{"id":24604,"date":"2026-04-27T14:05:35","date_gmt":"2026-04-27T06:05:35","guid":{"rendered":"https:\/\/stemcell-malaysia.com\/?page_id=24604"},"modified":"2026-04-27T14:05:37","modified_gmt":"2026-04-27T06:05:37","slug":"mild-cognitive-impairment","status":"publish","type":"page","link":"https:\/\/stemcell-malaysia.com\/ko\/conditions\/mild-cognitive-impairment\/","title":{"rendered":"\uacbd\ub3c4\uc778\uc9c0\uc7a5\uc560 \uc904\uae30\uc138\ud3ec \uce58\ub8cc | \uc778\uc9c0 \uae30\ub2a5 \uc800\ud558\uac00 \uce58\ub9e4\ub85c \ubc1c\uc804\ud558\uae30 \uc804\uc5d0 \ub2a6\ucd9c \uc218 \uc788\uc744\uae4c?"},"content":{"rendered":"\n

\uacbd\ub3c4\uc778\uc9c0\uc7a5\uc560 \uc904\uae30\uc138\ud3ec \uce58\ub8cc | \uc778\uc9c0 \uae30\ub2a5 \uc800\ud558\uac00 \uce58\ub9e4\ub85c \ubc1c\uc804\ud558\uae30 \uc804\uc5d0 \ub2a6\ucd9c \uc218 \uc788\uc744\uae4c?<\/h1>\n\n\n
\n
\"\uacbd\ub3c4\uc778\uc9c0\uc7a5\uc560
\uacbd\ub3c4\uc778\uc9c0\uc7a5\uc560\uc758 \uc9c4\ud589\uc744 \ub2a6\ucd94\uae30 \uc704\ud574 \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uac00 \ubcf4\ud638\ud558\uace0 \uc9c0\uc6d0\ud558\uace0\uc790 \ud558\ub294 \ub1cc\uc758 \uc815\uad50\ud55c \uc2e0\uacbd \uacbd\ub85c\uc758 \ucd94\uc0c1\uc801\uc778 \ud45c\ud604.<\/figcaption><\/figure>\n<\/div>\n\n\n

\uc774\uc804\uc5d0\ub294 \uc774\ub984\uc744 \ub4e3\ub294 \uc21c\uac04 \ubc14\ub85c \uae30\uc5b5\ud558\uace4 \ud588\uc2b5\ub2c8\ub2e4. \uc774\uc81c\ub294 \uacf5\ubc31\uc774 \uc0dd\uacbc\uc2b5\ub2c8\ub2e4. \uc608\uc804\ub9cc\ud07c \ube68\ub9ac \ub5a0\uc624\ub974\uc9c0 \uc54a\ub294 \ubb34\uc5b8\uac00\ub97c \ucc3e\uc73c\ub824\ub294 \uc2dc\ub3c4\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

\ub2e4 \uc678\uc6e0\ub2e4\uace0 \ud655\uc2e0\ud588\ub358 \uc2dd\ub8cc\ud488 \ubaa9\ub85d\uc774 \uac00\uac8c\uc5d0 \ub3c4\ucc29\ud560 \ub54c\ucbe4\uc774\uba74 \uba38\ub9bf\uc18d\uc5d0\uc11c \uc0ac\ub77c\uc9d1\ub2c8\ub2e4. \uc9c0\ub09c\uc8fc\uc5d0 \uc608\uc57d\ud55c \ud68c\uc758\uac00 \ub2ec\ub825\uc5d0 \ub098\ud0c0\ub098\uc9c0\ub9cc \uc77c\uc815\uc744 \uc7a1\uc740 \uae30\uc5b5\uc774 \uc804\ud600 \uc5c6\uc2b5\ub2c8\ub2e4. \ub9d0\uc744 \ud558\ub358 \ub3c4\uc911, \uc608\uc804\uc5d0\ub294 \ub178\ub825\ud558\uc9c0 \uc54a\uc544\ub3c4 \ub5a0\uc624\ub974\ub358 \ub2e8\uc5b4\ub97c \uae30\ub2e4\ub9ac\uace0 \uc788\ub294 \uc790\uc2e0\uc744 \ubc1c\uacac\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

\uc774\ub7ec\ud55c \uc21c\uac04\ub4e4\uc740 \ucc98\uc74c\uc5d0\ub294 \uac00\ub054\uc529 \uc77c\uc5b4\ub0ac\uc744\uc9c0\ub3c4 \ubaa8\ub985\ub2c8\ub2e4. \ub9cc\uc57d \uc774 \uae00\uc744 \uc77d\uace0 \uacc4\uc2e0\ub2e4\uba74, \uc544\ub9c8\ub3c4 \ub354 \uc774\uc0c1 \uac00\ub054 \uc77c\uc5b4\ub098\ub294 \uc77c\ucc98\ub7fc \ub290\uaef4\uc9c0\uc9c0 \uc54a\uc73c\uc2e4 \uac81\ub2c8\ub2e4.<\/p>\n\n\n\n

\uc758\uc0ac\ub85c\ubd80\ud130 \uacbd\ub3c4\uc778\uc9c0\uc7a5\uc560(Mild Cognitive Impairment, MCI) \uc9c4\ub2e8\uc744 \ubc1b\uc558\ub2e4\uba74, \uc784\uc0c1\uc801 \uc9c0\uce68\uc774 \uac70\uc758 \uc5c6\ub294 \uc9c4\ub2e8\uc744 \uc548\uace0 \uc0b4\uc544\uac00\uace0 \uc788\ub294 \uac83\uc785\ub2c8\ub2e4. \uc6b4\ub3d9\uc744 \ub354 \ub9ce\uc774 \ud558\uace0, \uc798 \uba39\uace0, \ub450\ub1cc\ub97c \ud65c\ubc1c\ud558\uac8c \uc720\uc9c0\ud558\uba70, 1\ub144 \ud6c4\uc5d0 \ub2e4\uc2dc \uc624\ub77c\ub294 \ub9d0\uc744 \ub4e4\uc5c8\uc744 \uac00\ub2a5\uc131\uc774 \ud07d\ub2c8\ub2e4. \ub4e3\uc9c0 \ubabb\ud55c \uac83\uc740 \ubaa8\ub2c8\ud130\ub9c1\uc744 \ub118\uc5b4 \ub1cc \ub0b4\ubd80\uc5d0\uc11c \uc77c\uc5b4\ub098\ub294 \uc77c\uc744 \ub2a6\ucd94\uae30 \uc704\ud574 \uc758\ud559\uc774 \uc2e4\uc81c\ub85c \ubb34\uc5c7\uc744 \ud560 \uc218 \uc788\ub294\uc9c0\uc5d0 \ub300\ud55c \uac83\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

\uc138\uacc4\uc9c8\ubcd1\ubd80\ub2f4\uc5f0\uad6c(Global Burden of Disease study)\uc5d0 \ub530\ub974\uba74 2019\ub144 \uae30\uc900 \uc804 \uc138\uacc4\uc801\uc73c\ub85c \uc57d 6,880\ub9cc \uba85\uc774 \uacbd\ub3c4\uc778\uc9c0\uc7a5\uc560\ub97c \uc553\uace0 \uc788\ub294 \uac83\uc73c\ub85c \ucd94\uc0b0\ub429\ub2c8\ub2e4. \uc774 \uc911 \uc57d 10~15%\uac00 \ub9e4\ub144 \uce58\ub9e4\ub85c \uc9c4\ud589\ub429\ub2c8\ub2e4. \uae30\uc5b5\ub825 \uc800\ud558\uc5d0 \ucd08\uc810\uc744 \ub9de\ucd98 \uc544\ud615\uc778 \uae30\uc5b5\uc0c1\uc2e4\ud615 \uacbd\ub3c4\uc778\uc9c0\uc7a5\uc560(Amnestic MCI)\ub97c \uc553\uace0 \uc788\ub294 \uc0ac\ub78c\ub4e4 \uc911 \uc57d \uc808\ubc18\uc740 \uc9c8\ubcd1\uc758 \uada4\uc801\uc744 \ubc14\uafc0 \uc544\ubb34 \uc870\uce58\ub3c4 \ucde8\ud558\uc9c0 \uc54a\uc744 \uacbd\uc6b0 5\ub144 \uc774\ub0b4\uc5d0 \uc54c\uce20\ud558\uc774\uba38\ubcd1(Alzheimer’s disease)\uc73c\ub85c \ubc1c\uc804\ud560 \uac83\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

\uacbd\ub3c4\uc778\uc9c0\uc7a5\uc560\uc5d0 \ub300\ud55c \uc904\uae30\uc138\ud3ec \uce58\ub8cc\ub294 \ud65c\ubc1c\ud55c \uc784\uc0c1 \uc5f0\uad6c \ubd84\uc57c\uc785\ub2c8\ub2e4. \uc774\uac83\uc740 \uce58\ub8cc\uc81c\uac00 \uc544\ub2c8\uba70, \uc800\ud76c\ub294 \ub2ec\ub9ac \uc2dc\uc0ac\ud558\uc9c0 \uc54a\uc744 \uac83\uc785\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc774\uac83\uc740 \uc0dd\ubb3c\ud559\uc801\uc73c\ub85c \uc77c\uad00\ub41c \uc811\uadfc\ubc95\uc774\uba70 \uc810\uc810 \ub354 \ub9ce\uc740 \ub3d9\ub8cc \ud3c9\uac00 \uc99d\uac70\uac00 \ub4b7\ubc1b\uce68\ud558\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uadf8\ub9ac\uace0 \ub300\ubd80\ubd84\uc758 MCI \ud658\uc790\ub4e4\uc740 \uc758\ud559\uc801 \ub300\ub2f5\uc774 ‘\uc544\ub2c8\uc624’\uc77c \ub54c \uc194\uc9c1\ud558\uac8c \ub9d0\ud574\uc8fc\ub294 \uc784\uc0c1 \ud300\uc73c\ub85c\ubd80\ud130 \ud2b9\uc815 \uc218\uce58\ub97c \ub4e4\uc5b4 \uc194\uc9c1\ud558\uac8c \ub17c\uc758\ub418\ub294 \uac83\uc744 \ub4e4\uc5b4\ubcf8 \uc801\uc774 \uc5c6\uc744 \uac83\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

\uc800\ud76c \ubcf8\uc0ac\ub294 \ub9d0\ub808\uc774\uc2dc\uc544\uc5d0 \uc788\uc2b5\ub2c8\ub2e4. \uc800\ud76c \ud300\uc740 7\ub144 \uc774\uc0c1 \uc7ac\uc0dd \uc758\ud559 \ubd84\uc57c\uc5d0\uc11c \uc77c\ud574 \uc654\uc73c\uba70, \ub2e4\uc591\ud55c \uc9c8\ud658\uc5d0 \uac78\uccd0 \ub3d9\uc885(\uacf5\uc5ec\uc790 \uc720\ub798) \uc81c\ub300 \uc911\uac04\uc5fd \uc904\uae30\uc138\ud3ec(Mesenchymal Stem Cells, MSCs)\ub97c \uc0ac\uc6a9\ud558\uc5ec 200\uba85 \uc774\uc0c1\uc758 \ud658\uc790\ub97c \uce58\ub8cc\ud588\uc2b5\ub2c8\ub2e4. \uc774 \uae00\uc740 \uc784\uc0c1 \uc99d\uac70\uac00 \ubcf4\uc5ec\uc8fc\ub294 \uac83, \ubcf4\uc5ec\uc8fc\uc9c0 \uc54a\ub294 \uac83, \uadf8\ub9ac\uace0 \uc774 \uc811\uadfc\ubc95\uc5d0 \ub300\ud574 \ud604\uc2e4\uc801\uc73c\ub85c \uc801\ud569\ud55c \ud6c4\ubcf4\uc640 \uadf8\ub807\uc9c0 \uc54a\uc740 \ud6c4\ubcf4\uac00 \ub204\uad6c\uc778\uc9c0\ub97c \uc81c\uc2dc\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

<\/div>\n\n\n\n

\ubaa9\ucc28<\/mark><\/h2>\n\n\n
  1. \uacbd\ub3c4\uc778\uc9c0\uc7a5\uc560 \uc9c4\ud589 \uc911 \ub1cc \ub0b4\ubd80\uc5d0\uc11c \uc77c\uc5b4\ub098\ub294 \uc77c<\/a>
      <\/ol><\/li>
    1. \uacbd\ub3c4\uc778\uc9c0\uc7a5\uc560\uc5d0 \ub300\ud55c \ud45c\uc900 \uce58\ub8cc\uc758 \ud55c\uacc4<\/a>
        <\/ol><\/li>
      1. \uc784\uc0c1 \uc99d\uac70\uac00 MCI \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc5d0 \ub300\ud574 \ubcf4\uc5ec\uc8fc\ub294 \uac83<\/a>
          <\/ol><\/li>
        1. \uc904\uae30\uc138\ud3ec\uac00 \uacbd\ub3c4\uc778\uc9c0\uc7a5\uc560\uc758 \uc0dd\ubb3c\ud559\uc801 \uc6d0\uc778\uc744 \ub2e4\ub8e8\ub294 \ubc29\ubc95<\/a>
            <\/ol><\/li>
          1. \ub204\uac00 MCI \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc758 \uc88b\uc740 \ud6c4\ubcf4\uc774\uba70, \ub204\uac00 \uc544\ub2cc\uac00<\/a>
              <\/ol><\/li>
            1. \ub9d0\ub808\uc774\uc2dc\uc544\uc5d0\uc11c\uc758 MCI \uc904\uae30\uc138\ud3ec \uce58\ub8cc \ud658\uc790 \uacbd\ud5d8<\/a>
                <\/ol><\/li>
              1. \uacbd\ub3c4\uc778\uc9c0\uc7a5\uc560\uc5d0 \ub300\ud55c \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc758 \uc194\uc9c1\ud55c \uc704\ud5d8\uacfc \ud55c\uacc4<\/a>
                  <\/ol><\/li>
                1. \uacbd\ub3c4\uc778\uc9c0\uc7a5\uc560 \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc5d0 \ub300\ud55c FAQ<\/a><\/li>
                2. \uacbd\ubbf8\ud55c \uc778\uc9c0 \uc7a5\uc560\uac00 \uc788\ub294 \uacbd\uc6b0 \ub2e4\uc74c \ub2e8\uacc4\ub85c \ub098\uc544\uac00\uae30<\/a><\/li>
                3. \ucc38\uace0 \uc790\ub8cc<\/a><\/li><\/ol><\/div>\n\n\n
                  <\/div>\n\n\n\n

                  \uacbd\ub3c4\uc778\uc9c0\uc7a5\uc560 \uc9c4\ud589 \uc911 \ub1cc \ub0b4\ubd80\uc5d0\uc11c \uc77c\uc5b4\ub098\ub294 \uc77c<\/mark><\/h2>\n\n\n\n

                  MCI\uc5d0\uc11c \uae30\uc5b5 \uc0c1\uc2e4\uc758 \uc0dd\ubb3c\ud559<\/h3>\n\n\n\n

                  \ub1cc\uc5d0\ub294 \uc57d 860\uc5b5 \uac1c\uc758 \uc2e0\uacbd\uc6d0\uc774 \uc788\uc73c\uba70, \uc774 \uc2e0\uacbd \uc138\ud3ec\ub4e4\uc740 \ubc29\ub300\ud55c \uc804\uae30\ud654\ud559\uc801 \uc2e0\ud638 \ub124\ud2b8\uc6cc\ud06c\ub97c \ud1b5\ud574 \uc758\uc0ac\uc18c\ud1b5\ud569\ub2c8\ub2e4. \uc774 \uc2e0\uacbd\uc6d0\ub4e4\uc740 \uc2dc\ub0c5\uc2a4\ub77c\ub294 \uc811\ud569\ubd80\uc5d0\uc11c \uc5f0\uacb0\ub418\uba70, \ud55c \uc138\ud3ec\uac00 \ud654\ud559\uc801 \uba54\uc2e0\uc800(\uc2e0\uacbd\uc804\ub2ec\ubb3c\uc9c8)\ub97c \ubc29\ucd9c\ud558\uc5ec \ubbf8\uc138\ud55c \ud2c8\uc744 \uac74\ub108 \ub2e4\uc74c \uc138\ud3ec\ub97c \ud65c\uc131\ud654\ud569\ub2c8\ub2e4. \uc774\uac83\uc774 \uae30\uc5b5\uc774 \ud615\uc131\ub418\uace0, \uc800\uc7a5\ub418\uba70, \uac80\uc0c9\ub418\ub294 \ubc29\uc2dd\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uacbd\ub3c4\uc778\uc9c0\uc7a5\uc560\uc5d0\uc11c \uc774 \uacfc\uc815\uc740 \ud2b9\uc815 \uc601\uc5ed\uc5d0\uc11c \ubd95\uad34\ub418\uae30 \uc2dc\uc791\ud569\ub2c8\ub2e4. \uc0c8\ub85c\uc6b4 \uae30\uc5b5\uc744 \ud615\uc131\ud558\ub294 \ub1cc\uc758 \uc8fc\uc694 \uad6c\uc870\uc778 \ud574\ub9c8\uac00 \uc77c\ubc18\uc801\uc73c\ub85c \uac00\uc7a5 \uba3c\uc800 \uc601\ud5a5\uc744 \ubc1b\ub294 \uc601\uc5ed\uc785\ub2c8\ub2e4. \ud574\ub9c8\uc640 \uadf8 \uc8fc\ubcc0\uc758 \uc2e0\uacbd\uc6d0\uc740 \uc644\uc804\ud55c \uce58\ub9e4\uac00 \ubc1c\uc0dd\ud558\uae30 \ud6e8\uc52c \uc804\uc5d0 \uc5f0\uacb0\uc744 \uc783\uace0, \uc218\ucd95\ud558\uba70, \uc5b4\ub5a4 \uacbd\uc6b0\uc5d0\ub294 \uc8fd\uae30 \uc2dc\uc791\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc774 \ubd95\uad34\uc758 \uc911\uc2ec\uc5d0\ub294 \ub450 \uac00\uc9c0 \uacfc\uc815\uc774 \uc788\uc73c\uba70, \ub458 \ub2e4 \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uac00 \uc791\ub3d9\ud558\ub3c4\ub85d \uc124\uacc4\ub41c \ubc29\uc2dd\uacfc \uc0dd\ubb3c\ud559\uc801\uc73c\ub85c \uc5f0\uad00\ub418\uc5b4 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uccab \ubc88\uc9f8\ub294 \ub1cc \ub0b4\ubd80\uc758 \ub9cc\uc131 \uc5fc\uc99d\uc778 \uc2e0\uacbd\uc5fc\uc99d(Neuroinflammation)\uc785\ub2c8\ub2e4. \ub1cc\uc5d0\ub294 \uac10\uc5fc\uc73c\ub85c\ubd80\ud130 \uc2e0\uacbd\uc6d0\uc744 \ubcf4\ud638\ud558\uace0 \uc138\ud3ec \uc794\ud574\ub97c \uc81c\uac70\ud558\ub294 \uc815\uc0c1\uc801\uc778 \uc5ed\ud560\uc744 \ud558\ub294 \ubbf8\uc138\uc544\uad50\uc138\ud3ec(Microglia)\ub77c\ub294 \uc790\uccb4 \uba74\uc5ed \uc138\ud3ec\uac00 \uc788\uc2b5\ub2c8\ub2e4. MCI\uc5d0\uc11c \uc774 \ubbf8\uc138\uc544\uad50\uc138\ud3ec\ub294 \ubcf4\ud638\ud558\ub294 \uc5ed\ud560\uc5d0\uc11c \ud30c\uad34\uc801\uc778 \uc5ed\ud560\ub85c \uc804\ud658\ub418\uc5b4 \ubcf4\ud638\ud574\uc57c \ud560 \uc2e0\uacbd\uc6d0 \uc790\uccb4\ub97c \uc190\uc0c1\uc2dc\ud0a4\ub294 \uc5fc\uc99d \ubd84\uc790\ub97c \ubc29\ucd9c\ud569\ub2c8\ub2e4. \uc774\uac83\uc740 \ub2e8\uae30\uc801\uc778 \uba74\uc5ed \ubc18\uc751\uc774 \uc544\ub2d9\ub2c8\ub2e4. \uc778\uc9c0 \uae30\ub2a5 \uc800\ud558\ub97c \ucd09\uc9c4\ud558\ub294 \uc9c0\uc18d\uc801\uc774\uace0 \ub0ae\uc740 \uc218\uc900\uc758 \ud654\uc7ac\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \ub450 \ubc88\uc9f8\ub294 \uc2e0\uacbd\uc601\uc591 \uc9c0\uc6d0\uc758 \uc190\uc2e4\uc785\ub2c8\ub2e4. \uc2e0\uacbd\uc6d0\uc740 \ubd80\ubd84\uc801\uc73c\ub85c \uc2e0\uacbd\uc601\uc591\uc778\uc790\ub77c\ub294 \ub2e8\ubc31\uc9c8\uc758 \uc791\uc6a9\uc744 \ud1b5\ud574 \uac74\uac15\uc744 \uc720\uc9c0\ud569\ub2c8\ub2e4. \uc774 \uc911 \uac00\uc7a5 \uc911\uc694\ud55c \uac83\uc740 \ub1cc\uc720\ub798 \uc2e0\uacbd\uc601\uc591\uc778\uc790(Brain-Derived Neurotrophic Factor, BDNF)\ub85c, \ub1cc \uc138\ud3ec\uc758 \ube44\ub8cc\ub77c\uace0 \uc0dd\uac01\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4. BDNF\ub294 \uc2e0\uacbd\uc6d0 \uc0dd\uc874\uc744 \uc9c0\uc6d0\ud558\uace0, \uc2dc\ub0c5\uc2a4 \uc5f0\uacb0\uc758 \uc720\uc9c0\ub97c \uc7a5\ub824\ud558\uba70, \uae30\uc5b5\uc774 \uc758\uc874\ud558\ub294 \uc778\uc9c0\uc801 \uc720\uc5f0\uc131\uc744 \ubcf4\uc874\ud569\ub2c8\ub2e4. MCI\uc758 \uacbd\uc6b0 \ud574\ub9c8 \ubc0f \uc8fc\ubcc0 \uc601\uc5ed\uc758 BDNF \uc218\uce58\uac00 \uac19\uc740 \uc5f0\ub839\uc758 \uc778\uc9c0\uc801\uc73c\ub85c \uc815\uc0c1\uc778 \uc131\uc778\ubcf4\ub2e4 \uc9c0\uc18d\uc801\uc73c\ub85c \ub0ae\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc2e0\uacbd\uc5fc\uc99d\uacfc \uc2e0\uacbd\uc601\uc591 \uacb0\ud54d\uc774\ub77c\ub294 \uc774 \ub450 \uac00\uc9c0 \uacfc\uc815\uc774 \uc815\ud655\ud788 MSCs \uce58\ub8cc\uac00 \ub2e4\ub8e8\ub3c4\ub85d \uc124\uacc4\ub41c \ud45c\uc801\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                  <\/div>\n\n\n\n

                  MCI \ub1cc\uac00 \uc2a4\uc2a4\ub85c \ubcf5\uad6c\ud560 \uc218 \uc5c6\ub294 \uc774\uc720<\/h3>\n\n\n\n

                  \uc190\uc0c1 \ud6c4 \uc0c1\ub2f9 \ubd80\ubd84\uc744 \uc7ac\uc0dd\ud560 \uc218 \uc788\ub294 \uac04\uc774\ub098 \uba70\uce60 \ub0b4\uc5d0 \ub208\uc5d0 \ub744\ub294 \uc0c1\ucc98\ub97c \uce58\uc720\ud558\ub294 \ud53c\ubd80\uc640 \ub2ec\ub9ac, \uc131\uc778\uc758 \ub1cc\ub294 \uc190\uc2e4\ub41c \uc2e0\uacbd\uc6d0\uc744 \uad50\uccb4\ud560 \ub2a5\ub825\uc774 \uac70\uc758 \uc5c6\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc774\uac83\uc774 MCI\uc758 \ud575\uc2ec \uc0dd\ubb3c\ud559\uc801 \ud604\uc2e4\uc785\ub2c8\ub2e4. \uc774\ubbf8 \uc8fd\uc740 \uc2e0\uacbd\uc6d0\uc740 \ub3cc\uc544\uc624\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \uc808\ub2e8\ub41c \uc5f0\uacb0\uc740 \uc790\ubc1c\uc801\uc73c\ub85c \ub2e4\uc2dc \ud615\uc131\ub418\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc62c\ubc14\ub978 \uc0dd\ubb3c\ud559\uc801 \uc9c0\uc6d0\uc744 \ud1b5\ud574 \ub1cc\uac00 \ud560 \uc218 \uc788\ub294 \uc77c\uc740 \ub0a8\uc544 \uc788\ub294 \uc2e0\uacbd\uc6d0\uc744 \ubcf4\ud638\ud558\uace0, \uc5ec\uc804\ud788 \uc628\uc804\ud55c \uc5f0\uacb0\uc744 \uc720\uc9c0\ud558\uba70, \ucd94\uac00 \uc190\uc0c1\uc774 \ucd95\uc801\ub418\ub294 \uc18d\ub3c4\ub97c \ub2a6\ucd94\ub294 \uac83\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc774 \uc81c\ud55c\uc801\uc774\uc9c0\ub9cc \uc2e4\uc81c\uc801\uc778 \uae30\ud68c\uc758 \ucc3d\uc740 MCI\ub97c \ud655\ub9bd\ub41c \ub9d0\uae30 \uce58\ub9e4\ubcf4\ub2e4 \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc5d0 \uc788\uc5b4 \ub354 \uc720\ub9dd\ud55c \ud45c\uc801\uc73c\ub85c \ub9cc\ub4ed\ub2c8\ub2e4. \uc911\uc99d \uc54c\uce20\ud558\uc774\uba38\ubcd1\uc758 \uacbd\uc6b0 \uad6c\uc870\uc801 \uc190\uc0c1\uc774 \ub108\ubb34 \uad11\ubc94\uc704\ud558\uc5ec \uac1c\uc785\uc744 \uc704\ud55c \uc0dd\ubb3c\ud559\uc801 \ud658\uacbd\uc774 \uc2ec\uac01\ud558\uac8c \uc81c\ud55c\ub429\ub2c8\ub2e4. MCI\uc5d0\ub294 \uc5ec\uc804\ud788 \uc0c1\ub2f9\ud55c \uc591\uc758 \uc0dd\uc874 \uac00\ub2a5\ud55c \uc2e0\uacbd \uc870\uc9c1\uc774 \uc788\uc2b5\ub2c8\ub2e4. \uc784\uc0c1\uc801 \uc9c8\ubb38\uc740 \ub354 \uc190\uc2e4\ub418\uae30 \uc804\uc5d0 \ud574\ub2f9 \uc870\uc9c1\uc744 \uc9c0\uc6d0\ud558\uace0 \ubcf4\ud638\ud560 \uc218 \uc788\ub294\uc9c0 \uc5ec\ubd80\uc640 \uadf8\ub807\uac8c \ud558\ub294 \uac83\uc774 \ud574\ub2f9 \ub1cc \uc548\uc5d0 \uc0b4\uace0 \uc788\ub294 \uc0ac\ub78c\uc5d0\uac8c \uc758\ubbf8 \uc788\ub294 \ucc28\uc774\ub97c \ub9cc\ub4dc\ub294\uc9c0 \uc5ec\ubd80\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                  <\/div>\n\n\n\n

                  \uacbd\ub3c4\uc778\uc9c0\uc7a5\uc560\uc5d0 \ub300\ud55c \ud45c\uc900 \uce58\ub8cc\uc758 \ud55c\uacc4<\/mark><\/h2>\n\n\n\n

                  MCI\uc5d0 \ub300\ud55c \uc804\ud1b5\uc801 \uce58\ub8cc\uac00 \ud560 \uc218 \uc788\ub294 \uac83\uacfc \ud560 \uc218 \uc5c6\ub294 \uac83<\/h3>\n\n\n\n

                  \ud604\uc7ac \uacbd\ub3c4\uc778\uc9c0\uc7a5\uc560\uc5d0 \ub300\ud574 \uc2b9\uc778\ub41c \uc57d\ub9ac\ud559\uc801 \uce58\ub8cc\ubc95\uc740 \uc5c6\uc2b5\ub2c8\ub2e4. \uc774\uac83\uc740 \uc758\ud559\uc774 \uac04\uacfc\ud55c \uacf5\ubc31\uc774 \uc544\ub2c8\uba70, \uc218\ub9ce\uc740 \ub300\uaddc\ubaa8 \uc784\uc0c1 \uc2dc\ud5d8\uc758 \uacb0\uacfc\ub97c \ubc18\uc601\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc54c\uce20\ud558\uc774\uba38\ubcd1\uc5d0 \uc2b9\uc778\ub41c \uc57d\ubb3c\ub4e4, \uc989 \uc2e0\uacbd\uc804\ub2ec\ubb3c\uc9c8 \uc544\uc138\ud2f8\ucf5c\ub9b0\uc758 \uac00\uc6a9\uc131\uc744 \uc99d\uac00\uc2dc\ud0a4\ub294 \ucf5c\ub9b0\uc5d0\uc2a4\ud14c\ub77c\uc81c \uc5b5\uc81c\uc81c(Cholinesterase inhibitors)\uc778 \ub3c4\ub124\ud398\uc9c8(Donepezil)\uacfc \ub9ac\ubc14\uc2a4\ud2f0\uadf8\ubbfc(Rivastigmine), \uadf8\ub9ac\uace0 \ub2e4\ub978 \uc2e0\ud638 \uc804\ub2ec \uacbd\ub85c\ub97c \uc870\uc808\ud558\ub294 \uba54\ub9cc\ud2f4(Memantine)\uc740 MCI \uc9d1\ub2e8\uc5d0\uc11c \uc5f0\uad6c\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc774\ub4e4 \uc911 \uc5b4\ub290 \uac83\ub3c4 MCI \ub2e8\uacc4\uc758 \uc0ac\ub78c\ub4e4\uc5d0\uac8c\uc11c \uce58\ub9e4\ub85c \uc9c4\ud589\ub420 \uc704\ud5d8\uc744 \uc758\ubbf8 \uc788\uac8c \uac10\uc18c\uc2dc\ud0a4\uac70\ub098 \uc778\uc9c0 \uc810\uc218\uc758 \uc9c0\uc18d\uc801\uc778 \uac1c\uc120\uc744 \uc785\uc99d\ud558\uc9c0 \ubabb\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \ub530\ub77c\uc11c \ub300\ubd80\ubd84\uc758 \uc2e0\uacbd\uacfc \uc804\ubb38\uc758\uc640 \ub178\uc778\ubcd1 \uc804\ubb38\uc758\uac00 \ub530\ub974\ub294 \uc9c0\uce68\uc5d0\uc11c\ub294 \uc2ec\ud608\uad00 \uc704\ud5d8 \uc694\uc778(\ud608\uc555, \ucf5c\ub808\uc2a4\ud14c\ub864, \ud608\ub2f9) \uad00\ub9ac, \uc8fc\ub2f9 150\ubd84 \uc774\uc0c1\uc758 \uc720\uc0b0\uc18c \uc6b4\ub3d9, \uc778\uc9c0\uc801 \ucc38\uc5ec \ubc0f \uc815\uc2e0\uc801 \uc790\uadf9, \ucda9\ubd84\ud55c \uc218\uba74, \uc815\uae30\uc801\uc778 \ubaa8\ub2c8\ud130\ub9c1(\uc77c\ubc18\uc801\uc73c\ub85c \ub9e4\ub144 \ub610\ub294 \ubc18\ub144\ub9c8\ub2e4 \uc2e4\uc2dc\ud558\ub294 \uc2e0\uacbd\uc2ec\ub9ac\ud559\uc801 \ud3c9\uac00)\uc744 \uad8c\uc7a5\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc774\ub7ec\ud55c \uad8c\uc7a5 \uc0ac\ud56d\uc740 \uc9c4\uc815\uc73c\ub85c \uc99d\uac70\uc5d0 \uae30\ubc18\uc744 \ub450\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uc2ec\ud608\uad00 \uac74\uac15\uc740 \ub1cc \uac74\uac15\uacfc \ubc00\uc811\ud558\uac8c \uc5f0\uad00\ub418\uc5b4 \uc788\uc73c\uba70, \ub9cc\uc131 \ud608\uad00 \uc9c8\ud658\uc740 \uc778\uc9c0 \uae30\ub2a5 \uc800\ud558\uc5d0 \uc788\uc5b4 \uac00\uc7a5 \uac15\ub825\ud55c \uc218\uc815 \uac00\ub2a5\ud55c \uc704\ud5d8 \uc694\uc778 \uc911 \ud558\ub098\uc785\ub2c8\ub2e4. \uc5ec\ub7ec \ubb34\uc791\uc704 \uc2dc\ud5d8\uc5d0\uc11c \uc720\uc0b0\uc18c \uc6b4\ub3d9\uc740 \uc704\ud5d8 \uc9d1\ub2e8\uc5d0\uc11c \ud574\ub9c8 \ubd80\ud53c\ub97c \uc99d\uac00\uc2dc\ud0a4\uace0 \uc778\uc9c0 \uae30\ub2a5 \uc800\ud558\ub97c \ub2a6\ucd94\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uc800\ud76c\ub294 \uc774\ub7ec\ud55c \uc0dd\ud65c \uc2b5\uad00 \uc694\uc778\ub4e4\uc744 \uacb0\ucf54 \uac00\ubccd\uac8c \uc5ec\uae30\uc9c0 \uc54a\uc73c\uba70, \uc774\ub97c \ucd94\uac00\uc801\uc778 \uac1c\uc785\uc744 \uc704\ud55c \ud544\uc218\uc801\uc778 \uae30\ucd08\ub85c \uac04\uc8fc\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc774 \uc811\uadfc\ubc95\uc758 \ud55c\uacc4\ub294 \uad6c\uc870\uc801\uc785\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uad8c\uc7a5 \uc0ac\ud56d\uc740 \uc704\ud5d8\uc744 \uad00\ub9ac\ud569\ub2c8\ub2e4. \uc774\ub4e4\uc740 \uc9c8\ud658\uc744 \uc2e4\uc2dc\uac04\uc73c\ub85c \uc9c4\ud589\uc2dc\ud0a4\ub294 \ud65c\ubc1c\ud55c \uc0dd\ubb3c\ud559\uc801 \uacfc\uc815(\uc2e0\uacbd\uc5fc\uc99d, \uc2dc\ub0c5\uc2a4 \uc545\ud654, \uc2e0\uacbd\uc601\uc591 \uc800\ud558)\uc744 \ub2e4\ub8e8\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \uc0dd\ud65c \uc2b5\uad00 \ucd5c\uc801\ud654\uc5d0\ub3c4 \ubd88\uad6c\ud558\uace0 MCI\uac00 \uc9c4\ud589 \uc911\uc778 \ud658\uc790\uc758 \uacbd\uc6b0, \uc0dd\ubb3c\ud559\uc801\uc73c\ub85c \ub354 \uac00\ub2a5\ud55c \uac83\uc774 \ubb34\uc5c7\uc778\uc9c0\uc5d0 \ub300\ud55c \uc9c8\ubb38\uc740 \ud45c\uc900 \uc784\uc0c1 \ubc18\uc751\uc774 \uc778\uc815\ud558\uc9c0 \uc54a\ub294 \ubc29\uc2dd\uc73c\ub85c \uc2dc\uae09\ud574\uc9d1\ub2c8\ub2e4..<\/p>\n\n\n\n

                  <\/div>\n\n\n\n

                  \uc65c “\uc9c0\ucf1c\ubcf4\uace0 \uae30\ub2e4\ub9ac\ub294 \uac83”\uc774 \ub9ce\uc740 MCI \ud658\uc790\ub4e4\uc5d0\uac8c \ubd88\ucda9\ubd84\ud558\uac8c \ub290\uaef4\uc9c0\ub294\uac00<\/h3>\n\n\n\n

                  “\ubaa8\ub2c8\ud130\ub9c1\ud558\uace0 1\ub144 \ud6c4\uc5d0 \ub2e4\uc2dc \uc624\uc138\uc694”\ub77c\ub294 \uc870\uc5b8\uc740 \uc784\uc0c1\uc801\uc73c\ub85c\ub294 \ubc29\uc5b4 \uac00\ub2a5\ud558\uc9c0\ub9cc, \ud2b9\uc815 \ubc29\uc2dd\uc5d0\uc11c\ub294 \uac10\uc815\uc801\uc73c\ub85c \uc5b4\ub835\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \ub300\ubd80\ubd84\uc758 \ud658\uc790\uc5d0\uac8c MCI\ub294 \ubc29\ud5a5\uc131\uc744 \uac16\uc2b5\ub2c8\ub2e4. \uac19\uc740 \uc0c1\ud0dc\ub85c \uba38\ubb3c\ub7ec \uc788\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \ubcc0\ud654\uc758 \uc18d\ub3c4\ub294 \ub2e4\uc591\ud558\uba70 \uc0c1\ub2f9\uc218\uc758 MCI \ud658\uc790\ub294 5\ub144 \uc774\ub0b4\uc5d0 \uce58\ub9e4\ub85c \uc9c4\ud589\ub418\uc9c0 \uc54a\uc9c0\ub9cc, \uc9c4\ud589 \uc911\uc778 \uc0ac\ub78c\ub4e4\uc5d0\uac8c \ub9e4\ub144\uc740 \ud55c \ubc88 \uc783\uc73c\uba74 \ud68c\ubcf5\ud560 \uc218 \uc5c6\ub294 \uc2e4\uc9c8\uc801\uc778 \uc778\uc9c0 \uc601\uc5ed\uc744 \ub098\ud0c0\ub0c5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc810\uc810 \ub354 \ub0b4\ub9ac\uae30 \uc5b4\ub824\uc6cc\uc9c0\ub294 \uacb0\uc815\ub4e4, \ub530\ub77c\uac00\uae30 \ub354 \uc5b4\ub824\uc6cc\uc9c0\ub294 \ub300\ud654\ub4e4, \ub354 \ub9ce\uc740 \ub178\ub825\uc744 \ud544\uc694\ub85c \ud558\uae30 \uc2dc\uc791\ud558\ub294 \ub3c5\ub9bd\uc131, \uc774\ub7ec\ud55c \uac83\ub4e4\uc740 \uadf8\uac83\uc744 \uacbd\ud5d8\ud558\ub294 \uc0ac\ub78c\uacfc \uadf8\ub4e4 \uc8fc\ubcc0 \uc0ac\ub78c\ub4e4\uc5d0\uac8c \uae4a\uc774 \uc911\uc694\ud55c \ubc29\uc2dd\uc73c\ub85c \ucd95\uc801\ub429\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc800\ud76c \ud074\ub9ac\ub2c9\uc5d0 \uc624\ub294 \ud658\uc790\ub4e4\uc740 \uc0dd\ud65c \uc2b5\uad00 \uad00\ub9ac\ub97c \ud3ec\uae30\ud55c \uc0ac\ub78c\ub4e4\uc774 \uc544\ub2d9\ub2c8\ub2e4. \uadf8\ub4e4\uc740 \uc77c\ubc18\uc801\uc73c\ub85c \ud558\ub77c\ub294 \ubaa8\ub4e0 \uac83\uc744 \ub2e4 \ud588\uc74c\uc5d0\ub3c4 \uc790\uc2e0\uc758 \uc778\uc9c0 \ub2a5\ub825\uc774 \uacc4\uc18d \ubcc0\ud558\ub294 \uac83\uc744 \uc9c0\ucf1c\ubcf4\uace0 \uc788\ub294 \uc0ac\ub78c\ub4e4\uc785\ub2c8\ub2e4. \uadf8\ub4e4\uc740 \uc758\ud559\uc774 \uc81c\uacf5\ud560 \uac83\uc774 \ub354 \uc788\ub294\uc9c0, \uad6c\uccb4\uc801\uc73c\ub85c \ub2e8\uc21c\ud788 \uadf8 \uacb0\uacfc\uac00 \uc544\ub2c8\ub77c \uc778\uc9c0 \uae30\ub2a5 \uc800\ud558\uc758 \uc0dd\ubb3c\ud559\uc801 \uba54\ucee4\ub2c8\uc998\uacfc \uad00\ub828\ub41c \ubb34\uc5b8\uac00\uac00 \uc788\ub294\uc9c0 \uc54c\uace0 \uc2f6\uc5b4 \ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

                  <\/div>\n\n\n\n

                  \uc784\uc0c1 \uc99d\uac70\uac00 MCI \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc5d0 \ub300\ud574 \ubcf4\uc5ec\uc8fc\ub294 \uac83<\/mark><\/h2>\n\n\n
                  \n
                  \"\uc911\uac04\uc5fd
                  \ubc1c\ud45c\ub41c \uc784\uc0c1 1\/2a\uc0c1 \uc2dc\ud5d8\uc5d0\uc11c, \uacbd\uc99d \uc54c\uce20\ud558\uc774\uba38 \ubc0f \uae30\uc5b5\uc0c1\uc2e4\ud615 MCI \uc9d1\ub2e8\uc758 MSCs \uce58\ub8cc\ub294 \uc704\uc57d\uad70\uc5d0 \ube44\ud574 \uac04\uc774\uc815\uc2e0\uc0c1\ud0dc\uac80\uc0ac(Mini-Mental State Examination, MMSE) \ubc0f \uc54c\uce20\ud558\uc774\uba38\ubcd1 \ud3c9\uac00 \ucc99\ub3c4 \uc778\uc9c0 \ud558\uc704 \ucc99\ub3c4(Alzheimer’s Disease Assessment Scale Cognitive subscale, ADAS-Cog) \ud558\ub77d\ub960\uc744 \uac10\uc18c\uc2dc\ucf30\uc2b5\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uc774\uc810\uc740 6\uac1c\uc6d4 \ub54c\ubcf4\ub2e4 12~24\uac1c\uc6d4 \ucd94\uc801 \uad00\ucc30\uc5d0\uc11c \ub354 \uba85\ud655\ud588\uc2b5\ub2c8\ub2e4.<\/figcaption><\/figure>\n<\/div>\n\n\n

                  MCI \ubc0f \uc778\uc9c0 \uae30\ub2a5 \uc800\ud558\uc5d0 \ub300\ud55c MSC \uce58\ub8cc\uc758 \uc8fc\uc694 \uc784\uc0c1 \uc5f0\uad6c<\/h3>\n\n\n\n

                  \ub370\uc774\ud130\ub97c \ub2e4\ub8e8\uae30 \uc804 \uc911\uc694\ud55c \ud22c\uba85\uc131 \ud3ec\uc778\ud2b8: \uc778\uac04 \ud53c\ud5d8\uc790\ub97c \ub300\uc0c1\uc73c\ub85c \ud55c MSCs \uce58\ub8cc\uc5d0 \ub300\ud574 \uac00\uc7a5 \uc5c4\uaca9\ud558\uac8c \ubc1c\ud45c\ub41c \uc784\uc0c1 \uc5f0\uad6c\ub294 MCI\uc5d0 \ud2b9\uc815\ub41c \uac83\uc774 \uc544\ub2c8\ub77c \uc8fc\ub85c \uacbd\uc99d\uc5d0\uc11c \uc911\ub4f1\ub3c4\uc758 \uc54c\uce20\ud558\uc774\uba38\ubcd1 \uc9d1\ub2e8\uc744 \ub300\uc0c1\uc73c\ub85c \uc218\ud589\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc774 \uc810\uc740 \uba85\ud655\ud788 \ubc1d\ud790 \uac00\uce58\uac00 \uc788\uc2b5\ub2c8\ub2e4. \uae30\uc5b5\ub825\uc5d0 \ucd08\uc810\uc744 \ub9de\ucd98 \ud558\uc704 \uc720\ud615\uc778 \uae30\uc5b5\uc0c1\uc2e4\ud615 MCI\ub294 \ud604\uc7ac \uc5f0\uad6c\uc790\ub4e4\uc5d0 \uc758\ud574 \uc54c\uce20\ud558\uc774\uba38\ubcd1 \uc5f0\uc18d\uccb4\uc758 \ucd08\uae30 \uc784\uc0c1 \ub2e8\uacc4\ub97c \ub098\ud0c0\ub0b4\ub294 \uac83\uc73c\ub85c \ub110\ub9ac \uc774\ud574\ub418\uace0 \uc788\uc73c\uba70, \uc0dd\ubb3c\ud559\uc801\uc73c\ub85c \ud06c\uac8c \uc911\ucca9\ub429\ub2c8\ub2e4. \uadf8\ub7ec\ub098 \uc9d1\ub2e8\uc774 \ub3d9\uc77c\ud558\uc9c0\ub294 \uc54a\uc73c\uba70, \uc99d\uac70\ub294 \ubaa8\ub4e0 \uacbd\uc6b0\uc5d0 \uc9c1\uc811 \uc801\uc6a9\ub41c\ub2e4\uae30\ubcf4\ub2e4\ub294 \uc678\uc0bd\ub429\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc774\ub7ec\ud55c \ub9e5\ub77d\uc774 \ud655\ub9bd\ub41c \uac00\uc6b4\ub370, \ubc1c\ud45c\ub41c \ub370\uc774\ud130\uac00 \ubcf4\uc5ec\uc8fc\ub294 \ub0b4\uc6a9\uc740 \ub2e4\uc74c\uacfc \uac19\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uac00\uc7a5 \ubc29\ubc95\ub860\uc801\uc73c\ub85c \uc5c4\uaca9\ud558\uac8c \uc644\ub8cc\ub41c \uc2dc\ud5d8 \uc911 \ud558\ub098\ub294 2021\ub144 Alzheimer’s Research and Therapy\uc5d0 \ubc1c\ud45c\ub41c Kwon\uacfc \ub3d9\ub8cc\ub4e4\uc774 \ud55c\uad6d\uc5d0\uc11c \uc218\ud589\ud55c \uc784\uc0c1 1\/2a\uc0c1 \ubb34\uc791\uc704 \ub300\uc870 \uc2dc\ud5d8\uc778 NEUROSTEM \uc5f0\uad6c\uc785\ub2c8\ub2e4. \uc774 \uc2dc\ud5d8\uc740 45\uba85\uc758 \uacbd\uc99d\uc5d0\uc11c \uc911\ub4f1\ub3c4 \uc54c\uce20\ud558\uc774\uba38\ubcd1 \ud658\uc790\ub97c \ub4f1\ub85d\ud558\uc5ec \uc704\uc57d\uad70\uacfc \ube44\uad50\ud558\uc5ec \ub450 \uac00\uc9c0 \uc6a9\ub7c9 \uc218\uc900\uc73c\ub85c \uc81c\ub300\ud608 \uc720\ub798 \uc911\uac04\uc5fd \uc904\uae30\uc138\ud3ec\ub97c \ud22c\uc5ec\ud588\uc2b5\ub2c8\ub2e4. 1\ucc28 \uc548\uc804\uc131 \ud3c9\uac00\ubcc0\uc218\ub294 \ub450 \uc6a9\ub7c9 \uc218\uc900 \ubaa8\ub450\uc5d0\uc11c \ucda9\uc871\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc904\uae30\uc138\ud3ec\uc5d0 \uae30\uc778\ud55c \uc2ec\uac01\ud55c \uc774\uc0c1 \ubc18\uc751\uc740 \uc5c6\uc5c8\uc2b5\ub2c8\ub2e4. \uace0\uc6a9\ub7c9\uad70\uc5d0\uc11c \uc784\uc0c1 \uc2dc\ud5d8\uc5d0\uc11c \ub110\ub9ac \uc0ac\uc6a9\ub418\ub294 \uae30\uc5b5\ub825, \uc5b8\uc5b4 \ubc0f \uc8fc\uc758\ub825\uc5d0 \ub300\ud55c \ud45c\uc900\ud654\ub41c \ud14c\uc2a4\ud2b8\uc778 ADAS-Cog\uc758 \ud558\ub77d\ub960\uc740 24\uac1c\uc6d4\uc9f8\uc5d0 \uc704\uc57d\uad70\ubcf4\ub2e4 \ub208\uc5d0 \ub744\uac8c \ub290\ub838\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc774\uc804 NEUROSTEM \ucf54\ud638\ud2b8\ub97c \uc0ac\uc6a9\ud558\uc5ec 2015\ub144 Journal of Alzheimer’s Disease\uc5d0 \ubc1c\ud45c\ub41c Oh\uc640 \ub3d9\ub8cc\ub4e4\uc758 1\uc0c1 \uc5f0\uad6c\uc5d0\uc11c\ub294 9\uba85\uc758 \uc54c\uce20\ud558\uc774\uba38 \ud658\uc790\ub97c \ub4f1\ub85d\ud558\uc5ec \uc778\uac04 \uc2e0\uacbd \uc904\uae30\uc138\ud3ec\ub97c \ub1cc \ucc99\uc218\uc561 \uacf5\uac04\uc5d0 \uc9c1\uc811 \ubc18\ubcf5\uc801\uc73c\ub85c \uc8fc\uc785\ud588\uc2b5\ub2c8\ub2e4. 24\uac1c\uc6d4 \ub3d9\uc548 9\uba85\uc758 \ud658\uc790 \uc911 4\uba85\uc740 \uce58\ub8cc\ubc1b\uc9c0 \uc54a\uc740 \uc9d1\ub2e8\uc758 \uc608\uc0c1 \uac10\uc18c\uc728\uacfc \ube44\uad50\ud558\uc5ec MMSE(24\uc810 \uc774\uc0c1\uc774\uba74 \uc77c\ubc18\uc801\uc73c\ub85c \uc815\uc0c1 \uc778\uc9c0\ub97c \ub098\ud0c0\ub0b4\ub294 30\uc810 \ucc99\ub3c4)\uc5d0\uc11c \uc548\uc815\ud654 \ub610\ub294 \uc801\ub2f9\ud55c \uac1c\uc120\uc744 \ubcf4\uc600\uc2b5\ub2c8\ub2e4. \uc2ec\uac01\ud55c \uce58\ub8cc \uad00\ub828 \uc774\uc0c1 \ubc18\uc751\uc740 \uae30\ub85d\ub418\uc9c0 \uc54a\uc558\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \ub9d0\ub808\uc774\uc2dc\uc544\uc5d0\uc11c \uc0ac\uc6a9\ub418\uba70 \uc9c1\uc811\uc801\uc778 \ub1cc \ub610\ub294 \ucc99\uc218 \uc8fc\uc0ac\ub97c \ud53c\ud558\ub294 \uc811\uadfc\ubc95\uc778 \uc815\ub9e5 \ud22c\uc5ec \uacbd\ub85c\uc758 \uacbd\uc6b0, 2023\ub144 Frontiers in Aging Neuroscience\uc5d0 \ubc1c\ud45c\ub41c \uc5f0\uad6c\uc5d0\uc11c\ub294 \uacbd\uc99d \uc54c\uce20\ud558\uc774\uba38\ubcd1 \ub610\ub294 \uae30\uc5b5\uc0c1\uc2e4\ud615 MCI \ud658\uc790 40\uba85\uc744 \ub4f1\ub85d\ud558\uc5ec \uc815\ub9e5 \uc81c\ub300 \uc720\ub798 MSCs \uc8fc\uc785\uc744 \uc704\uc57d\uacfc \ube44\uad50\ud588\uc2b5\ub2c8\ub2e4. 12\uac1c\uc6d4\uc9f8\uc5d0 \uce58\ub8cc\uad70\uc740 \ub1cc\ucc99\uc218\uc561\uc758 \uc778\ud130\ub8e8\ud0a8-6(Interleukin-6, \uc2e0\uacbd \ud1f4\ud589\uc5d0\uc11c \uc9c0\uc18d\uc801\uc73c\ub85c \uc0c1\uc2b9\ud558\ub294 \uc5fc\uc99d\uc744 \ucd09\uc9c4\ud558\ub294 \ud654\ud559\uc801 \uba54\uc2e0\uc800) \uc218\uce58 \uac10\uc18c\uc640 \ud568\uaed8 MMSE \ud558\ub77d\ub960\uc758 \ud1b5\uacc4\uc801\uc73c\ub85c \uc720\uc758\ubbf8\ud55c \uac10\uc18c\ub97c \ubcf4\uc600\uc2b5\ub2c8\ub2e4. \uc774 \ud6a8\uacfc\ub294 \uacbd\uc99d \uc54c\uce20\ud558\uc774\uba38 \ud558\uc704 \uc9d1\ub2e8\ubcf4\ub2e4 MCI \ud558\uc704 \uc9d1\ub2e8\uc5d0\uc11c \ub354 \ub450\ub4dc\ub7ec\uc84c\uc73c\uba70, \uc774\ub294 \uc0dd\ubb3c\ud559\uc774 \uc608\uce21\ud558\ub294 \ubc14\uc640 \uc77c\uce58\ud558\ub294 \ubc1c\uacac\uc785\ub2c8\ub2e4. \uc989, \uc190\uc0c1\uc774 \ub35c\ud55c \uc2e0\uacbd \ud658\uacbd\uc5d0\uc11c \ub354 \uc774\ub978 \uac1c\uc785\uc774 \ub354 \uba85\ud655\ud55c \uc774\uc810\uc744 \uc0dd\uc131\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

                  <\/div>\n\n\n\n

                  \uc904\uae30\uc138\ud3ec \uce58\ub8cc \ud6c4 MCI \ud658\uc790\uc758 \ud604\uc2e4\uc801\uc778 \uac1c\uc120 \ubaa8\uc2b5<\/h3>\n\n\n\n

                  \uc6b0\ub9ac\ub294 \uc774\ub7ec\ud55c \uacb0\uacfc\uac00 \uc2e4\uc81c\uc801\uc73c\ub85c \ubb34\uc5c7\uc744 \uc758\ubbf8\ud558\ub294\uc9c0 \uc815\ud655\ud558\uac8c \uc804\ub2ec\ud558\uace0\uc790 \ud569\ub2c8\ub2e4. \ucd5c\uc0c1\uc758 \uacb0\uacfc\ub9cc\uc744 \uc120\ubcc4\uc801\uc73c\ub85c \ubcf4\uace0\ud558\ub294 \uac83\uc740 \ud658\uc790\uc5d0\uac8c \uc9c4\uc815\ud55c \ud574\ub97c \ub07c\uce58\uae30 \ub54c\ubb38\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                  MMSE \uc810\uc218\ub294 \uc77c\ubc18\uc801\uc73c\ub85c \uce58\ub8cc\ubc1b\uc9c0 \uc54a\uc740 \uae30\uc5b5\uc0c1\uc2e4\ud615 MCI \ubc0f \ucd08\uae30 \uc54c\uce20\ud558\uc774\uba38 \uc9d1\ub2e8\uc5d0\uc11c \ub9e4\ub144 \uc57d 2~4\uc810 \ud558\ub77d\ud569\ub2c8\ub2e4. \uac00\uc7a5 \uad00\ub828\uc131\uc774 \ub192\uc740 \ubc1c\ud45c\ub41c \uc2dc\ud5d8 \uc804\ubc18\uc5d0 \uac78\uccd0 \uce58\ub8cc\uad70\uc5d0\uc11c \uadf8 \ud558\ub77d\ub960\uc740 \uac10\uc18c\ud588\uc2b5\ub2c8\ub2e4. \uc77c\ubd80 \uc5f0\uad6c\uc5d0\uc11c\ub294 \uc5f0\uac04 1\uc810 \ubbf8\ub9cc\uc73c\ub85c, \ub2e4\ub978 \uc5f0\uad6c\uc5d0\uc11c\ub294 12~24\uac1c\uc6d4\uc5d0 \uac78\uccd0 \uac70\uc758 \uc548\uc815\ud654\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc774\uac83\uc740 \uc5ed\uc804\uc774 \uc544\ub2d9\ub2c8\ub2e4. \uc9c0\uc5f0\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \ub9ce\uc740 \ud658\uc790\uc5d0\uac8c \uc9c0\uc5f0\uc740 \ubc14\ub85c \uc911\uc694\ud55c \uac83\uc785\ub2c8\ub2e4. \ub9e4\uc77c\uc758 \uc7ac\uc815\uc744 \uad00\ub9ac\ud558\uace0, \ubcf5\uc7a1\ud55c \ub300\ud654\ub97c \ub530\ub77c\uac00\uace0, \uc804\ubb38\uc801\uc73c\ub85c \uacc4\uc18d \uae30\uc5ec\ud558\uba70, \uc9d1\uc5d0\uc11c \ub3c5\ub9bd\uc131\uc744 \uc720\uc9c0\ud560 \uc218 \uc788\ub294 \uc778\uc9c0 \ub2a5\ub825\uc744 \uc720\uc9c0\ud558\ub294 \uac83\uc785\ub2c8\ub2e4. \uc5f0\uac04 3\uc810 \ud558\ub77d\uacfc \uc5f0\uac04 0.5\uc810 \ud558\ub77d\uc758 \ucc28\uc774\ub294 5\ub144 \ub3d9\uc548 \uce21\uc815\ud588\uc744 \ub54c, \uae30\ub2a5\ud558\ub294 \uc77c\uc0c1\uc0dd\ud65c\uacfc \uc2ec\uac01\ud558\uac8c \uc190\uc0c1\ub41c \uc77c\uc0c1\uc0dd\ud65c\uc758 \ucc28\uc774\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \ub3d9\ub8cc \ud3c9\uac00 \uc2dc\ud5d8\uc5d0\uc11c MCI \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uac00 \uc785\uc99d\ud558\uc9c0 \ubabb\ud55c \uac83\uc740 \uce58\ub8cc \uc804\uc5d0 \uc783\uc5b4\ubc84\ub9b0 \uae30\uc5b5\uc758 \ud68c\ubcf5\uc785\ub2c8\ub2e4. \uc774\ubbf8 \uc78a\uc5b4\ubc84\ub9b0 \uac83\uc744 \uae30\uc5b5\ud574 \ub0bc \uac83\uc774\ub77c\ub294 \ube44\ud604\uc2e4\uc801\uc778 \ud2c0\uc744 \uac00\uc9c0\uace0 \uc774 \uacfc\uc815\uc5d0 \ub4e4\uc5b4\uac00\ub294 \ud658\uc790\ub294 \ube44\ud604\uc2e4\uc801\uc778 \uae30\ub300\uce58\ub97c \uac00\uc9c0\uace0 \uc788\ub294 \uac83\uc785\ub2c8\ub2e4. \uc544\uc9c1 \uac00\uc9c0\uace0 \uc788\ub294 \uac83\uc744 \ub354 \ub9ce\uc774 \ubcf4\uc874\ud558\uace0, \uadf8\uac83\uc744 \uacc4\uc18d \uc783\ub294 \uc18d\ub3c4\ub97c \ub2a6\ucd94\uae30\ub97c \ud76c\ub9dd\ud558\uba70 \uce58\ub8cc\ub97c \ubc1b\ub294 \ud658\uc790\ub294 \uc774\uc6a9 \uac00\ub2a5\ud55c \uc99d\uac70\uac00 \ub4b7\ubc1b\uce68\ud558\ub294 \ud604\uc2e4\uc801\uc778 \ud2c0\uc744 \uac00\uc9c0\uace0 \uc811\uadfc\ud558\ub294 \uac83\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc6b0\ub9ac \ud504\ub85c\uadf8\ub7a8\uc5d0\uc11c \uce58\ub8cc\ubc1b\uc740 \uc758\ubbf8 \uc788\ub294 \ube44\uc728\uc758 MCI \ud658\uc790\ub4e4\uc740 \uce21\uc815 \uac00\ub2a5\ud55c \ubcc0\ud654\ub97c \ubcf4\uc774\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \uc774\uc6a9 \uac00\ub2a5\ud55c \uc2dc\ud5d8 \ub370\uc774\ud130\uc640 \uc9c0\ub09c 7\ub144 \ub3d9\uc548\uc758 \uc784\uc0c1 \uacbd\ud5d8\uc744 \ubc14\ud0d5\uc73c\ub85c, \uc6b0\ub9ac\ub294 MSCs \uce58\ub8cc\ub97c \ubc1b\ub294 MCI \ud658\uc790\uc758 \uc57d 30~40%\uac00 12~24\uac1c\uc6d4 \uae30\uac04 \ub3d9\uc548 \uc5b4\ub290 \uc815\ub3c4 \uce21\uc815 \uac00\ub2a5\ud55c \uc548\uc815\ud654 \ub610\ub294 \uac10\uc18c \uc9c0\uc5f0\uc744 \ubcf4\uc778\ub2e4\uace0 \ucd94\uc815\ud569\ub2c8\ub2e4. \ub098\uba38\uc9c0 60~70%\ub294 \uc774\uc810\uc774 \uc81c\ud55c\uc801\uc774\uac70\ub098 \uc2dd\ubcc4\ud560 \uc218 \uc5c6\ub294 \uc218\uc900\uc785\ub2c8\ub2e4. \uc544\uc9c1 \uce58\ub8cc \uc804\uc5d0 \ub204\uac00 \uc5b4\ub5a4 \uadf8\ub8f9\uc5d0 \uc18d\ud560\uc9c0 \uc548\uc815\uc801\uc73c\ub85c \uc608\uce21\ud560 \uc218\ub294 \uc5c6\uc9c0\ub9cc(\uc544\ub798 \ud6c4\ubcf4\uc790 \uae30\uc900\uc774 \uc758\ubbf8 \uc788\ub294 \uc9c0\uce68\uc744 \uc81c\uacf5\ud558\uae34 \ud569\ub2c8\ub2e4), \ubaa8\ub4e0 \uc0c1\ub2f4\uc5d0\uc11c \uc774\uc5d0 \ub300\ud574 \uc194\uc9c1\ud558\uac8c \ub17c\uc758\ud560 \uac83\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                  (\uc774\ud558 \uc0dd\ub7b5\ud558\uc9c0 \uc54a\uace0 \ucca0\uc800\ud788 \ubc88\uc5ed \uc9c4\ud589)<\/p>\n\n\n\n

                  <\/div>\n\n\n\n

                  \uc904\uae30\uc138\ud3ec\uac00 \uacbd\ub3c4\uc778\uc9c0\uc7a5\uc560\uc758 \uc0dd\ubb3c\ud559\uc801 \uc6d0\uc778\uc744 \ub2e4\ub8e8\ub294 \ubc29\ubc95<\/mark><\/h2>\n\n\n
                  \n
                  \"\uacbd\ub3c4
                  \uc911\uac04\uc5fd \uc904\uae30\uc138\ud3ec\ub294 \uacbd\ub3c4\uc778\uc9c0\uc7a5\uc560\uc5d0\uc11c \uc138 \uac00\uc9c0 \uc911\ucca9\ub418\ub294 \uc0dd\ubb3c\ud559\uc801 \uacbd\ub85c\ub97c \ud1b5\ud574 \uc791\uc6a9\ud569\ub2c8\ub2e4. \uacfc\uc789 \ud65c\uc131\ud654\ub41c \uc2e0\uacbd\uc5fc\uc99d \uc9c4\uc815, \uae30\uc874 \uc2e0\uacbd\uc6d0\uc5d0 \ub300\ud55c \uc2e0\uacbd\uc601\uc591 \uc9c0\uc6d0 \ud68c\ubcf5, \uad00\ub958\uac00 \ubd80\uc871\ud55c \ub1cc \uc870\uc9c1\uc5d0 \ub300\ud55c \ud608\uad00 \uacf5\uae09 \uac1c\uc120\uc785\ub2c8\ub2e4.<\/figcaption><\/figure>\n<\/div>\n\n\n

                  MCI\uc5d0\uc11c MSC \uce58\ub8cc\uc758 \uc138 \uac00\uc9c0 \uc0dd\ubb3c\ud559\uc801 \uba54\ucee4\ub2c8\uc998<\/h3>\n\n\n\n

                  \uc774 \ub9e5\ub77d\uc5d0\uc11c MSCs\ub294 \uc190\uc2e4\ub41c \uc2e0\uacbd\uc6d0\uc744 \ub300\uccb4\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \uc904\uae30\uc138\ud3ec\uac00 \uc0c8\ub85c\uc6b4 \uc2e0\uacbd\uc6d0\uc73c\ub85c \ubcc0\ud615\ub418\uc5b4 \ub1cc \uc870\uc9c1\uc744 \uc9c1\uc811 \uc7ac\uc0dd\ud560 \uc218 \uc788\ub2e4\ub294 \uc774\ub860\uc740 \uc9c0\ub09c 20\ub144\uac04\uc758 \uc5f0\uad6c\ub97c \ud1b5\ud574 \uc810\uc9c4\uc801\uc73c\ub85c \uba85\ud655\ud574\uc84c\uc2b5\ub2c8\ub2e4. MSCs\uac00 \uc2e4\ud5d8\uc2e4 \uc870\uac74\uc5d0\uc11c \ub2e4\uc591\ud55c \uc138\ud3ec \uc720\ud615\uc73c\ub85c \ubd84\ud654\ud560 \uc218 \uc788\uc9c0\ub9cc, \uc190\uc0c1\ub41c \uc778\uac04\uc758 \ub1cc \ub0b4\ubd80(in vivo)\uc5d0\uc11c\ub294 \uc758\ubbf8 \uc788\uac8c \ubc1c\uc0dd\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc99d\uac70\uac00 \ub4b7\ubc1b\uce68\ud558\ub294 \uac83\uc740 MCI\ub97c \uc9c4\ud589\uc2dc\ud0a4\ub294 \ubc14\ub85c \uadf8 \uacfc\uc815\ub4e4\uc744 \ub2e4\ub8e8\ub294 \uac04\uc811\uc801\uc774\uc9c0\ub9cc \uc0dd\ubb3c\ud559\uc801\uc73c\ub85c \uc911\uc694\ud55c \uba54\ucee4\ub2c8\uc998 \uc138\ud2b8\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uccab \ubc88\uc9f8 \uba54\ucee4\ub2c8\uc998\uc740 \uc2e0\uacbd\uc5fc\uc99d \uc870\uc808\uc785\ub2c8\ub2e4. \uc815\ub9e5\uc73c\ub85c \ud22c\uc5ec\ub420 \ub54c MSCs\uc758 \uc77c\ubd80\ub294 \ud65c\uc131 \uc5fc\uc99d \ubd80\uc704\ub85c \uc774\ub3d9\ud558\uc5ec(\uc190\uc0c1\ub41c \uc870\uc9c1\uc5d0\uc11c \ubc29\ucd9c\ub41c \ud654\ud559 \uc2e0\ud638\uc5d0 \uc774\ub04c\ub824) \ud56d\uc5fc\uc99d \uc2e0\ud638 \ubd84\uc790\ub97c \ubc29\ucd9c\ud558\uae30 \uc2dc\uc791\ud569\ub2c8\ub2e4. \ub1cc\uc5d0\uc11c \uc774\uac83\uc740 \ud574\ub9c8 \ubc0f \uc8fc\ubcc0 \uc601\uc5ed\uc5d0\uc11c \uc190\uc0c1\uc744 \uc785\ud788\ub294 \uc5fc\uc99d\uc131 \ub2e8\ubc31\uc9c8\uc744 \ubc29\ucd9c\ud558\ub294 \uacfc\uc789 \ud65c\uc131\ud654\ub41c \ubbf8\uc138\uc544\uad50\uc138\ud3ec\uc640 \uacb0\ud569\ud568\uc744 \uc758\ubbf8\ud569\ub2c8\ub2e4. MSCs\ub294 \uba74\uc5ed \uc138\ud3ec \ud589\ub3d9\uc744 \uc870\uc808\ud558\ub294 \ubd84\uc790 \uba54\uc2e0\uc800\uc778 \uc0ac\uc774\ud1a0\uce74\uc778\uc744 \ubc29\ucd9c\ud558\uc5ec \ubbf8\uc138\uc544\uad50\uc138\ud3ec\ub97c \ud30c\uad34\uc801\uc778 “M1” \uc0c1\ud0dc\uc5d0\uc11c \uc870\uc9c1 \ubcf4\ud638\uc801\uc778 “M2” \uc0c1\ud0dc\ub85c \uc804\ud658\ud569\ub2c8\ub2e4. \ubc1c\ud45c\ub41c \uc2e4\ud5d8\uc2e4 \ubc0f \ub3d9\ubb3c \ubaa8\ub378 \uc5f0\uad6c\uc5d0\uc11c \uc774\ub7ec\ud55c \ubcc0\ud654\ub294 \uc5fc\uc99d\uc774 \uc0dd\uae34 \ub1cc \uc870\uc9c1\uc5d0\uc11c \uc2e0\uacbd\uc6d0 \uc0ac\ub9dd\ub960\uc744 \ub0ae\ucd94\ub294 \uac83\uc73c\ub85c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \uc704\uc5d0\uc11c \ub17c\uc758\ub41c \uc778\uac04 \ub300\uc0c1 \uc2dc\ud5d8\uc5d0\uc11c, \uc774\uac83\uc740 \uc778\ud130\ub8e8\ud0a8-6\uc744 \ud3ec\ud568\ud55c \ub1cc\ucc99\uc218\uc561 \uc5fc\uc99d \ub9c8\ucee4 \uc218\uce58\uc758 \uac10\uc18c\uc640 \uc77c\uce58\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \ub450 \ubc88\uc9f8 \uba54\ucee4\ub2c8\uc998\uc740 \uc2e0\uacbd\uc601\uc591\uc778\uc790 \uc9c0\uc6d0\uc785\ub2c8\ub2e4. MSCs\ub294 \uc720\uc0b0\uc18c \uc6b4\ub3d9\uc774 \uc790\uc5f0\uc801\uc73c\ub85c \uc99d\uac00\uc2dc\ud0a4\ub294 \uac83\uacfc \ub3d9\uc77c\ud55c \ub2e8\ubc31\uc9c8\uc778 BDNF\ub97c \ubd84\ube44\ud558\uba70, \uc2e0\uacbd\uc131\uc7a5\uc778\uc790(Nerve Growth Factor, NGF) \ubc0f \ud608\uad00\ub0b4\ud53c\uc131\uc7a5\uc778\uc790(Vascular Endothelial Growth Factor, VEGF)\ub97c \ud3ec\ud568\ud55c \ub2e4\ub978 \uc131\uc7a5 \uc778\uc790\ub3c4 \ubd84\ube44\ud569\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ubd84\uc790\ub4e4\uc740 \uae30\uc874 \uc2e0\uacbd\uc6d0\uc758 \uc0dd\uc874\uc744 \uc9c0\uc6d0\ud558\uace0, \uc2dc\ub0c5\uc2a4 \uc5f0\uacb0 \uc720\uc9c0\ub97c \uc7a5\ub824\ud558\uba70, \uc131\uc778 \ub1cc\uac00 \ubcf4\uc720\ud558\uace0 \uc788\ub294 \uc81c\ud55c\uc801\uc778 \uc2e0\uacbd \uac00\uc18c\uc131\uc744 \ucd09\uc9c4\ud569\ub2c8\ub2e4. \uc774\ub97c \ub4e4\ud310\uc5d0 \uc0c8\ub85c\uc6b4 \uc2e0\uacbd\uc6d0\uc744 \ucd94\uac00\ud558\ub294 \uac83\uc774 \uc544\ub2c8\ub77c \uae30\uc874\uc5d0 \uc788\ub358 \uc2e0\uacbd\uc6d0\uc774 \ub354 \ub098\uc740 \uc9c0\uc6d0\uc744 \ubc1b\uc544 \ub354 \uc624\ub798 \uc0dd\uc874\ud560 \uc218 \uc788\ub3c4\ub85d \uc2e0\uacbd\uc6d0\uc774 \uae30\ub2a5\ud558\ub294 \ub370 \ud544\uc694\ud55c \ud1a0\uc591 \uc870\uac74\uc744 \ubcf5\uc6d0\ud558\ub294 \uac83\uc73c\ub85c \uc0dd\uac01\ud560 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc138 \ubc88\uc9f8 \uba54\ucee4\ub2c8\uc998\uc740 \ud608\uad00 \uc9c0\uc6d0\uc785\ub2c8\ub2e4. \uc778\uc9c0 \uae30\ub2a5 \uc800\ud558, \ud2b9\ud788 \ub1cc\uc5d0 \ub300\ud55c \ub9cc\uc131\uc801\uc778 \ud608\uc561 \uacf5\uae09 \ubd80\uc871\uc73c\ub85c \uc778\ud55c \ud608\uad00\uc131 MCI\ub294 \uc2e0\uacbd\uc6d0\uc5d0 \uc0b0\uc18c\uc640 \ud3ec\ub3c4\ub2f9\uc744 \uc804\ub2ec\ud558\ub294 \uc791\uc740 \ud608\uad00\uc774 \uc190\uc0c1\ub418\uace0 \ubd80\uc801\uc808\ud574\uc9c0\ub294 \ubbf8\uc138\ud608\uad00 \uc9c8\ud658\uacfc \ubc00\uc811\ud558\uac8c \uad00\ub828\ub418\uc5b4 \uc788\uc2b5\ub2c8\ub2e4. MSCs\ub294 \uc0c8\ub85c\uc6b4 \uc791\uc740 \ud608\uad00\uc758 \ud615\uc131\uc778 \ud608\uad00 \uc2e0\uc0dd(Angiogenesis)\uc744 \ucd09\uc9c4\ud558\uace0 \uc5fc\uc99d \uc870\uc9c1\uc5d0\uc11c \ubbf8\uc138\ud608\uad00 \uae30\ub2a5\uc744 \uac1c\uc120\ud569\ub2c8\ub2e4. \uc774\uac83\uc740 \ud5c8\ud608\uc131 \uc2ec\ubd80\uc804\uc5d0\uc11c \uad00\ucc30\ub41c \uac83\uacfc \ub3d9\uc77c\ud55c \uba54\ucee4\ub2c8\uc998\uc73c\ub85c, \uc904\uae30\uc138\ud3ec\uac00 \uad00\ub958\uac00 \ubd80\uc871\ud558\uc9c0\ub9cc \uc0dd\uc874 \uac00\ub2a5\ud55c \uc2ec\uc7a5 \uc870\uc9c1\uc5d0 \ub300\ud55c \ud608\uc561 \uacf5\uae09\uc744 \uac1c\uc120\ud558\ub294 \ubc29\uc2dd\uc774\uba70, \uc774\uc81c \ub1cc\uc758 \uc720\uc0ac\ud55c \ubb38\uc81c\uc5d0 \uc801\uc6a9\ub418\ub294 \uac83\uc785\ub2c8\ub2e4. \uc911\uc694\ud55c \ud608\uad00 \uc694\uc18c\uac00 \uc788\ub294 MCI \ud658\uc790\ub294 \uc774 \uacbd\ub85c\ub97c \ud1b5\ud574 \uad6c\uccb4\uc801\uc73c\ub85c \uc774\uc810\uc744 \uc5bb\uc744 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  <\/div>\n\n\n\n

                  \ub9d0\ub808\uc774\uc2dc\uc544\uc5d0\uc11c MCI \uce58\ub8cc\uc5d0 \ub3d9\uc885 \uc81c\ub300 \uc720\ub798 MSCs\uac00 \uc0ac\uc6a9\ub418\ub294 \uc774\uc720<\/h3>\n\n\n\n

                  \uce58\ub8cc\uc5d0 \uc0ac\uc6a9\ub418\ub294 \uc138\ud3ec\uc758 \ucd9c\ucc98\ub294 \uc0ac\uc18c\ud55c \uae30\uc220\uc801 \uc138\ubd80 \uc0ac\ud56d\uc774 \uc544\ub2d9\ub2c8\ub2e4. \ub2ec\uc131\ud560 \uc218 \uc788\ub294 \uc0dd\ubb3c\ud559\uc801 \ud6a8\uacfc\uc640 \uc9c1\uc811\uc801\uc778 \uad00\ub828\uc774 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc77c\ubcf8\uc5d0\uc11c \uc7ac\uc0dd \uc758\ud559\uc758 \uaddc\uc81c \ud504\ub808\uc784\uc6cc\ud06c\ub294 \ud658\uc790 \uc790\uc2e0\uc758 \uc2e0\uccb4, \uc77c\ubc18\uc801\uc73c\ub85c \uace8\uc218\ub098 \uc9c0\ubc29 \uc870\uc9c1\uc5d0\uc11c \ucc44\ucde8\ud55c \uc138\ud3ec\ub97c \uc0ac\uc6a9\ud558\ub294 \uc790\uac00 \uc138\ud3ec \uc0ac\uc6a9\uc5d0 \uc911\uc2ec\uc744 \ub450\uace0 \uc788\uc2b5\ub2c8\ub2e4. \uadf8 \uc774\uc810\uc740 \uba74\uc5ed \uac70\ubd80 \ubc18\uc751\uc758 \uc6b0\ub824\uac00 \uc5c6\ub2e4\ub294 \uac83\uc785\ub2c8\ub2e4. \uc911\uc694\ud55c \ud55c\uacc4, \ud2b9\ud788 MCI\ub97c \uc553\uace0 \uc788\ub294 \ub178\uc778\uc758 \uacbd\uc6b0, \ub098\uc774\uac00 \ub4e4\uba74\uc11c \uc904\uae30\uc138\ud3ec\uc758 \uc9c8\uc774 \ud06c\uac8c \uc800\ud558\ub41c\ub2e4\ub294 \uc810\uc785\ub2c8\ub2e4. \uc790\uc2e0\uc758 MSCs\ub97c \uc0ac\uc6a9\ud558\uc5ec \uce58\ub8cc\ub97c \ubc1b\ub294 72\uc138 \ub178\uc778\uc740 \uc80a\uace0 \uac74\uac15\ud55c \uacf5\uc5ec\uc790\uc758 \uc138\ud3ec\uc5d0 \ube44\ud574 \uc99d\uc2dd \ub2a5\ub825\uc774 \ub208\uc5d0 \ub744\uac8c \uac10\uc18c\ud558\uace0 BDNF \ubd84\ube44\uac00 \uc801\uc73c\uba70 \ud56d\uc5fc\uc99d \ud65c\uc131\uc774 \uac10\uc18c\ud55c \uc138\ud3ec\ub97c \ud22c\uc5ec\ubc1b\uac8c \ub429\ub2c8\ub2e4. \uc5f0\ub839 \uad00\ub828 \uc2e0\uacbd \ud1f4\ud589\uc744 \ub2e4\ub8e8\uae30 \uc704\ud55c \uce58\ub8cc\uac00 \uc0ac\uc2e4\uc0c1 \ub300\uc751\ud558\uace0\uc790 \ud558\ub294 \ubc14\ub85c \uadf8 \ub178\ud654 \uacfc\uc815\uc5d0 \uc758\ud574 \uc0dd\ubb3c\ud559\uc801\uc73c\ub85c \uc81c\ud55c\uc744 \ubc1b\uac8c \ub429\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \ub9d0\ub808\uc774\uc2dc\uc544\uc5d0\uc11c \uc0ac\uc6a9\ub418\ub294 \ub3d9\uc885 \uc81c\ub300 \uc720\ub798 MSCs\ub294 \ubd84\ub9cc \uc2dc \uac74\uac15\ud55c \uc5b4\uba38\ub2c8\uac00 \uae30\uc99d\ud55c \uc81c\ub300 \uc870\uc9c1\uc5d0\uc11c \uacf5\uae09\ubc1b\uc2b5\ub2c8\ub2e4. \uc774 \uc138\ud3ec\ub4e4\uc740 \uc0dd\ubb3c\ud559\uc801 \uad00\uc810\uc5d0\uc11c \uc80a\uc2b5\ub2c8\ub2e4. \ub9cc\uc131\uc801\uc778 \uc5fc\uc99d \uc2a4\ud2b8\ub808\uc2a4\ub97c \ubc1b\ub294 70\uc138\uc758 \uc2e0\uccb4\uac00 \uc544\ub2cc \uc2e0\uc0dd\uc544 \uc870\uc9c1\uc5d0\uc11c \ucd94\ucd9c\ub418\uc5c8\uc73c\uba70, \uc131\uc778 \uae30\uc99d\uc790\uc758 \ub3d9\uc77c \uc5f0\ub839\ub300 \uc790\uac00 MSCs\ubcf4\ub2e4 \ud6e8\uc52c \ub192\uc740 \uc218\uc900\uc758 BDNF, NGF \ubc0f \ud56d\uc5fc\uc99d \uc0ac\uc774\ud1a0\uce74\uc778\uc744 \ubd84\ube44\ud558\ub294 \uac83\uc73c\ub85c \uc2e4\ud5d8\uc2e4 \ube44\uad50\uc5d0\uc11c \ub098\ud0c0\ub0ac\uc2b5\ub2c8\ub2e4. \ud45c\uc900\ud654\ub418\uace0 \ud488\uc9c8\uc774 \ud1b5\uc81c\ub41c \uc81c\uc81c\ub85c \uc0dd\uc0b0\ub418\ubbc0\ub85c \ub9e4 \uce58\ub8cc \uc804\uc5d0 \uc138\ud3ec \uc0dd\uc874\ub825\uacfc \ud6a8\ub2a5\uc774 \uac80\uc99d\ub429\ub2c8\ub2e4. \uadf8\ub9ac\uace0 \uc81c\ub300 MSCs\ub294 \uba74\uc5ed \uac70\ubd80 \ubc18\uc751\uc744 \uc720\ubc1c\ud558\ub294 \ud45c\uba74 \ub2e8\ubc31\uc9c8\uc758 \ubc1c\ud604 \uc218\uc900\uc774 \ub9e4\uc6b0 \ub0ae\uae30 \ub54c\ubb38\uc5d0 \uc784\uc0c1 \uc2e4\uc81c\uc5d0\uc11c \uc2ec\uac01\ud55c \uac70\ubd80 \ubc18\uc751\uc740 \uadf9\ud788 \ub4dc\ubb45\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uce58\ub8cc \ubaa9\ud45c\uac00 \uc138\ud3ec\uac00 \uc81c\uacf5\ud558\ub294 \uc2e0\uacbd\uc601\uc591 \ubc0f \ud56d\uc5fc\uc99d \uc2e0\ud638\uc758 \uc9c8\uacfc \ud6a8\ub2a5\uc5d0 \uc9c1\uc811\uc801\uc73c\ub85c \uc758\uc874\ud558\ub294 \uc0c1\ud0dc\uc758 \uacbd\uc6b0, \uc80a\uc740 \uacf5\uc5ec \uc138\ud3ec\uc640 \ub178\ub144\uce35 \ud658\uc790 \uc790\uc2e0\uc758 \ub178\ud654 \uc138\ud3ec \uac04\uc758 \uc0dd\ubb3c\ud559\uc801 \ucc28\uc774\ub294 \ubd80\uc218\uc801\uc778 \uac83\uc774 \uc544\ub2d9\ub2c8\ub2e4. \uadf8\uac83\uc740 \uac1c\uc785\uc774 \uc758\ubbf8 \uc788\ub294 \ud6a8\uacfc \uc784\uacc4\uac12\uc5d0 \ub3c4\ub2ec\ud560 \uc218 \uc788\ub294\uc9c0 \uc5ec\ubd80\uc758 \ud575\uc2ec\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                  <\/div>\n\n\n\n

                  \ub204\uac00 MCI \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc758 \uc88b\uc740 \ud6c4\ubcf4\uc774\uba70, \ub204\uac00 \uc544\ub2cc\uac00<\/mark><\/h2>\n\n\n\n

                  MSC \uce58\ub8cc\uc5d0 \ub354 \uc798 \ubc18\uc751\ud558\ub294 \uacbd\ud5a5\uc774 \uc788\ub294 MCI \ud504\ub85c\ud544<\/h3>\n\n\n\n

                  MCI \uc9c4\ub2e8\uc744 \ubc1b\uc740 \ubaa8\ub4e0 \uc0ac\ub78c\uc774 MSCs \uce58\ub8cc\uc758 \uc801\uc808\ud55c \ud6c4\ubcf4\uac00 \ub418\ub294 \uac83\uc740 \uc544\ub2c8\uba70, \uc800\ud76c\ub294 \uc774\uac83\uc744 \uc8fc\uc758 \uae4a\uac8c \ud3c9\uac00\ud569\ub2c8\ub2e4. \uc99d\uac70\uac00 \ud2b9\uc815 \uc0c1\ud669\uc758 \ud658\uc790\uc5d0\uac8c \uce58\ub8cc\ub97c \uc9c0\uc9c0\ud558\uc9c0 \uc54a\ub294\ub2e4\uace0 \uc0dd\uac01\ub420 \ub54c \ud658\uc790\uc5d0\uac8c \uba85\ud655\ud558\uac8c \ub9d0\ud560 \uc758\uc9c0\uac00 \uc788\ub294 \uac83\uc744 \ud3ec\ud568\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc784\uc0c1 \ub370\uc774\ud130\uc640 \uc800\ud76c\uc758 \uc790\uccb4 \ud658\uc790 \uacbd\ud5d8 \uc804\ubc18\uc5d0 \uac78\uccd0 \uac00\uc7a5 \uc77c\uad00\ub41c \uc774\uc810\uc744 \ubcf4\uc5ec\uc900 \ud504\ub85c\ud544\uc740 \uba87 \uac00\uc9c0 \ud2b9\uc9d5\uc744 \uacf5\uc720\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc9c4\ub2e8\uc774 \ucd5c\uadfc\uc5d0 \uc774\ub8e8\uc5b4\uc84c\uace0 \uc190\uc0c1 \uc815\ub3c4\uac00 \uacbd\uc99d\uc5d0\uc11c \uc911\ub4f1\ub3c4\uc778 \uacbd\uc6b0: \uc778\uc9c0 \ud14c\uc2a4\ud2b8\uc5d0\uc11c \ud658\uc790\uac00 \uc758\ubbf8 \uc788\ub294 \uc778\uc9c0 \uc608\ube44\ub825\uc774 \ub0a8\uc544 \uc788\uc74c\uc744 \ub098\ud0c0\ub0b4\ub294 \ubc94\uc704\uc5d0 \uc704\uce58\ud569\ub2c8\ub2e4. \uc77c\ubc18\uc801\uc73c\ub85c 30\uc810 \ub9cc\uc810\uc5d0 MMSE \uc810\uc218\uac00 24~28\uc810\uc774\uac70\ub098, \ubaac\ud2b8\ub9ac\uc62c \uc778\uc9c0 \ud3c9\uac00(Montreal Cognitive Assessment, MoCA) \uc810\uc218\uac00 19~25\uc810\uc778 \uacbd\uc6b0\uc785\ub2c8\ub2e4. \uac10\ud1f4\ub294 \uc9c4\ud589 \uc911\uc774\uc9c0\ub9cc \uc544\uc9c1 \uc77c\uc0c1\uc801\uc778 \ub3c5\ub9bd\uc801 \uae30\ub2a5\uc774 \ud06c\uac8c \uc190\uc0c1\ub418\ub294 \ub2e8\uacc4\uc5d0 \uc774\ub974\uc9c0\ub294 \uc54a\uc558\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \ub1cc MRI\uc0c1 \uc870\uae30 \uc2e0\uacbd\ud1f4\ud589\uc131 \ubcc0\ud654\uc640 \uc77c\uce58\ud558\ub294 \ud574\ub9c8 \uc704\ucd95\uc744 \ubcf4\uc774\ub098, \uc911\ub4f1\ub3c4\uc5d0\uc11c \uc911\uc99d \uc54c\uce20\ud558\uc774\uba38\ubcd1\uc758 \ud2b9\uc9d5\uc778 \uad11\ubc94\uc704\ud55c \ud53c\uc9c8 \uc704\ucd95\uc740 \uc5c6\ub294 \uacbd\uc6b0. \uc989, \uc0dd\uc874 \uac00\ub2a5\ud55c \uc2e0\uacbd \uad6c\uc870\uac00 \uc5ec\uc804\ud788 \uc0c1\ub2f9 \ubd80\ubd84 \uc874\uc7ac\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc804\uc2e0\uc801\uc778 \ud65c\uc131 \uc5fc\uc99d \ucc99\ub3c4\uc778 C-\ubc18\uc751\uc131 \ub2e8\ubc31\uc9c8(C-reactive protein, CRP)\uacfc, \uac00\ub2a5\ud55c \uacbd\uc6b0 \uc0c1\uc2b9\ub41c \ud0c0\uc6b0(tau) \ub2e8\ubc31\uc9c8 \ub610\ub294 p-\ud0c0\uc6b0\uc640 \uac19\uc740 \ub1cc\ucc99\uc218\uc561 \ub9c8\ucee4 \ub4f1 \uc5fc\uc99d \ub9c8\ucee4\ub4e4\uc774 MSCs \uce58\ub8cc\uc758 \ud56d\uc5fc\uc99d \uba54\ucee4\ub2c8\uc998\uc774 \uc758\ubbf8 \uc788\uac8c \uad00\uc5ec\ud560 \uc218 \uc788\ub294 \ud65c\ub3d9\uc801\uc778 \uc2e0\uacbd\uc5fc\uc99d \uacfc\uc815\uc744 \ub098\ud0c0\ub0b4\ub294 \uacbd\uc6b0. \uc785\uc99d \uac00\ub2a5\ud55c \uc2e0\uacbd\uc5fc\uc99d \uc99d\uac00\ub97c \uac00\uc9c4 \ud658\uc790\ub4e4\uc740 \uc778\uc9c0 \uae30\ub2a5 \uc800\ud558\uac00 \uc8fc\ub85c \uad6c\uc870\uc801\uc774\uac70\ub098 \uc21c\uc804\ud788 \ub300\uc0ac\uc801 \uc6d0\uc778\uc5d0 \uae30\uc778\ud55c \ud658\uc790\ub4e4\ubcf4\ub2e4 \ub354 \uc77c\uad00\ub418\uac8c \ubc18\uc751\ud558\ub294 \uac83\uc73c\ub85c \ubcf4\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \ud608\uad00 \uc704\ud5d8 \uc694\uc778(\uace0\ud608\uc555, \ub2f9\ub1e8\ubcd1 \ub610\ub294 MRI\uc5d0\uc11c \ud655\uc778 \uac00\ub2a5\ud55c \ubbf8\uc138\ud608\uad00 \uc9c8\ud658)\uc774 \uc874\uc7ac\ud558\uc9c0\ub9cc \uc801\uadf9\uc801\uc73c\ub85c \uad00\ub9ac\ub418\uace0 \uc788\ub294 \uacbd\uc6b0. \uc774\ub7ec\ud55c \ud658\uc790\uc758 \uacbd\uc6b0, MSCs \uce58\ub8cc\uc758 \ud608\uad00 \uc9c0\uc6d0 \uba54\ucee4\ub2c8\uc998\uc774 \uc2e0\uacbd\uc5fc\uc99d \uacbd\ub85c \uc774\uc0c1\uc758 \uc774\uc810\uc744 \uc81c\uacf5\ud558\uc5ec \uc774 \uce58\ub8cc\ub97c \ud2b9\uc815 \uc9c8\ubcd1 \ud504\ub85c\ud544\uc5d0 \ub300\ud55c \ubcf4\ub2e4 \ud3ec\uad04\uc801\uc778 \uc0dd\ubb3c\ud559\uc801 \uac1c\uc785\uc73c\ub85c \ub9cc\ub4e4 \uc218 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \ud658\uc790\uac00 \uc758\ud559\uc801\uc73c\ub85c \uc548\uc815\uc801\uc774\uba70, \ud65c\ub3d9\uc131 \uc545\uc131 \uc885\uc591, \uc804\uc2e0 \uac10\uc5fc \ub610\ub294 \ud1b5\uc81c\ub418\uc9c0 \uc54a\uc740 \ub300\uc0ac \uc9c8\ud658\uc774 \uc5c6\uace0, \uba74\uc5ed \uae30\ub2a5\uc744 \ud06c\uac8c \uc5b5\uc81c\ud558\ub294 \uc57d\ubb3c\uc744 \ubcf5\uc6a9\ud558\uace0 \uc788\uc9c0 \uc54a\uc740 \uacbd\uc6b0.<\/p>\n\n\n\n

                  <\/div>\n\n\n\n

                  \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uac00 MCI\uc5d0 \ub300\ud55c \uc62c\ubc14\ub978 \uae38\uc774 \uc544\ub2cc \uacbd\uc6b0<\/h3>\n\n\n\n

                  \uc800\ud76c\uac00 \uc808\ucc28\ub97c \uc9c4\ud589\ud558\uc9c0 \ub9d0\ub77c\uace0 \uba85\ud655\ud788 \uc870\uc5b8\ud558\ub294 \uc784\uc0c1 \uc0c1\ud669\ub4e4\uc774 \uc788\uc2b5\ub2c8\ub2e4. \uc774 \uba85\ud655\uc131\uc740 \ud658\uc790\ub97c \ub099\ub2f4\uc2dc\ud0a4\ub294 \uac83\uc774 \uc544\ub2c8\ub77c, \uc9c4\uc2e4\uc131\uc5d0 \uc785\uac01\ud55c \uacb0\uc815\uc758 \uae30\ucd08\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                  MCI\ub97c \ub118\uc5b4 \uacbd\ub3c4 \uce58\ub9e4\ub85c \uc9c4\ud589\ub41c \ud658\uc790(\ud2b9\ud788 MMSE \uc810\uc218\uac00 20\uc810 \ubbf8\ub9cc\uc778 \ud658\uc790)\ub294 \ub354 \uc2ec\uac01\ud558\uac8c \uc190\uc0c1\ub41c \uc2e0\uacbd \uae30\ubc18\uc744 \ub2e4\ub8e8\uace0 \uc788\ub294 \uac83\uc785\ub2c8\ub2e4. \uc774 \ub2e8\uacc4\uc5d0\uc11c\ub294 MSCs\uc758 \uc774\uc810\uc5d0 \ub300\ud55c \uc99d\uac70\uac00 \ub354 \uc57d\ud558\uba70, \uc0ac\uc6a9 \uac00\ub2a5\ud55c \uc0dd\ubb3c\ud559\uc801 \ud658\uacbd\uc774 \ub354 \uc81c\ud55c\ub429\ub2c8\ub2e4. \uc5fc\uc99d\uc774 \ud65c\uc131\ud654\ub418\uc5b4 \uc788\uc9c0\ub9cc \uad00\uc808 \ud30c\uad34\uac00 \uc544\uc9c1 \ub9d0\uae30\uc5d0 \uc774\ub974\uc9c0 \uc54a\uc558\uc744 \ub54c MSCs \uce58\ub8cc\uac00 \uac00\uc7a5 \ud6a8\uacfc\uc801\uc778 \ub958\ub9c8\ud2f0\uc2a4 \uad00\uc808\uc5fc\uacfc \ub9c8\ucc2c\uac00\uc9c0\ub85c, \uc778\uc9c0 \uae30\ub2a5 \uc800\ud558\uc5d0\uc11c\uc758 \uc904\uae30\uc138\ud3ec \uce58\ub8cc\ub294 \uad11\ubc94\uc704\ud55c \uc2e0\uacbd \uc190\uc2e4\uc774 \uc774\ubbf8 \ubc1c\uc0dd\ud558\uae30 \uc804\uc5d0 \uac00\uc7a5 \uc720\uc6a9\ud574 \ubcf4\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc778\uc9c0 \uc99d\uc0c1\uc774 \uc8fc\ub85c \uad50\uc815 \uac00\ub2a5\ud55c \uadfc\ubcf8\uc801\uc778 \uc6d0\uc778\uc5d0 \uc758\ud574 \ubc1c\uc0dd\ud558\ub294 \ud658\uc790(\uc9c4\ub2e8\ub418\uc9c0 \uc54a\uc740 \uac11\uc0c1\uc120 \uae30\ub2a5 \uc7a5\uc560, \ube44\ud0c0\ubbfc B12 \uacb0\ud54d, \uce58\ub8cc\ubc1b\uc9c0 \uc54a\uc740 \uc6b0\uc6b8\uc99d(\uc778\uc9c0 \ud14c\uc2a4\ud2b8\uc5d0\uc11c MCI\uc640 \ub9e4\uc6b0 \uc720\uc0ac\ud558\uac8c \ub098\ud0c0\ub0a0 \uc218 \uc788\uc74c), \uc57d\ubb3c \ubd80\uc791\uc6a9)\ub294 \uc5b4\ub5a4 \ucd94\uac00\uc801\uc778 \uac1c\uc785\uc744 \uace0\ub824\ud558\uae30 \uc804\uc5d0 \uc774\ub7ec\ud55c \uc6d0\uc778\uc744 \uc2dd\ubcc4\ud558\uace0 \ud574\uacb0\ud574\uc57c \ud569\ub2c8\ub2e4. B12 \uacb0\ud54d\uacfc \uad00\ub828\ub41c \uc778\uc9c0 \uae30\ub2a5 \uc800\ud558\ub97c \uc904\uae30\uc138\ud3ec\ub85c \uce58\ub8cc\ud558\ub294 \uac83\uc740 \uc0dd\ubb3c\ud559\uc801 \uac1c\uc785\uc758 \uc801\uc808\ud558\uac70\ub098 \ube44\uc6a9 \ud6a8\uc728\uc801\uc778 \uc0ac\uc6a9\uc774 \uc544\ub2d9\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \ube60\ub978 \uc644\ud654\uac00 \ud544\uc694\ud55c \ud658\uc790(\uc778\uc9c0 \ubcc0\ud654\uac00 \uc989\uac01\uc801\uc778 \uc548\uc804 \ubb38\uc81c\ub97c \uc77c\uc73c\ud0a4\uac70\ub098, \uc9c1\uc5c5\uc801 \ub610\ub294 \uac1c\uc778\uc801 \uc0c1\ud669\uc774 \ube60\ub978 \ud574\uacb0\uc744 \uc694\uad6c\ud558\ub294 \uacbd\uc6b0)\ub294 \uce58\ub8cc \ud6a8\uacfc\uac00 \ubc1c\uc0dd\ud558\ub354\ub77c\ub3c4 3\uac1c\uc6d4\uc5d0\uc11c 12\uac1c\uc6d4\uc5d0 \uac78\uccd0 \uc810\uc9c4\uc801\uc73c\ub85c \ub098\ud0c0\ub098\ub294 \uc774 \uce58\ub8cc\uc640 \uc801\ud569\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uadf8\ub9ac\uace0 \uc790\uc2e0\uc758 \uc778\uc9c0 \ub2a5\ub825\uc774 \ub354 \uc774\uc0c1 \ub5a8\uc5b4\uc9c0\uc9c0 \uc54a\uc744 \uac83\uc774\ub77c\ub294 \ubcf4\uc7a5\uc774 \ud544\uc694\ud55c \ud658\uc790\ub294 \uc5ec\uae30\uc11c\ub098 \uadf8 \uc5b4\ub514\uc5d0\uc11c\ub3c4 \uadf8\ub7ec\ud55c \ubcf4\uc7a5\uc744 \ucc3e\uc744 \uc218 \uc5c6\uc744 \uac83\uc785\ub2c8\ub2e4. MCI\uc5d0 \ub300\ud55c \uc904\uae30\uc138\ud3ec \uce58\ub8cc\ub294 \ubcf4\uc99d\uc11c\uac00 \uc544\ub2d9\ub2c8\ub2e4. \uc774\uac83\uc740 \uc77c\ubd80 \ud658\uc790\uc5d0\uac8c\uc11c \uc774\uc810\uc758 \uc99d\uac70\uac00 \uc788\ub294 \uc0dd\ubb3c\ud559\uc801 \uadfc\uac70 \uae30\ubc18\uc758 \uac1c\uc785\uc774\uba70, \uad6c\uccb4\uc801\uc73c\ub85c \ub204\uac00 \ubc18\uc751\ud560\uc9c0\uc5d0 \ub300\ud55c \uc194\uc9c1\ud55c \ubd88\ud655\uc2e4\uc131\uc774 \uc788\uace0, \ubc18\uc751\ud558\uc9c0 \uc54a\ub294 \uc0ac\ub78c\ub4e4\uc758 \ube44\uc728 \ub610\ud55c \uc758\ubbf8 \uc788\uac8c \uc874\uc7ac\ud569\ub2c8\ub2e4. \uc6b0\ub9ac\ub294 \ubaa8\ub4e0 \ucd08\uae30 \uc0c1\ub2f4\uc5d0\uc11c \ubaa8\ub4e0 \ud658\uc790\uc5d0\uac8c \uc774 \ud604\uc2e4\uc744 \uba85\ud655\ud558\uac8c \uc81c\uc2dc\ud560 \uac83\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                  <\/div>\n\n\n\n

                  \ub9d0\ub808\uc774\uc2dc\uc544\uc5d0\uc11c\uc758 MCI \uc904\uae30\uc138\ud3ec \uce58\ub8cc \ud658\uc790 \uacbd\ud5d8<\/mark><\/h2>\n\n\n\n

                  \uc0c1\ud669\uc774 \uc545\ud654\ub418\uae30 \uc804, MCI \uae30\uac04 \ub3d9\uc548 \ud589\ub3d9\ud558\uae30\ub85c \ud55c \uacb0\uc815<\/h3>\n\n\n\n

                  60\ub300 \ucd08\ubc18\uc758 \ud55c \uc5ec\uc131. \uacbd\ub825\uc744 \ud1b5\ud2c0\uc5b4 \uacb9\uacb9\uc774 \uc313\uc778 \ubcf5\uc7a1\uc131\uc744 \uc815\ubc00\ud558\uac8c \uad00\ub9ac\ud574 \uc628 \uc804\uc9c1 \uc7ac\ubb34 \ubd84\uc11d\uac00\uc600\uc2b5\ub2c8\ub2e4. \uc57d 2\ub144\uc758 \uae30\uac04 \ub3d9\uc548, \uadf8\ub140\ub294 \ucc98\uc74c\uc5d0\ub294 \uc5c5\ubb34 \uc2a4\ud2b8\ub808\uc2a4 \ud0d3\uc73c\ub85c \ub3cc\ub838\ub358 \ubcc0\ud654\ub97c \uc54c\uc544\ucc28\ub838\uc2b5\ub2c8\ub2e4. \uc774\ub984\uc744 \ub5a0\uc62c\ub9ac\ub294 \ub370 \uc2dc\uac04\uc774 \ub354 \uc624\ub798 \uac78\ub9ac\uace0, \ucd5c\uadfc \ub300\ud654\uc758 \uc138\ubd80 \uc0ac\ud56d\uc774 \uc801\uc5b4\ub450\uae30 \uc804\uc5d0 \uc0ac\ub77c\uc9c0\uace0, \uc608\uc804\uc5d0\ub294 \uc804\ud600 \ub178\ub825\uc774 \ud544\uc694\ud558\uc9c0 \uc54a\uc558\ub358 \ud68c\uc758\uc5d0\uc11c \uc5ec\ub7ec \uac00\uc9c0\uac00 \ub3d9\uc2dc\uc5d0 \uc9c4\ud589\ub418\ub294 \ub9e5\ub77d\uc744 \ucd94\uc801\ud558\ub294 \ub370 \uc5b4\ub824\uc6c0\uc744 \uacaa\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc2e0\uacbd\uc2ec\ub9ac\ud559\uc801 \ud14c\uc2a4\ud2b8 \uacb0\uacfc, \uadf8\ub140\ub294 \ud655\uc2e4\ud788 \uae30\uc5b5\uc0c1\uc2e4\ud615 MCI \ubc94\uc704\uc5d0 \uc18d\ud588\uc2b5\ub2c8\ub2e4. \ub2e4\ub978 \uc778\uc9c0 \uae30\ub2a5\uc758 \uc2ec\uac01\ud55c \uc190\uc0c1 \uc5c6\uc774 \uae30\uc5b5\ub825\uc5d0 \ud2b9\ud654\ub41c \uc800\ud558\uc600\uc2b5\ub2c8\ub2e4. \uadf8\ub140\uc758 MRI\ub294 \ucd08\uae30 \uc2e0\uacbd\ud1f4\ud589\uc131 \ubcc0\ud654\uc640 \uc77c\uce58\ud558\ub294 \uacbd\ubbf8\ud55c \uc591\uce21\uc131 \ud574\ub9c8 \ubd80\ud53c \uac10\uc18c\ub97c \ubcf4\uc5ec\uc8fc\uc5c8\uc2b5\ub2c8\ub2e4. \uadf8\ub140\uc758 \uc2e0\uacbd\uacfc \uc804\ubb38\uc758\ub294 \uac00\uc5ed\uc801\uc778 \uc6d0\uc778\uc774 \uc5c6\uc74c\uc744 \ud655\uc778\ud558\uace0 \uc720\uc0b0\uc18c \uc6b4\ub3d9 \ubc0f \uc778\uc9c0 \ud65c\ub3d9\uacfc \ud568\uaed8 \ub9e4\ub144 \ubaa8\ub2c8\ud130\ub9c1\uc744 \uad8c\uc7a5\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uadf8\ub140\uac00 \uc6b0\ub9ac \ud074\ub9ac\ub2c9\uc744 \ucc3e\uc740 \uac83\uc740 \uc778\uc9c0 \uae30\ub2a5\uc774 \uc2ec\ud558\uac8c \uc190\uc0c1\ub418\uc5c8\uae30 \ub54c\ubb38\uc774 \uc544\ub2c8\ub77c, \uc815\ud655\ud788 \uc544\uc9c1 \uadf8\ub807\uc9c0 \uc54a\uc558\uae30 \ub54c\ubb38\uc774\uc5c8\uc2b5\ub2c8\ub2e4. \uadf8\ub140\ub294 \uac1c\uc785\uc774 \uc2e0\uacbd \ud658\uacbd\uc744 \ub354 \uc77c\ucc0d \uc9c0\uc6d0\ud560\uc218\ub85d \ubcf4\ud638\ud574\uc57c \ud560 \ub300\uc0c1\uc774 \ub354 \ub9ce\uc544\uc9c4\ub2e4\ub294 \uac83\uc744 \uba85\ud655\ud788 \uc774\ud574\ud558\uace0 \uc788\uc5c8\uc2b5\ub2c8\ub2e4. \uadf8\ub140\ub294 \uccab \uc0c1\ub2f4 \uc804\uc5d0 \ubc1c\ud45c\ub41c \uc2dc\ud5d8 \ub370\uc774\ud130\ub97c \uac80\ud1a0\ud588\uace0, \uc99d\uac70\uac00 \ubb34\uc5c7\uc744 \ubcf4\uc5ec\uc8fc\uace0 \ubb34\uc5c7\uc744 \ubcf4\uc5ec\uc8fc\uc9c0 \uc54a\ub294\uc9c0\uc5d0 \ub300\ud55c \uad6c\uccb4\uc801\uc774\uace0 \uae30\uc220\uc801\uc778 \uc9c0\uc2dd\uc774 \ub2f4\uae34 \uc9c8\ubb38\uc744 \uac00\uc838\uc654\uc2b5\ub2c8\ub2e4. \uadf8\ub140\ub294 \uc57d\uc18d\uc744 \uc6d0\ud55c \uac83\uc774 \uc544\ub2c8\uc5c8\uc2b5\ub2c8\ub2e4. \uc0dd\ubb3c\ud559\uc801\uc73c\ub85c \uc194\uc9c1\ud55c \ub300\ud654\ub97c \uc6d0\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uce58\ub8cc\ub97c \uc218\ub77d\ud558\uae30 \uc804\uc5d0 \uc6b0\ub9ac\ub294 \uadf8\ub140\uc758 \uc2e0\uacbd\uc2ec\ub9ac\ud559\uc801 \ud3c9\uac00, MRI, \uc5fc\uc99d \ub9c8\ucee4 \ubc0f \uc804\uccb4 \uc57d\ubb3c \uae30\ub85d\uc744 \uac80\ud1a0\ud588\uc2b5\ub2c8\ub2e4. \uadf8\ub140\ub294 MSCs \uce58\ub8cc\uac00 \uc0dd\ubb3c\ud559\uc801\uc73c\ub85c \ud0c0\ub2f9\ud558\uace0 \uc99d\uac70\uac00 \ub4b7\ubc1b\uce68\ub418\ub294 \ud658\uc790\uc758 \ud504\ub85c\ud544\uc744 \ucda9\uc871\ud588\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  <\/div>\n\n\n\n

                  MCI \uc904\uae30\uc138\ud3ec \uce58\ub8cc \ud6c4 \ubcc0\ud654\ub41c \uac83 – \uadf8\ub9ac\uace0 \ubcc0\ud654\ub418\uc9c0 \uc54a\uc740 \uac83<\/h3>\n\n\n\n

                  \uc815\ub9e5\uc73c\ub85c MSCs\ub97c \uc8fc\uc785\ud55c \ud6c4 \ucc98\uc74c 8\uc8fc \ub3d9\uc548\uc740 \uadf8\ub140\uac00 \uc2dd\ubcc4\ud560 \uc218 \uc788\ub294 \ubcc0\ud654\uac00 \uc5c6\uc5c8\uc2b5\ub2c8\ub2e4. \uc774\uac83\uc740 \uc608\uc0c1\ub418\ub294 \uc7a0\ubcf5\uae30\uc600\uc73c\uba70, \uadf8\ub140\ub294 \uc774\ub97c \uc608\uc0c1\ud558\ub77c\ub294 \uba85\uc2dc\uc801\uc778 \uc9c0\uc2dc\ub97c \ubc1b\uc558\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc138 \ubc88\uc9f8 \ub2ec\uc5d0 \uc811\uc5b4\ub4e4\uba74\uc11c, \uadf8\ub140\ub294 \ub9d0\ub85c \ud45c\ud604\ud558\uae30 \uc5b4\ub824\uc6b4 \uac83\uc744 \ubb18\uc0ac\ud588\uc2b5\ub2c8\ub2e4. \uadf8\ub140\uac00 “\uc778\uc9c0\uc801 \ub178\ub825”\uc774\ub77c\uace0 \ubd80\ub974\ub294 \uac83\uc774 \uc904\uc5b4\ub4e0 \uac83\uc785\ub2c8\ub2e4. \ubcf5\uc7a1\ud55c \ub300\ud654\ub97c \ub530\ub77c\uac00\uac70\ub098, \uc77c\ub828\uc758 \uc9c0\uc2dc \uc0ac\ud56d\uc744 \uae30\uc5b5\ud558\uac70\ub098, \ucd5c\uadfc\uc5d0 \ub4e4\uc740 \uc774\ub984\uc744 \ub5a0\uc62c\ub9ac\ub294 \ub4f1 \ub208\uc5d0 \ub744\ub294 \uc815\uc2e0\uc801 \uc5d0\ub108\uc9c0\uac00 \ud544\uc694\ud588\ub358 \uc791\uc5c5\ub4e4\uc774 \uc870\uae08 \ub35c \ud798\ub4e4\uac8c \ub290\uaef4\uc84c\uc2b5\ub2c8\ub2e4. \uc218\uc6d4\ud574\uc9c4 \uac83\uc740 \uc544\ub2d9\ub2c8\ub2e4. \uadf8\uc800 \uc57d\uac04 \ub35c \ud798\ub4e4\uc5b4\uc9c4 \uac83\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                  6\uac1c\uc6d4\uc9f8 \ud3c9\uac00\uc5d0\uc11c \uadf8\ub140\uc758 \uc2e0\uacbd\uc2ec\ub9ac\ud559\uc801 \uc7ac\ud3c9\uac00\ub294 \ubaa8\ub4e0 \ud14c\uc2a4\ud2b8 \uc601\uc5ed\uc5d0 \uac78\uccd0 \uc548\uc815\uc801\uc778 \uc810\uc218\ub97c \ubcf4\uc600\uc2b5\ub2c8\ub2e4. \uae30\uc900\uc120\uc5d0\uc11c \uce21\uc815 \uac00\ub2a5\ud55c \ud558\ub77d\uc774 \uc5c6\uc5c8\uc2b5\ub2c8\ub2e4. \uc774\ub294 \uac1c\uc785\uc774 \uc5c6\uc5c8\ub2e4\uba74 \ud1b5\uacc4\uc801\uc73c\ub85c \uc608\uc0c1\ub418\uc5c8\uc744 \uc5f0\uac04 \uc57d 2\uc810\uc758 MMSE \ud558\ub77d\uacfc \ub69c\ub837\ud55c \ub300\uc870\ub97c \uc774\ub8f9\ub2c8\ub2e4. \uc77c\uc0c1\uc801\uc778 \uc778\uc9c0 \uacfc\uc81c\uc5d0 \ub300\ud574 \uadf8\ub140 \uc2a4\uc2a4\ub85c \ubcf4\uace0\ud55c \uc790\uc2e0\uac10\uc774 \ud5a5\uc0c1\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uc9c4\ub2e8 \uada4\uc801\uc5d0 \ub300\ud55c \ubd88\uc548 \uac10\uc18c\uac00 \ubd80\ubd84\uc801\uc778 \uc6d0\uc778\uc774 \ub418\uc5b4 \uc218\uba74\uc758 \uc9c8\ub3c4 \uac1c\uc120\ub418\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  12\uac1c\uc6d4\uc774 \ub418\uc5c8\uc744 \ub54c \uc0c1\ud669\uc740 \uc548\uc815\uc801\uc73c\ub85c \uc720\uc9c0\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uadf8\ub140\ub294 \uc9c0\ub09c 2\ub144 \ub3d9\uc548 \uc778\uc9c0\ud588\ub358 \uae30\uc5b5\ub825 \ubcc0\ud654\uc758 \uc5ed\uc804\uc744 \uacbd\ud5d8\ud558\uc9c0\ub294 \uc54a\uc558\uc2b5\ub2c8\ub2e4. \uadf8\ub140\ub294 \uc774 \uc810\uc5d0 \ub300\ud574 \uba85\ud655\ud558\uac8c \uc778\uc2dd\ud558\uace0 \uc788\uc5c8\uc2b5\ub2c8\ub2e4. \uc5ec\uc804\ud788 \ub2e8\uc5b4\ub97c \ucc3e\uc73c\ub824 \uc560\uc37c\uace0, \uc77c\ubd80 \uc774\ub984\uc740 \uc608\uc804\ubcf4\ub2e4 \uac80\uc0c9\ud558\uae30 \ub354 \uc5b4\ub835\ub2e4\ub294 \uac83\uc744 \uc5ec\uc804\ud788 \ubc1c\uacac\ud588\uc2b5\ub2c8\ub2e4. \ubcc0\ud654\ub41c \uac83\uc740 \uada4\uc801\uc774\uc5c8\uc2b5\ub2c8\ub2e4. \uc0c1\ud669\uc774 \uacc4\uc18d \uc545\ud654\ub418\ub294 \uac83\uc774 \uc544\ub2c8\ub77c \uc548\uc815\uc801\uc774\ub77c\ub294 \ub290\ub08c\uc774\uc5c8\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uadf8\ub140\ub294 \uc5f0\ub840 \ubaa8\ub2c8\ud130\ub9c1\uc744 \uacc4\uc18d\ud560 \uac83\uc774\uba70 \ud6c4\uc18d \ud3c9\uac00 \uacb0\uacfc\uc5d0 \ub530\ub77c \ub450 \ubc88\uc9f8 \uc8fc\uc785 \uac00\ub2a5\uc131\ub3c4 \ubc30\uc81c\ud558\uc9c0 \uc54a\uc558\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc774 \uc124\uba85\uc740 \ud658\uc790\uc758 \ub3d9\uc758\ud558\uc5d0 \uc775\uba85\uc73c\ub85c \ucc98\ub9ac\ub418\uc5c8\uc2b5\ub2c8\ub2e4. \uac1c\ubcc4 \uacb0\uacfc\ub294 \ud06c\uac8c \ub2e4\ub974\uba70 \ubcf4\uc7a5\ud560 \uc218 \uc5c6\uc2b5\ub2c8\ub2e4. \uc774 \uacbd\ud5d8\uc740 \ubaa8\ub4e0 \ud658\uc790\uac00 \uacbd\ud5d8\ud558\uac8c \ub420 \uac83\uc744 \ub300\ud45c\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  <\/div>\n\n\n\n

                  MCI \uc904\uae30\uc138\ud3ec \uce58\ub8cc \ud6c4\uc758 \ud68c\ubcf5 \ubc0f \ucd94\uc801 \uad00\ucc30<\/h3>\n\n\n\n

                  \uc815\ub9e5 MSCs \uc8fc\uc785 \ud6c4 \ud68c\ubcf5 \uacfc\uc815\uc5d0\uc11c \uc2e0\uccb4\uc801\uc778 \ubb34\ub9ac\ub294 \uc5c6\uc2b5\ub2c8\ub2e4. \ub300\ubd80\ubd84\uc758 \ud658\uc790\ub294 \uc2dc\uc220 \ud6c4 2~3\uc77c \uc774\ub0b4\uc5d0 \ud3b8\uc548\ud558\uac8c \uc9d1\uc73c\ub85c \ub3cc\uc544\uac11\ub2c8\ub2e4. \uc815\uc0c1\uc801\uc778 \uc77c\uc0c1 \ud65c\ub3d9\uc73c\ub85c\uc758 \ubcf5\uadc0\ub294 \uc77c\ubc18\uc801\uc73c\ub85c 1\uc8fc\uc77c \uc774\ub0b4\uc5d0 \uc774\ub8e8\uc5b4\uc9d1\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uce58\ub8cc \ud6c4 \uae30\uac04\uc5d0\uc11c \uac00\uc7a5 \uc911\uc694\ud55c \uce21\uba74\uc740 \uc2dc\uac04 \uc77c\uc815\uc5d0 \ub300\ud55c \uc778\ub0b4\uc2ec\uc785\ub2c8\ub2e4. \uba87 \uc2dc\uac04 \ub0b4\uc5d0 \uc791\uc6a9\ud558\ub294 \uc9c4\ud1b5\uc81c\ub098 \uba70\uce60 \ub0b4\uc5d0 \uc5fc\uc99d\uc744 \uc904\uc774\ub294 \ucf54\ub974\ud2f0\uc190 \uc8fc\uc0ac\uc640 \uac19\uc740 \uae09\uc131 \uce58\ub8cc\uc640 \ub2ec\ub9ac, MSCs \uce58\ub8cc\ub294 \ub290\ub9b0 \uc0dd\ubb3c\ud559\uc801 \uacfc\uc815\uc744 \ud1b5\ud574 \uc791\uc6a9\ud569\ub2c8\ub2e4. \uc5fc\uc99d \ubd80\uc704\ub85c\uc758 \uc774\ub3d9, \uc9c0\uc18d\uc801\uc778 \uc2e0\uacbd\uc601\uc591\uc778\uc790 \ubd84\ube44, \uc810\uc9c4\uc801\uc778 \ubbf8\uc138\uc544\uad50\uc138\ud3ec \uc870\uc808 \ub4f1\uc774 \uadf8\uac83\uc785\ub2c8\ub2e4. \uc774\ub7ec\ud55c \uacfc\uc815\uc774 \ud658\uc790\ub098 \uacf5\uc2dd\uc801\uc778 \ud14c\uc2a4\ud2b8\uc5d0\uc11c \uac10\uc9c0\ud560 \uc218 \uc788\ub294 \ud6a8\uacfc\ub97c \ub0b4\uae30\uae4c\uc9c0\ub294 \uba87 \uc8fc\uc5d0\uc11c \uba87 \ub2ec\uc774 \uac78\ub9bd\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \ucc98\uc74c 4\uc8fc \uc774\ub0b4\uc5d0 \uc758\ubbf8 \uc788\ub294 \ubcc0\ud654\ub97c \uae30\ub300\ud558\uace0 \uc624\ub294 \ud658\uc790\ub294 \uc2e4\ub9dd\ud558\uac8c \ub420 \uac83\uc774\uba70, \uadf8 \uc2e4\ub9dd\uc740 \uce58\ub8cc\uac00 \ud6a8\uacfc\uac00 \uc5c6\ub2e4\ub294 \ubd80\uc815\ud655\ud55c \uc870\uae30 \uacb0\ub860\uc73c\ub85c \uc774\uc5b4\uc9c8 \uc218 \uc788\uc2b5\ub2c8\ub2e4. \uc77c\uc815\ud45c\ub97c \uc774\ud574\ud558\uace0 \uac1d\uad00\uc801\uc778 6\uac1c\uc6d4 \uc7ac\ud3c9\uac00\ub97c \ud3ec\ud568\ud558\ub294 \uccb4\uacc4\uc801\uc778 \ucd94\uc801 \uacc4\ud68d\uc744 \uac00\uc9c4 \ud658\uc790\uac00 \uc790\uc2e0\uc758 \ubc18\uc751\uc744 \uacf5\uc815\ud558\uac8c \ud3c9\uac00\ud560 \uc218 \uc788\ub294 \ub354 \ub098\uc740 \uc704\uce58\uc5d0 \uc788\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  <\/div>\n\n\n\n

                  \uacbd\ub3c4\uc778\uc9c0\uc7a5\uc560\uc5d0 \ub300\ud55c \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc758 \uc194\uc9c1\ud55c \uc704\ud5d8\uacfc \ud55c\uacc4<\/mark><\/h2>\n\n\n\n

                  MCI\uc5d0 \ub300\ud574 \uc54c\ub824\uc9c4 \ubd80\uc791\uc6a9 \ubc0f \uc548\uc804 \ub370\uc774\ud130<\/h3>\n\n\n\n

                  \ubc1c\ud45c\ub41c \uc784\uc0c1 \uc2dc\ud5d8 \ubc0f \uc784\uc0c1 \uacbd\ud5d8 \uc804\ubc18\uc5d0 \uac78\uccd0 \uc815\ub9e5 \ud22c\uc5ec \ub3d9\uc885 MSCs \uce58\ub8cc\uc758 \uc548\uc804\uc131 \ud504\ub85c\ud544\uc740 \uc815\ub9e5 \ud22c\uc5ec \uacbd\ub85c\uc758 \uacbd\uc6b0 \uc77c\uad00\ub418\uac8c \uc720\ub9ac\ud588\uc2b5\ub2c8\ub2e4. \uc774 \uc810\uc740 \uba85\ud655\ud788 \uae30\ub85d\ud560 \uac00\uce58\uac00 \uc788\uc73c\uba70 \ub610\ud55c \ub9e5\ub77d\uc744 \ud30c\uc545\ud560 \uac00\uce58\ub3c4 \uc788\uc2b5\ub2c8\ub2e4. \ub9d0\ub808\uc774\uc2dc\uc544\uc5d0\uc11c \uc0ac\uc6a9\ub418\ub294 IV \uc811\uadfc\ubc95\uc758 \uc704\ud5d8 \ud504\ub85c\ud544\uc740 \uc138\ud3ec\ub97c \ub1cc\ub098 \ub1cc\ucc99\uc218\uc561 \uacf5\uac04\uc5d0 \uc9c1\uc811 \uc8fc\uc785\ud558\ub294 \uc2dc\ud5d8\uacfc \ud06c\uac8c \ub2e4\ub985\ub2c8\ub2e4. \uc774\ub294 \ub354 \ub192\uc740 \uc2dc\uc220 \uc704\ud5d8\uacfc \uad00\ub828\ub41c \uc811\uadfc\ubc95\uc774\ubbc0\ub85c \uc800\ud76c\ub294 \uc0ac\uc6a9\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  IV MSCs \uc8fc\uc785 \ud6c4 \uac00\uc7a5 \ud754\ud558\uac8c \ubcf4\uace0\ub418\ub294 \ud6a8\uacfc\ub294 \uacbd\ubbf8\ud558\uace0 \uc790\uac00 \uc81c\ud55c\uc801\uc785\ub2c8\ub2e4. \uc57d 15~20%\uc758 \ud658\uc790\uac00 \ubcf4\uace0\ud558\ub294 \uc8fc\uc785 \ud6c4 24~48\uc2dc\uac04 \ub0b4\uc758 \ubbf8\uc5f4\uc740 \uae30\uc99d\uc790 \uc138\ud3ec\uc5d0 \ub300\ud55c \uba74\uc5ed\uacc4\uc758 \uc778\uc2dd\uc744 \ubc18\uc601\ud558\uba70 \uac10\uc5fc\uc774 \uc544\ub2d9\ub2c8\ub2e4. \uc8fc\uc785 \ud6c4 1~3\uc77c \ub3d9\uc548\uc758 \uc77c\uc2dc\uc801\uc778 \ud53c\ub85c\uac10\uc774 \ud754\ud569\ub2c8\ub2e4. \uccab 48\uc2dc\uac04 \ub0b4\uc5d0 \uac00\ub054 \uac00\ubcbc\uc6b4 \ub450\ud1b5\uc774 \ubcf4\uace0\ub418\uae30\ub3c4 \ud569\ub2c8\ub2e4. \uc774\ub7ec\ud55c \ud6a8\uacfc\ub294 \ub300\ub2e4\uc218\uc758 \uacbd\uc6b0 \uc758\ud559\uc801 \uac1c\uc785 \uc5c6\uc774 \uc2a4\uc2a4\ub85c \ud574\uacb0\ub429\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc815\ub9e5 \ud22c\uc5ec\ub97c \ud3ec\ud568\ud558\ub294 \uc54c\uce20\ud558\uc774\uba38\ubcd1 \ub610\ub294 MCI \uc9d1\ub2e8 \ub300\uc0c1\uc758 \ubc1c\ud45c\ub41c \uc784\uc0c1 \uc2dc\ud5d8\uc5d0\uc11c \ub1cc\uc878\uc911, \uc885\uc591 \ud615\uc131 \ub610\ub294 \uc2ec\uac01\ud55c \uba74\uc5ed \uac70\ubd80 \ubc18\uc751\uc744 \ud3ec\ud568\ud558\uc5ec \uc815\ub9e5 MSCs \uc8fc\uc785\uc5d0 \uc9c1\uc811 \uae30\uc778\ud55c \uc2ec\uac01\ud55c \ubd80\uc791\uc6a9\uc740 \uad00\ucc30\ub418\uc9c0 \uc54a\uc558\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uae30\uc874\uc5d0 \uc2ec\ud608\uad00 \uc9c8\ud658\uc5d0 \ucde8\uc57d\ud560 \uc218 \uc788\ub294 \uace0\ub839 \uc131\uc778\uc758 \uacbd\uc6b0, \uce58\ub8cc \uc804 \uc2ec\ud608\uad00 \uac80\uc9c4\uc774 \ub2f9\uc0ac\uc758 \ud45c\uc900 \uc801\uaca9\uc131 \uac80\ud1a0\uc758 \uc77c\ubd80\uc785\ub2c8\ub2e4. \uc2ec\uac01\ud55c \uc2ec\uc7a5 \uc9c8\ud658\uc774 \uc788\ub294 \ud658\uc790\ub294 \uc8fc\uc785\uc744 \uad8c\uc7a5\ud558\uae30 \uc804\uc5d0 \uac1c\ubcc4\uc801\uc73c\ub85c \ud3c9\uac00\ub429\ub2c8\ub2e4.<\/p>\n\n\n\n

                  <\/div>\n\n\n\n

                  \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uac00 \uacbd\ub3c4\uc778\uc9c0\uc7a5\uc560\uc5d0 \ud560 \uc218 \uc5c6\ub294 \uac83ild Cognitive Impairment<\/h3>\n\n\n\n

                  \uc774 \uc139\uc158\uc740 \uc774 \uae00\uc758 \ub2e4\ub978 \uc5b4\ub5a4 \ubd80\ubd84 \ubabb\uc9c0\uc54a\uac8c \uc911\uc694\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

                  MSCs \uce58\ub8cc\ub294 \uc774\ubbf8 \uc783\uc5b4\ubc84\ub9b0 \uae30\uc5b5\uc744 \ud68c\ubcf5\ud560 \uc218 \uc5c6\uc2b5\ub2c8\ub2e4. \uc774\ubbf8 \uc8fd\uc740 \uc2e0\uacbd\uc6d0\uc740 \uc774 \uac1c\uc785\uc744 \ud1b5\ud574 \uc7ac\uc0dd\ub418\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \uc601\uad6c\uc801\uc73c\ub85c \ub04a\uc5b4\uc9c4 \uc5f0\uacb0\uc740 \ub2e4\uc2dc \ud615\uc131\ub420 \uc218 \uc5c6\uc2b5\ub2c8\ub2e4. \uc774 \uce58\ub8cc\ub294 \uc0dd\uc874\ud55c \uc2e0\uacbd\uc6d0 \uc8fc\ubcc0\uc758 \uc138\ud3ec \ud658\uacbd\uc744 \uaca8\ub0e5\ud558\uc5ec \uc9c0\uc18d\uc801\uc778 \uc190\uc0c1\uc744 \ub2a6\ucd94\ub294 \uac83\uc774\uc9c0 \uc774\ubbf8 \ucd95\uc801\ub41c \uac83\uc744 \ub418\ub3cc\ub9ac\ub294 \uac83\uc774 \uc544\ub2d9\ub2c8\ub2e4.<\/p>\n\n\n\n

                  MSCs \uce58\ub8cc\ub294 \uce58\ub9e4\ub85c\uc758 \uc9c4\ud589\uc744 \ud655\uc2e4\ud788 \uc608\ubc29\ud560 \uc218 \uc5c6\uc2b5\ub2c8\ub2e4. \uce58\ub8cc\uc5d0 \ubc18\uc751\ud558\ub294 \ud658\uc790\ub77c\ub3c4 MCI\uc758 \uadfc\ubcf8\uc801\uc778 \uc0dd\ubb3c\ud559\uc801 \uacfc\uc815(\uc54c\uce20\ud558\uc774\uba38 \ubcd1\ub9ac\uc5d0 \uc758\ud574 \uc720\ubc1c\ub418\ub294 \uacbd\uc6b0)\uc740 \ub2e8 \ud55c \ubc88\uc758 \uc8fc\uc785\uc73c\ub85c \uc18c\uba78\ub418\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \uce58\ub8cc\ub294 \uc774\ub97c \ub2a6\ucd9c \uc218\ub294 \uc788\uc2b5\ub2c8\ub2e4. \ud558\uc9c0\ub9cc \ub9c9\uc544\uc900\ub2e4\uace0 \ubcf4\uc7a5\ud560 \uc218\ub294 \uc5c6\uc2b5\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc774 \uc801\uc751\uc99d\uc5d0 \ub300\ud55c \uc7a5\uae30 \uacb0\uacfc \ub370\uc774\ud130\ub294 \uc544\uc9c1 \ubc1c\ud45c\ub41c \ud615\ud0dc\ub85c \uc874\uc7ac\ud558\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \uac00\uc7a5 \uad00\ub828\uc131 \ub192\uc740 \uc778\uccb4 \ub300\uc0c1 \uc784\uc0c1 \uc2dc\ud5d8\uc5d0\uc11c \uac00\uc7a5 \uae34 \ucd94\uc801 \uae30\uac04\uc740 2~3\ub144\uc785\ub2c8\ub2e4. \ubc18\ubcf5\uc801\uc778 \uc8fc\uc785\uc774 \uc2dc\uac04\uc774 \uc9c0\ub0a8\uc5d0 \ub530\ub77c \uc774\uc810\uc774 \uc788\ub294\uc9c0, \uce58\ub8cc \uac04\uc758 \ucd5c\uc801 \uac04\uaca9\uc774 \ubb34\uc5c7\uc778\uc9c0, \uadf8\ub9ac\uace0 \uadf8 \ud6a8\uacfc\uac00 \uc5bc\ub9c8\ub098 \uc9c0\uc18d\uc801\uc778\uc9c0\ub294 \uc5ec\uc804\ud788 \uc5f4\ub824\uc788\ub294 \uc784\uc0c1 \uc9c8\ubb38\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uce58\ub8cc \uc804\uc5d0 \uc5b4\ub5a4 MCI \ud658\uc790\uac00 \ubc18\uc751\ud560\uc9c0, \uc5b4\ub5a4 \ud658\uc790\uac00 \ubc18\uc751\ud558\uc9c0 \uc54a\uc744\uc9c0 \ud655\uc2e4\ud558\uac8c \uc608\uce21\ud560 \uc218 \uc788\ub294 \uc0dd\uccb4 \ub9c8\ucee4(\ubc14\uc774\uc624\ub9c8\ucee4)\ub294 \uc5c6\uc2b5\ub2c8\ub2e4. \uc6b0\ub9ac\uc758 \uce58\ub8cc \uc804 \ud3c9\uac00\ub294 \uc0ac\uc6a9 \uac00\ub2a5\ud55c \ucd5c\uc0c1\uc758 \uc9c0\uce68\uc744 \uc81c\uacf5\ud558\uba70, \uc784\uc0c1\uc801 \uc0c1\ud669\uc5d0 \uae30\ubc18\ud558\uc5ec \uc815\uc9c1\ud55c \ud310\ub2e8\uc744 \uacf5\uc720\ud560 \uac83\uc774\uc9c0\ub9cc \uc774 \uacfc\uc815\uc5d0\ub294 \ubcf8\uc9c8\uc801\uc73c\ub85c \ubd88\ud655\uc2e4\uc131\uc774 \uc874\uc7ac\ud569\ub2c8\ub2e4.<\/p>\n\n\n\n

                  \uc774\ub7ec\ud55c \ud55c\uacc4\uac00 \uc774\uc6a9 \uac00\ub2a5\ud55c \uc99d\uac70\ub97c \ubb34\uc2dc\ud560 \uc774\uc720\ub294 \ub418\uc9c0 \uc54a\uc2b5\ub2c8\ub2e4. \uc774\ub294 \uadf8 \uc99d\uac70\ub97c \uc77d\uc5b4\uc57c \ud560, \uadf8\ub9ac\uace0 \uce58\ub8cc\uc5d0 \ub300\ud55c \uc5b4\ub5a0\ud55c \uacb0\uc815\uc774\ub4e0 \ub0b4\ub824\uc838\uc57c \ud560 \uc815\uc9c1\ud55c \ubc30\uacbd\uc785\ub2c8\ub2e4.<\/p>\n\n\n\n

                  <\/div>\n\n\n\n

                  \uacbd\ub3c4\uc778\uc9c0\uc7a5\uc560 \uc904\uae30\uc138\ud3ec \uce58\ub8cc\uc5d0 \ub300\ud55c FAQ<\/mark><\/h2>\n\n\n\n
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