{"id":24743,"date":"2026-04-30T13:34:57","date_gmt":"2026-04-30T05:34:57","guid":{"rendered":"https:\/\/stemcell-malaysia.com\/?page_id=24743"},"modified":"2026-07-31T12:26:20","modified_gmt":"2026-07-31T04:26:20","slug":"fatty-liver-disease","status":"publish","type":"page","link":"https:\/\/stemcell-malaysia.com\/ja\/conditions\/fatty-liver-disease\/","title":{"rendered":"\u8102\u80aa\u809d\u306e\u5e79\u7d30\u80de\u6cbb\u7642\uff5c\u751f\u6d3b\u7fd2\u6163\u306e\u6539\u5584\u3060\u3051\u3067\u306f\u4e0b\u304c\u3089\u306a\u3044\u809d\u81d3\u6570\u5024\u306f\u672c\u5f53\u306b\u6539\u5584\u3067\u304d\u308b\u306e\u304b"},"content":{"rendered":"\n<h1 class=\"wp-block-heading has-text-align-center\">\u8102\u80aa\u809d\u306e\u5e79\u7d30\u80de\u6cbb\u7642\uff5c\u751f\u6d3b\u7fd2\u6163\u306e\u6539\u5584\u3060\u3051\u3067\u306f\u4e0b\u304c\u3089\u306a\u3044\u809d\u81d3\u6570\u5024\u306f\u672c\u5f53\u306b\u6539\u5584\u3067\u304d\u308b\u306e\u304b<\/h1>\n\n\n<div 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class=\"wp-block-heading\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u76ee\u6b21<\/mark><\/h2>\n\n\n<div class=\"wp-block-aioseo-table-of-contents\"><ol><li><a class=\"aioseo-toc-item\" href=\"#aioseo-why-fatty-liver-disease-quietly-worsens-without-visible-symptoms-9\">\u306a\u305c\u8102\u80aa\u809d\u306f\u6c17\u3065\u304b\u306a\u3044\u3046\u3061\u306b\u9032\u884c\u3059\u308b\u306e\u304b<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u8102\u80aa\u809d\u306b\u5bfe\u3059\u308b\u5f93\u6765\u6cbb\u7642\u306e\u9650\u754c-20\">\u8102\u80aa\u809d\u306b\u5bfe\u3059\u308b\u5f93\u6765\u6cbb\u7642\u306e\u9650\u754c<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-how-stem-cell-therapy-targets-fatty-liver-disease-three-biological-mechanisms-33\">\u8102\u80aa\u809d\u306b\u5bfe\u3059\u308b\u5e79\u7d30\u80de\u6cbb\u7642\u3067\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u81e8\u5e8a\u30c7\u30fc\u30bf<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-what-the-clinical-data-shows-about-stem-cell-therapy-for-fatty-liver-disease-48\">\u8102\u80aa\u809d\u306b\u5bfe\u3059\u308b\u5e79\u7d30\u80de\u7642\u6cd5\u306b\u95a2\u3059\u308b\u81e8\u5e8a\u30c7\u30fc\u30bf\u304c\u793a\u3059\u3082\u306e<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u65e5\u672c\u306e\u81ea\u5bb6\u5e79\u7d30\u80de\u6cbb\u7642\u3068\u30de\u30ec\u30fc\u30b7\u30a2\u306e\u4ed6\u5bb6\u81cd\u5e2f\u7531\u6765msc\u6cbb\u7642\u306e\u9055\u3044-68\">\u65e5\u672c\u306e\u81ea\u5bb6\u5e79\u7d30\u80de\u6cbb\u7642\u3068\u30de\u30ec\u30fc\u30b7\u30a2\u306e\u4ed6\u5bb6\u81cd\u5e2f\u7531\u6765MSC\u6cbb\u7642\u306e\u9055\u3044<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u8102\u80aa\u809d\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u3092\u53d7\u3051\u305f\u60a3\u8005\u69d8\u306e\u4f53\u9a13-78\">\u8102\u80aa\u809d\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u3092\u53d7\u3051\u305f\u60a3\u8005\u69d8\u306e\u4f53\u9a13<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u8102\u80aa\u809d\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u306b\u5411\u3044\u3066\u3044\u308b\u65b9\u5411\u3044\u3066\u3044\u306a\u3044\u65b9-87\">\u8102\u80aa\u809d\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u306b\u5411\u3044\u3066\u3044\u308b\u65b9\u30fb\u5411\u3044\u3066\u3044\u306a\u3044\u65b9<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u30de\u30ec\u30fc\u30b7\u30a2\u3067\u8102\u80aa\u809d\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u3092\u53d7\u3051\u308b\u6d41\u308c-99\">\u30de\u30ec\u30fc\u30b7\u30a2\u3067\u8102\u80aa\u809d\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u3092\u53d7\u3051\u308b\u6d41\u308c<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-\u8102\u80aa\u809d\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u306b\u4f34\u3046\u30ea\u30b9\u30af\u3068\u6b63\u76f4\u306a\u9650\u754c-110\">\u8102\u80aa\u809d\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u306b\u4f34\u3046\u30ea\u30b9\u30af\u3068\u6b63\u76f4\u306a\u9650\u754c<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-faq-about-fatty-liver-disease-stem-cell-therapy-116\">\u8102\u80aa\u809d\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u3067\u3088\u304f\u3042\u308b\u8cea\u554f<\/a><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-next-step-154\">\u6b21\u306e\u4e00\u6b69<\/a><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-references-158\">\u53c2\u8003\u6587\u732e<\/a><\/li><\/ol><\/div>\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-why-fatty-liver-disease-quietly-worsens-without-visible-symptoms-9\"><mark style=\"background-color:#dce9f5\" 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class=\"wp-block-paragraph\">\u305d\u306e\u7d50\u679c\u3001\u591a\u304f\u306e\u65b9\u304c\u300c\u3042\u308b\u7a0b\u5ea6\u307e\u3067\u306f\u4e0b\u304c\u3063\u305f\u304c\u3001\u305d\u3053\u304b\u3089\u52d5\u304b\u306a\u3044\u300d\u3068\u3044\u3046\u30d7\u30e9\u30c8\u30fc\uff08\u505c\u6ede\u671f\uff09\u306b\u5230\u9054\u3057\u307e\u3059\u30021\u301c2\u5e74\u5358\u4f4d\u3067\u751f\u6d3b\u3092\u5909\u3048\u3066\u3082\u3001ALT\u304c\u6b63\u5e38\u7bc4\u56f2\u306b\u307e\u3067\u4e0b\u304c\u308a\u304d\u3089\u306a\u3044\u3002FibroScan\u306e\u786c\u5ea6\u304c\u5909\u308f\u3089\u306a\u3044\u3002\u3051\u308c\u3069\u3082\u3001\u9032\u884c\u3082\u5b8c\u5168\u306b\u306f\u6b62\u307e\u3063\u3066\u3044\u306a\u3044\u3002\u3053\u306e\u5c64\u306b\u5bfe\u3057\u3066\u3001\u73fe\u5728\u306e\u4fdd\u967a\u8a3a\u7642\u306f\u300c\u3082\u3046\u5c11\u3057\u9811\u5f35\u3063\u3066\u304f\u3060\u3055\u3044\u300d\u4ee5\u4e0a\u306e\u9078\u629e\u80a2\u3092\u6301\u3061\u5408\u308f\u305b\u3066\u3044\u306a\u3044\u306e\u304c\u5b9f\u60c5\u3067\u3059\u3002<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-\u8102\u80aa\u809d\u306b\u4f7f\u3048\u308b\u85ac\u306e\u73fe\u72b6-25\">\u8102\u80aa\u809d\u306b\u4f7f\u3048\u308b\u85ac\u306e\u73fe\u72b6<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u9577\u3089\u304fMASLD\u306b\u5bfe\u3057\u3066\u306f\u3001\u4fdd\u967a\u9069\u7528\u306e\u6c7a\u5b9a\u7684\u306a\u85ac\u304c\u306a\u3044\u72b6\u614b\u304c\u7d9a\u3044\u3066\u304d\u307e\u3057\u305f\u3002\u30d3\u30bf\u30df\u30f3E\u306f\u975e\u7cd6\u5c3f\u75c5\u6027\u306eMASH\u3067\u308f\u305a\u304b\u306a\u52b9\u679c\u304c\u5831\u544a\u3055\u308c\u3001\u30d4\u30aa\u30b0\u30ea\u30bf\u30be\u30f3\uff08\u7cd6\u5c3f\u75c5\u85ac\uff09\u306f\u708e\u75c7\u306e\u6539\u5584\u304c\u898b\u3089\u308c\u308b\u3082\u306e\u306e\u4f53\u91cd\u5897\u52a0\u306a\u3069\u306e\u526f\u4f5c\u7528\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2024\u5e74\u306b\u7c73\u56fd\u3067\u521d\u3081\u3066\u3001MASH\uff08\u4e2d\u7b49\u5ea6\u301c\u9032\u884c\u3057\u305f\u7dda\u7dad\u5316\u3092\u4f34\u3046\u975e\u809d\u786c\u5909MASH\uff09\u306b\u5bfe\u3059\u308b\u5c02\u9580\u85ac\u3068\u3057\u3066\u30ec\u30b9\u30e1\u30c1\u30ed\u30e0\u304c\u627f\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u308c\u306f\u5927\u304d\u306a\u524d\u9032\u3067\u3059\u304c\u3001\u7b2c3\u76f8\u8a66\u9a13\u306e\u30c7\u30fc\u30bf\u3067\u306f\u3001\u7d44\u7e54\u5b66\u7684\u6539\u5584\u306e\u57fa\u6e96\u3092\u6e80\u305f\u3057\u305f\u60a3\u8005\u69d8\u306f\u6cbb\u7642\u7fa4\u306e\u7d0425\u301c30%\u306b\u3068\u3069\u307e\u3063\u3066\u3044\u307e\u3059\u3002\u6b8b\u308a\u306e\u5927\u591a\u6570\u3067\u306f\u3001\u5c11\u306a\u304f\u3068\u3082\u8a66\u9a13\u3067\u8a55\u4fa1\u3055\u308c\u305f\u671f\u9593\u3068\u7528\u91cf\u306e\u7bc4\u56f2\u3067\u306f\u660e\u78ba\u306a\u6539\u5584\u304c\u898b\u3089\u308c\u306a\u304b\u3063\u305f\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">GLP-1\u53d7\u5bb9\u4f53\u4f5c\u52d5\u85ac\uff08\u30bb\u30de\u30b0\u30eb\u30c1\u30c9\u306a\u3069\u3001\u3082\u3068\u3082\u3068\u7cd6\u5c3f\u75c5\u30fb\u80a5\u6e80\u6cbb\u7642\u85ac\uff09\u3082\u3001\u6e1b\u91cf\u52b9\u679c\u3068\u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027\u6539\u5584\u3092\u4ecb\u3057\u3066\u8102\u80aa\u809d\u306b\u5bfe\u3059\u308b\u6709\u52b9\u6027\u304c\u691c\u8a0e\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u3053\u308c\u3089\u306e\u85ac\u5264\u3082\u542b\u3081\u3066\u3001\u73fe\u5728\u4fdd\u967a\u9069\u7528\u3055\u308c\u308b\u6cbb\u7642\u306e\u591a\u304f\u306f\u300c\u8102\u80aa\u306e\u84c4\u7a4d\u3084\u4ee3\u8b1d\u7570\u5e38\u300d\u3068\u3044\u3046\u4e0a\u6d41\u306e\u8981\u56e0\u306b\u50cd\u304d\u304b\u3051\u308b\u3082\u306e\u3067\u3042\u308a\u3001\u3059\u3067\u306b\u6d3b\u6027\u5316\u3057\u305f\u809d\u661f\u7d30\u80de\u3084\u6162\u6027\u708e\u75c7\u306e\u5834\u305d\u306e\u3082\u306e\u3092\u76f4\u63a5\u9759\u3081\u308b\u30a2\u30d7\u30ed\u30fc\u30c1\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u3053\u3053\u306b\u3001\u518d\u751f\u533b\u7642\u304c\u7814\u7a76\u3055\u308c\u3066\u304d\u305f\u7406\u7531\u304c\u3042\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-how-stem-cell-therapy-targets-fatty-liver-disease-three-biological-mechanisms-33\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u8102\u80aa\u809d\u306b\u5bfe\u3059\u308b\u5e79\u7d30\u80de\u6cbb\u7642\u3067\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u81e8\u5e8a\u30c7\u30fc\u30bf<\/mark><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"800\" height=\"390\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/Article-image-4.webp\" alt=\"\u8102\u80aa\u809d\u75be\u60a3\u306b\u5bfe\u3059\u308b\u9593\u8449\u7cfb\u5e79\u7d30\u80de\u7642\u6cd5\u306e3\u3064\u306e\u4f5c\u7528\u6a5f\u5e8f\uff08\u6297\u708e\u75c7\u4f5c\u7528\u3001\u6297\u7dda\u7dad\u5316\u4f5c\u7528\u3001\u809d\u7d30\u80de\u30b5\u30dd\u30fc\u30c8\uff09\u3092\u793a\u3059\u56f3\" class=\"wp-image-24746\" style=\"aspect-ratio:2.0460657773937463;width:670px;height:auto\" srcset=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/Article-image-4.webp 800w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/Article-image-4-300x146.webp 300w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/Article-image-4-768x374.webp 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption class=\"wp-element-caption\">\u9593\u8449\u7cfb\u5e79\u7d30\u80de\u306f\u3001\u5f93\u6765\u306e\u85ac\u5264\u3067\u306f\u540c\u6642\u306b\u4f5c\u7528\u3057\u306a\u30443\u3064\u306e\u91cd\u8907\u3059\u308b\u7d4c\u8def\u3092\u4ecb\u3057\u3066\u8102\u80aa\u809d\u75be\u60a3\u306b\u4f5c\u7528\u3059\u308b\u3002<\/figcaption><\/figure>\n<\/div>\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-calming-liver-inflammation-in-fatty-liver-disease-34\">\u809d\u75be\u60a3\u3092\u5bfe\u8c61\u3068\u3057\u305f\u4e3b\u306a\u81e8\u5e8a\u8a66\u9a13<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u3053\u306f\u6b63\u76f4\u306b\u66f8\u304f\u3079\u304d\u90e8\u5206\u3067\u3059\u3002MASLD\u306e\u60a3\u8005\u69d8\u3060\u3051\u3092\u5bfe\u8c61\u3068\u3057\u305f\u5927\u898f\u6a21\u306a\u7b2c3\u76f8\u7121\u4f5c\u70ba\u5316\u6bd4\u8f03\u8a66\u9a13\u306f\u3001\u73fe\u6642\u70b9\u3067\u306f\u307e\u3060\u767a\u8868\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002\u4e00\u65b9\u3067\u3001\u809d\u786c\u5909\u3084\u809d\u4e0d\u5168\u3068\u3044\u3063\u305f\u3001\u3088\u308a\u9032\u884c\u3057\u305f\u809d\u75be\u60a3\u3092\u5bfe\u8c61\u3068\u3057\u305fMSC\u6cbb\u7642\u306e\u81e8\u5e8a\u8a66\u9a13\u306f\u304b\u306a\u308a\u306e\u6570\u304c\u7a4d\u307f\u91cd\u306a\u3063\u3066\u304d\u3066\u304a\u308a\u3001\u3053\u3053\u304b\u3089\u5f97\u3089\u308c\u308b\u793a\u5506\u306f\u8102\u80aa\u809d\u306e\u6cbb\u7642\u3092\u8003\u3048\u308b\u4e0a\u3067\u3082\u6709\u7528\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Lin\u3089\u304c2017\u5e74\u306bHepatology\u8a8c\u306b\u767a\u8868\u3057\u305f\u30e9\u30f3\u30c0\u30e0\u5316\u6bd4\u8f03\u8a66\u9a13\u3067\u306f\u3001B\u578b\u809d\u708e\u30a6\u30a4\u30eb\u30b9\u95a2\u9023\u306e\u6025\u6027\u6162\u6027\u809d\u4e0d\u5168\u306e\u60a3\u8005\u69d8110\u540d\u304c\u5bfe\u8c61\u3068\u306a\u308a\u307e\u3057\u305f\u3002\u4ed6\u5bb6\u9aa8\u9ac4\u7531\u6765MSC\u306e\u70b9\u6ef4\u6295\u4e0e\u3092\u53d7\u3051\u305f\u7fa4\u306f\u3001\u5bfe\u7167\u7fa4\u3068\u6bd4\u8f03\u3057\u306624\u9031\u6642\u70b9\u3067\u306e\u751f\u5b58\u7387\u304c\u6709\u610f\u306b\u6539\u5584\u3057\u3001\u809d\u75be\u60a3\u91cd\u75c7\u5ea6\u306e\u6307\u6a19\u3067\u3042\u308bMELD\u30b9\u30b3\u30a2\u3082\u6709\u610f\u306b\u6539\u5584\u3057\u307e\u3057\u305f\u3002\u91cd\u7be4\u306a\u526f\u4f5c\u7528\u306f\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Suk\u3089\u304c2016\u5e74\u306bHepatology\u8a8c\u306b\u767a\u8868\u3057\u305f\u7b2c2\u76f8\u8a66\u9a13\u3067\u306f\u3001\u30a2\u30eb\u30b3\u30fc\u30eb\u6027\u809d\u786c\u5909\u306e\u60a3\u8005\u69d8\u306b\u5bfe\u3059\u308b\u81ea\u5bb6\u9aa8\u9ac4\u7531\u6765MSC\u306e\u6cbb\u7642\u52b9\u679c\u304c\u691c\u8a0e\u3055\u308c\u307e\u3057\u305f\u300224\u9031\u5f8c\u306e\u809d\u751f\u691c\u3067\u3001\u7dda\u7dad\u5316\u30b9\u30b3\u30a2\u306e\u7d44\u7e54\u5b66\u7684\u6539\u5584\u304c\u78ba\u8a8d\u3055\u308c\u307e\u3057\u305f\u3002\u3053\u308c\u306f\u3001\u4eba\u9593\u306b\u304a\u3044\u3066\u5e79\u7d30\u80de\u6cbb\u7642\u306b\u3088\u3063\u3066\u7dda\u7dad\u5316\u306e\u6539\u5584\u304c\u7d44\u7e54\u5b66\u7684\u30ec\u30d9\u30eb\u3067\u793a\u3055\u308c\u305f\u3001\u521d\u671f\u306e\u91cd\u8981\u306a\u7814\u7a76\u306e\u4e00\u3064\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Wang\u3089\u306b\u3088\u308b\u3068Primary Biliary Cirrhosis\uff08\u539f\u767a\u6027\u80c6\u6c41\u6027\u80c6\u7ba1\u708e\uff09\u60a3\u8005\u69d8\u3078\u306e\u81cd\u5e2f\u7531\u6765MSC\u6cbb\u7642\u306e\u8a66\u9a13\u3067\u306f\u3001ALT\u3001AST\u3001\u03b3-GT\u3068\u3044\u3063\u305f\u809d\u9175\u7d20\u306e\u4f4e\u4e0b\u304c\u89b3\u5bdf\u3055\u308c\u3001\u660e\u78ba\u306a\u526f\u4f5c\u7528\u306f\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">MASLD\u305d\u306e\u3082\u306e\u306b\u5bfe\u3059\u308b\u30d2\u30c8\u3067\u306e\u81e8\u5e8a\u30c7\u30fc\u30bf\u306f\u73fe\u6642\u70b9\u3067\u306f\u9650\u5b9a\u7684\u3067\u3001\u52d5\u7269\u30e2\u30c7\u30eb\uff08\u8102\u80aa\u809d\u306e\u30de\u30a6\u30b9\u306bMSC\u3092\u6295\u4e0e\u3057\u305f\u5b9f\u9a13\uff09\u304c\u4e2d\u5fc3\u3067\u3059\u3002\u3053\u308c\u3089\u306e\u52d5\u7269\u5b9f\u9a13\u3067\u306f\u3001\u809d\u5185\u306e\u8102\u80aa\u542b\u6709\u91cf\u306e\u6e1b\u5c11\u3001\u708e\u75c7\u7d30\u80de\u306e\u6d78\u6f64\u306e\u6e1b\u5c11\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u611f\u53d7\u6027\u306e\u6539\u5584\u306a\u3069\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002MASLD\u5358\u72ec\u306b\u5bfe\u3059\u308b\u5927\u898f\u6a21\u306a\u30d2\u30c8RCT\u306f\u8907\u6570\u306e\u56fd\u3067\u9032\u884c\u4e2d\u3067\u3001\u3053\u308c\u304b\u3089\u306e\u6570\u5e74\u3067\u7d50\u679c\u304c\u51fa\u3066\u304f\u308b\u6bb5\u968e\u3067\u3059\u3002<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-\u8102\u80aa\u809d\u3067\u671f\u5f85\u3067\u304d\u308b\u73fe\u5b9f\u7684\u306a\u6539\u5584\u5e45-42\">\u8102\u80aa\u809d\u3067\u671f\u5f85\u3067\u304d\u308b\u73fe\u5b9f\u7684\u306a\u6539\u5584\u5e45<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u8907\u6570\u306e\u81e8\u5e8a\u8a66\u9a13\u3092\u7dcf\u5408\u3059\u308b\u3068\u3001\u594f\u52b9\u3059\u308b\u60a3\u8005\u69d8\u306b\u304a\u3044\u3066\u4ee5\u4e0b\u306e\u3088\u3046\u306a\u5909\u5316\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002ALT\u30fbAST\u306b\u3064\u3044\u3066\u306f\u6cbb\u764212\u301c24\u9031\u6642\u70b9\u306725\u301c45%\u7a0b\u5ea6\u306e\u4f4e\u4e0b\u3001FibroScan\u306e\u809d\u786c\u5ea6\u306b\u3064\u3044\u3066\u306f\u5143\u306e\u6570\u5024\u304c\u9ad8\u3044\u65b9\u30671\u301c3 kPa\u7a0b\u5ea6\u306e\u4f4e\u4e0b\u3001\u9032\u884c\u3057\u305f\u809d\u75be\u60a3\u306e\u5834\u5408\u306eMELD\u30b9\u30b3\u30a2\u3067\u306f2\u301c4\u30dd\u30a4\u30f3\u30c8\u306e\u6539\u5584\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5177\u4f53\u7684\u306b\u4f55\u3092\u610f\u5473\u3059\u308b\u304b\u3092\u8aac\u660e\u3057\u307e\u3059\u3002ALT\u304c90 IU\/L\u3042\u3063\u305f\u65b9\u304c50\u301c60\u306b\u4e0b\u304c\u308b\u306e\u306f\u3001\u6b63\u5e38\u5316\u307e\u3067\u306f\u81f3\u3089\u306a\u3044\u3082\u306e\u306e\u3001\u751f\u7269\u5b66\u7684\u306b\u306f\u610f\u5473\u306e\u3042\u308b\u5909\u5316\u3067\u3059\u3002FibroScan\u30679 kPa\uff08\u7dda\u7dad\u5316\u304c\u9032\u3093\u3060\u72b6\u614b\uff09\u3060\u3063\u305f\u65b9\u304c6\u301c7 kPa\uff08\u4e00\u6bb5\u968e\u524d\u306e\u30b9\u30c6\u30fc\u30b8\uff09\u306b\u4e0b\u304c\u308b\u306e\u306f\u3001\u6570\u5b57\u4e0a\u306f\u300c\u9032\u884c\u304c\u5f8c\u9000\u3057\u305f\u300d\u3068\u8a55\u4fa1\u3067\u304d\u308b\u5909\u5316\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u305f\u3060\u3057\u3001\u3053\u3053\u3067\u3082\u6b63\u76f4\u306b\u304a\u4f1d\u3048\u3057\u3066\u304a\u304d\u305f\u3044\u306e\u306f\u3001\u300c\u5168\u54e1\u306b\u52b9\u304f\u308f\u3051\u3067\u306f\u306a\u3044\u300d\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002\u8a66\u9a13\u30c7\u30fc\u30bf\u3068\u79c1\u305f\u3061\u306e\u81e8\u5e8a\u7d4c\u9a13\u3092\u5408\u308f\u305b\u308b\u3068\u3001\u3042\u308b\u7a0b\u5ea6\u306e\u6539\u5584\u304c\u898b\u3089\u308c\u308b\u65b9\u306f\u6982\u306d30\u301c50%\u7a0b\u5ea6\u3002\u6b8b\u308a\u306e\u65b9\u306f\u5909\u5316\u304c\u4e4f\u3057\u3044\u304b\u3001\u307b\u3068\u3093\u3069\u898b\u3089\u308c\u307e\u305b\u3093\u3002\u8ab0\u304c\u594f\u52b9\u3059\u308b\u304b\u3092\u6cbb\u7642\u524d\u306b\u78ba\u5b9f\u306b\u4e88\u6e2c\u3059\u308b\u624b\u6bb5\u306f\u3001\u73fe\u6642\u70b9\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u3053\u306e\u6570\u5b57\u306f\u3001\u6cbb\u7642\u3092\u691c\u8a0e\u3059\u308b\u524d\u306b\u305c\u3072\u77e5\u3063\u3066\u304a\u3044\u3066\u307b\u3057\u3044\u73fe\u5b9f\u3067\u3059\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-what-the-clinical-data-shows-about-stem-cell-therapy-for-fatty-liver-disease-48\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u8102\u80aa\u809d\u306b\u5bfe\u3059\u308b\u5e79\u7d30\u80de\u7642\u6cd5\u306b\u95a2\u3059\u308b\u81e8\u5e8a\u30c7\u30fc\u30bf\u304c\u793a\u3059\u3082\u306e<\/mark><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"800\" height=\"668\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/SCMC-Article-32.webp\" alt=\"\u767a\u8868\u3055\u308c\u305f\u81e8\u5e8a\u8a66\u9a13\u30c7\u30fc\u30bf\u306b\u57fa\u3065\u304d\u3001\u8102\u80aa\u809d\u75be\u60a3\u60a3\u8005\u306b\u304a\u3051\u308b\u9593\u8449\u7cfb\u5e79\u7d30\u80de\u6cbb\u7642\u5f8c\u306eALT\u304a\u3088\u3073AST\u809d\u9175\u7d20\u30ec\u30d9\u30eb\u306e\u4f4e\u4e0b\u3092\u793a\u3059\u68d2\u30b0\u30e9\u30d5\" class=\"wp-image-24745\" style=\"aspect-ratio:1.2519970004238532;width:532px;height:auto\" srcset=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/SCMC-Article-32.webp 800w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/SCMC-Article-32-300x251.webp 300w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/SCMC-Article-32-768x641.webp 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption class=\"wp-element-caption\">\u809d\u75be\u60a3\u306b\u5bfe\u3059\u308bMSC\u7642\u6cd5\u306b\u95a2\u3059\u308b\u65e2\u767a\u8868\u306e\u81e8\u5e8a\u8a66\u9a13\u3067\u306f\u3001\u809d\u81d3\u306e\u708e\u75c7\u30de\u30fc\u30ab\u30fc\u3067\u3042\u308bALT\u304a\u3088\u3073AST\u9175\u7d20\u306e\u6e1b\u5c11\u304c12\uff5e24\u9031\u3067\u89b3\u5bdf\u3055\u308c\u3066\u3044\u308b\u3002<br>\u51fa\u5178\uff1aSuk\u3089\uff082016\uff09\u304a\u3088\u3073Lin\u3089\uff082017\uff09\u3092\u542b\u3080\u81e8\u5e8a\u8a66\u9a13\u30c7\u30fc\u30bf\u306e\u96c6\u8a08\u3002<\/figcaption><\/figure>\n<\/div>\n\n\n<h4 class=\"wp-block-heading\" id=\"aioseo-key-trials-of-msc-therapy-in-liver-disease-and-fatty-liver-disease-49\">\u809d\u75be\u60a3\u304a\u3088\u3073\u8102\u80aa\u809d\u75be\u60a3\u306b\u304a\u3051\u308bMSC\u7642\u6cd5\u306b\u95a2\u3059\u308b\u4e3b\u8981\u306a\u81e8\u5e8a\u8a66\u9a13<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">\u809d\u75be\u60a3\u306b\u304a\u3051\u308b\u9593\u8449\u7cfb\u5e79\u7d30\u80de\u7642\u6cd5\u306e\u30a8\u30d3\u30c7\u30f3\u30b9\u306f\u3001\u591a\u304f\u306e\u60a3\u8005\u3055\u3093\u304c\u8a8d\u8b58\u3057\u3066\u3044\u308b\u4ee5\u4e0a\u306b\u5145\u5b9f\u3057\u3066\u3044\u307e\u3059\u3002\u305f\u3060\u3057\u3001\u767a\u8868\u3055\u308c\u3066\u3044\u308b\u6700\u5927\u898f\u6a21\u306e\u81e8\u5e8a\u8a66\u9a13\u306f\u3001\u65e9\u671f\u306eMASLD\uff08B\u578b\u809d\u708e\u95a2\u9023\u6025\u6027\u6162\u6027\u809d\u4e0d\u5168\uff09\u3067\u306f\u306a\u304f\u3001\u809d\u786c\u5909\u3084\u6025\u6027\u5897\u60aa\u578b\u6162\u6027\u809d\u4e0d\u5168\u306b\u7126\u70b9\u3092\u5f53\u3066\u305f\u3082\u306e\u304c\u307b\u3068\u3093\u3069\u3067\u3059\u3002\u3053\u306e\u70b9\u306b\u3064\u3044\u3066\u306f\u3001\u6b63\u76f4\u306b\u3054\u8aac\u660e\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2017\u5e74\u306bHepatology\u8a8c\u306b\u63b2\u8f09\u3055\u308c\u305fLin\u3089\u306b\u3088\u308b\u7121\u4f5c\u70ba\u5316\u6bd4\u8f03\u8a66\u9a13\u3067\u306f\u3001B\u578b\u809d\u708e\u30a6\u30a4\u30eb\u30b9\u95a2\u9023\u6025\u6027\u5897\u60aa\u578b\u6162\u6027\u809d\u4e0d\u5168\u60a3\u8005110\u540d\u3092\u5bfe\u8c61\u306b\u3001\u540c\u7a2e\u9aa8\u9ac4\u7531\u6765\u9593\u8449\u7cfb\u5e79\u7d30\u80de\uff08MSC\uff09\u306e\u6295\u4e0e\u52b9\u679c\u3092\u8a55\u4fa1\u3057\u307e\u3057\u305f\u300224\u9031\u5f8c\u3001MSC\u7642\u6cd5\u3092\u53d7\u3051\u305f\u7fa4\u306f\u5bfe\u7167\u7fa4\u3068\u6bd4\u8f03\u3057\u3066\u751f\u5b58\u7387\u304c\u6709\u610f\u306b\u6539\u5584\u3057\u3001\u809d\u75be\u60a3\u306e\u91cd\u75c7\u5ea6\u3092\u793a\u3059\u6a19\u6e96\u5316\u6307\u6a19\u3067\u3042\u308bMELD\u30b9\u30b3\u30a2\u3082\u4f4e\u4e0b\u3057\u307e\u3057\u305f\u3002\u3053\u306e\u8a66\u9a13\u306b\u3088\u308a\u3001\u540c\u7a2eMSC\u306f\u91cd\u75c7\u60a3\u8005\u306b\u304a\u3044\u3066\u5b89\u5168\u3067\u3042\u308a\u3001\u6e2c\u5b9a\u53ef\u80fd\u306a\u81e8\u5e8a\u7684\u52b9\u679c\u3092\u3082\u305f\u3089\u3059\u3053\u3068\u304c\u5b9f\u8a3c\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2016\u5e74\u306bHepatology\u8a8c\u306b\u63b2\u8f09\u3055\u308c\u305fSuk\u3089\u306b\u3088\u308b\u7b2c2\u76f8\u81e8\u5e8a\u8a66\u9a13\u3067\u306f\u3001\u30a2\u30eb\u30b3\u30fc\u30eb\u6027\u809d\u786c\u5909\u60a3\u8005\u3092\u5bfe\u8c61\u306b\u3001\u81ea\u5df1\u9aa8\u9ac4\u7531\u6765\u9593\u8449\u7cfb\u5e79\u7d30\u80de\uff08MSC\uff09\u306e\u52b9\u679c\u304c\u691c\u8a0e\u3055\u308c\u307e\u3057\u305f\u3002\u6cbb\u7642\u3092\u53d7\u3051\u305f\u60a3\u8005\u306f\u300124\u9031\u9593\u5f8c\u306e\u751f\u691c\u3067\u809d\u7dda\u7dad\u5316\u306e\u7d44\u7e54\u5b66\u7684\u6539\u5584\u3092\u793a\u3057\u3001\u7d44\u7e54\u5206\u6790\u3067\u306f\u30b3\u30e9\u30fc\u30b2\u30f3\u542b\u6709\u91cf\u306e\u6e1b\u5c11\u304c\u8a8d\u3081\u3089\u308c\u307e\u3057\u305f\u3002\u3053\u308c\u306f\u3001\u30d2\u30c8\u306b\u304a\u3044\u3066MSC\u7642\u6cd5\u5f8c\u306b\u751f\u691c\u3067\u7dda\u7dad\u5316\u306e\u6539\u5584\u304c\u8a8d\u3081\u3089\u308c\u305f\u6700\u521d\u306e\u7814\u7a76\u306e\u4e00\u3064\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3044\u304f\u3064\u304b\u306e\u5c0f\u898f\u6a21\u306a\u7814\u7a76\u3084\u30d1\u30a4\u30ed\u30c3\u30c8\u8a66\u9a13\u3067\u306f\u3001\u81cd\u5e2f\u7531\u6765MSC\u304c\u7279\u306b\u691c\u8a0e\u3055\u308c\u3066\u3044\u307e\u3059\u3002Wang\u3089\u306f\u3001\u539f\u767a\u6027\u80c6\u6c41\u6027\u809d\u786c\u5909\u60a3\u8005\u306b\u5bfe\u3059\u308b\u81cd\u5e2f\u7531\u6765MSC\u7642\u6cd5\u306b\u3088\u308a\u3001ALT\u3001AST\u3001\u03b3-GT\u9175\u7d20\u5024\u306e\u4f4e\u4e0b\u3068\u75c7\u72b6\u306e\u6539\u5584\u304c\u8a8d\u3081\u3089\u308c\u3001\u8ffd\u8de1\u671f\u9593\u4e2d\u306b\u91cd\u5927\u306a\u6709\u5bb3\u4e8b\u8c61\u306f\u8a8d\u3081\u3089\u308c\u306a\u304b\u3063\u305f\u3068\u5831\u544a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p 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style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-what-realistic-improvement-looks-like-after-fatty-liver-disease-treatment-56\">\u8102\u80aa\u809d\u306e\u6162\u6027\u708e\u75c7\u3092\u6291\u3048\u308b\u50cd\u304d<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u9593\u8449\u7cfb\u5e79\u7d30\u80de\uff08MSC\uff09\u306f\u3001\u85ac\u306e\u3088\u3046\u306b\u300c\u7279\u5b9a\u306e\u5206\u5b50\u3092\u30d6\u30ed\u30c3\u30af\u3059\u308b\u300d\u7269\u8cea\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u514d\u75ab\u7d30\u80de\u305d\u306e\u3082\u306e\u306b\u5bfe\u3057\u3066\u8a71\u3057\u304b\u3051\u308b\u7d30\u80de\u3001\u3068\u8a00\u3063\u305f\u307b\u3046\u304c\u611f\u899a\u7684\u306b\u306f\u8fd1\u3044\u3067\u3059\u3002<\/p>\n\n\n\n<p 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data-wp-context=\"{ &quot;id&quot;: &quot;accordion-item-3&quot;, &quot;openByDefault&quot;: false }\" data-wp-init=\"callbacks.initAccordionItems\" data-wp-on-window--hashchange=\"callbacks.hashChange\" class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h4 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-3-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" id=\"accordion-item-3\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span class=\"wp-block-accordion-heading__toggle-title\">\u8102\u80aa\u809d\u306b\u5bfe\u3059\u308b\u5e79\u7d30\u80de\u6cbb\u7642\u306e\u52b9\u679c\u306f\u3069\u306e\u304f\u3089\u3044\u6301\u7d9a\u3057\u307e\u3059\u304b\uff1f<\/span><span class=\"wp-block-accordion-heading__toggle-icon\" aria-hidden=\"true\">+<\/span><\/button><\/h4>\n\n\n\n<div aria-labelledby=\"accordion-item-3\" data-wp-bind--hidden=\"state.isHidden\" 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aria-labelledby=\"accordion-item-4\" data-wp-bind--hidden=\"state.isHidden\" data-wp-on--beforematch=\"actions.handleBeforeMatch\" id=\"accordion-item-4-panel\" role=\"region\" class=\"wp-block-accordion-panel is-layout-flow wp-block-accordion-panel-is-layout-flow\">\n<p class=\"wp-block-paragraph\">\u6b63\u76f4\u306a\u3068\u3053\u308d\u3001\u809d\u786c\u5909\u306e\u9032\u884c\u6bb5\u968e\u306b\u3088\u3063\u3066\u7b54\u3048\u306f\u7570\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p 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&quot;autoclose&quot;: false, &quot;accordionItems&quot;: [] }\" data-wp-interactive=\"core\/accordion\" role=\"group\" class=\"wp-block-accordion is-layout-flow wp-block-accordion-is-layout-flow\">\n<div data-wp-class--is-open=\"state.isOpen\" data-wp-context=\"{ &quot;id&quot;: &quot;accordion-item-5&quot;, &quot;openByDefault&quot;: false }\" data-wp-init=\"callbacks.initAccordionItems\" data-wp-on-window--hashchange=\"callbacks.hashChange\" class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h4 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-5-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" id=\"accordion-item-5\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span 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style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-references-158\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u53c2\u8003\u6587\u732e<\/mark><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Younossi ZM, Koenig AB, Abdelatif D, Fazel Y, Henry L, Wymer M. &#8220;Global epidemiology of nonalcoholic fatty liver disease \u2014 meta-analytic assessment of prevalence, incidence, and outcomes.&#8221; Hepatology. 2016;64(1):73\u201384. <a href=\"https:\/\/doi.org\/10.1002\/hep.28431\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1002\/hep.28431<\/a><\/li>\n\n\n\n<li>Rinella ME, Lazarus JV, Ratziu V, et al. &#8220;A multisociety Delphi consensus statement on new fatty liver disease nomenclature.&#8221; Hepatology. 2023;78(6):1966\u20131986. <a href=\"https:\/\/doi.org\/10.1097\/HEP.0000000000000520\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1097\/HEP.0000000000000520<\/a><\/li>\n\n\n\n<li>Suk KT, Yoon JH, Kim MY, et al. &#8220;Transplantation with autologous bone marrow-derived mesenchymal stem cells for alcoholic cirrhosis: Phase 2 trial.&#8221; Hepatology. 2016;64(6):2185\u20132197. <a href=\"https:\/\/doi.org\/10.1002\/hep.28693\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1002\/hep.28693<\/a><\/li>\n\n\n\n<li>Lin BL, Chen JF, Qiu WH, et al. &#8220;Allogeneic bone marrow-derived mesenchymal stromal cells for hepatitis B virus-related acute-on-chronic liver failure: A randomized controlled trial.&#8221; Hepatology. 2017;66(1):209\u2013219. <a href=\"https:\/\/doi.org\/10.1002\/hep.29189\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1002\/hep.29189<\/a><\/li>\n\n\n\n<li>Wang L, Han Q, Chen H, et al. &#8220;Allogeneic bone marrow mesenchymal stem cell transplantation in patients with UDCA-resistant primary biliary cirrhosis.&#8221; Stem Cells and Development. 2014;23(20):2482\u20132489. <a href=\"https:\/\/doi.org\/10.1089\/scd.2013.0500\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1089\/scd.2013.0500<\/a><\/li>\n\n\n\n<li>Harrison SA, Bedossa P, Guy CD, et al. &#8220;A Phase 3, Randomized, Controlled Trial of Resmetirom in NASH with Liver Fibrosis (MAESTRO-NASH).&#8221; New England Journal of Medicine. 2024;390(6):497\u2013509. <a href=\"https:\/\/doi.org\/10.1056\/NEJMoa2309000\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1056\/NEJMoa2309000<\/a><\/li>\n<\/ol>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\t\t<div data-elementor-type=\"section\" data-elementor-id=\"21873\" class=\"elementor elementor-21873\" data-elementor-post-type=\"elementor_library\">\n\t\t\t        <section class=\"elementor-section elementor-top-section elementor-element elementor-element-a6ebaad elementor-section-boxed 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