{"id":25079,"date":"2026-05-11T14:49:45","date_gmt":"2026-05-11T06:49:45","guid":{"rendered":"https:\/\/stemcell-malaysia.com\/?page_id=25079"},"modified":"2026-05-11T14:49:47","modified_gmt":"2026-05-11T06:49:47","slug":"pulmonary-fibrosis","status":"publish","type":"page","link":"https:\/\/stemcell-malaysia.com\/ja\/conditions\/pulmonary-fibrosis\/","title":{"rendered":"\u80ba\u7dda\u7dad\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\uff5c\u80ba\u79fb\u690d\u305b\u305a\u306b\u9032\u884c\u3092\u9045\u3089\u305b\u308b\u9078\u629e\u80a2\u306f\u3042\u308b\u304b"},"content":{"rendered":"\n<h1 class=\"wp-block-heading\">\u80ba\u7dda\u7dad\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\uff5c\u80ba\u79fb\u690d\u305b\u305a\u306b\u9032\u884c\u3092\u9045\u3089\u305b\u308b\u9078\u629e\u80a2\u306f\u3042\u308b\u304b<\/h1>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"440\" 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class=\"wp-block-heading\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u76ee\u6b21<\/mark><\/h2>\n\n\n<div class=\"wp-block-aioseo-table-of-contents\"><ol><li><a class=\"aioseo-toc-item\" href=\"#aioseo-why-pulmonary-fibrosis-cannot-heal-through-natural-repair-9\">\u306a\u305c\u80ba\u7dda\u7dad\u75c7\u306f\u81ea\u7136\u306b\u6cbb\u3089\u306a\u3044\u306e\u304b<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u6297\u7dda\u7dad\u5316\u85ac\u3067\u5230\u9054\u3059\u308b\u5929\u4e95-19\">\u6297\u7dda\u7dad\u5316\u85ac\u3067\u5230\u9054\u3059\u308b\u5929\u4e95<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u80ba\u79fb\u690d\u304c\u9078\u629e\u80a2\u306b\u306a\u308a\u306b\u304f\u3044\u73fe\u5b9f-27\">\u80ba\u79fb\u690d\u304c\u9078\u629e\u80a2\u306b\u306a\u308a\u306b\u304f\u3044\u73fe\u5b9f<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-how-stem-cells-approach-pulmonary-fibrosis-at-the-tissue-level-41\">\u80ba\u7dda\u7dad\u75c7\u306b\u5bfe\u3059\u308b\u5e79\u7d30\u80de\u306e3\u3064\u306e\u4f5c\u7528<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-what-published-pulmonary-fibrosis-stem-cell-trials-have-actually-shown-54\">\u80ba\u7dda\u7dad\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u3067\u767a\u8868\u3055\u308c\u3066\u3044\u308b\u81e8\u5e8a\u30c7\u30fc\u30bf<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u4ed6\u5bb6\u81cd\u5e2f\u7531\u6765msc\u3092\u4f7f\u3046\u7406\u7531-76\">\u4ed6\u5bb6\u81cd\u5e2f\u7531\u6765MSC\u3092\u4f7f\u3046\u7406\u7531<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u80ba\u7dda\u7dad\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u304c\u5411\u3044\u3066\u3044\u308b\u65b9\u5411\u3044\u3066\u3044\u306a\u3044\u65b9-86\">\u80ba\u7dda\u7dad\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u304c\u5411\u3044\u3066\u3044\u308b\u65b9\u30fb\u5411\u3044\u3066\u3044\u306a\u3044\u65b9<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u5e79\u7d30\u80de\u6cbb\u7642\u3092\u53d7\u3051\u305f\u80ba\u7dda\u7dad\u75c7\u60a3\u8005\u306e12\u30f6\u6708\u306e\u7d4c\u904e-95\">\u5e79\u7d30\u80de\u6cbb\u7642\u3092\u53d7\u3051\u305f\u80ba\u7dda\u7dad\u75c7\u60a3\u8005\u306e12\u30f6\u6708\u306e\u7d4c\u904e<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u6b63\u76f4\u306a\u30ea\u30b9\u30af\u3068\u3067\u304d\u306a\u3044\u3053\u3068-104\">\u6b63\u76f4\u306a\u30ea\u30b9\u30af\u3068\u3001\u3067\u304d\u306a\u3044\u3053\u3068<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-faq-about-pulmonary-fibrosis-stem-cell-therapy-125\">\u80ba\u7dda\u7dad\u75c7\u5e79\u7d30\u80de\u7642\u6cd5\u306b\u95a2\u3059\u308b\u3088\u304f\u3042\u308b\u8cea\u554f<\/a><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-if-youre-considering-pulmonary-fibrosis-stem-cell-therapy-152\">\u6b21\u306e\u4e00\u6b69<\/a><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-references-156\">\u53c2\u8003\u6587\u732e<\/a><\/li><\/ol><\/div>\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-why-pulmonary-fibrosis-cannot-heal-through-natural-repair-9\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u306a\u305c\u80ba\u7dda\u7dad\u75c7\u306f\u81ea\u7136\u306b\u6cbb\u3089\u306a\u3044\u306e\u304b<\/mark><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-how-alveolar-damage-triggers-the-scarring-process-in-pulmonary-fibrosis-10\">\u80ba\u80de\u306e\u640d\u50b7\u304b\u3089\u59cb\u307e\u308b\u7dda\u7dad\u5316\u306e\u30d7\u30ed\u30bb\u30b9<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u80ba\u306e\u5965\u306b\u306f\u3001\u80ba\u80de\u3068\u547c\u3070\u308c\u308b\u5c0f\u3055\u306a\u98a8\u8239\u306e\u3088\u3046\u306a\u90e8\u5c4b\u304c\u7247\u80ba\u306b\u7d043\u5104\u500b\u4e26\u3093\u3067\u3044\u307e\u3059\u3002\u80ba\u80de\u306e\u58c1\u306f\u975e\u5e38\u306b\u8584\u304f\u3001\u3053\u3053\u3067\u5438\u3044\u8fbc\u3093\u3060\u7a7a\u6c17\u306e\u4e2d\u306e\u9178\u7d20\u304c\u8840\u6db2\u306b\u53d6\u308a\u8fbc\u307e\u308c\u3001\u4e8c\u9178\u5316\u70ad\u7d20\u304c\u6392\u51fa\u3055\u308c\u307e\u3059\u3002\u80ba\u80de\u306e\u7dcf\u8868\u9762\u7a4d\u306f\u30c6\u30cb\u30b9\u30b3\u30fc\u30c8\u4e00\u9762\u5206\u306b\u3082\u76f8\u5f53\u3059\u308b\u3068\u3044\u308f\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p 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style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-\u7dda\u7dad\u5316\u304c\u6b62\u307e\u3089\u305a\u5e83\u304c\u3063\u3066\u3044\u304f\u4ed5\u7d44\u307f-16\">\u7dda\u7dad\u5316\u304c\u6b62\u307e\u3089\u305a\u5e83\u304c\u3063\u3066\u3044\u304f\u4ed5\u7d44\u307f<\/h3>\n\n\n\n<p 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id=\"aioseo-\u6297\u7dda\u7dad\u5316\u85ac\u3067\u5230\u9054\u3059\u308b\u5929\u4e95-19\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u6297\u7dda\u7dad\u5316\u85ac\u3067\u5230\u9054\u3059\u308b\u5929\u4e95<\/mark><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-\u30d4\u30eb\u30d5\u30a7\u30cb\u30c9\u30f3\u3068\u30cb\u30f3\u30c6\u30c0\u30cb\u30d6\u304c\u3067\u304d\u308b\u3053\u3068-20\">\u30d4\u30eb\u30d5\u30a7\u30cb\u30c9\u30f3\u3068\u30cb\u30f3\u30c6\u30c0\u30cb\u30d6\u304c\u3067\u304d\u308b\u3053\u3068<\/h3>\n\n\n\n<p 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id=\"aioseo-\u526f\u4f5c\u7528\u3067\u85ac\u304c\u7d9a\u3051\u3089\u308c\u306a\u304f\u306a\u308b\u73fe\u5b9f-24\">\u526f\u4f5c\u7528\u3067\u85ac\u304c\u7d9a\u3051\u3089\u308c\u306a\u304f\u306a\u308b\u73fe\u5b9f<\/h3>\n\n\n\n<p 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class=\"has-inline-color\">\u80ba\u7dda\u7dad\u75c7\u306b\u5bfe\u3059\u308b\u5e79\u7d30\u80de\u306e3\u3064\u306e\u4f5c\u7528<\/mark><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"800\" height=\"518\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-1.webp\" alt=\"\u80ba\u7dda\u7dad\u75c7\u306b\u5bfe\u3059\u308b\u9593\u8449\u7cfb\u5e79\u7d30\u80de\u306e3\u3064\u306e\u4f5c\u7528\uff08\u514d\u75ab\u8abf\u6574\u3001\u6297\u7dda\u7dad\u5316\u30b7\u30b0\u30ca\u30eb\u3001\u80ba\u80de\u4e0a\u76ae\u306e\u4fdd\u8b77\uff09\u3092\u793a\u3057\u305f\u56f3\u89e3\" class=\"wp-image-25081\" style=\"aspect-ratio:1.5384958986437098;width:512px;height:auto\" srcset=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-1.webp 800w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-1-300x194.webp 300w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-1-768x497.webp 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption class=\"wp-element-caption\">\u9593\u8449\u7cfb\u5e79\u7d30\u80de\u306f3\u3064\u306e\u9593\u63a5\u7684\u306a\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u901a\u3058\u3066\u80ba\u7dda\u7dad\u75c7\u306e\u9032\u884c\u306b\u50cd\u304d\u304b\u3051\u307e\u3059\u3002\u3059\u3067\u306b\u7dda\u7dad\u5316\u3057\u305f\u7d44\u7e54\u3092\u518d\u751f\u3059\u308b\u308f\u3051\u3067\u306f\u306a\u304f\u3001\u3053\u308c\u4ee5\u4e0a\u306e\u640d\u50b7\u3092\u9045\u3089\u305b\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u305f\u4f5c\u7528\u3067\u3059\u3002<\/figcaption><\/figure>\n<\/div>\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-three-biological-mechanisms-behind-stem-cell-therapy-for-pulmonary-fibrosis-43\">\u5e79\u7d30\u80de\u306f\u65b0\u3057\u3044\u80ba\u7d44\u7e54\u306b\u300c\u5909\u8eab\u300d\u3057\u306a\u3044<\/h3>\n\n\n\n<p 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class=\"wp-block-paragraph\">\u7b4b\u7dda\u7dad\u82bd\u7d30\u80de\u306f\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u3092\u5927\u91cf\u306b\u4f5c\u308a\u51fa\u3057\u3066\u7622\u75d5\u7d44\u7e54\u3092\u5e83\u3052\u308b\u300c\u4e3b\u72af\u683c\u300d\u306e\u7d30\u80de\u3067\u3059\u3002MSC\u306f\u3053\u306e\u5909\u5316\u306e\u30b9\u30a4\u30c3\u30c1\u3092\u6291\u3048\u308b\u3053\u3068\u3067\u3001\u80ba\u7dda\u7dad\u75c7\u306e\u9032\u884c\u306b\u76f4\u63a5\u7684\u306b\u30d6\u30ec\u30fc\u30ad\u3092\u304b\u3051\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-\u4f5c\u75283\u6b8b\u3063\u3066\u3044\u308b\u80ba\u80de\u4e0a\u76ae\u7d30\u80de\u3092\u652f\u3048\u308b-54\">\u4f5c\u75283\uff1a\u6b8b\u3063\u3066\u3044\u308b\u80ba\u80de\u4e0a\u76ae\u7d30\u80de\u3092\u652f\u3048\u308b<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">3\u3064\u76ee\u306f\u3001\u30c0\u30e1\u30fc\u30b8\u3092\u53d7\u3051\u306a\u304c\u3089\u3082\u307e\u3060\u751f\u304d\u3066\u3044\u308b\u80ba\u80de\u4e0a\u76ae\u7d30\u80de\u3092\u652f\u3048\u308b\u4f5c\u7528\u3067\u3059\u3002MSC\u306f\u3001\u7d30\u80de\u306e\u751f\u5b58\u3092\u52a9\u3051\u308b\u5404\u7a2e\u306e\u6210\u9577\u56e0\u5b50\u3092\u5206\u6ccc\u3057\u3001\u80ba\u80de\u306e\u30d0\u30ea\u30a2\u6a5f\u80fd\u3092\u7dad\u6301\u3059\u308b\u306e\u3092\u52a9\u3051\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u306f\u3001\u5fc3\u81d3\u306e\u30dd\u30f3\u30d7\u6a5f\u80fd\u304c\u843d\u3061\u3066\u3044\u3066\u3082\u6b8b\u5b58\u3057\u3066\u3044\u308b\u5fc3\u7b4b\u7d30\u80de\u3092\u652f\u3048\u308b\u5fc3\u4e0d\u5168\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u306e\u8003\u3048\u65b9\u3068\u3082\u5171\u901a\u3057\u3066\u3044\u307e\u3059\u3002\u5931\u308f\u308c\u305f\u7d44\u7e54\u3092\u4f5c\u308a\u76f4\u3059\u306e\u3067\u306f\u306a\u304f\u3001\u6b8b\u3063\u3066\u3044\u308b\u7d44\u7e54\u304c\u9577\u304f\u6a5f\u80fd\u3057\u7d9a\u3051\u3089\u308c\u308b\u74b0\u5883\u3092\u6574\u3048\u308b\u3001\u3068\u3044\u3046\u30a2\u30d7\u30ed\u30fc\u30c1\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u3089\u306e\u4f5c\u7528\u306f\u3001\u3059\u3067\u306b\u5b8c\u6210\u3057\u3066\u3057\u307e\u3063\u305f\u7622\u75d5\u7d44\u7e54\u3092\u6d88\u3059\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u7dda\u7dad\u5316\u304c\u5e83\u304c\u308b\u300c\u901f\u5ea6\u300d\u3092\u6291\u3048\u3001\u6b8b\u3063\u3066\u3044\u308b\u80ba\u6a5f\u80fd\u3092\u9577\u304f\u4fdd\u3064\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u305f\u50cd\u304d\u304b\u3051\u3067\u3059\u3002\u79c1\u305f\u3061\u306f\u3053\u306e\u70b9\u3092\u3001\u6cbb\u7642\u524d\u306e\u3054\u76f8\u8ac7\u3067\u5fc5\u305a\u6b63\u76f4\u306b\u304a\u4f1d\u3048\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-what-published-pulmonary-fibrosis-stem-cell-trials-have-actually-shown-54\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u80ba\u7dda\u7dad\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u3067\u767a\u8868\u3055\u308c\u3066\u3044\u308b\u81e8\u5e8a\u30c7\u30fc\u30bf<\/mark><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"800\" height=\"436\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/MSC\u6cbb\u7642\u7fa4.webp\" alt=\"\u80ba\u7dda\u7dad\u75c7\u60a3\u8005\u306b\u304a\u3051\u308b\u9ad8\u7528\u91cf\u9593\u8449\u7cfb\u5e79\u7d30\u80de\u6cbb\u7642\u7fa4\u3068\u30d7\u30e9\u30bb\u30dc\u7fa4\u306e\u80ba\u6d3b\u91cf\uff08FVC\uff09\u5909\u5316\u3092\u6bd4\u8f03\u3057\u305f\u30b0\u30e9\u30d5\uff08Averyanov 2020\u5e74\u30c7\u30fc\u30bf\uff09\" class=\"wp-image-25083\" style=\"width:592px\" srcset=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/MSC\u6cbb\u7642\u7fa4.webp 800w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/MSC\u6cbb\u7642\u7fa4-300x164.webp 300w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/MSC\u6cbb\u7642\u7fa4-768x419.webp 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption class=\"wp-element-caption\">Averyanov 2020\u5e74\uff08Stem Cells Translational Medicine\u8a8c\uff09\u306e\u81e8\u5e8a\u8a66\u9a13\u3067\u306f\u3001\u9ad8\u7d2f\u7a4d\u7528\u91cf\u306e\u4ed6\u5bb6MSC\u3092\u6295\u4e0e\u3055\u308c\u305f\u6025\u901f\u9032\u884c\u578b\u80ba\u7dda\u7dad\u75c7\u60a3\u8005\u7fa4\u3067FVC\u304c\u6539\u5584\u3057\u3001\u30d7\u30e9\u30bb\u30dc\u7fa4\u3067\u306f\u4f4e\u4e0b\u304c\u7d9a\u304d\u307e\u3057\u305f\u3002<\/figcaption><\/figure>\n<\/div>\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-key-clinical-trials-on-stem-cell-therapy-for-pulmonary-fibrosis-57\">\u4e3b\u8981\u306a\u80ba\u7dda\u7dad\u75c7\u81e8\u5e8a\u8a66\u9a13\u3068\u305d\u306e\u7d50\u679c<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u80ba\u7dda\u7dad\u75c7\u306b\u5bfe\u3059\u308b\u5e79\u7d30\u80de\u6cbb\u7642\u306e\u81e8\u5e8a\u8a66\u9a13\u30c7\u30fc\u30bf\u306f\u3001\u5fc3\u81d3\u9818\u57df\u306b\u6bd4\u3079\u308b\u3068\u307e\u3060\u82e5\u3044\u5206\u91ce\u3067\u3059\u304c\u3001\u3044\u304f\u3064\u304b\u306e\u7b2cI\u76f8\u30fb\u7b2cII\u76f8\u8a66\u9a13\u304c\u5b8c\u4e86\u3057\u3001\u67fb\u8aad\u4ed8\u304d\u306e\u533b\u5b66\u8a8c\u306b\u767a\u8868\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">AETHER\u8a66\u9a13\uff08Glassberg et al., Chest\u8a8c, 2017\u5e74\uff09\u306f\u3001\u7c73\u56fd\u3067\u5b9f\u65bd\u3055\u308c\u305f\u3001\u7279\u767a\u6027\u80ba\u7dda\u7dad\u75c7\u306b\u5bfe\u3059\u308b\u4ed6\u5bb6\u9aa8\u9ac4\u7531\u6765MSC\u306e\u5b89\u5168\u6027\u3092\u8a55\u4fa1\u3059\u308b\u6700\u521d\u306e\u8a66\u9a13\u3067\u3059\u3002\u8efd\u75c7\u301c\u4e2d\u7b49\u75c7\u306eIPF\u60a3\u80059\u540d\u304c\u30012,000\u4e07\u500b\u30011\u5104\u500b\u30012\u5104\u500b\u306e3\u3064\u306e\u7528\u91cf\u30671\u56de\u306e\u70b9\u6ef4\u3092\u53d7\u3051\u307e\u3057\u305f\u300260\u9031\u9593\u306e\u7d4c\u904e\u89b3\u5bdf\u671f\u9593\u4e2d\u3001\u5e79\u7d30\u80de\u6295\u4e0e\u306b\u8d77\u56e0\u3059\u308b\u91cd\u7be4\u306a\u526f\u4f5c\u7528\u306f\u78ba\u8a8d\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u30022\u540d\u306e\u65b9\u304c\u8a66\u9a13\u671f\u9593\u4e2d\u306b\u4ea1\u304f\u306a\u308a\u307e\u3057\u305f\u304c\u3001\u3044\u305a\u308c\u3082\u80ba\u7dda\u7dad\u75c7\u306e\u9032\u884c\u306b\u3088\u308b\u6b7b\u4ea1\u3067\u3042\u308a\u3001\u6cbb\u7642\u3068\u306e\u95a2\u9023\u306f\u306a\u3044\u3068\u5224\u65ad\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u8a66\u9a13\u306b\u3088\u308a\u3001\u4ed6\u5bb6MSC\u3092\u80ba\u7dda\u7dad\u75c7\u60a3\u8005\u306b\u9759\u8108\u5185\u6295\u4e0e\u3059\u308b\u3053\u3068\u304c\u3001\u73fe\u5b9f\u7684\u306b\u5b9f\u65bd\u53ef\u80fd\u3067\u5b89\u5168\u6027\u304c\u8a31\u5bb9\u7bc4\u56f2\u3067\u3042\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7279\u306b\u6ce8\u76ee\u306b\u5024\u3059\u308b\u306e\u304c\u3001Averyanov et al. \u306e\u8a66\u9a13\uff08Stem Cells Translational Medicine\u8a8c, 2020\u5e74\uff09\u3067\u3059\u3002\u6025\u901f\u306b\u9032\u884c\u3059\u308b\u80ba\u7dda\u7dad\u75c7\u60a3\u800520\u540d\u3092\u5bfe\u8c61\u306b\u3001\u9ad8\u7d2f\u7a4d\u7528\u91cf\uff08\u6700\u592720\u5104\u500b\uff09\u306e\u9aa8\u9ac4\u7531\u6765MSC\u3092\u8907\u6570\u56de\u6295\u4e0e\u3059\u308b\u7fa4\u3068\u3001\u30d7\u30e9\u30bb\u30dc\u7fa4\u3092\u6bd4\u8f03\u3057\u305f\u8a66\u9a13\u3067\u3059\u300252\u9031\u9593\u306e\u7d4c\u904e\u89b3\u5bdf\u3067\u3001MSC\u6295\u4e0e\u7fa4\u306fFVC\u304c\u6cbb\u7642\u671f\u9593\u4e2d\u306b\u4e0a\u6607\u3057\u305f\u306e\u306b\u5bfe\u3057\u3001\u30d7\u30e9\u30bb\u30dc\u7fa4\u306f\u4e88\u60f3\u901a\u308a\u306b\u4f4e\u4e0b\u3092\u7d9a\u3051\u307e\u3057\u305f\u30026\u5206\u9593\u6b69\u884c\u8ddd\u96e2\u3082MSC\u7fa4\u3067\u660e\u3089\u304b\u306b\u6539\u5584\u3057\u3001\u9178\u7d20\u62e1\u6563\u80fd\uff08DLCO\u3001\u9178\u7d20\u304c\u80ba\u80de\u304b\u3089\u8840\u6db2\u3078\u3069\u308c\u3060\u3051\u52b9\u7387\u3088\u304f\u79fb\u52d5\u3059\u308b\u304b\u306e\u6307\u6a19\uff09\u3082MSC\u7fa4\u3067\u3088\u308a\u826f\u597d\u306b\u4fdd\u305f\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Tzouvelekis et al. \u306e\u8a66\u9a13\uff08Journal of Translational Medicine\u8a8c, 2013\u5e74\uff09\u3067\u306f\u3001\u8102\u80aa\u7531\u6765\u306e\u5e79\u7d30\u80de\u3092\u6c17\u7ba1\u652f\u93e1\u3092\u7528\u3044\u3066\u80ba\u5185\u306b\u76f4\u63a5\u6295\u4e0e\u3059\u308b\u5225\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\u3067\u300114\u540d\u306eIPF\u60a3\u8005\u30926\u30f6\u6708\u9593\u8ffd\u8de1\u3057\u307e\u3057\u305f\u30026\u5206\u9593\u6b69\u884c\u8ddd\u96e2\u3068\u80ba\u6d3b\u91cf\u306b\u308f\u305a\u304b\u306a\u6539\u5584\u304c\u5831\u544a\u3055\u308c\u3001\u7d30\u80de\u7531\u6765\u306e\u91cd\u7be4\u306a\u526f\u4f5c\u7528\u306f\u8a8d\u3081\u3089\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-\u3053\u308c\u3089\u306e\u6570\u5b57\u3092\u6b63\u76f4\u306b\u8aad\u307f\u89e3\u304f-70\">\u3053\u308c\u3089\u306e\u6570\u5b57\u3092\u6b63\u76f4\u306b\u8aad\u307f\u89e3\u304f<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u3053\u3067\u3001\u3044\u304f\u3064\u304b\u306e\u70b9\u3092\u6b63\u76f4\u306b\u304a\u4f1d\u3048\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7b2c\u4e00\u306b\u3001\u3044\u305a\u308c\u306e\u8a66\u9a13\u3082\u898f\u6a21\u304c\u5c0f\u3055\u3044\u3067\u3059\u3002AETHER\u306f9\u540d\u3001Averyanov\u306f20\u540d\u3001Tzouvelekis\u306f14\u540d\u3067\u3059\u3002\u3053\u308c\u306f\u7b2cI\u76f8\u301c\u7b2cII\u76f8\u306e\u898f\u6a21\u3067\u3042\u308a\u3001\u6297\u7dda\u7dad\u5316\u85ac\u306e\u8a8d\u53ef\u8a66\u9a13\u306b\u7d44\u307e\u308c\u305f\u6570\u5343\u4eba\u898f\u6a21\u306e\u8a66\u9a13\u3068\u306f\u307e\u3060\u6bd4\u8f03\u3067\u304d\u308b\u6bb5\u968e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002Averyanov\u306e\u30d7\u30e9\u30bb\u30dc\u5bfe\u7167\u30c7\u30b6\u30a4\u30f3\u3067\u306e\u7d50\u679c\u306f\u5fc3\u5f37\u3044\u3082\u306e\u3067\u3059\u304c\u3001\u3088\u308a\u5927\u898f\u6a21\u306a\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u3067\u306e\u78ba\u8a8d\u306f\u307e\u3060\u3053\u308c\u304b\u3089\u3067\u3059\u3002<\/p>\n\n\n\n<p 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data-wp-context=\"{ &quot;autoclose&quot;: false, &quot;accordionItems&quot;: [] }\" data-wp-interactive=\"core\/accordion\" role=\"group\" class=\"wp-block-accordion is-layout-flow wp-block-accordion-is-layout-flow\">\n<div data-wp-class--is-open=\"state.isOpen\" data-wp-context=\"{ &quot;id&quot;: &quot;accordion-item-1&quot;, &quot;openByDefault&quot;: false }\" data-wp-init=\"callbacks.initAccordionItems\" data-wp-on-window--hashchange=\"callbacks.hashChange\" class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h4 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-1-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" id=\"accordion-item-1\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span 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data-wp-context=\"{ &quot;autoclose&quot;: false, &quot;accordionItems&quot;: [] }\" data-wp-interactive=\"core\/accordion\" role=\"group\" class=\"wp-block-accordion is-layout-flow wp-block-accordion-is-layout-flow\">\n<div data-wp-class--is-open=\"state.isOpen\" data-wp-context=\"{ &quot;id&quot;: &quot;accordion-item-3&quot;, &quot;openByDefault&quot;: false }\" data-wp-init=\"callbacks.initAccordionItems\" data-wp-on-window--hashchange=\"callbacks.hashChange\" class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h4 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-3-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" id=\"accordion-item-3\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span 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style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-references-156\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u53c2\u8003\u6587\u732e<\/mark><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Glassberg MK, Minkiewicz J, Toonkel RL, et al. &#8220;Allogeneic Human Mesenchymal Stem Cells in Patients With Idiopathic Pulmonary Fibrosis via Intravenous Delivery (AETHER): A Phase I Safety Clinical Trial.&#8221; Chest. 2017;151(5):971\u2013981. <a href=\"https:\/\/doi.org\/10.1016\/j.chest.2016.10.061\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1016\/j.chest.2016.10.061<\/a><\/li>\n\n\n\n<li>Averyanov A, Koroleva I, Konoplyannikov M, et al. &#8220;First-in-human high-cumulative-dose stem cell therapy in idiopathic pulmonary fibrosis with rapid lung function decline.&#8221; Stem Cells Translational Medicine. 2020;9(1):6\u201316. <a href=\"https:\/\/doi.org\/10.1002\/sctm.19-0037\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1002\/sctm.19-0037<\/a><\/li>\n\n\n\n<li>Tzouvelekis A, Paspaliaris V, Koliakos G, et al. &#8220;A prospective, non-randomized, no placebo-controlled, phase Ib clinical trial to study the safety of the adipose derived stromal cells-stromal vascular fraction in idiopathic pulmonary fibrosis.&#8221; Journal of Translational Medicine. 2013;11:171. <a href=\"https:\/\/doi.org\/10.1186\/1479-5876-11-171\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1186\/1479-5876-11-171<\/a><\/li>\n\n\n\n<li>Cheng W, Zeng Y, Wang D. &#8220;Stem cell-based therapy for pulmonary fibrosis.&#8221; Stem Cell Research &amp; Therapy. 2022;13:492. <a href=\"https:\/\/doi.org\/10.1186\/s13287-022-03181-8\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1186\/s13287-022-03181-8<\/a><\/li>\n\n\n\n<li>Maher TM, Bendstrup E, Dron L, et al. &#8220;Global incidence and prevalence of idiopathic pulmonary fibrosis.&#8221; Respiratory Research. 2021;22:197. <a href=\"https:\/\/doi.org\/10.1186\/s12931-021-01791-z\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1186\/s12931-021-01791-z<\/a><\/li>\n\n\n\n<li>Richeldi L, Collard HR, Jones MG. &#8220;Idiopathic pulmonary fibrosis.&#8221; Lancet. 2017;389(10082):1941\u20131952. <a href=\"https:\/\/doi.org\/10.1016\/S0140-6736(17)30866-8\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1016\/S0140-6736(17)30866-8<\/a><\/li>\n\n\n\n<li>Lederer DJ, Martinez FJ. &#8220;Idiopathic Pulmonary Fibrosis.&#8221; New England Journal of Medicine. 2018;378:1811\u20131823. <a href=\"https:\/\/doi.org\/10.1056\/NEJMra1705751\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1056\/NEJMra1705751<\/a><\/li>\n<\/ol>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\t\t<div data-elementor-type=\"section\" 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