{"id":25177,"date":"2026-05-19T08:22:18","date_gmt":"2026-05-19T00:22:18","guid":{"rendered":"https:\/\/stemcell-malaysia.com\/?page_id=25177"},"modified":"2026-07-31T12:26:36","modified_gmt":"2026-07-31T04:26:36","slug":"multiple-sclerosis","status":"publish","type":"page","link":"https:\/\/stemcell-malaysia.com\/ja\/conditions\/multiple-sclerosis\/","title":{"rendered":"\u591a\u767a\u6027\u786c\u5316\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\uff5c\u5316\u5b66\u7642\u6cd5\u306b\u983c\u3089\u305aDMT\u3067\u6b62\u307e\u3089\u306a\u3044\u9032\u884c\u3092\u9045\u3089\u305b\u308b\u65b0\u3057\u3044\u9078\u629e\u80a2"},"content":{"rendered":"\n<h1 class=\"wp-block-heading has-text-align-center\">\u591a\u767a\u6027\u786c\u5316\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\uff5c\u5316\u5b66\u7642\u6cd5\u306b\u983c\u3089\u305aDMT\u3067\u6b62\u307e\u3089\u306a\u3044\u9032\u884c\u3092\u9045\u3089\u305b\u308b\u65b0\u3057\u3044\u9078\u629e\u80a2<\/h1>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"436\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Gemini_Generated_Image_4m8nzj4m8nzj4m8n.webp\" alt=\"\u671d\u306e\u8d77\u5e8a\u6642\u306b\u8eab\u4f53\u306e\u3060\u308b\u3055\u3068\u811a\u306e\u611f\u899a\u7570\u5e38\u3092\u611f\u3058\u3066\u3044\u308b\u591a\u767a\u6027\u786c\u5316\u75c7\u306e\u5973\u6027\" class=\"wp-image-25170\" style=\"aspect-ratio:1.8348992638512205;width:650px;height:auto\" srcset=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Gemini_Generated_Image_4m8nzj4m8nzj4m8n.webp 800w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Gemini_Generated_Image_4m8nzj4m8nzj4m8n-300x164.webp 300w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Gemini_Generated_Image_4m8nzj4m8nzj4m8n-768x419.webp 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption 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style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u76ee\u6b21<\/mark><\/h2>\n\n\n<div class=\"wp-block-aioseo-table-of-contents\"><ol><li><a class=\"aioseo-toc-item\" href=\"#aioseo-why-multiple-sclerosis-continues-to-progress-even-on-treatment-6\">\u591a\u767a\u6027\u786c\u5316\u75c7\u306f\u306a\u305cDMT\u3092\u4f7f\u3063\u3066\u3082\u9032\u884c\u3059\u308b\u3053\u3068\u304c\u3042\u308b\u306e\u304b<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u591a\u767a\u6027\u786c\u5316\u75c7\u306e\u75be\u60a3\u4fee\u98fe\u85ac\u306b\u306f\u4f55\u304c\u3067\u304d\u3066\u4f55\u304c\u3067\u304d\u306a\u3044\u306e\u304b-17\">\u591a\u767a\u6027\u786c\u5316\u75c7\u306e\u75be\u60a3\u4fee\u98fe\u85ac\u306b\u306f\u4f55\u304c\u3067\u304d\u3066\u3001\u4f55\u304c\u3067\u304d\u306a\u3044\u306e\u304b<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-two-very-different-stem-cell-approaches-for-multiple-sclerosis-23\">\u591a\u767a\u6027\u786c\u5316\u75c7\u306b\u5bfe\u3059\u308b2\u3064\u306e\u7570\u306a\u308b\u5e79\u7d30\u80de\u30a2\u30d7\u30ed\u30fc\u30c1<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-how-mesenchymal-stem-cells-work-in-multiple-sclerosis-three-mechanisms-34\">\u591a\u767a\u6027\u786c\u5316\u75c7\u3067\u9593\u8449\u7cfb\u5e79\u7d30\u80de\u304c\u50cd\u304f3\u3064\u306e\u30e1\u30ab\u30cb\u30ba\u30e0<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u591a\u767a\u6027\u786c\u5316\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u3067\u81e8\u5e8a\u8a66\u9a13\u304c\u5b9f\u969b\u306b\u793a\u3057\u305f\u3053\u3068-60\">\u591a\u767a\u6027\u786c\u5316\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u3067\u81e8\u5e8a\u8a66\u9a13\u304c\u5b9f\u969b\u306b\u793a\u3057\u305f\u3053\u3068<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u591a\u767a\u6027\u786c\u5316\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u304c\u5411\u3044\u3066\u3044\u308b\u65b9\u5411\u3044\u3066\u3044\u306a\u3044\u65b9-77\">\u591a\u767a\u6027\u786c\u5316\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u304c\u5411\u3044\u3066\u3044\u308b\u65b9\u30fb\u5411\u3044\u3066\u3044\u306a\u3044\u65b9<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u591a\u767a\u6027\u786c\u5316\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u3092\u53d7\u3051\u305f\u60a3\u8005\u3055\u3093\u306e1\u5e74\u306e\u7d4c\u904e-90\">\u591a\u767a\u6027\u786c\u5316\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u3092\u53d7\u3051\u305f\u60a3\u8005\u3055\u3093\u306e1\u5e74\u306e\u7d4c\u904e<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u591a\u767a\u6027\u786c\u5316\u75c7\u5e79\u7d30\u80de\u6cbb\u7642\u306e\u30ea\u30b9\u30af\u3068\u9650\u754c-112\">\u591a\u767a\u6027\u786c\u5316\u75c7\u5e79\u7d30\u80de\u6cbb\u7642\u306e\u30ea\u30b9\u30af\u3068\u9650\u754c<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-faq-about-multiple-sclerosis-stem-cell-therapy-105\">\u591a\u767a\u6027\u786c\u5316\u75c7\u5e79\u7d30\u80de\u7642\u6cd5\u306b\u95a2\u3059\u308b\u3088\u304f\u3042\u308b\u8cea\u554f<\/a><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-a-conversation-about-your-specific-multiple-sclerosis-case-127\">\u3054\u81ea\u8eab\u306e\u30b1\u30fc\u30b9\u306b\u3064\u3044\u3066\u306e\u3054\u76f8\u8ac7<\/a><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-references-130\">\u53c2\u8003\u6587\u732e<\/a><\/li><\/ol><\/div>\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-why-multiple-sclerosis-continues-to-progress-even-on-treatment-6\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u591a\u767a\u6027\u786c\u5316\u75c7\u306f\u306a\u305cDMT\u3092\u4f7f\u3063\u3066\u3082\u9032\u884c\u3059\u308b\u3053\u3068\u304c\u3042\u308b\u306e\u304b<\/mark><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-the-autoimmune-damage-cycle-in-multiple-sclerosis-7\">\u81ea\u5df1\u514d\u75ab\u306e\u300c\u8aa4\u4f5c\u52d5\u300d\u304c\u591a\u767a\u6027\u786c\u5316\u75c7\u306e\u6838\u306b\u3042\u308a\u307e\u3059<\/h3>\n\n\n\n<p 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class=\"wp-element-caption\">HSCT\u3068MSC\u7642\u6cd5\u306f\u3057\u3070\u3057\u3070\u540c\u3058\u300c\u5e79\u7d30\u80de\u6cbb\u7642\u300d\u3068\u3057\u3066\u8a9e\u3089\u308c\u307e\u3059\u304c\u3001\u751f\u7269\u5b66\u7684\u306b\u3082\u624b\u9806\u7684\u306b\u3082\u307e\u3063\u305f\u304f\u7570\u306a\u308b\u30a2\u30d7\u30ed\u30fc\u30c1\u3067\u3059\u3002<\/figcaption><\/figure>\n<\/div>\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-hsct-for-multiple-sclerosis-powerful-but-aggressive-24\">\u591a\u767a\u6027\u786c\u5316\u75c7\u306eHSCT\uff1a\u5f37\u529b\u3060\u304c\u4fb5\u8972\u7684\u306a\u30a2\u30d7\u30ed\u30fc\u30c1<\/h3>\n\n\n\n<p 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class=\"wp-block-paragraph\">MSC\u306e\u30b7\u30b0\u30ca\u30eb\u306f\u3001\u30df\u30af\u30ed\u30b0\u30ea\u30a2\u3092\u708e\u75c7\u4fc3\u9032\u578b\u304b\u3089\u7d44\u7e54\u4fee\u5fa9\u30fb\u30b5\u30dd\u30fc\u30c8\u578b\u3078\u3068\u30b7\u30d5\u30c8\u3055\u305b\u308b\u4f5c\u7528\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u50cd\u304d\u306f\u3001\u6025\u6027\u306e\u518d\u767a\u3088\u308a\u3082\u300c\u518d\u767a\u306e\u306a\u3044\u9032\u884c\u300d\u304c\u4e3b\u5f79\u306b\u306a\u308b\u9032\u884c\u578bMS\u306b\u3068\u3063\u3066\u3001\u7279\u306b\u610f\u5473\u306e\u3042\u308b\u4f5c\u7528\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002\u6162\u6027\u708e\u75c7\u304c\u75c5\u614b\u9032\u884c\u306b\u95a2\u4e0e\u3059\u308b\u70b9\u3067\u306f\u3001\u5fc3\u4e0d\u5168\u306e\u9818\u57df\u3067\u3082\u985e\u4f3c\u306eMSC\u306e\u52b9\u679c\u304c\u7814\u7a76\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u672b\u68a2\u3067\u306e\u514d\u75ab\u8abf\u6574\u3001\u5c40\u6240\u3067\u306e\u795e\u7d4c\u4fdd\u8b77\u30b7\u30b0\u30ca\u30eb\u3001\u4e2d\u67a2\u306e\u6162\u6027\u708e\u75c7\u306e\u93ae\u9759\u3002\u3053\u306e3\u3064\u3092\u5408\u308f\u305b\u305f\u3082\u306e\u304c\u3001MSC\u6cbb\u7642\u304c\u591a\u767a\u6027\u786c\u5316\u75c7\u306e\u75be\u60a3\u4fee\u98fe\u7684\u4ecb\u5165\u306e\u5019\u88dc\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u308b\u751f\u7269\u5b66\u7684\u6839\u62e0\u3067\u3059\u3002\u554f\u984c\u306f\u3001\u81e8\u5e8a\u30c7\u30fc\u30bf\u304c\u5b9f\u969b\u306b\u3069\u3046\u793a\u3057\u3066\u3044\u308b\u304b\u3067\u3059\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-\u591a\u767a\u6027\u786c\u5316\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u3067\u81e8\u5e8a\u8a66\u9a13\u304c\u5b9f\u969b\u306b\u793a\u3057\u305f\u3053\u3068-60\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u591a\u767a\u6027\u786c\u5316\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u3067\u81e8\u5e8a\u8a66\u9a13\u304c\u5b9f\u969b\u306b\u793a\u3057\u305f\u3053\u3068<\/mark><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-mesems\u8a66\u9a13\u306f\u4f55\u3092\u793a\u3057\u4f55\u3092\u793a\u3055\u306a\u304b\u3063\u305f\u306e\u304b-61\">MESEMS\u8a66\u9a13\u306f\u4f55\u3092\u793a\u3057\u3001\u4f55\u3092\u793a\u3055\u306a\u304b\u3063\u305f\u306e\u304b<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u591a\u767a\u6027\u786c\u5316\u75c7\u306eMSC\u6cbb\u7642\u306b\u304a\u3051\u308b\u6700\u3082\u53b3\u683c\u306a\u81e8\u5e8a\u8a66\u9a13\u306f\u30012021\u5e74\u306bLancet Neurology\u8a8c\u3067\u767a\u8868\u3055\u308c\u305fMESEMS\u8a66\u9a13\uff08Uccelli \u3089\u306b\u3088\u308b\uff09\u3067\u3059\u3002\u3053\u306e\u8a66\u9a13\u306e\u8a71\u3092\u6700\u521d\u306b\u3059\u308b\u306e\u306f\u3001\u3053\u306e\u8a18\u4e8b\u3092\u8aad\u3093\u3067\u304f\u3060\u3055\u3063\u3066\u3044\u308b\u65b9\u304c\u771f\u5263\u306b\u3053\u306e\u5206\u91ce\u3092\u8abf\u3079\u308b\u4ee5\u4e0a\u3001\u77e5\u3063\u3066\u304a\u304f\u5fc5\u8981\u304c\u3042\u308b\u304b\u3089\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">MESEMS\u8a66\u9a13\u306f\u30019\u304b\u56fd15\u65bd\u8a2d\u3067144\u540d\u306eMS\u60a3\u8005\u3055\u3093\u3092\u5bfe\u8c61\u306b\u884c\u308f\u308c\u307e\u3057\u305f\u3002\u518d\u767a\u5bdb\u89e3\u578b\u3001\u4e8c\u6b21\u6027\u9032\u884c\u578b\u3001\u4e00\u6b21\u6027\u9032\u884c\u578b\u306e\u3044\u305a\u308c\u304b\u3067\u3001\u65e2\u5b58\u306e\u6cbb\u7642\u4e0b\u3067\u3082\u75be\u60a3\u6d3b\u52d5\u6027\u304c\u898b\u3089\u308c\u308b\u65b9\u304c\u5bfe\u8c61\u3067\u3059\u3002\u30c7\u30b6\u30a4\u30f3\u306f\u7121\u4f5c\u70ba\u5316\u3001\u4e8c\u91cd\u76f2\u691c\u3001\u30d7\u30e9\u30bb\u30dc\u5bfe\u7167\u3001\u30af\u30ed\u30b9\u30aa\u30fc\u30d0\u30fc\u578b\u3068\u3044\u3046\u3001\u30d5\u30a7\u30fc\u30ba2\u8a66\u9a13\u3068\u3057\u3066\u6975\u3081\u3066\u53b3\u683c\u306a\u8a2d\u8a08\u3067\u3057\u305f\u3002\u6295\u4e0e\u3055\u308c\u305f\u306e\u306f\u60a3\u8005\u3055\u3093\u81ea\u8eab\u306e\u9aa8\u9ac4\u304b\u3089\u63a1\u53d6\u3057\u305f\u81ea\u5bb6\u9aa8\u9ac4\u7531\u6765MSC\u3067\u3001\u7528\u91cf\u306f\u4f53\u91cd1kg\u3042\u305f\u308a100\u301c200\u4e07\u7d30\u80de\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u306fMRI\u3067\u306e\u9020\u5f71\u75c5\u5909\u306e\u6570\uff08\u3064\u307e\u308a\u6d3b\u52d5\u6027\u708e\u75c7\u306e\u6307\u6a19\uff09\u300124\u9031\u6642\u70b9\u3067\u306e\u8a55\u4fa1\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7d50\u679c\u3092\u6b63\u76f4\u306b\u66f8\u304d\u307e\u3059\u3002\u81ea\u5bb6\u9aa8\u9ac4MSC\u6cbb\u7642\u306f\u3001\u30d7\u30e9\u30bb\u30dc\u3068\u6bd4\u8f03\u3057\u3066\u9020\u5f71\u75c5\u5909\u306e\u6570\u3092\u6e1b\u3089\u3057\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u4e3b\u8981\u8a55\u4fa1\u9805\u76ee\u306f\u9054\u6210\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u5b89\u5168\u6027\u306f\u826f\u597d\u3067\u3001\u91cd\u5927\u306a\u6709\u5bb3\u4e8b\u8c61\u3084\u514d\u75ab\u62d2\u7d76\u53cd\u5fdc\u306f\u5831\u544a\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u304c\u3001\u6d3b\u52d5\u6027MS\u306b\u304a\u3044\u3066\u81ea\u5bb6\u9aa8\u9ac4MSC\u6cbb\u7642\u304c\u708e\u75c7\u6d3b\u52d5\u3092\u6291\u3048\u308b\u3068\u3044\u3046\u30a8\u30d3\u30c7\u30f3\u30b9\u306f\u3001\u3053\u306e\u8a66\u9a13\u3067\u306f\u5f97\u3089\u308c\u306a\u304b\u3063\u305f\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u306f\u91cd\u8981\u306a\u7d50\u679c\u3067\u3001\u60a3\u8005\u3055\u3093\u306b\u5bfe\u3057\u3066\u900f\u660e\u6027\u3092\u4fdd\u3064\u305f\u3081\u306b\u7701\u7565\u3057\u3066\u306f\u3044\u3051\u306a\u3044\u60c5\u5831\u3060\u3068\u79c1\u305f\u3061\u306f\u8003\u3048\u3066\u3044\u307e\u3059\u3002MESEMS\u306f\u73fe\u5b9f\u306e\u7d50\u679c\u3067\u3042\u308a\u3001MSC\u6cbb\u7642\u306b\u3064\u3044\u3066\u8a9e\u308c\u308b\u7bc4\u56f2\u3092\u5236\u7d04\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-\u4ed6\u5bb6\u81cd\u5e2f\u7531\u6765mscuc-msc\u306e\u81e8\u5e8a\u8a66\u9a13\u30c7\u30fc\u30bf-67\">\u4ed6\u5bb6\u81cd\u5e2f\u7531\u6765MSC\uff08UC-MSC\uff09\u306e\u81e8\u5e8a\u8a66\u9a13\u30c7\u30fc\u30bf<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3067\u3001\u79c1\u305f\u3061\u304c\u4f7f\u7528\u3057\u3066\u3044\u308b\u4ed6\u5bb6\u81cd\u5e2f\u7531\u6765MSC\u306b\u7279\u5316\u3057\u305f\u5c0f\u898f\u6a21\u306a\u8a66\u9a13\u3082\u3044\u304f\u3064\u304b\u767a\u8868\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6700\u3082\u3088\u304f\u5f15\u7528\u3055\u308c\u308b\u306e\u304c\u3001Riordan \u3089\uff08Journal of Translational Medicine, 2018\uff09\u306b\u3088\u308b20\u540d\u306eMS\u60a3\u8005\u3055\u3093\u3092\u5bfe\u8c61\u3068\u3057\u305f\u5b9f\u73fe\u53ef\u80fd\u6027\u8a66\u9a13\u3067\u3059\u3002\u60a3\u8005\u3055\u3093\u306f7\u65e5\u9593\u306b\u308f\u305f\u3063\u3066\u300120\u00d710\u2076\u7d30\u80de\u306eUC-MSC\u30927\u56de\u70b9\u6ef4\u6295\u4e0e\u3055\u308c\u307e\u3057\u305f\u3002\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u30011\u304b\u6708\u5f8c\u30011\u5e74\u5f8c\u306b\u8a55\u4fa1\u304c\u884c\u308f\u308c\u3001EDSS\uff08\u969c\u5bb3\u5ea6\u30b9\u30b3\u30a2\uff09\u3001Scripps\u795e\u7d4c\u5b66\u7684\u8a55\u4fa1\u30b9\u30b1\u30fc\u30eb\u30019\u7a74\u30da\u30b0\u30c6\u30b9\u30c8\uff08\u624b\u6307\u306e\u7d30\u304b\u3044\u904b\u52d5\u6a5f\u80fd\uff09\u300125\u30d5\u30a3\u30fc\u30c8\u6b69\u884c\u30c6\u30b9\u30c8\u3001RAND SF-36\uff08\u751f\u6d3b\u306e\u8cea\uff09\u3059\u3079\u3066\u306e\u6307\u6a19\u3067\u6539\u5584\u304c\u5831\u544a\u3055\u308c\u307e\u3057\u305f\u3002\u91cd\u5927\u306a\u6709\u5bb3\u4e8b\u8c61\u306f\u306a\u304f\u3001\u8efd\u5ea6\u306e\u526f\u4f5c\u7528\u306f\u982d\u75db\u3068\u75b2\u52b4\u304c\u4e2d\u5fc3\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3088\u308a\u65b0\u3057\u3044\u8a66\u9a13\u3067\u306f\u3001Shokati \u3089\uff08Scientific Reports, 2025\uff09\u304c\u4e8c\u6b21\u6027\u9032\u884c\u578bMS\u306e5\u540d\u3092\u5bfe\u8c61\u306b\u3001\u80ce\u76e4\u7531\u6765MSC\u306e\u30d5\u30a7\u30fc\u30ba1\u8a66\u9a13\u3092\u884c\u3044\u3001\u5b89\u5168\u6027\u3068\u969c\u5bb3\u30b9\u30b3\u30a2\u306e\u5b89\u5b9a\u307e\u305f\u306f\u6539\u5584\u306e\u30b7\u30b0\u30ca\u30eb\u304c\u5831\u544a\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2025\u5e74\u306bMultiple Sclerosis and Related 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data-wp-class--is-open=\"state.isOpen\" data-wp-context=\"{ &quot;id&quot;: &quot;accordion-item-5&quot;, &quot;openByDefault&quot;: false }\" data-wp-init=\"callbacks.initAccordionItems\" data-wp-on-window--hashchange=\"callbacks.hashChange\" class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h4 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-5-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" id=\"accordion-item-5\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span class=\"wp-block-accordion-heading__toggle-title\">\u6cbb\u7642\u306f\u4f55\u56de\u53d7\u3051\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u304b\uff1f<\/span><span class=\"wp-block-accordion-heading__toggle-icon\" aria-hidden=\"true\">+<\/span><\/button><\/h4>\n\n\n\n<div aria-labelledby=\"accordion-item-5\" data-wp-bind--hidden=\"state.isHidden\" 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id=\"aioseo-a-conversation-about-your-specific-multiple-sclerosis-case-127\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u3054\u81ea\u8eab\u306e\u30b1\u30fc\u30b9\u306b\u3064\u3044\u3066\u306e\u3054\u76f8\u8ac7<\/mark><\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u3053\u307e\u3067\u8aad\u3093\u3067\u304f\u3060\u3055\u3063\u305f\u65b9\u306f\u3001\u304a\u305d\u3089\u304f\u3059\u3067\u306b\u591a\u767a\u6027\u786c\u5316\u75c7\u3068\u66ae\u3089\u3057\u3001DMT\u3092\u7d99\u7d9a\u4e2d\u3067\u3001\u5316\u5b66\u7642\u6cd5\u3092\u4f34\u308f\u306a\u3044\u5e79\u7d30\u80de\u6cbb\u7642\u306b\u6b63\u76f4\u306b\u691c\u8a0e\u306e\u4f59\u5730\u304c\u3042\u308b\u306e\u304b\u3092\u77e5\u308a\u305f\u3044\u65b9\u3060\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p 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style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-references-130\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u53c2\u8003\u6587\u732e<\/mark><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Uccelli A, Laroni A, Ali R, et al. Safety, tolerability, and activity of mesenchymal stem cells versus placebo in multiple sclerosis (MESEMS): a phase 2, randomised, double-blind crossover trial. <em>Lancet Neurology<\/em>. 2021;20(11):917-929. <a href=\"https:\/\/doi.org\/10.1016\/S1474-4422(21)00301-X\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1016\/S1474-4422(21)00301-X<\/a><\/li>\n\n\n\n<li>Riordan NH, Morales I, Fern\u00e1ndez G, et al. Clinical feasibility of umbilical cord tissue-derived mesenchymal stem cells in the treatment of multiple sclerosis. <em>Journal of Translational Medicine<\/em>. 2018;16:57. <a href=\"https:\/\/doi.org\/10.1186\/s12967-018-1433-7\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1186\/s12967-018-1433-7<\/a><\/li>\n\n\n\n<li>Shokati A, Nikbakht M, Sahraian MA, et al. Cell therapy with placenta-derived mesenchymal stem cells for secondary progressive multiple sclerosis patients in a phase 1 clinical trial. <em>Scientific Reports<\/em>. 2025;15:16005. <a href=\"https:\/\/doi.org\/10.1038\/s41598-025-00590-6\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1038\/s41598-025-00590-6<\/a><\/li>\n\n\n\n<li>Walton C, King R, Rechtman L, et al. Rising prevalence of multiple sclerosis worldwide: Insights from the Atlas of MS, third edition. <em>Multiple Sclerosis Journal<\/em>. 2020;26(14):1816-1821. <a href=\"https:\/\/doi.org\/10.1177\/1352458520970841\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1177\/1352458520970841<\/a><\/li>\n\n\n\n<li>Sheikhi K, Ghaderi S, Firouzi H, et al. Recent advances in mesenchymal stem cell therapy for multiple sclerosis: clinical applications and challenges. <em>Frontiers in Cell and Developmental Biology<\/em>. 2025;13:1517369. <a href=\"https:\/\/doi.org\/10.3389\/fcell.2025.1517369\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.3389\/fcell.2025.1517369<\/a><\/li>\n\n\n\n<li>Muraro PA, Pasquini M, Atkins HL, et al. Long-term outcomes after autologous hematopoietic stem cell transplantation for multiple sclerosis. <em>JAMA Neurology<\/em>. 2017;74(4):459-469. <a href=\"https:\/\/doi.org\/10.1001\/jamaneurol.2016.5867\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1001\/jamaneurol.2016.5867<\/a><\/li>\n\n\n\n<li>Sormani MP, Muraro PA, Schiavetti I, et al. Autologous hematopoietic stem cell transplantation in multiple sclerosis. <em>Neurology<\/em>. 2017;88(22):2115-2122. <a href=\"https:\/\/doi.org\/10.1212\/WNL.0000000000003987\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1212\/WNL.0000000000003987<\/a><\/li>\n\n\n\n<li>Cohen JA, Imrey PB, Planchon SM, et al. Pilot trial of intravenous autologous culture-expanded mesenchymal stem cell transplantation in multiple sclerosis. <em>Multiple Sclerosis Journal<\/em>. 2018;24(4):501-511. <a href=\"https:\/\/doi.org\/10.1177\/1352458517703802\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1177\/1352458517703802<\/a><\/li>\n\n\n\n<li>Mesenchymal stem cells in clinical trials for multiple sclerosis: A systematic literature review and review of clinical trials. <em>Multiple Sclerosis and Related Disorders<\/em>. 2025. <a href=\"https:\/\/doi.org\/10.1016\/j.msard.2025.106492\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1016\/j.msard.2025.106492<\/a><\/li>\n\n\n\n<li>GBD 2021 Epidemiology of Multiple Sclerosis Collaborators. Epidemiology of Multiple Sclerosis: Global, Regional, National and Sub-National-Level Estimates and Future Projections. <em>Journal of Epidemiology and Global Health<\/em>. 2025. <a href=\"https:\/\/doi.org\/10.1007\/s44197-025-00353-6\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1007\/s44197-025-00353-6<\/a><\/li>\n<\/ol>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\t\t<div data-elementor-type=\"section\" data-elementor-id=\"21873\" class=\"elementor elementor-21873\" data-elementor-post-type=\"elementor_library\">\n\t\t\t        <section class=\"elementor-section elementor-top-section elementor-element elementor-element-a6ebaad elementor-section-boxed elementor-section-height-default elementor-section-height-default pxl-row-scroll-none pxl-zoom-point-false pxl-section-overflow-visible pxl-section-fix-none pxl-bg-color-none pxl-section-overlay-none\" data-id=\"a6ebaad\" data-element_type=\"section\" 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