccb4\uc758 \ud1a4\uc744 \ub0ae\ucd94\uac8c \ub429\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uadf8\ub9ac\uace0 \ub354 \uac15\ud55c \ud65c\ub3d9\uc131\uc5d0\ub294 \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\uac00 \ub4f1\uc7a5\ud569\ub2c8\ub2e4. \uc778\ud50c\ub9ad\uc2dc\ub9d9(\ub808\ubbf8\ucf00\uc774\ub4dc), \uc544\ub2ec\ub9ac\ubb34\ub9d9(\ud734\ubbf8\ub77c) \uac19\uc740 \ud56dTNF-\u03b1 \ud56d\uccb4, \ubca0\ub3cc\ub9ac\uc8fc\ub9d9(\uc5d4\ud2f0\ube44\uc624, \ud56d\uc778\ud14c\uadf8\ub9b0), \uc6b0\uc2a4\ud14c\ud0a4\ub204\ub9d9(\uc2a4\ud154\ub77c\ub77c, \ud56dIL-12\/23), \uadf8\ub9ac\uace0 \ud1a0\ud30c\uc2dc\ud2f0\ub2d9(\uc824\uc794\uc988) \uac19\uc740 JAK \uc5b5\uc81c\uc81c\uae4c\uc9c0, \ud2b9\uc815 \uc5fc\uc99d \uacbd\ub85c\ub97c \uc815\ubc00\ud558\uac8c \ucc28\ub2e8\ud558\ub294 \uc57d\ubb3c\uc774 \ucc28\ub840\ub85c \ub3c4\uc785\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc911\ub4f1\uc99d-\uc911\uc99d \ud658\uc790\uc758 \uce58\ub8cc \ud48d\uacbd\uc744 \ud06c\uac8c \ubc14\uafd4 \ub193\uc740 \uc9c4\ubcf4\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\uc758 \ud6a8\uacfc\uac00 \ub5a8\uc5b4\uc9c0\ub294 \ud604\uc2e4<\/h3>\n\n\n\n

                    \ubb38\uc81c\ub294 \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\uc5d0 \ub450 \uac00\uc9c0 \ubcbd\uc774 \uc788\ub2e4\ub294 \uc810\uc785\ub2c8\ub2e4. \uccab\uc9f8\ub294 1\ucc28 \ubb34\ubc18\uc751\uc73c\ub85c, \uccab \ubc88\uc9f8 \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\uc5d0 \ucda9\ubd84\ud55c \ubc18\uc751\uc744 \ubcf4\uc774\uc9c0 \uc54a\ub294 \ud658\uc790\uac00 \uc57d\ubb3c\uc5d0 \ub530\ub77c 20~40%\uc5d0 \uc774\ub985\ub2c8\ub2e4. \uc774\uc720\ub294 \uc644\uc804\ud788 \ubc1d\ud600\uc9c0\uc9c0 \uc54a\uc558\uc73c\ub098 \ud658\uc790\ub9c8\ub2e4 \uc5fc\uc99d\uc744 \uc8fc\ub3c4\ud558\ub294 \uacbd\ub85c\uac00 \ub2e4\ub974\uae30 \ub54c\ubb38\uc774\ub77c\uace0 \ucd94\uc815\ub429\ub2c8\ub2e4. \ub458\uc9f8\ub294 2\ucc28 \ubb34\ubc18\uc751, \uc989 \ud6a8\uacfc\uc758 \uc18c\uc2e4\uc785\ub2c8\ub2e4. \ucc98\uc74c\uc5d0\ub294 \uc798 \ub4e3\ub358 \uc57d\uc774 \uc218\uac1c\uc6d4\uc5d0\uc11c \uc218\ub144\uc5d0 \uac78\uccd0 \uc810\uc810 \ud6a8\uacfc\uac00 \ub5a8\uc5b4\uc9c0\ub294 \ud604\uc0c1\uc73c\ub85c, \ud56d\uc57d\ubb3c\ud56d\uccb4\uac00 \ud615\uc131\ub418\uac70\ub098 \uc9c8\ubcd1\uc744 \uc8fc\ub3c4\ud558\ub294 \uc5fc\uc99d \uacbd\ub85c \uc790\uccb4\uac00 \uc2dc\uac04\uc774 \uc9c0\ub098\uba74\uc11c \ubc14\ub00c\ub294 \uac83\uc774 \uc6d0\uc778\uc73c\ub85c \uc54c\ub824\uc838 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc5f0\uad6c\ub4e4\uc740 \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\uc5d0 \ubc18\uc751\ud55c \ud658\uc790\uc758 \uc57d 30~40%\uac00 1\ub144 \uc774\ub0b4\uc5d0 2\ucc28 \ubb34\ubc18\uc751\uc744 \uacbd\ud5d8\ud55c\ub2e4\uace0 \ubcf4\uace0\ud569\ub2c8\ub2e4. \ub2e4\uc74c \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\ub85c \ubc14\uafd4\ub3c4 \ubc18\uc751\ub960\uc740 \ub5a8\uc5b4\uc9c0\uace0, 3\ubc88\uc9f8, 4\ubc88\uc9f8\ub85c \uac08\uc218\ub85d \uc751\ub2f5\ub960\uc740 \ub354 \ub0ae\uc544\uc9d1\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \ub300\uc7a5 \uc808\uc81c\uc220\uc774\ub77c\ub294 \ub9c8\uc9c0\ub9c9 \uc120\ud0dd<\/h3>\n\n\n\n

                    \ub0b4\uacfc\uc801 \uce58\ub8cc\ub97c \ubaa8\ub450 \uc2dc\ub3c4\ud574\ub3c4 \ud1b5\uc81c\ub418\uc9c0 \uc54a\ub294 \uacbd\uc6b0, \ud55c\uad6d\uc5d0\uc11c\ub3c4 \ub9c8\uc9c0\ub9c9 \uc120\ud0dd\uc9c0\ub85c \ub300\uc7a5 \uc808\uc81c\uc220(\ud68c\uc7a5\ub0ad-\ud56d\ubb38 \ubb38\ud569\uc220\uc744 \ub3d9\ubc18\ud558\ub294 \uacbd\uc6b0\uac00 \ub9ce\uc74c)\uc774 \uace0\ub824\ub429\ub2c8\ub2e4. \ud06c\ub860\ubcd1\uacfc \ub2ec\ub9ac \uada4\uc591\uc131 \ub300\uc7a5\uc5fc\uc740 \ub300\uc7a5\uc5d0\ub9cc \ubc1c\uc0dd\ud558\ub294 \uc9c8\ud658\uc774\ubbc0\ub85c, \ub300\uc7a5\uc744 \uc81c\uac70\ud558\uba74 \ud615\uc2dd\uc801\uc73c\ub85c \ubcd1 \uc790\uccb4\ub294 \uc0ac\ub77c\uc9d1\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc774\ub294 \ubd84\uba85\ud788 \uc720\ud6a8\ud55c \uc120\ud0dd\uc785\ub2c8\ub2e4. \uc911\uc99d \ub09c\uce58\uc131 \uc0ac\ub840\uc5d0\uc11c\ub294 \uc801\uc808\ud55c \uae38\uc774 \ub420 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \ub2e4\ub9cc \ud070 \uc218\uc220\uc774\uba70 \ud68c\uc7a5\ub0ad \uc790\uccb4\uc5d0 \uc5fc\uc99d\uc774 \uc0dd\uae30\ub294 \ud68c\uc7a5\ub0ad\uc5fc(pouchitis)\uc774\ub77c\ub294 \uc0c8\ub85c\uc6b4 \ubb38\uc81c\uac00 \ubc1c\uc0dd\ud560 \uc218 \uc788\uace0, \uac00\uc784\uae30 \uc5ec\uc131\uc758 \uacbd\uc6b0 \uc784\uc2e0 \uac00\ub2a5\uc131\uc5d0 \uc601\ud5a5\uc774 \ub17c\uc758\ub429\ub2c8\ub2e4. \ubc30\ubcc0 \uae30\ub2a5\uc758 \ubcc0\ud654\uc5d0 \uc801\uc751\ud558\ub294 \ub370 \uc2dc\uac04\uc774 \uac78\ub9ac\uba70, \uc77c\ubd80 \ud658\uc790\ub294 \uc7a5\uae30\uc801\uc73c\ub85c \ub9cc\uc871\uc2a4\ub7fd\uc9c0 \ubabb\ud55c \ud68c\uc7a5\ub0ad \uae30\ub2a5\uc5d0 \uc5b4\ub824\uc6c0\uc744 \uacaa\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    “\ub2e4\uc74c \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\ub0d0, \uc218\uc220\uc774\ub0d0”\uc758 \uc591\uc790\ud0dd\uc77c \uc0ac\uc774\uc5d0\uc11c, \ub9cc\uc57d \uadf8 \uc0ac\uc774\ub97c \uba54\uc6b8 \uc218 \uc788\ub294 “\uadfc\ubcf8 \uc5fc\uc99d\uc744 \uc0dd\ubb3c\ud559\uc801\uc73c\ub85c \uac00\ub77c\uc549\ud788\ub294” \uc81c3\uc758 \uae38\uc774 \uc788\ub2e4\uba74 \uac80\ud1a0\ud558\uace0 \uc2f6\ub2e4\uace0 \uc0dd\uac01\ud558\ub294 \ud658\uc790\uac00 \ub9ce\uc740 \uac83\uc740 \uc790\uc5f0\uc2a4\ub7ec\uc6b4 \uc77c\uc785\ub2c8\ub2e4. \uadf8 \ube48\uc790\ub9ac\ub97c \ucc44\uc6b0\ub294 \uac00\ub2a5\uc131 \uc911 \ud558\ub098\uac00 \uac04\uc5fd \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc785\ub2c8\ub2e4. <\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \uac04\uc5fd \uc904\uae30\uc138\ud3ec\uac00 \uada4\uc591\uc131 \ub300\uc7a5\uc5fc\uc5d0 \uc791\uc6a9\ud558\ub294 \uc138 \uac00\uc9c0 \uba54\ucee4\ub2c8\uc998<\/mark><\/h2>\n\n\n
                    \n
                    \"\uada4\uc591\uc131
                    \uac04\uc5fd \uc904\uae30\uc138\ud3ec\ub294 \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\uac00 \ud558\ub098\uc758 \ubd84\uc790\ub97c \ucc28\ub2e8\ud558\ub294 \uac83\uacfc \ub2ec\ub9ac, \uada4\uc591\uc131 \ub300\uc7a5\uc5fc\uc5d0 \ub3d9\uc2dc\uc5d0 \uc138 \uac00\uc9c0 \uacbd\ub85c\ub85c \uc791\uc6a9\ud569\ub2c8\ub2e4.<\/figcaption><\/figure>\n<\/div>\n\n\n

                    \uc798\ubabb \ucf1c\uc9c4 \uba74\uc5ed \uacf5\uaca9\uc744 \uac00\ub77c\uc549\ud78c\ub2e4<\/h3>\n\n\n\n

                    \uac04\uc5fd \uc904\uae30\uc138\ud3ec(\uc601\uc5b4 \uc57d\uc790\ub85c MSC)\ub294 \uace8\uc218, \uc9c0\ubc29\uc870\uc9c1, \uc81c\ub300 \uc870\uc9c1\uc5d0 \uc790\uc5f0\uc801\uc73c\ub85c \uc874\uc7ac\ud558\ub294 \uc138\ud3ec\uc785\ub2c8\ub2e4. \uc624\ub79c \uc5f0\uad6c\ub97c \ud1b5\ud574 \uba74\uc5ed \uc870\uc808 \ub2a5\ub825\uc774 \uc798 \uc54c\ub824\uc838 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uada4\uc591\uc131 \ub300\uc7a5\uc5fc \ud658\uc790\uc5d0\uac8c \uc815\ub9e5\uc73c\ub85c \uc8fc\uc785\ud558\uba74, MSC\ub294 \ud608\ub958\ub97c \ub530\ub77c \uc5fc\uc99d\uc774 \uc788\ub294 \uc7a5\uc18c, \uc989 \ub300\uc7a5 \uc810\ub9c9\uc73c\ub85c \ubaa8\uc774\ub294 \uc131\uc9c8\uc774 \uc788\uc2b5\ub2c8\ub2e4. \uadf8\uacf3\uc5d0\uc11c \uacf5\uaca9 \uc5ed\ud560\uc758 T \uc138\ud3ec \ud65c\ub3d9\uc744 \uac00\ub77c\uc549\ud788\ub294 \uc2e0\ud638\ub97c \ub0b4\ubcf4\ub0b4\uace0, \ub3d9\uc2dc\uc5d0 “\uba74\uc5ed\uc758 \uc870\uc815\uc790”\ub77c \ubd80\ub97c \uc218 \uc788\ub294 \uc870\uc808 T \uc138\ud3ec(Treg)\ub97c \uc99d\uc2dd\uc2dc\ud0b5\ub2c8\ub2e4. \uacf5\uaca9 \uc138\ud3ec\ub294 \ub204\uadf8\ub7ec\ub728\ub9ac\uace0, \uc870\uc815 \uc138\ud3ec\ub294 \ub298\ub9b0\ub2e4. \uc774 \ub450 \ubc29\ud5a5\uc758 \uc791\uc6a9\uc774, \ud55c \ubd84\uc790\ub97c \uc815\ud655\ud788 \ucc28\ub2e8\ud558\ub294 \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\uc640 \uadfc\ubcf8\uc801\uc73c\ub85c \ub2e4\ub978 \ubd80\ubd84\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc774 \uba74\uc5ed\uc744 \ub2e4\uc2dc \uc870\uc728\ud558\ub294 \uc791\uc6a9\uc740 \uada4\uc591\uc131 \ub300\uc7a5\uc5fc \uc678\uc758 \uc790\uac00\uba74\uc5ed\uc9c8\ud658\uc5d0\uc11c\ub3c4 \uc5f0\uad6c\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ub958\ub9c8\ud2f0\uc2a4 \uad00\uc808\uc5fc\uc758 \uc904\uae30\uc138\ud3ec \uce58\ub8cc\ub3c4 \uac19\uc740 \uba74\uc5ed \uc870\uc808 \uba54\ucee4\ub2c8\uc998\uc744 \ud1a0\ub300\ub85c \ud558\uba70, \uc9c4\ub2e8\uba85\uc740 \ub2ec\ub77c\ub3c4 \uadfc\ubcf8\uc758 \uba74\uc5ed \uad50\ub780\uc774\ub77c\ub294 \uc8fc\uc81c\ub294 \uacf5\uc720\ub429\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \ub300\uc7a5 \uc810\ub9c9 \ub0b4\ubd80\uc5d0\uc11c \uc9c1\uc811 \uc5fc\uc99d\uc744 \ub0ae\ucd98\ub2e4<\/h3>\n\n\n\n

                    \ub450 \ubc88\uc9f8 \uba54\ucee4\ub2c8\uc998\uc740 \uc5fc\uc99d \ud604\uc7a5\uc5d0\uc11c\uc758 \uc9c1\uc811 \uc791\uc6a9\uc785\ub2c8\ub2e4. MSC\ub294 \ub300\uc7a5 \uc810\ub9c9 \ub0b4\ubd80\uc5d0\uc11c TNF-\u03b1, IL-6, IL-1 \uac19\uc740 \uc5fc\uc99d\uc131 \uc0ac\uc774\ud1a0\uce74\uc778\uc758 \uad6d\uc18c \uc0dd\uc131\uc744 \uc5b5\uc81c\ud569\ub2c8\ub2e4. \uc774\ub294 \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\uac00 \ud608\ub958 \uc911\uc5d0\uc11c \uac19\uc740 \ubd84\uc790\ub97c \ucc28\ub2e8\ud558\ub294 \uac83\uacfc \ub2ec\ub9ac, MSC\uac00 \uc5fc\uc99d\uc774 \uc77c\uc5b4\ub098\ub294 \uc810\ub9c9 \ub0b4\ubd80\uc5d0\uc11c\ubd80\ud130 \uc548\ucabd\uc73c\ub85c \uc791\uc6a9\ud558\ub294 \uadf8\ub9bc\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ub610\ud55c \ud65c\ub3d9\uae30\uc5d0 \uc870\uc9c1\uc744 \uc190\uc0c1\uc2dc\ud0a4\ub294 \uc5fc\uc99d\uc131 \ub300\uc2dd\uc138\ud3ec\uc640 \ud638\uc911\uad6c\uc758 \ud65c\ub3d9\uc744 \uac00\ub77c\uc549\ud788\uace0, \uc870\uc9c1 \ubcf5\uad6c \ucabd\uc758 \ub300\uc2dd\uc138\ud3ec\ub85c \uc804\ud658\uc744 \ucd09\uc9c4\ud558\ub294 \uc791\uc6a9\ub3c4 \ubcf4\uace0\ub418\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uadf8 \uacb0\uacfc \ub300\uc7a5 \uc810\ub9c9 \uc804\uccb4\uc758 \uc5fc\uc99d \ud1a4\uc774 \ub0ae\uc544\uc9c0\uba74\uc11c \ucd9c\ud608, \ubcc0\uc758 \uc808\ubc15\uac10, \ubcf5\ud1b5 \uac19\uc740 \uac00\uc7a5 \uc77c\uc0c1\uc5d0 \uc601\ud5a5\uc744 \uc8fc\ub294 \uc99d\uc0c1\uc774 \ud638\uc804\ub420 \uac00\ub2a5\uc131\uc774 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \ub300\uc7a5 \uc810\ub9c9\uc758 \ud68c\ubcf5\uc744 \ub3d5\ub294\ub2e4<\/h3>\n\n\n\n

                    \uc138 \ubc88\uc9f8\ub294 \uc870\uc9c1 \ud68c\ubcf5 \uc9c0\uc6d0\uc785\ub2c8\ub2e4. MSC\ub294 \ub2e4\uc591\ud55c \uc131\uc7a5\uc778\uc790\ub97c \ubd84\ube44\ud558\uc5ec \uae4a\uc774 \ud615\uc131\ub41c \uada4\uc591 \ubd80\uc704\uc758 \uc0c1\ud53c\uc138\ud3ec \uc0dd\uc874\uacfc \ubcf5\uad6c\ub97c \ud6c4\ubc29\uc5d0\uc11c \ub3d5\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ucd5c\uadfc \ud55c\uad6d\uacfc \ud574\uc678\uc758 \uc9c4\ub8cc \uc9c0\uce68\uc740 \uada4\uc591\uc131 \ub300\uc7a5\uc5fc\uc758 \uce58\ub8cc \ubaa9\ud45c\ub97c \ub2e8\uc21c\ud55c \uc99d\uc0c1 \uc644\ud654\uc5d0\uc11c “\uc810\ub9c9 \uce58\uc720”, \uc989 \ub300\uc7a5\ub0b4\uc2dc\uacbd\uc0c1 \uada4\uc591\uacfc \ubbf8\ub780\uc774 \ud638\uc804\ub41c \uc0c1\ud0dc\ub97c \ub2ec\uc131\ud558\ub294 \uac83\uc73c\ub85c \uc62e\uaca8\uac00\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc810\ub9c9 \uce58\uc720\ub97c \ub2ec\uc131\ud55c \ud658\uc790\uac00 \uc7a5\uae30 \uc608\ud6c4\uac00 \uc88b\ub2e4\ub294 \uc5f0\uad6c \uacb0\uacfc\uac00 \ub204\uc801\ub418\uace0 \uc788\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4. MSC\uac00 \ud30c\uad34\ub41c \ub300\uc7a5\uc744 \ub2e4\uc2dc \ub9cc\ub4dc\ub294 \uac83\uc740 \uc544\ub2c8\uc9c0\ub9cc, \ud68c\ubcf5\uc774 \uc77c\uc5b4\ub098\uae30 \uc26c\uc6b4 \ud658\uacbd\uc744 \ub9cc\ub4dc\ub294 \ub370 \uae30\uc5ec\ud560 \uac00\ub2a5\uc131\uc774 \uc788\ub2e4\uace0 \ud3c9\uac00\ub429\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \uada4\uc591\uc131 \ub300\uc7a5\uc5fc\uc5d0 \ub300\ud55c \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc758 \uc784\uc0c1 \uadfc\uac70<\/mark><\/h2>\n\n\n
                    \n
                    \"\uada4\uc591\uc131
                    Mayo \uc810\uc218(\uada4\uc591\uc131 \ub300\uc7a5\uc5fc \ud65c\ub3d9\uc131\uc744 \uce21\uc815\ud558\ub294 \ud45c\uc900 \uc9c0\ud45c)\ub294 \ub3d9\uc885 \uac04\uc5fd \uc904\uae30\uc138\ud3ec \uce58\ub8cc \ud6c4 \uc720\uc758\ud558\uac8c \uac10\uc18c\ud55c \uac83\uc73c\ub85c \ubcf4\uace0\ub429\ub2c8\ub2e4. \ucd9c\ucc98: Hu et al., Experimental and Therapeutic Medicine, 2016.<\/figcaption><\/figure>\n<\/div>\n\n\n

                    \uada4\uc591\uc131 \ub300\uc7a5\uc5fc\uc744 \ub300\uc0c1\uc73c\ub85c \ud55c \uc8fc\uc694 \uc784\uc0c1\uc2dc\ud5d8<\/h3>\n\n\n\n

                    \uada4\uc591\uc131 \ub300\uc7a5\uc5fc\uc5d0 \ub300\ud55c \uac04\uc5fd \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc758 \uc784\uc0c1 \uadfc\uac70\ub294, \ub958\ub9c8\ud2f0\uc2a4 \uad00\uc808\uc5fc\uc774\ub098 \uace8\uad00\uc808\uc5fc\uc5d0 \ube44\ud558\uba74 \uc0c1\ub300\uc801\uc73c\ub85c \uc0c8\ub85c\uc6b4 \ubd84\uc57c\uc9c0\ub9cc, \uc5ec\ub7ec \ud3b8\uc758 \ub17c\ubb38\uc774 \ub3d9\ub8cc \ud3c9\uac00\ub97c \uac70\uccd0 \ubc1c\ud45c\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    Hu\uc640 \ub3d9\ub8cc\ub4e4\uc758 \uc5f0\uad6c(Experimental and Therapeutic Medicine, 2016)\ub294 \uae30\uc874 \uce58\ub8cc\ub85c \ucda9\ubd84\ud55c \ud6a8\uacfc\ub97c \uc5bb\uc9c0 \ubabb\ud55c \uc911\ub4f1\uc99d-\uc911\uc99d \uada4\uc591\uc131 \ub300\uc7a5\uc5fc \ud658\uc790\ub97c \ub300\uc0c1\uc73c\ub85c, \ub3d9\uc885 \uc81c\ub300 \uc720\ub798 \uac04\uc5fd \uc904\uae30\uc138\ud3ec\uc758 \uc815\ub9e5 \uc8fc\uc785\uc744 \ud3c9\uac00\ud588\uc2b5\ub2c8\ub2e4. \uce58\ub8cc \ud6c4 Mayo \uc810\uc218(\uada4\uc591\uc131 \ub300\uc7a5\uc5fc\uc758 \uc9c8\ubcd1 \ud65c\ub3d9\uc131\uc744 \ub098\ud0c0\ub0b4\ub294 \ubcf5\ud569 \uc9c0\ud45c\ub85c, \ubc30\ubcc0 \ud69f\uc218\u00b7\uc9c1\uc7a5 \ucd9c\ud608\u00b7\ub0b4\uc2dc\uacbd \uc18c\uacac\u00b7\uc758\uc0ac\uc758 \uc885\ud569 \ud3c9\uac00\ub97c \uc870\ud569\ud569\ub2c8\ub2e4)\uc640 \uc5fc\uc99d \uc9c0\ud45c\uc778 C-\ubc18\uc751\uc131 \ub2e8\ubc31(CRP)\uc774 \uc720\uc758\ud558\uac8c \uac1c\uc120\ub418\uc5c8\ub2e4\uace0 \ubcf4\uace0\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    Lazebnik \ub4f1\uc758 \uc5f0\uad6c\ub294 \uada4\uc591\uc131 \ub300\uc7a5\uc5fc\uc744 \ud3ec\ud568\ud55c \uc5fc\uc99d\uc131 \uc7a5 \uc9c8\ud658 \ud658\uc790\uc5d0\uac8c MSC \uce58\ub8cc\ub97c \uc2dc\ud589\ud588\uace0, \ucd94\uc801 \ud3c9\uac00\uc5d0\uc11c \uc9c8\ubcd1 \ud65c\ub3d9\uc131 \uc810\uc218\uc758 \uac1c\uc120\uc774 \ud655\uc778\ub418\uc5c8\uc2b5\ub2c8\ub2e4. Liang \ub4f1\uc758 \uc5f0\uad6c(Gut, 2012)\uc5d0\uc11c\ub294 \ub09c\uce58\uc131 \uc5fc\uc99d\uc131 \uc7a5 \uc9c8\ud658 \ud658\uc790\uc5d0 \ub300\ud55c \ub3d9\uc885 \uace8\uc218 \uc720\ub798 MSC \uce58\ub8cc\uac00 \uc911\ub300\ud55c \uc774\uc0c1\ubc18\uc751 \uc5c6\uc774 \uc9c8\ubcd1 \ud65c\ub3d9\uc131 \uc800\ud558\ub97c \ubcf4\uc600\ub2e4\uace0 \ubcf4\uace0\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc5fc\uc99d\uc131 \uc7a5 \uc9c8\ud658\uc5d0\uc11c \uac00\uc7a5 \ud655\ub9bd\ub41c \uc904\uae30\uc138\ud3ec \uce58\ub8cc\ub85c\ub294 ADMIRE-CD \uc784\uc0c1\uc2dc\ud5d8(Panes \ub4f1)\uc5d0\uc11c \ud3c9\uac00\ub41c Cx601(\ub2e4\ubc14\ub4dc\uc2a4\ud2b8\ub85c\uc140)\uc774 \uc788\uc2b5\ub2c8\ub2e4. \uc774\ub294 \ud06c\ub860\ubcd1\uc758 \ubcf5\ud569 \ud56d\ubb38\uc8fc\uc704 \ub204\uacf5\uc744 \ub300\uc0c1\uc73c\ub85c \ud55c \uce58\ub8cc\ub85c, \uada4\uc591\uc131 \ub300\uc7a5\uc5fc\uc758 \uc7a5\uad00 \ubcd1\ubcc0\uc774 \uc9c1\uc811\uc801\uc778 \ub300\uc0c1\uc740 \uc544\ub2d9\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \ubb34\uc791\uc704 \ub300\uc870 \uc2dc\ud5d8\uc5d0\uc11c \ub3d9\uc885 MSC \uce58\ub8cc\uac00 \uc5fc\uc99d\uc131 \uc7a5 \uc9c8\ud658 \uc601\uc5ed\uc5d0\uc11c \uc784\uc0c1\uc801\uc73c\ub85c \uc758\ubbf8 \uc788\ub294 \ubcc0\ud654\ub97c \ub9cc\ub4e4\uc5b4\ub0bc \uc218 \uc788\ub2e4\ub294 \uc810\uc744 \ubcf4\uc5ec \uc900 \uc911\uc694\ud55c \ub370\uc774\ud130\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc5ec\ub7ec \uc5f0\uad6c\ub97c \uc885\ud569\ud55c \ubd84\uc11d\uc5d0\uc11c, \ud65c\ub3d9\uc131 \uc5fc\uc99d\uc131 \uc7a5 \uc9c8\ud658\uc5d0 \ub300\ud55c \uac04\uc5fd \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc758 \uc784\uc0c1 \uc751\ub2f5\ub960\uc740 \ub300\uccb4\ub85c 40~50% \uc218\uc900\uc774\uba70, \ucd94\uc801 \ub0b4\uc2dc\uacbd\uc5d0\uc11c \uc810\ub9c9 \uce58\uc720\uac00 \uc77c\uc815 \ube44\uc728\uc758 \ud658\uc790\uc5d0\uac8c\uc11c \uad00\ucc30\ub429\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \uc22b\uc790\ub97c \uc77c\uc0c1\uc758 \ubcc0\ud654\ub85c \uc62e\uae30\uba74<\/h3>\n\n\n\n

                    40~50%\ub77c\ub294 \uc751\ub2f5\ub960\uc744 \ud658\uc790\uc758 \uc77c\uc0c1 \uc5b8\uc5b4\ub85c \uc62e\uaca8 \ubd05\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc774 \uc751\ub2f5\ub960\uc740 \uc774\ubbf8 \uae30\uc874 \uce58\ub8cc\ub85c \ucda9\ubd84\ud55c \ud6a8\uacfc\ub97c \uc5bb\uc9c0 \ubabb\ud55c \ud658\uc790\ub97c \ub300\uc0c1\uc73c\ub85c \ud55c \uacb0\uacfc\ub77c\ub294 \uc810\uc744 \uc78a\uc5b4\uc11c\ub294 \uc548 \ub429\ub2c8\ub2e4. “\uc644\uce58”\uac00 \uc544\ub2c8\ub77c “\uc784\uc0c1 \uc751\ub2f5”, \uc989 \uc9c8\ubcd1 \ud65c\ub3d9\uc131\uc774 \uc77c\uc815 \uc218\uc900 \uc774\uc0c1 \ub0ae\uc544\uc9c4 \uc0c1\ud0dc\ub97c \uac00\ub9ac\ud0b5\ub2c8\ub2e4. \uc751\ub2f5\ud55c \ud658\uc790\ub3c4 \uc5b4\ub5a4 \ud615\ud0dc\ub85c\ub4e0 \uc720\uc9c0 \uce58\ub8cc\ub97c \uacc4\uc18d\ud558\ub294 \uac83\uc774 \uc77c\ubc18\uc801\uc774\uba70, \ud5a5\ud6c4 \uc7ac\ubc1c \uac00\ub2a5\uc131\uc740 \ub0a8\uc544 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ud604\uc2e4\uc801\uc778 \uadf8\ub9bc\uc740 \uc774\ub807\uc2b5\ub2c8\ub2e4. \uce58\ub8cc \ud6c4 3~6\uac1c\uc6d4\uc5d0 \uac78\uccd0 \ubc30\ubcc0 \ud69f\uc218\uac00 \uc11c\uc11c\ud788 \uc904\uc5b4\ub4e4\uace0, \ud608\ubcc0\uc774 \uc774\uc804\ubcf4\ub2e4 \uba85\ud655\ud788 \uac10\uc18c\ud558\uba70, \uc5d0\ub108\uc9c0\uac00 \ud68c\ubcf5\ub418\uace0, CRP\uc640 \ubcc0 \uce7c\ud504\ub85c\ud14d\ud2f4 \uac19\uc740 \uc5fc\uc99d \uc9c0\ud45c\uac00 \ub5a8\uc5b4\uc9d1\ub2c8\ub2e4. \ub0b4\uc2dc\uacbd\uc801 \ud638\uc804\uc740 6\uac1c\uc6d4 \uc774\ud6c4\uc5d0 \ub098\ud0c0\ub098\ub294 \uacbd\uc6b0\uac00 \ub9ce\uc2b5\ub2c8\ub2e4. \ud55c\ud3b8, 40~60%\uc758 \ud658\uc790\ub294 \uc774 \uc218\uc900\uc758 \ud638\uc804\uc744 \uacbd\ud5d8\ud558\uc9c0 \ubabb\ud569\ub2c8\ub2e4. \ub204\uac00 \uc751\ub2f5\ud560\uc9c0\ub97c \uc0ac\uc804\uc5d0 \uc815\ud655\ud558\uac8c \uc608\uce21\ud558\ub294 \ubc29\ubc95\uc740, \ud604\uc7ac\ub85c\uc11c\ub294 \uc874\uc7ac\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc800\ud76c\ub294 \ucd08\uc9c4 \uc0c1\ub2f4\uc5d0\uc11c \ubc18\ub4dc\uc2dc \uc774 \uc218\uce58\ub97c \ud568\uaed8 \uc548\ub0b4\ud569\ub2c8\ub2e4. \uc88b\uc740 \uba74\ub9cc \uc798\ub77c\ub0b8 \uc774\uc57c\uae30\ub294 \ud658\uc790\uc5d0\uac8c \ub3c4\uc6c0\uc774 \ub418\uc9c0 \uc54a\ub294\ub2e4\uace0 \uc0dd\uac01\ud558\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \ub3d9\uc885 \uc81c\ub300 \uc720\ub798 \uc904\uae30\uc138\ud3ec\ub97c \uc0ac\uc6a9\ud558\ub294 \uc774\uc720<\/mark><\/h2>\n\n\n\n

                    \uc790\uae30 \uc138\ud3ec\uc778\uac00, \uac74\uac15\ud55c \ud0c0\uc778\uc758 \uc138\ud3ec\uc778\uac00<\/h3>\n\n\n\n

                    \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc5d0\ub294 \ud658\uc790 \ubcf8\uc778\uc758 \ubab8\uc5d0\uc11c \uc138\ud3ec\ub97c \ucc44\ucde8\ud574 \uc0ac\uc6a9\ud558\ub294 \uc790\uac00 \uce58\ub8cc\uc640, \uac74\uac15\ud55c \uacf5\uc5ec\uc790\uc758 \uc138\ud3ec\ub97c \uc0ac\uc6a9\ud558\ub294 \ub3d9\uc885 \uce58\ub8cc\uac00 \uc788\uc2b5\ub2c8\ub2e4. \uada4\uc591\uc131 \ub300\uc7a5\uc5fc \uac19\uc740 \uc790\uac00\uba74\uc5ed \uc9c8\ud658\uc5d0\uc11c\ub294 \uc774 \uc120\ud0dd\uc774 \uc784\uc0c1\uc801\uc73c\ub85c \uc758\ubbf8\ub97c \uac00\uc9d1\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc790\uac00 \uc138\ud3ec\ub294 \uc774\ub860\uc0c1 \uba74\uc5ed \uac70\ubd80\uc758 \uc6b0\ub824\uac00 \uc5c6\uc2b5\ub2c8\ub2e4. \ub2e4\ub9cc \uc624\ub7ab\ub3d9\uc548 \uc790\uac00\uba74\uc5ed \uc9c8\ud658\uc744 \uc548\uace0 \uc0b4\uc544\uc628 \ud658\uc790\uc758 \ubab8\uc5d0\uc11c \ucc44\ucde8\ud55c \uc138\ud3ec\ub294, \uadf8 \ub9cc\uc131\uc801\uc73c\ub85c \uad50\ub780\ub41c \uba74\uc5ed \ud658\uacbd\uc758 \ud754\uc801\uc744 \uadf8\ub300\ub85c \uc548\uace0 \uc788\uc744 \uac00\ub2a5\uc131\uc774 \uc788\uc2b5\ub2c8\ub2e4. \uc5f0\uad6c\ub4e4\uc740 \uc790\uac00\uba74\uc5ed \uc9c8\ud658\uc744 \uac00\uc9c4 \ud658\uc790\uc5d0\uac8c\uc11c \ucc44\ucde8\ud55c MSC\uac00 \uac74\uac15\ud55c \uacf5\uc5ec\uc790\uc758 MSC\uc640 \ube44\uad50\ud574 \uc99d\uc2dd \ub2a5\ub825\uacfc \uc720\uc775\ud55c \uc2e0\ud638 \ubd84\uc790\uc758 \ubd84\ube44 \ub2a5\ub825\uc774 \ub0ae\uc544\uc9c4 \uacbd\uc6b0\uac00 \uc788\ub2e4\uace0 \ubcf4\uace0\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ub3d9\uc885 \uc81c\ub300 \uc720\ub798 MSC\ub294 \uac74\uac15\ud55c \uc2e0\uc0dd\uc544\uc758 \uc81c\ub300 \uc870\uc9c1(\uc648\ud2bc \uc824\ub9ac\ub77c \ubd80\ub974\ub294 \ubd80\ubd84)\uc5d0\uc11c \ucc44\ucde8\ub41c \uac83\uc785\ub2c8\ub2e4. \ub3d9\uc758\uc11c\ub97c \ubc1b\uc544 \ucd9c\uc0b0 \uc2dc\uc810\uc5d0 \uc218\uc9d1\ub41c \uc5b4\ub9ac\uace0 \ud65c\uc131\uc774 \ub192\uc740 \uc138\ud3ec\ub85c, \uba74\uc5ed \uac70\ubd80\ub97c \uc798 \uc77c\uc73c\ud0a4\uc9c0 \uc54a\ub294 \ud2b9\uc131(\uc800\uba74\uc5ed\uc6d0\uc131)\uc774 \uc788\uc5b4 \ud608\uc5f0\uad00\uacc4\uac00 \uc5c6\ub294 \uc218\ud61c\uc790\uc5d0\uac8c\ub3c4 \uc548\uc804\ud558\uac8c \uc0ac\uc6a9\ud560 \uc218 \uc788\ub2e4\ub294 \uc810\uc774 \uc798 \uc815\ub9ac\ub418\uc5b4 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \ud55c\uad6d\uc758 \uc790\uac00 \uce58\ub8cc \ud658\uacbd\uacfc \ub9d0\ub808\uc774\uc2dc\uc544\uc758 \ub3d9\uc885 \uc81c\ub300 \uc720\ub798 \uce58\ub8cc<\/h3>\n\n\n\n

                    \ud55c\uad6d\uc758 \ud604\uc7ac \ucca8\ub2e8\uc7ac\uc0dd\uc758\ub8cc\ubc95 \uccb4\uacc4\uc5d0\uc11c\ub294 \uc77c\ubd80 \uc790\uac00 \uc138\ud3ec \uae30\ubc18 \uce58\ub8cc\uac00 \uc81c\ud55c\uc801\uc73c\ub85c \ud5c8\uc6a9\ub418\uc5b4 \uc788\uc9c0\ub9cc, \uada4\uc591\uc131 \ub300\uc7a5\uc5fc\uc5d0 \ub300\ud55c \ub3d9\uc885 \uc81c\ub300 \uc720\ub798 MSC \uce58\ub8cc\ub294 \uc815\ucc29 \ub2e8\uacc4\uc5d0 \uc788\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc800\ud76c\uc758 \uac70\uc810\uc740 \ub9d0\ub808\uc774\uc2dc\uc544\uc5d0 \uc788\uc73c\uba70, \ud488\uc9c8\uc774 \uad00\ub9ac\ub41c \ub3d9\uc885 \uc81c\ub300 \uc720\ub798 \uac04\uc5fd \uc904\uae30\uc138\ud3ec\ub97c \uc0ac\uc6a9\ud569\ub2c8\ub2e4. \ubc30\uce58\ub9c8\ub2e4 \uc138\ud3ec \uc0dd\uc874\uc728, \ud45c\uba74 \ub9c8\ucee4, \ud65c\uc131\ub3c4(\ud3ec\ud150\uc2dc)\ub97c \uac80\uc0ac\ud55c \ub4a4 \ud22c\uc5ec\ud558\ub294 \uc2dc\uc2a4\ud15c\uc73c\ub85c, “\ud22c\uc5ec\ub418\ub294 \uc138\ud3ec\uc758 \ud488\uc9c8”\uc774 \ubb38\uc11c\ud654\ub418\uc5b4 \uc788\ub2e4\ub294 \uc810\uc774 \ud2b9\uc9d5\uc785\ub2c8\ub2e4. \uac19\uc740 \uc774\uc720\ub85c \ub958\ub9c8\ud2f0\uc2a4 \uad00\uc808\uc5fc\uc758 \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc5d0\ub3c4 \ub3d9\uc885 \uc81c\ub300 \uc720\ub798 MSC\ub97c \uc0ac\uc6a9\ud569\ub2c8\ub2e4. \uc790\uac00\uba74\uc5ed \uc9c8\ud658\uc774\ub77c\ub294 \uacf5\ud1b5\uc758 \ub9e5\ub77d\uc5d0\uc11c \uc138\ud3ec \uacf5\uae09\uc6d0\uc5d0 \uad00\ud55c \uc0ac\uace0\ubc29\uc2dd\uc740 \uc77c\uad00\ub429\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \uada4\uc591\uc131 \ub300\uc7a5\uc5fc \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc5d0 \ub9de\ub294 \ubd84, \ub9de\uc9c0 \uc54a\ub294 \ubd84<\/mark><\/h2>\n\n\n\n

                    \uce58\ub8cc\uac00 \uc801\ud569\ud55c \ud658\uc790\uc758 \uc804\ud615<\/h3>\n\n\n\n

                    \uc800\ud76c\uac00 7\ub144 \ub3d9\uc548 200\uba85 \uc774\uc0c1\uc758 \ud658\uc790\ub97c \uce58\ub8cc\ud55c \uacbd\ud5d8\uacfc \uacf5\uac1c\ub41c \uc784\uc0c1 \ub370\uc774\ud130\ub97c \uc885\ud569\ud558\uba74, \uada4\uc591\uc131 \ub300\uc7a5\uc5fc MSC \uce58\ub8cc\uc5d0\uc11c \uc131\uacfc\uac00 \ub098\uc624\uae30 \uc26c\uc6b4 \ud658\uc790\uc5d0\uac8c\ub294 \uacf5\ud1b5\ub41c \ud2b9\uc131\uc774 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ucd5c\uadfc \ub300\uc7a5\ub0b4\uc2dc\uacbd\uc73c\ub85c \uada4\uc591\uc131 \ub300\uc7a5\uc5fc\uc758 \uc9c4\ub2e8\uc774 \ud655\uc778\ub418\uc5b4 \uc788\uace0, CRP\ub098 \ubcc0 \uce7c\ud504\ub85c\ud14d\ud2f4 \uac19\uc740 \uc5fc\uc99d \uc9c0\ud45c\uac00 \uc0c1\uc2b9\ud574 \uc788\ub294 \uc911\ub4f1\uc99d \uc774\uc0c1\uc758 \ud65c\ub3d9\uc131\uc744 \uac00\uc9c4 \ubd84. \uc801\uc5b4\ub3c4 \ud558\ub098, \uac00\ub2a5\ud558\uba74 \ub458 \uc774\uc0c1\uc758 \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\ub97c \uc2dc\ub3c4\ud588\uc74c\uc5d0\ub3c4 \ucda9\ubd84\ud55c \uad00\ud574\ub97c \uc720\uc9c0\ud558\uc9c0 \ubabb\ud55c \ubd84, \ub610\ub294 \ud604\uc7ac \uce58\ub8cc\uc758 \ubd80\uc791\uc6a9\uc73c\ub85c \uc77c\uc0c1\uc5d0 \uc601\ud5a5\uc744 \ubc1b\uace0 \uc788\ub294 \ubd84. \ud604\uc7ac \uc785\uc6d0 \uce58\ub8cc\uac00 \ud544\uc694\ud55c \uc911\uc99d \uae09\uc131\uae30\ub294 \uc544\ub2d0 \uac83, \ud65c\ub3d9\uc131\uc758 \uc911\uc99d \uac10\uc5fc, \uce58\ub8cc\ubc1b\uc9c0 \uc54a\uc740 \uc554 \uac19\uc740 \uae08\uae30 \uc0ac\ud56d\uc774 \uc5c6\uc744 \uac83. \uadf8\ub9ac\uace0 \uc644\uce58\ub97c \ubcf4\uc7a5\ud558\ub294 \uce58\ub8cc\uac00 \uc544\ub2c8\ub77c, \ud638\uc804\uc774 \uc788\ub2e4\uba74 \uc218\uac1c\uc6d4\uc5d0 \uac78\uccd0 \uc11c\uc11c\ud788 \ub098\ud0c0\ub09c\ub2e4\ub294 \uc810\uc744 \ud568\uaed8 \uc774\ud574\ud574 \uc8fc\uc2e4 \uc218 \uc788\ub294 \ubd84. \uc774\ub7f0 \uc870\uac74\uc774 \uac16\ucdb0\uc9c8 \ub54c, \uc800\ud76c\ub294 \uce58\ub8cc\ub97c \uad8c\uc720\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \uce58\ub8cc\uac00 \ub9de\uc9c0 \uc54a\ub294 \ubd84\uc758 \uc804\ud615<\/h3>\n\n\n\n

                    \ubc18\uba74, \uc800\ud76c\uac00 \uc815\uc9c1\ud558\uac8c “\uc774 \uce58\ub8cc\ub294 \ub9de\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4”\ub77c\uace0 \ub9d0\uc500\ub4dc\ub9ac\ub294 \uacbd\uc6b0\ub3c4 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ud604\uc7ac \uc911\uc99d \uae09\uc131\uae30\uc5d0 \uc788\uace0 \ube48\ubc88\ud55c \ud608\ubcc0, \ubc1c\uc5f4, \ub3c5\uc131 \uac70\ub300 \uacb0\uc7a5\uc758 \uc6b0\ub824\uac00 \uc788\ub294 \uc0c1\ud0dc\uc5d0\uc11c\ub294 \uc751\uae09 \uc785\uc6d0 \uce58\ub8cc\uac00 \ud544\uc694\ud558\uba70, \uc11c\uc11c\ud788 \ud6a8\uacfc\uac00 \ub098\ud0c0\ub098\ub294 MSC \uce58\ub8cc\uc758 \uc2dc\uac04 \ucd95\uacfc \ub9de\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \uc7a5\uae30\uac04 \uad11\ubc94\uc704 \uada4\uc591\uc131 \ub300\uc7a5\uc5fc\uc5d0 \uc774\ubbf8 \uace0\ub3c4 \uc774\ud615\uc131 \ub610\ub294 \ub300\uc7a5\uc554\uc774 \ud655\uc778\ub41c \uacbd\uc6b0\uc5d0\ub294 \uba74\uc5ed \uc870\uc808 \uce58\ub8cc\uac00 \uc544\ub2cc \uc678\uacfc\uc801 \uac80\ud1a0\uac00 \uc6b0\uc120\ub418\uc5b4\uc57c \ud569\ub2c8\ub2e4. \ud65c\ub3d9\uc131\uc758 \uc911\uc99d \uac10\uc5fc\uc774 \uc788\ub294 \ubd84, \uc784\uc2e0 \uc911\uc778 \ubd84\uc740 \ub300\uc0c1\uc774 \uc544\ub2d9\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uadf8\ub9ac\uace0 \ud604\uc7ac \uce58\ub8cc\ub85c \uc88b\uc740 \uad00\ud574\uac00 \uc720\uc9c0\ub418\uace0 \uc788\uace0 \ubd80\uc791\uc6a9\ub3c4 \ubc1b\uc544\ub4e4\uc77c \uc218 \uc788\ub294 \uc218\uc900\uc774\ub77c\uba74, MSC \uce58\ub8cc\ub85c \uc5bb\ub294 \ucd94\uac00 \uc774\uc775\uc740 \ube44\uc6a9\uacfc \uc5ec\ud589\uc5d0 \uacac\uc8fc\uc5b4 \uad8c\ud560 \ub9cc\ud55c \uc218\uc900\uc774 \uc544\ub2d0 \uc218 \uc788\ub2e4\uace0 \uc194\uc9c1\ud788 \ub9d0\uc500\ub4dc\ub9bd\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \ud55c \ud658\uc790\uc758 \uce58\ub8cc \uacbd\ud5d8<\/mark><\/h2>\n\n\n\n

                    40\ub300 \ucd08\ubc18 \uc5ec\uc131\uc758 \uc0ac\ub840\ub97c \uc18c\uac1c\ud558\uaca0\uc2b5\ub2c8\ub2e4. 30\ub300 \ucd08\ubc18\uc5d0 \uc804\ub300\uc7a5\ud615 \uada4\uc591\uc131 \ub300\uc7a5\uc5fc\uc744 \uc9c4\ub2e8\ubc1b\uc740 \ud6c4 9\ub144 \ub3d9\uc548 5-ASA, \uba87 \ucc28\ub840\uc758 \ud504\ub808\ub4dc\ub2c8\uc194\ub860 \ucf54\uc2a4(\uc810\ucc28 \uc2a4\ud14c\ub85c\uc774\ub4dc \uc758\uc874\uc131\uc774 \uc0dd\uae30\ub358 \uc0c1\ud0dc\uc600\uc2b5\ub2c8\ub2e4), \uacac\ub514\uae30 \ud798\ub4e0 \uba54\uc2a4\uaebc\uc6c0\uc744 \ub3d9\ubc18\ud55c \uc544\uc790\ud2f0\uc624\ud504\ub9b0, \ub450 \uac00\uc9c0 \ud56d-TNF \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c(\ub450 \ubc88\uc9f8 \uc57d\ubb3c\uc740 \uc57d 1\ub144 \ud6a8\uacfc\ub97c \ubcf4\uc778 \ub4a4 \uc810\ucc28 \ud6a8\uacfc\uac00 \uac10\uc18c\ud588\uc2b5\ub2c8\ub2e4)\ub97c \uac70\uccd0\uc628 \ubd84\uc774\uc5c8\uc2b5\ub2c8\ub2e4. \uc8fc\uce58\uc758\ub294 \uc138 \ubc88\uc9f8 \uc0dd\ubb3c\ud559\uc801 \uc81c\uc81c\uc640 \ud568\uaed8 \ud5a5\ud6c4 \uc218\uc220\uc801 \uac80\ud1a0 \uc774\uc57c\uae30\ub97c \uaebc\ub0b4\uae30 \uc2dc\uc791\ud55c \uc0c1\ud0dc\uc600\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc77c\uc0c1\uc740 \ud654\uc7a5\uc2e4\uae4c\uc9c0\uc758 \uac70\ub9ac\ub97c \uc911\uc2ec\uc73c\ub85c \uc7ac\ubc30\uce58\ub418\uc5b4 \uc788\uc5c8\uc2b5\ub2c8\ub2e4. \uc7ac\ud0dd\uadfc\ubb34\ub294 \uc120\ud0dd\uc774 \uc544\ub2cc \ud544\uc694\uc600\uc2b5\ub2c8\ub2e4. \uc218\uba74 \uc2dc\uac04\uc5d0 \ube44\ub840\ud558\uc9c0 \uc54a\ub294 \ub9cc\uc131 \ud53c\ub85c\uac00 \uc774\uc5b4\uc84c\uace0, \ubcf8\uc778\uc758 \ud45c\ud604\uc73c\ub85c\ub294 “\uc790\uc2e0\uc758 \ubab8\uc774 \uc2e0\ub8b0\ud560 \uc218 \uc5c6\ub294 \ub3d9\ubc18\uc790\uac00 \ub41c \ub290\ub08c”\uc774\ub77c\uace0 \ud588\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ub17c\ubb38\uacfc \uc800\ud76c\uc758 \uc124\uba85\uc744 \uac80\ud1a0\ud55c \ud6c4, 2024\ub144 \ub9d0\ub808\uc774\uc2dc\uc544\uc5d0\uc11c \ub3d9\uc885 \uc81c\ub300 \uc720\ub798 MSC \uc815\ub9e5 \uce58\ub8cc\ub97c \ubc1b\uc73c\uc168\uc2b5\ub2c8\ub2e4. \uc0ac\uc804 \uc0c1\ub2f4\uc5d0\uc11c \uc800\ud76c\ub294 “\uac1c\uc778\uc758 \ubc18\uc751\uc740 \uc608\uce21\ud560 \uc218 \uc5c6\ub2e4”\ub294 \uc810\uacfc “\ud604\uc7ac \ucc98\ubc29\uc758 \uc870\uc815\uc740 \ubc18\ub4dc\uc2dc \uc8fc\uce58\uc758\uc758 \ud310\ub2e8\uc5d0 \ub9e1\uae34\ub2e4”\ub294 \uc810\uc744 \ubd84\uba85\ud788 \ud588\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uccab 6\uc8fc\ub294 \ubcf8\uc778 \ud45c\ud604\uc73c\ub85c “\uc544\ubb34\uac83\ub3c4 \ub2ec\ub77c\uc9c0\uc9c0 \uc54a\uc740 \uac83 \uac19\ub2e4”\uace0 \ub290\ub07c\uc168\uc2b5\ub2c8\ub2e4. 3\uac1c\uc6d4\uc9f8 \ub4e4\uc5b4\uc11c \ubc30\ubcc0 \ud69f\uc218\uac00 \ud558\ub8e8 8~10\ud68c\uc5d0\uc11c 4~5\ud68c\ub85c \uc904\uc5c8\ub2e4\uace0 \ubcf4\uace0\ud558\uc168\uc2b5\ub2c8\ub2e4. \uc624\ub7ab\ub3d9\uc548 \uc774\uc5b4\uc9c4 \uac04\ud5d0\uc801 \uc9c1\uc7a5 \ucd9c\ud608\ub3c4 \uac70\uc758 \uc0ac\ub77c\uc84c\uc2b5\ub2c8\ub2e4. 6\uac1c\uc6d4 \ucd94\uc801\uc5d0\uc11c CRP\ub294 \uc815\uc0c1 \ubc94\uc704\ub85c \ub0b4\ub824\uc654\uace0, \ubcc0 \uce7c\ud504\ub85c\ud14d\ud2f4\ub3c4 \ud06c\uac8c \ud638\uc804\ub418\uc5c8\uc2b5\ub2c8\ub2e4. 8\uac1c\uc6d4\uc9f8 \uc8fc\uce58\uc758\uac00 \uc2dc\ud589\ud55c \ub300\uc7a5\ub0b4\uc2dc\uacbd\uc5d0\uc11c, \uc774\uc804\uc5d0 \ubd84\uba85\ud55c \uc5fc\uc99d\uc774 \ubcf4\uc600\ub358 \ubd80\uc704\uc5d0 \ubd80\ubd84\uc801\uc778 \uc810\ub9c9 \uce58\uc720\uac00 \ud655\uc778\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc720\uc9c0 \uc6a9\ub7c9\uc758 \uba54\uc0b4\ub77c\uc9c4\uc740 \uacc4\uc18d \ubcf5\uc6a9\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \ubcd1\uc774 \uc0ac\ub77c\uc9c4 \uac83\uc740 \uc544\ub2c8\uba70, \ubbf8\ub798\uc5d0 \uc7ac\ubc1c\ud560 \uac00\ub2a5\uc131\ub3c4 \ub0a8\uc544 \uc788\uc2b5\ub2c8\ub2e4. \uadf8\ub7fc\uc5d0\ub3c4 \uac00\uc871 \uc5ec\ud589\uc744 \uacc4\ud68d\ud560 \uc218 \uc788\uac8c \ub418\uc5c8\uace0, \uc8fc 2\ud68c \uc0ac\ubb34\uc2e4 \ucd9c\uadfc\uc744 \uc7ac\uac1c\ud558\uc168\ub2e4\uace0 \ud569\ub2c8\ub2e4. \ubcf8\uc778\uc758 \ud45c\ud604\uc73c\ub85c\ub294 “\uc644\uce58\ub77c\uae30\ubcf4\ub2e4\ub294, \uba87 \ub144 \ub9cc\uc5d0 \ucc98\uc74c\uc73c\ub85c \uc774 \ubcd1\uc774 \uc778\uc0dd\uc5d0\uc11c \ud070 \ubd80\ubd84\uc774 \uc544\ub2cc \uc791\uc740 \ubd80\ubd84\uc774 \ub418\uc5b4 \uc8fc\uc5c8\ub2e4”\ub294 \uac83\uc774\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \u203b \uc774\ub294 \uc2e4\uc81c \uc784\uc0c1 \uacbd\ud5d8\uc5d0 \uae30\ubc18\ud55c \uc0ac\ub840\uc774\uba70, \uac1c\uc778 \uc2dd\ubcc4\uc744 \ud53c\ud558\uae30 \uc704\ud574 \uc77c\ubd80 \ubcc0\uacbd\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uacb0\uacfc\uc5d0\ub294 \uac1c\uc778\ucc28\uac00 \uc788\uc73c\uba70 \ubaa8\ub4e0 \ubd84\uc5d0\uac8c \uac19\uc740 \uacbd\uacfc\ub97c \ubcf4\uc7a5\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \ud22c\uc5ec \ud6c4\uc758 \uc77c\uc0c1\uacfc \ubcc0\ud654\uac00 \ub098\ud0c0\ub098\ub294 \uc2dc\uae30<\/h3>\n\n\n\n

                    \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc758 \uc2e0\uccb4\uc801 \ubd80\ub2f4\uc740 \uac00\ubcbc\uc6b4 \ud3b8\uc785\ub2c8\ub2e4. \uc815\ub9e5 \uc8fc\uc785 \ud6c4 \uace7\ubc14\ub85c \uac78\uc5b4\uc11c \uc219\uc18c\ub85c \ub3cc\uc544\uac08 \uc218 \uc788\ub294 \uc218\uc900\uc785\ub2c8\ub2e4. \uaca9\ub82c\ud55c \uc6b4\ub3d9\uacfc \uc74c\uc8fc\ub294 \uc57d 1\uc8fc\uc77c \uc815\ub3c4 \uc790\uc81c\ud574 \uc8fc\uc2dc\uc9c0\ub9cc, \uadf8 \uc678\uc5d0\ub294 \ud3c9\uc18c\ub300\ub85c \uc0dd\ud65c\ud558\uc2dc\uba74 \ub429\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc800\ud76c\uac00 \ubc18\ubcf5\ud574\uc11c \ub9d0\uc500\ub4dc\ub9ac\ub294 \uac83\uc740 \ubcc0\ud654\uac00 \ub098\ud0c0\ub098\ub294 \ubc29\uc2dd\uc758 \ud2b9\uc9d5\uc785\ub2c8\ub2e4. \uc2a4\ud14c\ub85c\uc774\ub4dc\ucc98\ub7fc \uba70\uce60 \ub9cc\uc5d0 \uc99d\uc0c1\uc774 \uac00\ub77c\uc549\ub294 \uc885\ub958\uc758 \uce58\ub8cc\uac00 \uc544\ub2d9\ub2c8\ub2e4. \ubc30\ubcc0 \ud69f\uc218\uc758 \ubcc0\ud654, \ubcc0\uc758 \uc808\ubc15\uac10\uc758 \ud638\uc804, \uc5d0\ub108\uc9c0 \ud68c\ubcf5\uc740 \ub9ce\uc740 \uacbd\uc6b0 \ud22c\uc5ec \ud6c4 8~16\uc8fc \uc0ac\uc774\uc5d0 \uc11c\uc11c\ud788 \ub098\ud0c0\ub0a9\ub2c8\ub2e4. \ub0b4\uc2dc\uacbd\uc801 \ubcc0\ud654\ub294 \ub098\ud0c0\ub09c\ub2e4\uba74 6\uac1c\uc6d4 \uc774\ud6c4\uc77c \uac00\ub2a5\uc131\uc774 \ub192\uc2b5\ub2c8\ub2e4. \uccab 1\uac1c\uc6d4\uc5d0 \ud070 \ubcc0\ud654\ub97c \uae30\ub300\ud558\uc2dc\uba74 “\ud6a8\uacfc\uac00 \uc5c6\ub294 \uac83\uc774 \uc544\ub2cc\uac00” \ud558\uace0 \uc77c\ucc0d \uacb0\ub860\uc9c0\uc744 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \uc704\ud5d8\uacfc \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uac00 \ud560 \uc218 \uc5c6\ub294 \uc77c<\/mark><\/h2>\n\n\n\n

                    \uc54c\ub824\uc9c4 \ubd80\uc791\uc6a9\uacfc \uadf8 \uad00\ub9ac<\/h3>\n\n\n\n

                    \uc9c0\uae08\uae4c\uc9c0 \uc5fc\uc99d\uc131 \uc7a5 \uc9c8\ud658\uc744 \ub300\uc0c1\uc73c\ub85c \ud55c \uac04\uc5fd \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc758 \uc784\uc0c1\uc2dc\ud5d8\uc5d0\uc11c, \uc548\uc804\uc131 \ud504\ub85c\ud30c\uc77c\uc740 \ub300\uccb4\ub85c \uc591\ud638\ud55c \uac83\uc73c\ub85c \ubcf4\uace0\ub429\ub2c8\ub2e4. \uc774\ub294 “\uc704\ud5d8\uc774 \uc5c6\ub2e4”\ub294 \uc758\ubbf8\uac00 \uc544\ub2c8\ub77c “\ub370\uc774\ud130\uac00 \ubcf4\uc5ec\uc8fc\ub294 \uc0ac\uc2e4”\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uac00\uc7a5 \ud754\ud55c \ubd80\uc791\uc6a9\uc740 \ud22c\uc5ec \ud6c4 24~48\uc2dc\uac04 \uc774\ub0b4\uc758 \ubbf8\uc5f4\ub85c, \uc57d 15%\uc758 \ud658\uc790\uc5d0\uac8c\uc11c \ub098\ud0c0\ub0a9\ub2c8\ub2e4. \uac10\uc5fc\uc774 \uc544\ub2c8\ub77c \uba74\uc5ed\uccb4\uacc4\uac00 \uacf5\uc5ec\uc790 \uc720\ub798 \uc138\ud3ec\ub97c \uc77c\uc2dc\uc801\uc73c\ub85c \uc778\uc2dd\ud55c \ubc18\uc751\uc73c\ub85c \uc5ec\uaca8\uc9d1\ub2c8\ub2e4. \uc77c\uacfc\uc131 \ud53c\ub85c\uac10, \ub450\ud1b5 \ub4f1\ub3c4 \ubcf4\uace0\ub418\uc9c0\ub9cc, \ubaa8\ub450 \ud2b9\ubcc4\ud55c \uce58\ub8cc \uc5c6\uc774 \uba70\uce60 \uc548\uc5d0 \ud638\uc804\ub418\ub294 \uac83\uc774 \uc77c\ubc18\uc801\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ub3d9\uc885 \uc81c\ub300 \uc720\ub798 MSC\ub294 \uba74\uc5ed\uc6d0\uc131\uc774 \ub0ae\ub2e4\ub294 \ud2b9\uc131\uc774 \uc788\uc5b4, \uc9c0\uae08\uae4c\uc9c0\uc758 \uc784\uc0c1 \uacbd\ud5d8\uc5d0\uc11c \uc911\ub300\ud55c \uba74\uc5ed \uac70\ubd80 \ubc18\uc751\uc740 \ubcf4\uace0\ub418\uc9c0 \uc54a\uc558\uc2b5\ub2c8\ub2e4. Cx601\uc744 \ud3ec\ud568\ud55c \uc5fc\uc99d\uc131 \uc7a5 \uc9c8\ud658 \uc601\uc5ed\uc758 \ubb34\uc791\uc704 \ub300\uc870 \uc2dc\ud5d8 \uc804\ubc18\uc5d0\uc11c \uc138\ud3ec \uc790\uccb4\uc5d0 \uae30\uc778\ud55c \uc911\ub300\ud55c \uc774\uc0c1\ubc18\uc751\uc740 \ub4dc\ubb3c\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \ub2e4\ub9cc 3\ub144\uc744 \ucd08\uacfc\ud558\ub294 \uc7a5\uae30 \uc548\uc804\uc131 \ub370\uc774\ud130\ub294 \uc544\uc9c1 \uc138\uacc4\uc801\uc73c\ub85c\ub3c4 \uc81c\ud55c\uc801\uc785\ub2c8\ub2e4. \uc774\ub294 \ud604 \uc2dc\uc810\uc758 \uc815\uc9c1\ud55c \ud55c\uacc4\uc774\uba70, \uc800\ud76c\ub294 \uce58\ub8cc \uc804\uc5d0 \ubc18\ub4dc\uc2dc \uc774 \uc810\uc744 \uc548\ub0b4\ub4dc\ub9bd\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \uc904\uae30\uc138\ud3ec \uce58\ub8cc\ub85c \ud560 \uc218 \uc5c6\ub294 \uc77c<\/h3>\n\n\n\n

                    \ud604\uc2e4\uc801\uc778 \uae30\ub300\uce58\ub97c \uac00\uc9c0\uc2dc\ub294 \uac83\uc740 \uacfc\ub3c4\ud55c \uae30\ub300\ub97c \uac00\uc9c0\uc2dc\ub294 \uac83\ub9cc\ud07c \uc911\uc694\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc904\uae30\uc138\ud3ec \uce58\ub8cc\ub294 \uc18c\ud654\uae30\ub0b4\uacfc\uc758 \uc9c0\uc18d\uc801\uc778 \uc9c4\ub8cc\ub97c \ub300\uccb4\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. MSC \uce58\ub8cc\ub97c \ubc1b\uc73c\uc2e0 \ud6c4\uc5d0\ub3c4 \uc8fc\uce58\uc758\uc758 \uc9c8\ubcd1 \ud65c\ub3d9\uc131 \ubaa8\ub2c8\ud130\ub9c1\uacfc \ud544\uc694\ud55c \uc720\uc9c0 \uc57d\ubb3c\uc740 \uc804\uc81c \uc870\uac74\uc785\ub2c8\ub2e4. \uce58\ub8cc \ud6c4 \ud638\uc804\uc774 \uc788\ub354\ub77c\ub3c4 \uc720\uc9c0 \uc57d\ubb3c\uc744 \uc904\uc77c \uc218 \uc788\ub294\uc9c0\ub294 \uc8fc\uce58\uc758\uc758 \ud310\ub2e8 \uc601\uc5ed\uc774\uba70, \uc800\ud76c\uac00 \uc77c\ubc29\uc801\uc73c\ub85c \uc9c0\uc2dc\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uc904\uae30\uc138\ud3ec \uce58\ub8cc\ub294 \uc774\ubbf8 \uc9c4\ud589\ub41c \uace0\ub3c4 \uc774\ud615\uc131\uc774\ub098 \ub300\uc7a5\uc554\uc744 \uce58\ub8cc\ud560 \uc218 \uc5c6\uc2b5\ub2c8\ub2e4. \uc774\ub4e4\uc774 \ud655\uc778\ub41c \uacbd\uc6b0 \uc678\uacfc\uc801 \uac80\ud1a0\uac00 \ud544\uc694\ud569\ub2c8\ub2e4. \uc911\uc99d \uae09\uc131\uae30\uc5d0\uc11c \uc2e0\uc18d\ud558\uac8c \uc99d\uc0c1\uc744 \uac00\ub77c\uc549\ud600\uc57c \ud558\ub294 \uc0c1\ud669\uc5d0\ub3c4 \uc801\ud569\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \uc778\ud50c\ub9ad\uc2dc\ub9d9 \uad6c\uc870 \uc694\ubc95 \uac19\uc740 \uc785\uc6d0 \uae30\ubc18\uc758 \uc2e0\uc18d \uce58\ub8cc\uac00 \uc6b0\uc120\ub418\uc5b4\uc57c \ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

                    \uadf8\ub9ac\uace0 \ubaa8\ub4e0 \ubd84\uc5d0\uac8c \ud6a8\uacfc\uac00 \uc788\ub294 \uac83\uc740 \uc544\ub2c8\uba70, \ub204\uad6c\uc5d0\uac8c \ud6a8\uacfc\uac00 \uc788\uc744\uc9c0 \uc0ac\uc804\uc5d0 \ud655\uc2e4\ud788 \uc608\uce21\ud560 \uc218 \uc788\ub294 \ubc29\ubc95\uc740 \uc5c6\uc2b5\ub2c8\ub2e4. \uc774 \ub610\ud55c \uc800\ud76c\uac00 \uc194\uc9c1\ud788 \ub9d0\uc500\ub4dc\ub9ac\ub294 \ubd80\ubd84\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                    <\/div>\n\n\n\n

                    \uada4\uc591\uc131 \ub300\uc7a5\uc5fc \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc5d0 \uad00\ud55c \uc790\uc8fc \ubb3b\ub294 \uc9c8\ubb38<\/mark><\/h2>\n\n\n\n
                    \n
                    \n