{"id":24909,"date":"2026-05-05T12:24:56","date_gmt":"2026-05-05T04:24:56","guid":{"rendered":"https:\/\/stemcell-malaysia.com\/?page_id=24909"},"modified":"2026-05-05T12:24:58","modified_gmt":"2026-05-05T04:24:58","slug":"dementia","status":"publish","type":"page","link":"https:\/\/stemcell-malaysia.com\/ja\/conditions\/dementia\/","title":{"rendered":"\u8a8d\u77e5\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\uff5c\u85ac\u3067\u306f\u6b62\u307e\u3089\u306a\u3044\u9032\u884c\u3092\u672c\u5f53\u306b\u9045\u3089\u305b\u3089\u308c\u308b\u306e\u304b\u3001\u81e8\u5e8a\u30c7\u30fc\u30bf\u3067\u8003\u3048\u308b"},"content":{"rendered":"\n<h1 class=\"wp-block-heading has-text-align-center\">\u8a8d\u77e5\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\uff5c\u85ac\u3067\u306f\u6b62\u307e\u3089\u306a\u3044\u9032\u884c\u3092\u672c\u5f53\u306b\u9045\u3089\u305b\u3089\u308c\u308b\u306e\u304b\u3001\u81e8\u5e8a\u30c7\u30fc\u30bf\u3067\u8003\u3048\u308b<\/h1>\n\n\n<div class=\"wp-block-image\">\n<figure 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href=\"#aioseo-\u65e2\u5b58\u306e\u8a8d\u77e5\u75c7\u6cbb\u7642\u85ac\u306e\u672c\u5f53\u306e\u9650\u754c-24\">\u65e2\u5b58\u306e\u8a8d\u77e5\u75c7\u6cbb\u7642\u85ac\u306e\u672c\u5f53\u306e\u9650\u754c<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-three-mechanisms-how-stem-cells-may-influence-the-dementia-brain-30\">\u8a8d\u77e5\u75c7\u306b\u5bfe\u3059\u308b\u5e79\u7d30\u80de\u6cbb\u7642\u306e3\u3064\u306e\u4f5c\u7528<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u8840\u6db2\u8133\u95a2\u9580\u3068\u5e79\u7d30\u80de\u306e\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054-56\">\u8840\u6db2\u8133\u95a2\u9580\u3068\u5e79\u7d30\u80de\u306e\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-what-phase-1-and-phase-2-trials-show-for-dementia-stem-cell-therapy-52\">\u8a8d\u77e5\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u306b\u304a\u3051\u308b\u6700\u65b0\u306e\u81e8\u5e8a\u8a66\u9a13\u30c7\u30fc\u30bf<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u65e5\u672c\u306e\u81ea\u5bb6\u5e79\u7d30\u80de\u3068\u30de\u30ec\u30fc\u30b7\u30a2\u306e\u4ed6\u5bb6\u81cd\u5e2f\u7531\u6765msc\u306e\u9055\u3044-83\">\u65e5\u672c\u306e\u81ea\u5bb6\u5e79\u7d30\u80de\u3068\u30de\u30ec\u30fc\u30b7\u30a2\u306e\u4ed6\u5bb6\u81cd\u5e2f\u7531\u6765MSC\u306e\u9055\u3044<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u8a8d\u77e5\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u3092\u53d7\u3051\u305f\u5bb6\u65cf\u306e\u7d4c\u9a13-93\">\u8a8d\u77e5\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u3092\u53d7\u3051\u305f\u5bb6\u65cf\u306e\u7d4c\u9a13<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u8a8d\u77e5\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u306b\u5411\u3044\u3066\u3044\u308b\u65b9\u5411\u3044\u3066\u3044\u306a\u3044\u65b9-106\">\u8a8d\u77e5\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u306b\u5411\u3044\u3066\u3044\u308b\u65b9\u30fb\u5411\u3044\u3066\u3044\u306a\u3044\u65b9<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u8a8d\u77e5\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u306e\u30ea\u30b9\u30af\u3068\u6b63\u76f4\u306a\u9650\u754c-129\">\u8a8d\u77e5\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u306e\u30ea\u30b9\u30af\u3068\u6b63\u76f4\u306a\u9650\u754c<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-faq-about-dementia-stem-cell-therapy-111\">\u8a8d\u77e5\u75c7\u5e79\u7d30\u80de\u7642\u6cd5\u306b\u95a2\u3059\u308b\u3088\u304f\u3042\u308b\u8cea\u554f<\/a><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-considering-your-next-step-138\">\u3054\u5bb6\u65cf\u3067\u6b21\u306e\u4e00\u6b69\u3092\u8003\u3048\u308b\u305f\u3081\u306b<\/a><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-references-142\">\u53c2\u8003\u6587\u732e<\/a><\/li><\/ol><\/div>\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-why-dementia-progresses-despite-the-brains-natural-repair-capacity-10\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u8a8d\u77e5\u75c7\u306f\u306a\u305c\u81ea\u7136\u306b\u9032\u884c\u304c\u6b62\u307e\u3089\u306a\u3044\u306e\u304b<\/mark><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-the-limited-capacity-for-brain-self-repair-in-dementia-11\">\u8133\u306e\u81ea\u5df1\u4fee\u5fa9\u80fd\u529b\u306b\u306f\u9650\u754c\u304c\u3042\u308a\u307e\u3059<\/h3>\n\n\n\n<p 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class=\"wp-block-paragraph\">\u3057\u304b\u3057\u3001MSC\u306f\u300c\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u300d\u3068\u547c\u3070\u308c\u308b\u3001\u7d30\u80de\u3088\u308a\u3082\u306f\u308b\u304b\u306b\u5c0f\u3055\u306a\u30b7\u30b0\u30ca\u30eb\u7c92\u5b50\u3092\u653e\u51fa\u3057\u307e\u3059\u3002\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u306f\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u3001\u30de\u30a4\u30af\u30edRNA\u3001\u6210\u9577\u56e0\u5b50\u3092\u5185\u90e8\u306b\u8a70\u3081\u305f\u5c0f\u3055\u306a\u30ab\u30d7\u30bb\u30eb\u306e\u3088\u3046\u306a\u5b58\u5728\u3067\u3001\u8840\u6db2\u8133\u95a2\u9580\u3092\u901a\u308a\u629c\u3051\u3084\u3059\u3044\u3053\u3068\u304c\u308f\u304b\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u97d3\u56fd\u30fb\u5206\u5f53\uff23\uff28\uff21\u75c5\u9662\u306e\u30c1\u30fc\u30e0\u304c2021\u5e74\u306b\u5831\u544a\u3057\u305f\u7814\u7a76\u3067\u306f\u3001\u30cd\u30d7\u30ea\u30e9\u30a4\u30b7\u30f3\uff08\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u5206\u89e3\u9175\u7d20\uff09\u3092\u767a\u73fe\u3055\u305b\u305f\u81cd\u5e2f\u7531\u6765MSC\u306e\u9759\u8108\u6295\u4e0e\u3067\u3001\u7d30\u80de\u81ea\u4f53\u3067\u306f\u306a\u304f\u30a8\u30af\u30bd\u30bd\u30fc\u30e0\u304c\u8840\u6db2\u8133\u95a2\u9580\u3092\u8d8a\u3048\u3066\u8133\u306b\u5230\u9054\u3057\u3001\u52b9\u679c\u3092\u793a\u3057\u305f\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u300c\u7d30\u80de\u81ea\u4f53\u304c\u8133\u306b\u5165\u3089\u306a\u3044\u3068\u52b9\u304b\u306a\u3044\u300d\u3068\u3044\u3046\u5f93\u6765\u306e\u60f3\u5b9a\u304b\u3089\u3001\u300c\u30b7\u30b0\u30ca\u30eb\u3060\u3051\u3067\u3082\u8133\u5185\u3067\u4f5c\u7528\u3059\u308b\u300d\u3068\u3044\u3046\u7406\u89e3\u3078\u3068\u3001\u7814\u7a76\u306e\u67a0\u7d44\u307f\u306f\u78ba\u5b9f\u306b\u9032\u3093\u3067\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-what-phase-1-and-phase-2-trials-show-for-dementia-stem-cell-therapy-52\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u8a8d\u77e5\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u306b\u304a\u3051\u308b\u6700\u65b0\u306e\u81e8\u5e8a\u8a66\u9a13\u30c7\u30fc\u30bf<\/mark><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"800\" height=\"558\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-Image-9.webp\" alt=\"\u8a8d\u77e5\u75c7\u60a3\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305f\u9593\u8449\u7cfb\u5e79\u7d30\u80de\u6cbb\u7642\u306e\u81e8\u5e8a\u8a66\u9a13\u306b\u304a\u3051\u308b\u8a8d\u77e5\u6a5f\u80fd\u30b9\u30b3\u30a2\u306e\u63a8\u79fb\u3092\u793a\u3059\u30b0\u30e9\u30d5\n\" class=\"wp-image-24915\" style=\"width:592px\" srcset=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-Image-9.webp 800w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-Image-9-300x209.webp 300w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/05\/Article-Image-9-768x536.webp 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption class=\"wp-element-caption\">Lomecel-B\uff08laromestrocel\uff09\u306e\u7b2c2a\u76f8\u8a66\u9a13\uff08Nature Medicine, 2024\uff09\u3067\u306f\u3001\u6cbb\u7642\u7fa4\u3067\u5168\u8133\u840e\u7e2e\u304c48.4%\u3001\u5de6\u6d77\u99ac\u840e\u7e2e\u304c61.9%\u305d\u308c\u305e\u308c\u30d7\u30e9\u30bb\u30dc\u7fa4\u3088\u308a\u9045\u5ef6\u3057\u307e\u3057\u305f\u3002<\/figcaption><\/figure>\n<\/div>\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-key-clinical-trials-in-dementia-stem-cell-research-53\">\u4e3b\u8981\u306a\u81e8\u5e8a\u8a66\u9a13\u306e\u7d50\u679c<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u5e79\u7d30\u80de\u6cbb\u7642\u306e\u8a8d\u77e5\u75c7\u306b\u5bfe\u3059\u308b\u81e8\u5e8a\u30a8\u30d3\u30c7\u30f3\u30b9\u306f\u3001\u6574\u5f62\u5916\u79d1\u3084\u5fc3\u81d3\u9818\u57df\u306b\u6bd4\u3079\u308b\u3068\u65b0\u3057\u3044\u5206\u91ce\u3067\u3059\u304c\u3001\u6c7a\u3057\u3066\u7a7a\u767d\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u97d3\u56fd\u30fb\u30b5\u30e0\u30b9\u30f3\u533b\u7642\u30bb\u30f3\u30bf\u30fc\u306e Kim \u6559\u6388\u3089\u306e\u30c1\u30fc\u30e0\u306f\u3001\u8efd\u5ea6\u301c\u4e2d\u7b49\u5ea6\u306e\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u578b\u8a8d\u77e5\u75c7\u60a3\u80059\u540d\u306b\u5bfe\u3057\u3001\u81cd\u5e2f\u8840\u7531\u6765\u306e\u9593\u8449\u7cfb\u5e79\u7d30\u80de\u3092\u8133\u5185\u306b\u76f4\u63a5\u6ce8\u5c04\u3059\u308b\u7b2c1\u76f8\u8a66\u9a13\u3092\u5b9f\u65bd\u3057\u307e\u3057\u305f\u30022015\u5e74\u306b &#8220;Alzheimer&#8217;s &amp; Dementia: Translational Research&#8221; \u8a8c\u3067\u767a\u8868\u3055\u308c\u305f\u7d50\u679c\u3067\u306f\u3001\u5b89\u5168\u6027\u304c\u78ba\u8a8d\u3055\u308c\u3001\u91cd\u7be4\u306a\u526f\u4f5c\u7528\u306f\u8a8d\u3081\u3089\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u540c\u30c1\u30fc\u30e0\u306f2021\u5e74\u306b\u3082\u3001\u8133\u5ba4\u5185\u6295\u4e0e\u306b\u3088\u308b\u5225\u306e\u7b2c1\u76f8\u8a66\u9a13\u3092 Alzheimer&#8217;s Research &amp; Therapy \u8a8c\u306b\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7279\u306b\u6ce8\u76ee\u3055\u308c\u3066\u3044\u308b\u306e\u304c\u3001\u7c73\u56fd Longeveron \u793e\u304c\u958b\u767a\u3059\u308b Lomecel-B\uff08laromestrocel\uff09\u3067\u3059\u3002\u3053\u308c\u306f\u3001\u5065\u5eb7\u306a\u30c9\u30ca\u30fc\u306e\u9aa8\u9ac4\u304b\u3089\u63a1\u53d6\u3057\u305f\u540c\u7a2e\uff08\u4ed6\u5bb6\uff09\u9593\u8449\u7cfb\u5e79\u7d30\u80de\u3092\u88fd\u5264\u5316\u3057\u305f\u3082\u306e\u3067\u3001\u8efd\u5ea6\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u578b\u8a8d\u77e5\u75c7\u3092\u5bfe\u8c61\u3068\u3057\u305f\u7b2c2a\u76f8 CLEAR MIND \u8a66\u9a13\u306e\u7d50\u679c\u304c2024\u5e74\u306b Nature Medicine \u8a8c\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u8a66\u9a13\u306f\u3001\u7c73\u56fd10\u65bd\u8a2d\u3067\u5b9f\u65bd\u3055\u308c\u305f\u30e9\u30f3\u30c0\u30e0\u5316\u4e8c\u91cd\u76f2\u691c\u30d7\u30e9\u30bb\u30dc\u5bfe\u7167\u8a66\u9a13\u3067\u300149\u540d\u306e\u53c2\u52a0\u8005\u304c4\u7fa4\uff08\u30d7\u30e9\u30bb\u30dc\u3001\u5358\u56de\u6295\u4e0e\u3001\u8907\u6570\u56de\u6295\u4e0e\u306a\u3069\uff09\u306b\u5272\u308a\u4ed8\u3051\u3089\u308c\u307e\u3057\u305f\u3002\u7d50\u679c\u3068\u3057\u3066\u3001Lomecel-B \u306f\u30d7\u30e9\u30bb\u30dc\u3068\u6bd4\u8f03\u3057\u3066\u5168\u8133\u306e\u4f53\u7a4d\u6e1b\u5c11\u309248.4%\u9045\u3089\u305b\u3001\u5de6\u6d77\u99ac\u306e\u4f53\u7a4d\u6e1b\u5c11\u309261.9%\u9045\u3089\u305b\u3001\u795e\u7d4c\u708e\u75c7\u30de\u30fc\u30ab\u30fc\u306e\u4f4e\u4e0b\u3082\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002\u91cd\u5927\u306a\u6cbb\u7642\u95a2\u9023\u6709\u5bb3\u4e8b\u8c61\u3001\u8f38\u6ce8\u95a2\u9023\u53cd\u5fdc\u3001ARIA\uff08\u30a2\u30df\u30ed\u30a4\u30c9\u95a2\u9023\u753b\u50cf\u7570\u5e38\uff09\u306f\u3044\u305a\u308c\u3082\u5831\u544a\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8840\u7ba1\u6027\u8a8d\u77e5\u75c7\u306b\u3064\u3044\u3066\u3082\u3001\u97d3\u56fd\u30fb\u9ad8\u9e97\u5927\u5b66\u6821\u5b89\u5ca9\u75c5\u9662\u306e\u30c1\u30fc\u30e0\u304c2025\u5e74\u306b\u52d5\u7269\u30e2\u30c7\u30eb\u3067\u795e\u7d4c\u524d\u99c6\u7d30\u80de\u306b\u3088\u308b\u8a8d\u77e5\u6a5f\u80fd\u6539\u5584\u3092\u5831\u544a\u3059\u308b\u306a\u3069\u3001\u7814\u7a76\u306f\u9032\u3093\u3067\u3044\u307e\u3059\u3002\u30d2\u30c8\u3092\u5bfe\u8c61\u3068\u3057\u305f\u5927\u898f\u6a21\u8a66\u9a13\u306f\u307e\u3060\u3053\u308c\u304b\u3089\u306e\u6bb5\u968e\u3067\u3059\u304c\u3001\u30e1\u30ab\u30cb\u30ba\u30e0\u4e0a\u306e\u6839\u62e0\u306f\u7a4d\u307f\u91cd\u306a\u3063\u3066\u304d\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-\u6570\u5b57\u3092\u3069\u3046\u8aad\u3080\u304b-78\">\u6570\u5b57\u3092\u3069\u3046\u8aad\u3080\u304b<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u3089\u306e\u8a66\u9a13\u7d50\u679c\u3092\u3001\u3054\u5bb6\u65cf\u306e\u610f\u601d\u6c7a\u5b9a\u306b\u5f79\u7acb\u3064\u8a00\u8449\u3067\u7ffb\u8a33\u3057\u3066\u304a\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u300c\u8133\u840e\u7e2e\u309248.4%\u9045\u3089\u305b\u305f\u300d\u3068\u3044\u3046\u6570\u5b57\u306f\u5287\u7684\u306b\u805e\u3053\u3048\u308b\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u304c\u3001\u305d\u308c\u306f\u300c\u9032\u884c\u3092\u9045\u3089\u305b\u305f\u300d\u306e\u3067\u3042\u3063\u3066\u3001\u300c\u5931\u308f\u308c\u305f\u6a5f\u80fd\u3092\u53d6\u308a\u623b\u3057\u305f\u300d\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u30023\u5e74\u524d\u306b\u623b\u308c\u308b\u308f\u3051\u3067\u306f\u306a\u3044\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p 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id=\"aioseo-\u5e79\u7d30\u80de\u6cbb\u7642\u304c\u3067\u304d\u306a\u3044\u3053\u3068-135\">\u5e79\u7d30\u80de\u6cbb\u7642\u304c\u3067\u304d\u306a\u3044\u3053\u3068<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u3053\u306f\u3001\u4f55\u5ea6\u3067\u3082\u7e70\u308a\u8fd4\u3057\u305f\u3044\u90e8\u5206\u3067\u3059\u3002<\/p>\n\n\n\n<p 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style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u8a8d\u77e5\u75c7\u5e79\u7d30\u80de\u7642\u6cd5\u306b\u95a2\u3059\u308b\u3088\u304f\u3042\u308b\u8cea\u554f<\/mark><\/h2>\n\n\n\n<div data-wp-context=\"{ &quot;autoclose&quot;: false, &quot;accordionItems&quot;: [] }\" data-wp-interactive=\"core\/accordion\" role=\"group\" class=\"wp-block-accordion is-layout-flow wp-block-accordion-is-layout-flow\">\n<div data-wp-class--is-open=\"state.isOpen\" data-wp-context=\"{ &quot;id&quot;: &quot;accordion-item-1&quot;, &quot;openByDefault&quot;: false }\" data-wp-init=\"callbacks.initAccordionItems\" data-wp-on-window--hashchange=\"callbacks.hashChange\" class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h4 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-1-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" id=\"accordion-item-1\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span class=\"wp-block-accordion-heading__toggle-title\">\u8a8d\u77e5\u75c7\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u306e\u52b9\u679c\u306f\u3069\u306e\u304f\u3089\u3044\u6301\u7d9a\u3057\u307e\u3059\u304b\uff1f<\/span><span class=\"wp-block-accordion-heading__toggle-icon\" aria-hidden=\"true\">+<\/span><\/button><\/h4>\n\n\n\n<div aria-labelledby=\"accordion-item-1\" data-wp-bind--hidden=\"state.isHidden\" data-wp-on--beforematch=\"actions.handleBeforeMatch\" id=\"accordion-item-1-panel\" role=\"region\" class=\"wp-block-accordion-panel is-layout-flow wp-block-accordion-panel-is-layout-flow\">\n<p class=\"wp-block-paragraph\">\u3053\u308c\u307e\u3067\u306b\u767a\u8868\u3055\u308c\u3066\u3044\u308b\u81e8\u5e8a\u8a66\u9a13\u306e\u30c7\u30fc\u30bf\u306b\u3088\u308c\u3070\u3001\u52b9\u679c\u304c\u73fe\u308c\u308b\u5834\u5408\u3001\u591a\u304f\u306f\u6cbb\u7642\u5f8c8\u301c16\u9031\u304b\u3089\u5909\u5316\u304c\u898b\u3048\u306f\u3058\u3081\u3001\u305d\u306e\u5f8c6\u301c12\u304b\u6708\u304b\u3051\u3066\u751f\u7269\u5b66\u7684\u306a\u4f5c\u7528\u304c\u6210\u719f\u3057\u3066\u3044\u304f\u7d4c\u904e\u3092\u305f\u3069\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u516c\u8868\u3055\u308c\u3066\u3044\u308b\u8ffd\u8de1\u671f\u9593\u306e\u6700\u9577\u306f2\u301c3\u5e74\u7a0b\u5ea6\u3067\u3001Lomecel-B 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data-wp-context=\"{ &quot;autoclose&quot;: false, &quot;accordionItems&quot;: [] }\" data-wp-interactive=\"core\/accordion\" role=\"group\" class=\"wp-block-accordion is-layout-flow wp-block-accordion-is-layout-flow\">\n<div data-wp-class--is-open=\"state.isOpen\" data-wp-context=\"{ &quot;id&quot;: &quot;accordion-item-2&quot;, &quot;openByDefault&quot;: false }\" data-wp-init=\"callbacks.initAccordionItems\" data-wp-on-window--hashchange=\"callbacks.hashChange\" class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h4 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-2-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" id=\"accordion-item-2\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span 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class=\"wp-block-paragraph\">\u4e21\u8005\u306e\u4f5c\u7528\u7d4c\u8def\u306f\u307e\u3063\u305f\u304f\u7570\u306a\u308a\u307e\u3059\u3002\u5f93\u6765\u85ac\u306f\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u306e\u8abf\u6574\u3084\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u306e\u9664\u53bb\u3092\u76ee\u6307\u3059\u306e\u306b\u5bfe\u3057\u3001\u9593\u8449\u7cfb\u5e79\u7d30\u80de\u306f\u708e\u75c7\u306e\u8abf\u6574\u3001\u751f\u304d\u6b8b\u3063\u3066\u3044\u308b\u795e\u7d4c\u7d30\u80de\u306e\u30b5\u30dd\u30fc\u30c8\u3001\u8133\u8840\u6d41\u306e\u6539\u5584\u3068\u3044\u3046\u5f62\u3067\u4f5c\u7528\u3057\u307e\u3059\u3002\u3053\u308c\u307e\u3067\u306e\u81e8\u5e8a\u8a66\u9a13\u3067\u3001MSC\u6cbb\u7642\u3068\u6a19\u6e96\u7684\u306a\u8a8d\u77e5\u75c7\u6cbb\u7642\u85ac\u3068\u306e\u9593\u306b\u6709\u5bb3\u306a\u76f8\u4e92\u4f5c\u7528\u306f\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u304a\u85ac\u306e\u8abf\u6574\u306b\u95a2\u3059\u308b\u5224\u65ad\u306f\u3001\u5fc5\u305a\u4e3b\u6cbb\u533b\u306e\u5148\u751f\u306e\u3082\u3068\u3067\u3001\u6642\u9593\u3092\u304b\u3051\u3066\u89b3\u5bdf\u3055\u308c\u308b\u81e8\u5e8a\u7684\u306a\u5909\u5316\u306b\u57fa\u3065\u3044\u3066\u884c\u308f\u308c\u308b\u3079\u304d\u3082\u306e\u3067\u3059\u3002\u5e79\u7d30\u80de\u6cbb\u7642\u306e\u524d\u5f8c\u3067\u60a3\u8005\u3055\u3093\u5074\u306e\u5224\u65ad\u306b\u3088\u3063\u3066\u5909\u66f4\u3055\u308c\u308b\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div data-wp-context=\"{ &quot;autoclose&quot;: false, &quot;accordionItems&quot;: [] }\" data-wp-interactive=\"core\/accordion\" role=\"group\" class=\"wp-block-accordion is-layout-flow wp-block-accordion-is-layout-flow\">\n<div data-wp-class--is-open=\"state.isOpen\" data-wp-context=\"{ &quot;id&quot;: &quot;accordion-item-3&quot;, &quot;openByDefault&quot;: false }\" data-wp-init=\"callbacks.initAccordionItems\" data-wp-on-window--hashchange=\"callbacks.hashChange\" class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h4 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-3-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" id=\"accordion-item-3\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span class=\"wp-block-accordion-heading__toggle-title\">\u65e5\u672c\u56fd\u5185\u306e\u81ea\u5bb6\u6cbb\u7642\u3068\u3001\u30de\u30ec\u30fc\u30b7\u30a2\u306e\u4ed6\u5bb6\u81cd\u5e2f\u7531\u6765\u6cbb\u7642\u306f\u3069\u3046\u9055\u3044\u307e\u3059\u304b\uff1f<\/span><span class=\"wp-block-accordion-heading__toggle-icon\" aria-hidden=\"true\">+<\/span><\/button><\/h4>\n\n\n\n<div aria-labelledby=\"accordion-item-3\" data-wp-bind--hidden=\"state.isHidden\" data-wp-on--beforematch=\"actions.handleBeforeMatch\" id=\"accordion-item-3-panel\" role=\"region\" class=\"wp-block-accordion-panel is-layout-flow wp-block-accordion-panel-is-layout-flow\">\n<p class=\"wp-block-paragraph\">\u6700\u3082\u5927\u304d\u306a\u9055\u3044\u306f\u300c\u7d30\u80de\u306e\u51fa\u3069\u3053\u308d\u300d\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u65e5\u672c\u3067\u306f\u73fe\u5728\u306e\u518d\u751f\u533b\u7642\u5236\u5ea6\u306e\u4e0b\u3067\u3001\u81ea\u5bb6\u7531\u6765\u306e\u6cbb\u7642\u304c\u4e2d\u5fc3\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u60a3\u8005\u3055\u3093\u3054\u81ea\u8eab\u306e\u8102\u80aa\u7d44\u7e54\u3084\u9aa8\u9ac4\u304b\u3089\u7d30\u80de\u3092\u63a1\u53d6\u3057\u3001\u57f9\u990a\u3057\u305f\u3046\u3048\u3067\u70b9\u6ef4\u3067\u623b\u3059\u65b9\u5f0f\u3067\u3001\u514d\u75ab\u62d2\u7d76\u306e\u30ea\u30b9\u30af\u304c\u306a\u3044\u3053\u3068\u304c\u6700\u5927\u306e\u30e1\u30ea\u30c3\u30c8\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e00\u65b9\u3067\u3001\u3054\u9ad8\u9f62\u306e\u60a3\u8005\u3055\u3093\u3067\u306f\u7121\u8996\u3067\u304d\u306a\u3044\u30c7\u30e1\u30ea\u30c3\u30c8\u3082\u3042\u308a\u307e\u3059\u3002\u305d\u308c\u306f\u300c\u7d30\u80de\u306e\u8cea\u304c\u3001\u3054\u672c\u4eba\u306e\u5e74\u9f62\u3068\u5065\u5eb7\u72b6\u614b\u3092\u53cd\u6620\u3057\u3066\u3057\u307e\u3046\u300d\u3068\u3044\u3046\u70b9\u3067\u3059\u300270\u4ee3\u3067\u795e\u7d4c\u5909\u6027\u75be\u60a3\u304c\u9032\u884c\u3057\u3066\u3044\u308b\u3054\u672c\u4eba\u306e\u7d30\u80de\u306f\u3001\u9577\u5e74\u306e\u7d30\u80de\u30b9\u30c8\u30ec\u30b9\u306b\u3088\u308a\u3001\u5897\u6b96\u80fd\u529b\u3084\u5206\u6ccc\u6a5f\u80fd\u304c\u82e5\u3044\u7d30\u80de\u3088\u308a\u660e\u3089\u304b\u306b\u4f4e\u4e0b\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30de\u30ec\u30fc\u30b7\u30a2\u3067\u79c1\u305f\u3061\u304c\u63d0\u4f9b\u3057\u3066\u3044\u308b\u306e\u306f\u3001\u5065\u5eb7\u306a\u30c9\u30ca\u30fc(\u51fa\u7523\u6642\u306b\u540c\u610f\u3092\u5f97\u305f\u65b9\u306e\u81cd\u5e2f)\u304b\u3089\u63a1\u53d6\u3055\u308c\u305f\u4ed6\u5bb6MSC\u3067\u3001\u7279\u306b\u30ef\u30eb\u30c8\u30f3\u30b8\u30a7\u30ea\u30fc\u3068\u547c\u3070\u308c\u308b\u90e8\u4f4d\u304b\u3089\u5f97\u3089\u308c\u308b\u3001\u6700\u3082\u82e5\u3044\u4e16\u4ee3\u306eMSC\u3067\u3059\u3002\u3053\u308c\u3089\u306f\u514d\u75ab\u8abf\u6574\u80fd\u529b\u304c\u9ad8\u304f\u3001\u898f\u683c\u5316\u3055\u308c\u305f\u30d0\u30c3\u30c1\u3067\u54c1\u8cea\u7ba1\u7406\u3055\u308c\u3066\u3044\u308b\u305f\u3081\u3001\u751f\u5b58\u7387\u3084\u52b9\u529b\u3092\u6295\u4e0e\u524d\u306b\u691c\u8a3c\u3067\u304d\u307e\u3059\u3002\u60a3\u8005\u3055\u3093\u5074\u306b\u7d30\u80de\u63a1\u53d6\u306e\u305f\u3081\u306e\u51e6\u7f6e\u3082\u4e0d\u8981\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8a8d\u77e5\u75c7\u9818\u57df\u306b\u304a\u3051\u308b\u81ea\u5bb6 vs \u4ed6\u5bb6\u306e\u982d\u304b\u3089\u982d\u3078\u306e\u5927\u898f\u6a21\u6bd4\u8f03\u306f\u307e\u3060\u5b8c\u4e86\u3057\u3066\u3044\u307e\u305b\u3093\u304c\u3001\u3054\u9ad8\u9f62\u306e\u60a3\u8005\u3055\u3093\u306b\u3068\u3063\u3066\u3001\u81cd\u5e2f\u7531\u6765\u7d30\u80de\u306e\u300c\u82e5\u3055\u300d\u306f\u610f\u5473\u306e\u3042\u308b\u8003\u616e\u8981\u7d20\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div data-wp-context=\"{ &quot;autoclose&quot;: false, &quot;accordionItems&quot;: [] }\" data-wp-interactive=\"core\/accordion\" role=\"group\" class=\"wp-block-accordion is-layout-flow wp-block-accordion-is-layout-flow\">\n<div data-wp-class--is-open=\"state.isOpen\" data-wp-context=\"{ &quot;id&quot;: &quot;accordion-item-4&quot;, &quot;openByDefault&quot;: false }\" data-wp-init=\"callbacks.initAccordionItems\" data-wp-on-window--hashchange=\"callbacks.hashChange\" class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h4 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-4-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" id=\"accordion-item-4\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span class=\"wp-block-accordion-heading__toggle-title\">\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u578b\u30fb\u8840\u7ba1\u6027\u30fb\u30ec\u30d3\u30fc\u5c0f\u4f53\u578b\u306e\u3046\u3061\u3001\u6700\u3082\u7814\u7a76\u304c\u9032\u3093\u3067\u3044\u308b\u306e\u306f\u3069\u308c\u3067\u3059\u304b\uff1f<\/span><span class=\"wp-block-accordion-heading__toggle-icon\" aria-hidden=\"true\">+<\/span><\/button><\/h4>\n\n\n\n<div aria-labelledby=\"accordion-item-4\" data-wp-bind--hidden=\"state.isHidden\" data-wp-on--beforematch=\"actions.handleBeforeMatch\" id=\"accordion-item-4-panel\" role=\"region\" class=\"wp-block-accordion-panel is-layout-flow wp-block-accordion-panel-is-layout-flow\">\n<p class=\"wp-block-paragraph\">\u81e8\u5e8a\u8a66\u9a13\u306e\u84c4\u7a4d\u3068\u3044\u3046\u70b9\u3067\u306f\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u578b\u8a8d\u77e5\u75c7\u304c\u5727\u5012\u7684\u306b\u591a\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u97d3\u56fd\u30fb\u30b5\u30e0\u30b9\u30f3\u533b\u7642\u30bb\u30f3\u30bf\u30fc\u306e Kim \u6559\u6388\u3089\u306e\u8a66\u9a13\u3001\u7c73\u56fd Longeveron \u793e\u306e Lomecel-B \u7b2c1\u76f8\u8a66\u9a13\u304a\u3088\u3073 CLEAR MIND \u7b2c2a\u76f8\u8a66\u9a13\u306a\u3069\u3001\u767b\u9332\u3055\u308c\u3066\u3044\u308b\u4e3b\u8981\u306a\u81e8\u5e8a\u8a66\u9a13\u306e\u307b\u3068\u3093\u3069\u304c\u3001\u8efd\u5ea6\u304b\u3089\u4e2d\u7b49\u5ea6\u306e\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u578b\u3092\u5bfe\u8c61\u3068\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8840\u7ba1\u6027\u8a8d\u77e5\u75c7\u306b\u3064\u3044\u3066\u3082\u3001\u52d5\u7269\u5b9f\u9a13\u3068\u5c0f\u898f\u6a21\u306a\u30d2\u30c8\u8a66\u9a13\u3092\u4e2d\u5fc3\u306b\u7814\u7a76\u304c\u9032\u307f\u3064\u3064\u3042\u308a\u3001\u9ad8\u9e97\u5927\u5b66\u6821\u3092\u306f\u3058\u3081\u8907\u6570\u306e\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u304c\u6d3b\u767a\u306b\u53d6\u308a\u7d44\u3093\u3067\u3044\u307e\u3059\u3002\u6df7\u5408\u578b(\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc+\u8840\u7ba1\u6027)\u3067\u306f\u3001\u708e\u75c7\u8abf\u6574\u4f5c\u7528\u3068\u8840\u7ba1\u65b0\u751f\u4f5c\u7528\u306e\u4e21\u65b9\u304c\u671f\u5f85\u3055\u308c\u307e\u3059\u304c\u3001\u8a66\u9a13\u306e\u7d44\u307f\u5165\u308c\u57fa\u6e96\u3068\u3057\u3066\u660e\u793a\u7684\u306b\u5bfe\u8c61\u3068\u3055\u308c\u308b\u4f8b\u306f\u591a\u304f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p 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class=\"wp-block-paragraph\">\u3054\u6c7a\u65ad\u306e\u524d\u3067\u69cb\u3044\u307e\u305b\u3093\u3002\u8a3a\u65ad\u66f8\u3001\u753b\u50cf\u3001\u73fe\u5728\u306e\u51e6\u65b9\u3092\u304a\u6301\u3061\u3044\u305f\u3060\u3051\u308c\u3070\u3001\u305d\u308c\u3092\u4e00\u7dd2\u306b\u62dd\u898b\u3057\u306a\u304c\u3089\u8003\u3048\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-references-142\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u53c2\u8003\u6587\u732e<\/mark><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>GBD 2019 Dementia Forecasting Collaborators. &#8220;Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019.&#8221; <em>Lancet Public Health.<\/em> 2022;7(2):e105\u2013e125. <a href=\"https:\/\/doi.org\/10.1016\/S2468-2667(21)00249-8\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1016\/S2468-2667(21)00249-8<\/a><\/li>\n\n\n\n<li>Kim HJ, Seo SW, Chang JW, et al. &#8220;Stereotactic brain injection of human umbilical cord blood mesenchymal stem cells in patients with Alzheimer&#8217;s disease dementia: A phase 1 clinical trial.&#8221; <em>Alzheimer&#8217;s &amp; Dementia: Translational Research &amp; Clinical Interventions.<\/em> 2015;1(2):95\u2013102. <a href=\"https:\/\/doi.org\/10.1016\/j.trci.2015.06.007\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1016\/j.trci.2015.06.007<\/a><\/li>\n\n\n\n<li>Brody M, Agronin M, Herskowitz BJ, et al. &#8220;Results and insights from a phase I clinical trial of Lomecel-B for Alzheimer&#8217;s disease.&#8221; <em>Alzheimer&#8217;s &amp; Dementia.<\/em> 2023;19(1):261\u2013273. <a href=\"https:\/\/doi.org\/10.1002\/alz.12651\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1002\/alz.12651<\/a><\/li>\n\n\n\n<li>Kim HJ, Cho KR, Jang H, et al. &#8220;Intracerebroventricular injection of human umbilical cord blood mesenchymal stem cells in patients with Alzheimer&#8217;s disease dementia: a phase I clinical trial.&#8221; <em>Alzheimer&#8217;s Research &amp; Therapy.<\/em> 2021;13(1):154. <a href=\"https:\/\/doi.org\/10.1186\/s13195-021-00897-2\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1186\/s13195-021-00897-2<\/a><\/li>\n\n\n\n<li>Liu XY, Yang LP, Zhao L. &#8220;Stem cell therapy for Alzheimer&#8217;s disease.&#8221; <em>World Journal of Stem Cells.<\/em> 2020;12(8):787\u2013802. <a href=\"https:\/\/doi.org\/10.4252\/wjsc.v12.i8.787\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.4252\/wjsc.v12.i8.787<\/a><\/li>\n\n\n\n<li>Bonsack B, Heyck M, Kingsbury C, et al. &#8220;Mesenchymal stem cell therapy alleviates the neuroinflammation associated with acquired brain injury.&#8221; <em>CNS Neuroscience &amp; Therapeutics.<\/em> 2020;26(6):603\u2013615. <a href=\"https:\/\/doi.org\/10.1111\/cns.13378\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1111\/cns.13378<\/a><\/li>\n\n\n\n<li>Selkoe DJ, Hardy J. &#8220;The amyloid hypothesis of Alzheimer&#8217;s disease at 25 years.&#8221; <em>EMBO Molecular Medicine.<\/em> 2016;8(6):595\u2013608. <a href=\"https:\/\/doi.org\/10.15252\/emmm.201606210\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.15252\/emmm.201606210<\/a><\/li>\n\n\n\n<li>Hampel H, Hardy J, Blennow K, et al. &#8220;The amyloid-\u03b2 pathway in Alzheimer&#8217;s disease.&#8221; <em>Molecular Psychiatry.<\/em> 2021;26(10):5481\u20135503. <a href=\"https:\/\/doi.org\/10.1038\/s41380-021-01249-0\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1038\/s41380-021-01249-0<\/a><\/li>\n<\/ol>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\t\t<div data-elementor-type=\"section\" data-elementor-id=\"21873\" class=\"elementor 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