{"id":24610,"date":"2026-04-27T14:05:42","date_gmt":"2026-04-27T06:05:42","guid":{"rendered":"https:\/\/stemcell-malaysia.com\/?page_id=24610"},"modified":"2026-04-27T14:05:43","modified_gmt":"2026-04-27T06:05:43","slug":"mild-cognitive-impairment","status":"publish","type":"page","link":"https:\/\/stemcell-malaysia.com\/ja\/conditions\/mild-cognitive-impairment\/","title":{"rendered":"\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\u5e79\u7d30\u80de\u6cbb\u7642 | \u8a8d\u77e5\u6a5f\u80fd\u4f4e\u4e0b\u306f\u8a8d\u77e5\u75c7\u306b\u306a\u308b\u524d\u306b\u9045\u3089\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u304b\uff1f"},"content":{"rendered":"\n<h1 class=\"wp-block-heading has-text-align-center\">\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\u5e79\u7d30\u80de\u6cbb\u7642 | \u8a8d\u77e5\u6a5f\u80fd\u4f4e\u4e0b\u306f\u8a8d\u77e5\u75c7\u306b\u306a\u308b\u524d\u306b\u9045\u3089\u305b\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u304b\uff1f<\/h1>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img fetchpriority=\"high\" decoding=\"async\" width=\"800\" height=\"450\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/pexels-googledeepmind-17483868.webp\" alt=\"\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\u306b\u5bfe\u3059\u308b\u5e79\u7d30\u80de\u7642\u6cd5\u3067\u6a19\u7684\u3068\u3055\u308c\u308b\u8907\u96d1\u306a\u795e\u7d4c\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u3092\u8868\u3059\u3001\u7d2b\u8272\u306e\u30ef\u30a4\u30e4\u30fc\u30d5\u30ec\u30fc\u30e0\u3067\u63cf\u304b\u308c\u305f\u672a\u6765\u7684\u306a3D\u30c7\u30b8\u30bf\u30eb\u30a4\u30e9\u30b9\u30c8\u3002\" class=\"wp-image-24574\" style=\"width:592px\" srcset=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/pexels-googledeepmind-17483868.webp 800w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/pexels-googledeepmind-17483868-300x169.webp 300w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/pexels-googledeepmind-17483868-768x432.webp 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption class=\"wp-element-caption\">\u8133\u306e\u7cbe\u5de7\u306a\u795e\u7d4c\u7d4c\u8def\u306e\u62bd\u8c61\u7684\u306a\u8868\u73fe\u3002\u5e79\u7d30\u80de\u6cbb\u7642\u306f\u3001\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\u306e\u9032\u884c\u3092\u9045\u3089\u305b\u308b\u305f\u3081\u306b\u3001\u3053\u308c\u3089\u3092\u4fdd\u8b77\u3057\u30b5\u30dd\u30fc\u30c8\u3059\u308b\u3053\u3068\u3092\u76ee\u6307\u3057\u3066\u3044\u307e\u3059\u3002<\/figcaption><\/figure>\n<\/div>\n\n\n<p class=\"wp-block-paragraph\">\u4ee5\u524d\u306f\u540d\u524d\u3092\u805e\u3044\u305f\u77ac\u9593\u306b\u899a\u3048\u3089\u308c\u305f\u306e\u306b\u3001\u4eca\u306f\u7a7a\u767d\u304c\u3067\u304d\u3001\u304b\u3064\u3066\u306e\u3088\u3046\u306b\u7d20\u65e9\u304f\u601d\u3044\u51fa\u3059\u3053\u3068\u304c\u3067\u304d\u306a\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6697\u8a18\u3057\u305f\u3068\u78ba\u4fe1\u3057\u3066\u3044\u305f\u8cb7\u3044\u7269\u30ea\u30b9\u30c8\u306f\u3001\u304a\u5e97\u306b\u7740\u304f\u9803\u306b\u306f\u5fd8\u308c\u3066\u3044\u307e\u3059\u3002\u5148\u9031\u4e88\u7d04\u3057\u305f\u4f1a\u8b70\u304c\u30ab\u30ec\u30f3\u30c0\u30fc\u306b\u8868\u793a\u3055\u308c\u3066\u3044\u3066\u3082\u3001\u4e88\u5b9a\u3092\u5165\u308c\u305f\u8a18\u61b6\u304c\u307e\u3063\u305f\u304f\u3042\u308a\u307e\u305b\u3093\u3002\u8a71\u306e\u9014\u4e2d\u3067\u3001\u304b\u3064\u3066\u306f\u82e6\u52b4\u305b\u305a\u306b\u601d\u3044\u6d6e\u304b\u3093\u3060\u8a00\u8449\u304c\u51fa\u3066\u304f\u308b\u306e\u3092\u5f85\u3063\u3066\u3044\u308b\u81ea\u5206\u306b\u6c17\u3065\u304d\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u3088\u3046\u306a\u77ac\u9593\u306f\u3001\u6700\u521d\u306f\u305f\u307e\u306b\u3057\u304b\u8d77\u3053\u3089\u306a\u304b\u3063\u305f\u304b\u3082\u3057\u308c\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u3001\u3053\u306e\u8a18\u4e8b\u3092\u8aad\u3093\u3067\u3044\u308b\u306a\u3089\u3001\u304a\u305d\u3089\u304f\u3082\u3046\u300c\u305f\u307e\u306b\u300d\u306e\u3053\u3068\u3060\u3068\u306f\u611f\u3058\u3066\u3044\u306a\u3044\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u533b\u5e2b\u304b\u3089\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\uff08Mild Cognitive Impairment, MCI\uff09\u3068\u8a3a\u65ad\u3055\u308c\u305f\u5834\u5408\u3001\u81e8\u5e8a\u7684\u306a\u6307\u5c0e\u304c\u307b\u3068\u3093\u3069\u306a\u3044\u8a3a\u65ad\u3092\u62b1\u3048\u3066\u751f\u6d3b\u3059\u308b\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002\u3082\u3063\u3068\u904b\u52d5\u3092\u3057\u3001\u8cea\u306e\u826f\u3044\u98df\u4e8b\u3092\u53d6\u308a\u3001\u982d\u3092\u50cd\u304b\u305b\u30011\u5e74\u5f8c\u306b\u307e\u305f\u6765\u3066\u304f\u3060\u3055\u3044\u3068\u8a00\u308f\u308c\u305f\u3053\u3068\u3067\u3057\u3087\u3046\u3002\u3057\u304b\u3057\u3001\u8133\u306e\u4e2d\u3067\u8d77\u304d\u3066\u3044\u308b\u9032\u884c\u3092\u9045\u3089\u305b\u308b\u305f\u3081\u306b\u3001\u7d4c\u904e\u89b3\u5bdf\u4ee5\u5916\u306b\u533b\u5b66\u304c\u5b9f\u969b\u306b\u4f55\u3092\u3057\u3066\u304f\u308c\u308b\u306e\u304b\u306b\u3064\u3044\u3066\u306f\u6559\u3048\u3089\u308c\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u4e16\u754c\u306e\u75be\u75c5\u8ca0\u62c5\u7814\u7a76\uff08Global Burden of Disease study\uff09\u306b\u3088\u308b\u3068\u30012019\u5e74\u6642\u70b9\u3067\u4e16\u754c\u4e2d\u3067\u7d046,880\u4e07\u4eba\u304cMCI\u3092\u62b1\u3048\u3066\u751f\u6d3b\u3057\u3066\u3044\u308b\u3068\u63a8\u5b9a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u3046\u3061\u3001\u6bce\u5e74\u7d0410\u301c15\uff05\u304c\u8a8d\u77e5\u75c7\u3078\u3068\u9032\u884c\u3057\u307e\u3059\u3002\u8a18\u61b6\u306b\u7126\u70b9\u3092\u5f53\u3066\u305f\u30b5\u30d6\u30bf\u30a4\u30d7\u3067\u3042\u308b\u5065\u5fd8\u578b\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\uff08Amnestic MCI\uff09\u306e\u60a3\u8005\u306e\u3046\u3061\u3001\u305d\u306e\u8ecc\u9053\u3092\u4f55\u3082\u5909\u3048\u306a\u3051\u308c\u3070\u3001\u7d04\u534a\u6570\u304c5\u5e74\u4ee5\u5185\u306b\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\uff08Alzheimer&#8217;s disease\uff09\u3092\u767a\u75c7\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\u306b\u5bfe\u3059\u308b\u5e79\u7d30\u80de\u6cbb\u7642\u306f\u3001\u73fe\u5728\u6d3b\u767a\u306b\u81e8\u5e8a\u7814\u7a76\u304c\u884c\u308f\u308c\u3066\u3044\u308b\u5206\u91ce\u3067\u3059\u3002\u3053\u308c\u306f\u6cbb\u7642\u6cd5\uff08\u5b8c\u6cbb\u3055\u305b\u308b\u3082\u306e\uff09\u3067\u306f\u306a\u304f\u3001\u79c1\u305f\u3061\u3082\u305d\u3046\u3067\u3042\u308b\u3068\u793a\u5506\u3059\u308b\u3064\u3082\u308a\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u3001\u751f\u7269\u5b66\u7684\u306b\u7b4b\u306e\u901a\u3063\u305f\u30a2\u30d7\u30ed\u30fc\u30c1\u3067\u3042\u308a\u3001\u67fb\u8aad\u6e08\u307f\u306e\u8a3c\u62e0\u304c\u5897\u3048\u3064\u3064\u3042\u308a\u307e\u3059\u3002\u305d\u3057\u3066\u3001\u307b\u3068\u3093\u3069\u306eMCI\u60a3\u8005\u306f\u3001\u7b54\u3048\u304c\u300c\u30ce\u30fc\u300d\u3067\u3042\u308b\u5834\u5408\u306b\u306f\u305d\u308c\u3092\u306f\u3063\u304d\u308a\u3068\u4f1d\u3048\u308b\u81e8\u5e8a\u30c1\u30fc\u30e0\u304b\u3089\u3001\u5177\u4f53\u7684\u306a\u6570\u5b57\u3092\u4ea4\u3048\u3066\u3053\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\u306b\u3064\u3044\u3066\u6b63\u76f4\u306b\u8b70\u8ad6\u3055\u308c\u305f\u7d4c\u9a13\u304c\u306a\u3044\u3067\u3057\u3087\u3046\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u79c1\u305f\u3061\u306f\u30de\u30ec\u30fc\u30b7\u30a2\u306b\u62e0\u70b9\u3092\u7f6e\u3044\u3066\u3044\u307e\u3059\u3002\u79c1\u305f\u3061\u306e\u30c1\u30fc\u30e0\u306f\u518d\u751f\u533b\u7642\u306b7\u5e74\u4ee5\u4e0a\u643a\u308f\u3063\u3066\u304a\u308a\u3001\u3055\u307e\u3056\u307e\u306a\u75be\u60a3\u306b\u308f\u305f\u3063\u3066\u540c\u7a2e\uff08\u30c9\u30ca\u30fc\u7531\u6765\uff09\u81cd\u5e2f\u9593\u8449\u7cfb\u5e79\u7d30\u80de\uff08Mesenchymal Stem Cells, MSCs\uff09\u3092\u4f7f\u7528\u3057\u3066200\u4eba\u4ee5\u4e0a\u306e\u60a3\u8005\u3092\u6cbb\u7642\u3057\u3066\u304d\u307e\u3057\u305f\u3002\u3053\u306e\u8a18\u4e8b\u3067\u306f\u3001\u81e8\u5e8a\u7684\u8a3c\u62e0\u304c\u793a\u3057\u3066\u3044\u308b\u3053\u3068\u3001\u793a\u3057\u3066\u3044\u306a\u3044\u3053\u3068\u3001\u305d\u3057\u3066\u3053\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\u306e\u73fe\u5b9f\u7684\u306a\u5019\u88dc\u8005\u3068\u306a\u308b\u306e\u306f\u8ab0\u304b\u3001\u306a\u3089\u306a\u3044\u306e\u306f\u8ab0\u304b\u3092\u63d0\u793a\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u76ee\u6b21<\/mark><\/h2>\n\n\n<div class=\"wp-block-aioseo-table-of-contents\"><ol><li><a class=\"aioseo-toc-item\" href=\"#aioseo-the-daily-reality-and-why-mild-cognitive-impairment-escapes-natural-repair-5\">\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\u306e\u9032\u884c\u4e2d\u3001\u8133\u306e\u5185\u90e8\u3067\u4f55\u304c\u8d77\u304d\u3066\u3044\u308b\u306e\u304b<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-the-gap-in-standard-care-for-mild-cognitive-impairment-27\">\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\u306b\u304a\u3051\u308b\u6a19\u6e96\u6cbb\u7642\u306e\u30ae\u30e3\u30c3\u30d7<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-what-the-clinical-evidence-shows-for-stem-cell-therapy-in-mci-40\">\u81e8\u5e8a\u7684\u8a3c\u62e0\u304cMCI\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u306b\u3064\u3044\u3066\u793a\u3057\u3066\u3044\u308b\u3053\u3068<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-how-stem-cells-address-the-biology-of-mild-cognitive-impairment-56\">\u5e79\u7d30\u80de\u304c\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\u306e\u751f\u7269\u5b66\u306b\u3069\u306e\u3088\u3046\u306b\u5bfe\u51e6\u3059\u308b\u304b<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-who-is-and-is-not-a-good-candidate-for-mci-stem-cell-therapy-70\">\u8ab0\u304cMCI\u5e79\u7d30\u80de\u6cbb\u7642\u306e\u9069\u5207\u306a\u5019\u88dc\u8005\u3067\u3042\u308a\u3001\u8ab0\u304c\u305d\u3046\u3067\u306a\u3044\u304b<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-one-patients-experience-with-mci-stem-cell-therapy-in-malaysia-86\">\u30de\u30ec\u30fc\u30b7\u30a2\u3067\u306eMCI\u5e79\u7d30\u80de\u6cbb\u7642\u306b\u95a2\u3059\u308b\u3042\u308b\u60a3\u8005\u306e\u4f53\u9a13<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-honest-risks-and-limitations-of-stem-cell-therapy-for-mild-cognitive-impairment-113\">\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\u306b\u5bfe\u3059\u308b\u5e79\u7d30\u80de\u6cbb\u7642\u306e\u7387\u76f4\u306a\u30ea\u30b9\u30af\u3068\u9650\u754c<\/a><ol><\/ol><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-faq-about-mild-cognitive-impairment-stem-cell-therapy-52\">\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\u306b\u5bfe\u3059\u308b\u5e79\u7d30\u80de\u7642\u6cd5\u306b\u95a2\u3059\u308b\u3088\u304f\u3042\u308b\u8cea\u554f<\/a><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-next-steps-79\">\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\u304c\u3042\u308b\u5834\u5408\u306e\u6b21\u306e\u30b9\u30c6\u30c3\u30d7<\/a><\/li><li><a class=\"aioseo-toc-item\" href=\"#aioseo-references-160\">\u53c2\u8003\u6587\u732e<\/a><\/li><\/ol><\/div>\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-the-daily-reality-and-why-mild-cognitive-impairment-escapes-natural-repair-5\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\u306e\u9032\u884c\u4e2d\u3001\u8133\u306e\u5185\u90e8\u3067\u4f55\u304c\u8d77\u304d\u3066\u3044\u308b\u306e\u304b<\/mark><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-the-biology-of-memory-loss-in-mci-14\">MCI\u306b\u304a\u3051\u308b\u8a18\u61b6\u55aa\u5931\u306e\u751f\u7269\u5b66<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u8133\u306b\u306f\u7d04860\u5104\u500b\u306e\u30cb\u30e5\u30fc\u30ed\u30f3\uff08\u795e\u7d4c\u7d30\u80de\uff09\u304c\u3042\u308a\u3001\u81a8\u5927\u306a\u96fb\u6c17\u5316\u5b66\u4fe1\u53f7\u306e\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u3092\u901a\u3058\u3066\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3\u3092\u53d6\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u30cb\u30e5\u30fc\u30ed\u30f3\u306f\u30b7\u30ca\u30d7\u30b9\u3068\u547c\u3070\u308c\u308b\u63a5\u5408\u90e8\u3067\u3064\u306a\u304c\u3063\u3066\u304a\u308a\u30011\u3064\u306e\u7d30\u80de\u304c\u5316\u5b66\u4f1d\u9054\u7269\u8cea\uff08\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\uff09\u3092\u653e\u51fa\u3057\u3066\u5fae\u5c0f\u306a\u9699\u9593\u3092\u8d8a\u3048\u3001\u6b21\u306e\u7d30\u80de\u3092\u6d3b\u6027\u5316\u3057\u307e\u3059\u3002\u3053\u306e\u3088\u3046\u306b\u3057\u3066\u8a18\u61b6\u304c\u5f62\u6210\u3055\u308c\u3001\u4fdd\u5b58\u3055\u308c\u3001\u691c\u7d22\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\u3067\u306f\u3001\u3053\u306e\u30d7\u30ed\u30bb\u30b9\u304c\u7279\u5b9a\u306e\u9818\u57df\u3067\u6a5f\u80fd\u3057\u306a\u304f\u306a\u308a\u59cb\u3081\u307e\u3059\u3002\u65b0\u3057\u3044\u8a18\u61b6\u3092\u5f62\u6210\u3059\u308b\u305f\u3081\u306e\u8133\u306e\u4e3b\u8981\u306a\u69cb\u9020\u3067\u3042\u308b\u6d77\u99ac\u304c\u3001\u901a\u5e38\u6700\u521d\u306b\u5f71\u97ff\u3092\u53d7\u3051\u308b\u9818\u57df\u3067\u3059\u3002\u6d77\u99ac\u304a\u3088\u3073\u305d\u306e\u5468\u8fba\u306e\u30cb\u30e5\u30fc\u30ed\u30f3\u306f\u3001\u5b8c\u5168\u306a\u8a8d\u77e5\u75c7\u3092\u767a\u75c7\u3059\u308b\u305a\u3063\u3068\u524d\u304b\u3089\u3001\u63a5\u7d9a\u3092\u5931\u3044\u3001\u53ce\u7e2e\u3057\u3001\u5834\u5408\u306b\u3088\u3063\u3066\u306f\u6b7b\u6ec5\u3057\u59cb\u3081\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u5d29\u58ca\u306e\u6838\u5fc3\u306b\u306f2\u3064\u306e\u30d7\u30ed\u30bb\u30b9\u304c\u3042\u308a\u3001\u3069\u3061\u3089\u3082\u5e79\u7d30\u80de\u6cbb\u7642\u304c\u6a5f\u80fd\u3059\u308b\u3088\u3046\u306b\u8a2d\u8a08\u3055\u308c\u3066\u3044\u308b\u30e1\u30ab\u30cb\u30ba\u30e0\u3068\u751f\u7269\u5b66\u7684\u306b\u95a2\u9023\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">1\u3064\u76ee\u306f\u3001\u8133\u306e\u5185\u90e8\u306e\u6162\u6027\u7684\u306a\u708e\u75c7\u3067\u3042\u308b\u795e\u7d4c\u708e\u75c7\uff08Neuroinflammation\uff09\u3067\u3059\u3002\u8133\u306b\u306f\u30df\u30af\u30ed\u30b0\u30ea\u30a2\uff08Microglia\uff09\u3068\u547c\u3070\u308c\u308b\u72ec\u81ea\u306e\u514d\u75ab\u7d30\u80de\u304c\u3042\u308a\u3001\u901a\u5e38\u306e\u5f79\u5272\u306f\u30cb\u30e5\u30fc\u30ed\u30f3\u3092\u611f\u67d3\u304b\u3089\u4fdd\u8b77\u3057\u3001\u7d30\u80de\u306e\u6b8b\u9ab8\u3092\u53d6\u308a\u9664\u304f\u3053\u3068\u3067\u3059\u3002MCI\u3067\u306f\u3001\u3053\u308c\u3089\u306e\u30df\u30af\u30ed\u30b0\u30ea\u30a2\u304c\u4fdd\u8b77\u7684\u306a\u5f79\u5272\u304b\u3089\u7834\u58ca\u7684\u306a\u5f79\u5272\u3078\u3068\u79fb\u884c\u3057\u3001\u672c\u6765\u4fdd\u8b77\u3059\u3079\u304d\u30cb\u30e5\u30fc\u30ed\u30f3\u3092\u640d\u50b7\u3059\u308b\u708e\u75c7\u6027\u5206\u5b50\u3092\u653e\u51fa\u3057\u307e\u3059\u3002\u3053\u308c\u306f\u77ed\u671f\u9593\u306e\u514d\u75ab\u53cd\u5fdc\u3067\u306f\u306a\u304f\u3001\u8a8d\u77e5\u6a5f\u80fd\u306e\u4f4e\u4e0b\u3092\u4fc3\u9032\u3059\u308b\u3001\u6301\u7d9a\u7684\u3067\u4f4e\u30ec\u30d9\u30eb\u306e\u706b\u707d\u306e\u3088\u3046\u306a\u3082\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2\u3064\u76ee\u306f\u3001\u795e\u7d4c\u6804\u990a\u30b5\u30dd\u30fc\u30c8\u306e\u55aa\u5931\u3067\u3059\u3002\u30cb\u30e5\u30fc\u30ed\u30f3\u306f\u3001\u795e\u7d4c\u6804\u990a\u56e0\u5b50\u3068\u547c\u3070\u308c\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u50cd\u304d\u306b\u3088\u3063\u3066\u3042\u308b\u7a0b\u5ea6\u5065\u5eb7\u3092\u7dad\u6301\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u4e2d\u3067\u6700\u3082\u91cd\u8981\u306a\u306e\u304c\u8133\u7531\u6765\u795e\u7d4c\u6804\u990a\u56e0\u5b50\uff08Brain-Derived Neurotrophic Factor, BDNF\uff09\u3067\u3042\u308a\u3001\u8133\u7d30\u80de\u306e\u300c\u80a5\u6599\u300d\u3068\u8003\u3048\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002BDNF\u306f\u30cb\u30e5\u30fc\u30ed\u30f3\u306e\u751f\u5b58\u3092\u30b5\u30dd\u30fc\u30c8\u3057\u3001\u30b7\u30ca\u30d7\u30b9\u63a5\u7d9a\u306e\u7dad\u6301\u3092\u4fc3\u3057\u3001\u8a18\u61b6\u304c\u4f9d\u5b58\u3059\u308b\u8a8d\u77e5\u306e\u67d4\u8edf\u6027\u3092\u4fdd\u8b77\u3057\u307e\u3059\u3002MCI\u3067\u306f\u3001\u6d77\u99ac\u3068\u305d\u306e\u5468\u8fba\u9818\u57df\u306eBDNF\u30ec\u30d9\u30eb\u304c\u3001\u540c\u3058\u5e74\u9f62\u306e\u8a8d\u77e5\u6a5f\u80fd\u304c\u6b63\u5e38\u306a\u6210\u4eba\u3068\u6bd4\u8f03\u3057\u3066\u4e00\u8cab\u3057\u3066\u4f4e\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u795e\u7d4c\u708e\u75c7\u3068\u795e\u7d4c\u6804\u990a\u5265\u596a\u3068\u3044\u3046\u3053\u308c\u30892\u3064\u306e\u30d7\u30ed\u30bb\u30b9\u3053\u305d\u304c\u3001MSCs\u6cbb\u7642\u304c\u5bfe\u51e6\u3059\u308b\u3088\u3046\u306b\u8a2d\u8a08\u3055\u308c\u305f\u307e\u3055\u306b\u6a19\u7684\u306a\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-why-the-mci-brain-cannot-repair-itself-21\">\u306a\u305cMCI\u306e\u8133\u306f\u81ea\u3089\u3092\u4fee\u5fa9\u3067\u304d\u306a\u3044\u306e\u304b<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u640d\u50b7\u5f8c\u306b\u304b\u306a\u308a\u306e\u90e8\u5206\u3092\u518d\u751f\u3067\u304d\u308b\u809d\u81d3\u3084\u3001\u76ee\u306b\u898b\u3048\u308b\u50b7\u3092\u6570\u65e5\u3067\u6cbb\u7652\u3059\u308b\u76ae\u819a\u3068\u306f\u7570\u306a\u308a\u3001\u6210\u4eba\u306e\u8133\u306b\u306f\u5931\u308f\u308c\u305f\u30cb\u30e5\u30fc\u30ed\u30f3\u3092\u7f6e\u304d\u63db\u3048\u308b\u80fd\u529b\u304c\u307b\u3068\u3093\u3069\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u304cMCI\u306e\u4e2d\u5fc3\u7684\u306a\u751f\u7269\u5b66\u7684\u73fe\u5b9f\u3067\u3059\u3002\u6b7b\u6ec5\u3057\u305f\u30cb\u30e5\u30fc\u30ed\u30f3\u306f\u623b\u3063\u3066\u304d\u307e\u305b\u3093\u3002\u5207\u65ad\u3055\u308c\u305f\u63a5\u7d9a\u304c\u81ea\u7136\u306b\u518d\u5f62\u6210\u3055\u308c\u308b\u3053\u3068\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9069\u5207\u306a\u751f\u7269\u5b66\u7684\u30b5\u30dd\u30fc\u30c8\u304c\u3042\u308c\u3070\u8133\u304c\u3067\u304d\u308b\u3053\u3068\u306f\u3001\u6b8b\u3063\u3066\u3044\u308b\u30cb\u30e5\u30fc\u30ed\u30f3\u3092\u4fdd\u8b77\u3057\u3001\u307e\u3060\u640d\u306a\u308f\u308c\u3066\u3044\u306a\u3044\u63a5\u7d9a\u3092\u7dad\u6301\u3057\u3001\u3055\u3089\u306a\u308b\u640d\u50b7\u304c\u84c4\u7a4d\u3059\u308b\u901f\u5ea6\u3092\u9045\u3089\u305b\u308b\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u9650\u3089\u308c\u3066\u3044\u308b\u304c\u73fe\u5b9f\u7684\u306a\u67a0\u304c\u3042\u308b\u304b\u3089\u3053\u305d\u3001MCI\u306f\u3001\u3059\u3067\u306b\u9032\u884c\u3057\u305f\u672b\u671f\u8a8d\u77e5\u75c7\u3088\u308a\u3082\u5e79\u7d30\u80de\u6cbb\u7642\u306b\u3068\u3063\u3066\u6709\u671b\u306a\u6a19\u7684\u3068\u306a\u308b\u306e\u3067\u3059\u3002\u91cd\u5ea6\u306e\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u3067\u306f\u3001\u69cb\u9020\u7684\u640d\u50b7\u304c\u3042\u307e\u308a\u306b\u3082\u5e83\u7bc4\u3067\u3042\u308b\u305f\u3081\u3001\u4ecb\u5165\u306e\u305f\u3081\u306e\u751f\u7269\u5b66\u7684\u74b0\u5883\u304c\u8457\u3057\u304f\u5236\u9650\u3055\u308c\u307e\u3059\u3002MCI\u306b\u306f\u3001\u307e\u3060\u76f8\u5f53\u306a\u91cf\u306e\u751f\u5b58\u53ef\u80fd\u306a\u795e\u7d4c\u7d44\u7e54\u304c\u5b58\u5728\u3057\u307e\u3059\u3002\u81e8\u5e8a\u4e0a\u306e\u554f\u984c\u306f\u3001\u3053\u308c\u4ee5\u4e0a\u5931\u308f\u308c\u308b\u524d\u306b\u305d\u306e\u7d44\u7e54\u3092\u30b5\u30dd\u30fc\u30c8\u3057\u4fdd\u8b77\u3067\u304d\u308b\u304b\u3069\u3046\u304b\u3001\u305d\u3057\u3066\u305d\u3046\u3059\u308b\u3053\u3068\u3067\u3001\u305d\u306e\u8133\u306e\u6301\u3061\u4e3b\u306b\u3068\u3063\u3066\u610f\u5473\u306e\u3042\u308b\u9055\u3044\u304c\u751f\u307e\u308c\u308b\u304b\u3069\u3046\u304b\u3067\u3059\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-the-gap-in-standard-care-for-mild-cognitive-impairment-27\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\u306b\u304a\u3051\u308b\u6a19\u6e96\u6cbb\u7642\u306e\u30ae\u30e3\u30c3\u30d7<\/mark><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-what-conventional-treatment-for-mci-can-and-cannot-do-28\">MCI\u306e\u5f93\u6765\u306e\u6cbb\u7642\u304c\u3067\u304d\u308b\u3053\u3068\u3068\u3067\u304d\u306a\u3044\u3053\u3068<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u73fe\u5728\u3001\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\u306b\u5bfe\u3057\u3066\u627f\u8a8d\u3055\u308c\u305f\u85ac\u7269\u6cbb\u7642\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u3053\u308c\u306f\u533b\u5b66\u304c\u898b\u843d\u3068\u3057\u3066\u3044\u308b\u30ae\u30e3\u30c3\u30d7\u3067\u306f\u306a\u304f\u3001\u591a\u304f\u306e\u5927\u898f\u6a21\u306a\u81e8\u5e8a\u8a66\u9a13\u306e\u7d50\u679c\u3092\u53cd\u6620\u3057\u305f\u3082\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u795e\u7d4c\u4f1d\u9054\u7269\u8cea\u30a2\u30bb\u30c1\u30eb\u30b3\u30ea\u30f3\u306e\u5229\u7528\u53ef\u80fd\u6027\u3092\u9ad8\u3081\u308b\u30b3\u30ea\u30f3\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc\u963b\u5bb3\u85ac\uff08Cholinesterase inhibitors\uff09\u3067\u3042\u308b\u30c9\u30cd\u30da\u30b8\u30eb\uff08Donepezil\uff09\u3084\u30ea\u30d0\u30b9\u30c1\u30b0\u30df\u30f3\uff08Rivastigmine\uff09\u3001\u304a\u3088\u3073\u7570\u306a\u308b\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u7d4c\u8def\u3092\u8abf\u7bc0\u3059\u308b\u30e1\u30de\u30f3\u30c1\u30f3\uff08Memantine\uff09\u306a\u3069\u3001\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306b\u627f\u8a8d\u3055\u308c\u305f\u85ac\u5264\u306f\u3001MCI\u306e\u96c6\u56e3\u3067\u3082\u7814\u7a76\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u3069\u308c\u3082\u3001MCI\u306e\u6bb5\u968e\u306b\u3042\u308b\u4eba\u3005\u306b\u304a\u3044\u3066\u3001\u8a8d\u77e5\u75c7\u3078\u306e\u9032\u884c\u30ea\u30b9\u30af\u306e\u6709\u610f\u7fa9\u306a\u4f4e\u4e0b\u3084\u3001\u8a8d\u77e5\u30b9\u30b3\u30a2\u306e\u6301\u7d9a\u7684\u306a\u6539\u5584\u3092\u8a3c\u660e\u3057\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p 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style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-why-watching-and-waiting-feels-insufficient-for-many-mci-patients-34\">\u591a\u304f\u306eMCI\u60a3\u8005\u306b\u3068\u3063\u3066\u300c\u69d8\u5b50\u3092\u898b\u3066\u5f85\u3064\u300d\u3053\u3068\u304c\u4e0d\u5341\u5206\u306b\u611f\u3058\u3089\u308c\u308b\u7406\u7531<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u300c\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u3057\u3066\u3001\u307e\u305f1\u5e74\u5f8c\u306b\u6765\u3066\u304f\u3060\u3055\u3044\u300d\u3068\u3044\u3046\u30a2\u30c9\u30d0\u30a4\u30b9\u306f\u81e8\u5e8a\u7684\u306b\u306f\u6b63\u5f53\u3067\u3059\u304c\u3001\u3042\u308b\u7279\u5b9a\u306e\u610f\u5473\u3067\u611f\u60c5\u7684\u306b\u53d7\u3051\u5165\u308c\u304c\u305f\u3044\u3082\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u307b\u3068\u3093\u3069\u306e\u60a3\u8005\u306b\u3068\u3063\u3066\u3001MCI\u306b\u306f\u65b9\u5411\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u540c\u3058\u72b6\u614b\u306b\u3068\u3069\u307e\u308b\u3053\u3068\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u5909\u5316\u306e\u901f\u5ea6\u306f\u7570\u306a\u308a\u307e\u3059\u304c\uff08\u305d\u3057\u3066MCI\u306e\u5c11\u6570\u306e\u4eba\u306f5\u5e74\u4ee5\u5185\u306b\u8a8d\u77e5\u75c7\u306b\u9032\u884c\u3057\u307e\u305b\u3093\u304c\uff09\u3001\u9032\u884c\u3057\u3066\u3044\u308b\u4eba\u306b\u3068\u3063\u3066\u3001\u6bce\u5e74\u306e\u7d4c\u904e\u306f\u3001\u4e00\u5ea6\u5931\u308f\u308c\u308b\u3068\u56de\u5fa9\u3067\u304d\u306a\u3044\u73fe\u5b9f\u7684\u306a\u8a8d\u77e5\u306e\u55aa\u5931\u3092\u8868\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p 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class=\"wp-block-paragraph\">\u79c1\u305f\u3061\u306e\u30af\u30ea\u30cb\u30c3\u30af\u3092\u8a2a\u308c\u308b\u60a3\u8005\u306f\u3001\u751f\u6d3b\u7fd2\u6163\u306e\u7ba1\u7406\u3092\u3042\u304d\u3089\u3081\u305f\u4eba\u3005\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u5f7c\u3089\u306f\u901a\u5e38\u3001\u8a00\u308f\u308c\u305f\u3053\u3068\u3092\u3059\u3079\u3066\u5b9f\u884c\u3057\u305f\u306b\u3082\u304b\u304b\u308f\u3089\u305a\u3001\u81ea\u5206\u306e\u8a8d\u77e5\u6a5f\u80fd\u304c\u5909\u5316\u3057\u7d9a\u3051\u308b\u306e\u3092\u76ee\u306e\u5f53\u305f\u308a\u306b\u3057\u3066\u3044\u308b\u4eba\u3005\u3067\u3059\u3002\u5f7c\u3089\u306f\u3001\u533b\u5b66\u304c\u4f55\u304b\u4ed6\u306e\u3082\u306e\u3092\u63d0\u4f9b\u3067\u304d\u308b\u304b\u3069\u3046\u304b\u3092\u77e5\u308a\u305f\u304c\u3063\u3066\u3044\u307e\u3059\u3002\u5177\u4f53\u7684\u306b\u306f\u3001\u7d50\u679c\u3060\u3051\u3067\u306f\u306a\u304f\u3001\u6a5f\u80fd\u4f4e\u4e0b\u306e\u751f\u7269\u5b66\u7684\u30e1\u30ab\u30cb\u30ba\u30e0\u306b\u76f4\u63a5\u95a2\u4e0e\u3059\u308b\u4f55\u304b\u3092\u6c42\u3081\u3066\u3044\u308b\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-what-the-clinical-evidence-shows-for-stem-cell-therapy-in-mci-40\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u81e8\u5e8a\u7684\u8a3c\u62e0\u304cMCI\u306e\u5e79\u7d30\u80de\u6cbb\u7642\u306b\u3064\u3044\u3066\u793a\u3057\u3066\u3044\u308b\u3053\u3068<\/mark><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"965\" height=\"767\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/Cognitive-Function-Score-4.webp\" alt=\"\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\u60a3\u8005\u306b\u304a\u3051\u308b\u3001\u9593\u8449\u7cfb\u5e79\u7d30\u80de\u6cbb\u7642\u3092\u53d7\u3051\u305f\u7fa4\u3068\u30d7\u30e9\u30bb\u30dc\u7fa4\u306e\u8a8d\u77e5\u30b9\u30b3\u30a2\u4f4e\u4e0b\u7387\u309212\uff5e24\u30f6\u6708\u306b\u308f\u305f\u3063\u3066\u793a\u3057\u305f\u30b0\u30e9\u30d5\" class=\"wp-image-24611\" style=\"aspect-ratio:1.3239795918367347;width:662px;height:auto\" srcset=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/Cognitive-Function-Score-4.webp 965w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/Cognitive-Function-Score-4-300x238.webp 300w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/Cognitive-Function-Score-4-768x610.webp 768w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/Cognitive-Function-Score-4-893x710.webp 893w\" sizes=\"(max-width: 965px) 100vw, 965px\" \/><figcaption class=\"wp-element-caption\">\u767a\u8868\u3055\u308c\u305f\u7b2cI\/IIa\u76f8\u8a66\u9a13\u306b\u304a\u3044\u3066\u3001\u8efd\u5ea6\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u304a\u3088\u3073\u5065\u5fd8\u578bMCI\u306e\u96c6\u56e3\u306b\u304a\u3051\u308bMSCs\u6cbb\u7642\u306f\u3001\u30d7\u30e9\u30bb\u30dc\u7fa4\u3068\u6bd4\u8f03\u3057\u3066\u30df\u30cb\u30e1\u30f3\u30bf\u30eb\u30b9\u30c6\u30fc\u30c8\u691c\u67fb\uff08Mini-Mental State Examination, MMSE\uff09\u304a\u3088\u3073\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u8a55\u4fa1\u5c3a\u5ea6\u8a8d\u77e5\u30b5\u30d6\u30b9\u30b1\u30fc\u30eb\uff08Alzheimer&#8217;s Disease Assessment Scale Cognitive subscale, ADAS-Cog\uff09\u306e\u4f4e\u4e0b\u7387\u3092\u6e1b\u5c11\u3055\u305b\u307e\u3057\u305f\u3002\u3053\u306e\u52b9\u679c\u306f\u30016\u30f6\u6708\u6642\u70b9\u3088\u308a\u308212\u301c24\u30f6\u6708\u306e\u30d5\u30a9\u30ed\u30fc\u30a2\u30c3\u30d7\u3067\u3088\u308a\u660e\u78ba\u3067\u3057\u305f\u3002<\/figcaption><\/figure>\n<\/div>\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-key-clinical-studies-on-msc-therapy-for-mci-and-cognitive-decline-42\">MCI\u304a\u3088\u3073\u8a8d\u77e5\u6a5f\u80fd\u4f4e\u4e0b\u306b\u5bfe\u3059\u308bMSC\u6cbb\u7642\u306e\u4e3b\u8981\u306a\u81e8\u5e8a\u7814\u7a76<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u30c7\u30fc\u30bf\u3092\u898b\u308b\u524d\u306b\u91cd\u8981\u306a\u900f\u660e\u6027\u306e\u30dd\u30a4\u30f3\u30c8\u304c\u3042\u308a\u307e\u3059\u3002\u4eba\u9593\u306e\u88ab\u9a13\u8005\u3092\u5bfe\u8c61\u3068\u3057\u305fMSCs\u6cbb\u7642\u306b\u95a2\u3059\u308b\u6700\u3082\u53b3\u5bc6\u306a\u516c\u958b\u81e8\u5e8a\u7814\u7a76\u306f\u3001MCI\u306b\u7279\u5316\u3057\u305f\u3082\u306e\u3067\u306f\u306a\u304f\u3001\u4e3b\u306b\u8efd\u5ea6\u304b\u3089\u4e2d\u7b49\u5ea6\u306e\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u96c6\u56e3\u3092\u5bfe\u8c61\u306b\u5b9f\u65bd\u3055\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u3053\u306e\u3053\u3068\u306f\u306f\u3063\u304d\u308a\u3068\u8ff0\u3079\u308b\u4fa1\u5024\u304c\u3042\u308a\u307e\u3059\u3002\u8a18\u61b6\u306b\u7126\u70b9\u3092\u5f53\u3066\u305f\u30b5\u30d6\u30bf\u30a4\u30d7\u3067\u3042\u308b\u5065\u5fd8\u578bMCI\u306f\u3001\u73fe\u5728\u3001\u7814\u7a76\u8005\u306b\u3088\u3063\u3066\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u9023\u7d9a\u4f53\u306e\u6700\u3082\u521d\u671f\u306e\u81e8\u5e8a\u6bb5\u968e\u3092\u8868\u3059\u3082\u306e\u3068\u3057\u3066\u5e83\u304f\u7406\u89e3\u3055\u308c\u3066\u304a\u308a\u3001\u305d\u306e\u751f\u7269\u5b66\u306f\u5927\u5e45\u306b\u91cd\u8907\u3057\u3066\u3044\u307e\u3059\u3002\u3057\u304b\u3057\u3001\u96c6\u56e3\u306f\u540c\u4e00\u3067\u306f\u306a\u304f\u3001\u8a3c\u62e0\u306f\u3059\u3079\u3066\u306e\u30b1\u30fc\u30b9\u306b\u76f4\u63a5\u5f53\u3066\u306f\u307e\u308b\u3068\u3044\u3046\u3088\u308a\u306f\u3001\u63a8\u6e2c\u3055\u308c\u308b\u3082\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u80cc\u666f\u3092\u8e0f\u307e\u3048\u305f\u4e0a\u3067\u3001\u516c\u958b\u3055\u308c\u305f\u30c7\u30fc\u30bf\u304c\u793a\u3057\u3066\u3044\u308b\u5185\u5bb9\u3092\u8aac\u660e\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u65b9\u6cd5\u8ad6\u7684\u306b\u6700\u3082\u53b3\u683c\u306b\u5b8c\u4e86\u3057\u305f\u8a66\u9a13\u306e1\u3064\u306f\u30012021\u5e74\u306bAlzheimer&#8217;s Research and Therapy\u8a8c\u306b\u767a\u8868\u3055\u308c\u305f\u3001\u97d3\u56fd\u306eKwon\u3089\u306b\u3088\u3063\u3066\u5b9f\u65bd\u3055\u308c\u305f\u7b2cI\/IIa\u76f8\u7121\u4f5c\u70ba\u5316\u5bfe\u7167\u8a66\u9a13\u3067\u3042\u308bNEUROSTEM\u7814\u7a76\u3067\u3059\u3002\u3053\u306e\u8a66\u9a13\u3067\u306f\u300145\u4eba\u306e\u8efd\u5ea6\u304b\u3089\u4e2d\u7b49\u5ea6\u306e\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u60a3\u8005\u3092\u767b\u9332\u3057\u3001\u30d7\u30e9\u30bb\u30dc\u7fa4\u3068\u6bd4\u8f03\u3057\u30662\u3064\u306e\u7528\u91cf\u30ec\u30d9\u30eb\u3067\u81cd\u5e2f\u8840\u7531\u6765\u9593\u8449\u7cfb\u5e79\u7d30\u80de\u3092\u6295\u4e0e\u3057\u307e\u3057\u305f\u3002\u4e3b\u8981\u306a\u5b89\u5168\u6027\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u306f\u4e21\u65b9\u306e\u7528\u91cf\u30ec\u30d9\u30eb\u3067\u9054\u6210\u3055\u308c\u3001\u5e79\u7d30\u80de\u306b\u8d77\u56e0\u3059\u308b\u91cd\u7be4\u306a\u6709\u5bb3\u4e8b\u8c61\u306f\u3042\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u9ad8\u7528\u91cf\u7fa4\u3067\u306f\u3001\u81e8\u5e8a\u8a66\u9a13\u3067\u5e83\u304f\u4f7f\u7528\u3055\u308c\u3066\u3044\u308b\u8a18\u61b6\u3001\u8a00\u8a9e\u3001\u6ce8\u610f\u529b\u306e\u6a19\u6e96\u5316\u30c6\u30b9\u30c8\u3067\u3042\u308bADAS-Cog\u306e\u4f4e\u4e0b\u7387\u304c\u300124\u30f6\u6708\u306e\u6642\u70b9\u3067\u30d7\u30e9\u30bb\u30dc\u7fa4\u3088\u308a\u3082\u76ee\u306b\u898b\u3048\u3066\u9045\u304f\u306a\u308a\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u521d\u671f\u306eNEUROSTEM\u30b3\u30db\u30fc\u30c8\u3092\u4f7f\u7528\u3057\u305f\u3001Oh\u3089\uff082015\u5e74\uff09\u306b\u3088\u308bJournal of Alzheimer&#8217;s Disease\u8a8c\u306b\u767a\u8868\u3055\u308c\u305f\u7b2cI\u76f8\u8a66\u9a13\u3067\u306f\u30019\u4eba\u306e\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u60a3\u8005\u3092\u767b\u9332\u3057\u3001\u30d2\u30c8\u795e\u7d4c\u5e79\u7d30\u80de\u3092\u8133\u810a\u9ac4\u6db2\u8154\u306b\u76f4\u63a5\u7e70\u308a\u8fd4\u3057\u6ce8\u5165\u3057\u307e\u3057\u305f\u300224\u30f6\u6708\u9593\u306b\u308f\u305f\u308a\u30019\u4eba\u4e2d4\u4eba\u306e\u60a3\u8005\u304c\u3001\u672a\u6cbb\u7642\u306e\u96c6\u56e3\u3067\u4e88\u60f3\u3055\u308c\u308b\u4f4e\u4e0b\u7387\u3068\u6bd4\u8f03\u3057\u3066\u3001MMSE\uff0824\u70b9\u4ee5\u4e0a\u304c\u901a\u5e38\u306f\u6b63\u5e38\u306a\u8a8d\u77e5\u6a5f\u80fd\u3092\u793a\u305930\u70b9\u6e80\u70b9\u306e\u5c3a\u5ea6\uff09\u3067\u5b89\u5b9a\u5316\u307e\u305f\u306f\u4e2d\u7b49\u5ea6\u306e\u6539\u5584\u3092\u793a\u3057\u307e\u3057\u305f\u3002\u6cbb\u7642\u306b\u95a2\u9023\u3059\u308b\u91cd\u7be4\u306a\u6709\u5bb3\u4e8b\u8c61\u306f\u8a18\u9332\u3055\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u30de\u30ec\u30fc\u30b7\u30a2\u3067\u4f7f\u7528\u3055\u308c\u3066\u3044\u308b\u3001\u8133\u3084\u810a\u9ac4\u3078\u306e\u76f4\u63a5\u6ce8\u5c04\u3092\u907f\u3051\u308b\u9759\u8108\u5185\u6295\u4e0e\u30eb\u30fc\u30c8\u306b\u3064\u3044\u3066\u306f\u30012023\u5e74\u306bFrontiers in Aging Neuroscience\u8a8c\u306b\u767a\u8868\u3055\u308c\u305f\u7814\u7a76\u3067\u3001\u8efd\u5ea6\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u307e\u305f\u306f\u5065\u5fd8\u578bMCI\u306e\u60a3\u800540\u4eba\u3092\u767b\u9332\u3057\u3001\u81cd\u5e2f\u7531\u6765MSCs\u306e\u9759\u8108\u5185\u6ce8\u5165\u3068\u30d7\u30e9\u30bb\u30dc\u3092\u6bd4\u8f03\u3057\u307e\u3057\u305f\u300212\u30f6\u6708\u306e\u6642\u70b9\u3067\u3001\u6cbb\u7642\u7fa4\u306fMMSE\u4f4e\u4e0b\u7387\u306e\u7d71\u8a08\u7684\u306b\u6709\u610f\u306a\u6e1b\u5c11\u3092\u793a\u3057\u3001\u540c\u6642\u306b\u795e\u7d4c\u5909\u6027\u3067\u4e00\u8cab\u3057\u3066\u4e0a\u6607\u3059\u308b\u708e\u75c7\u4fc3\u9032\u6027\u5316\u5b66\u4f1d\u9054\u7269\u8cea\u3067\u3042\u308b\u8133\u810a\u9ac4\u6db2\u4e2d\u306e\u30a4\u30f3\u30bf\u30fc\u30ed\u30a4\u30ad\u30f3-6\uff08Interleukin-6\uff09\u30ec\u30d9\u30eb\u306e\u6e1b\u5c11\u3092\u793a\u3057\u307e\u3057\u305f\u3002\u3053\u306e\u52b9\u679c\u306f\u8efd\u5ea6\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u30b5\u30d6\u30b0\u30eb\u30fc\u30d7\u3088\u308a\u3082MCI\u306e\u30b5\u30d6\u30b0\u30eb\u30fc\u30d7\u3067\u9855\u8457\u3067\u3042\u308a\u3001\u3053\u308c\u306f\u751f\u7269\u5b66\u304c\u4e88\u6e2c\u3059\u308b\u3082\u306e\u3068\u4e00\u81f4\u3059\u308b\u767a\u898b\u3067\u3059\u3002\u3064\u307e\u308a\u3001\u795e\u7d4c\u74b0\u5883\u306e\u640d\u50b7\u304c\u5c11\u306a\u3044\u6bb5\u968e\u3067\u306e\u3088\u308a\u65e9\u671f\u306e\u4ecb\u5165\u304c\u3001\u3088\u308a\u660e\u78ba\u306a\u5229\u76ca\u3092\u751f\u307f\u51fa\u3059\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-what-realistic-improvement-looks-like-for-mci-patients-after-stem-cell-therapy-48\">\u5e79\u7d30\u80de\u6cbb\u7642\u5f8c\u3001MCI\u60a3\u8005\u306b\u3068\u3063\u3066\u73fe\u5b9f\u7684\u306a\u6539\u5584\u306f\u3069\u306e\u3088\u3046\u306a\u3082\u306e\u304b<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u79c1\u305f\u3061\u306f\u3001\u3053\u308c\u3089\u306e\u7d50\u679c\u304c\u5b9f\u969b\u7684\u306a\u7528\u8a9e\u3067\u4f55\u3092\u610f\u5473\u3059\u308b\u304b\u306b\u3064\u3044\u3066\u6b63\u78ba\u3067\u3042\u308a\u305f\u3044\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002\u306a\u305c\u306a\u3089\u3001\u6700\u826f\u306e\u7d50\u679c\u3092\u9078\u629e\u7684\u306b\u5831\u544a\u3059\u308b\u3053\u3068\u306f\u3001\u60a3\u8005\u306b\u4e0d\u5229\u76ca\u3092\u3082\u305f\u3089\u3059\u304b\u3089\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">MMSE\u30b9\u30b3\u30a2\u306f\u901a\u5e38\u3001\u6cbb\u7642\u3092\u53d7\u3051\u3066\u3044\u306a\u3044\u5065\u5fd8\u578bMCI\u304a\u3088\u3073\u521d\u671f\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u96c6\u56e3\u3067\u6bce\u5e74\u7d042\u301c4\u30dd\u30a4\u30f3\u30c8\u4f4e\u4e0b\u3057\u307e\u3059\u3002\u6700\u3082\u95a2\u9023\u6027\u306e\u9ad8\u3044\u516c\u958b\u8a66\u9a13\u306e\u6cbb\u7642\u7fa4\u3067\u306f\u3001\u305d\u306e\u4f4e\u4e0b\u7387\u304c\u6e1b\u5c11\u3057\u3001\u3044\u304f\u3064\u304b\u306e\u7814\u7a76\u3067\u306f\u5e74\u95931\u30dd\u30a4\u30f3\u30c8\u672a\u6e80\u306b\u306a\u308a\u3001\u4ed6\u306e\u7814\u7a76\u3067\u306f12\u301c24\u30f6\u6708\u306b\u308f\u305f\u3063\u3066\u307b\u307c\u5b89\u5b9a\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u308c\u306f\u300c\u9006\u8ee2\u300d\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u300c\u9045\u5ef6\u300d\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u591a\u304f\u306e\u60a3\u8005\u306b\u3068\u3063\u3066\u3001\u3053\u306e\u300c\u9045\u5ef6\u300d\u3053\u305d\u304c\u91cd\u8981\u306a\u306e\u3067\u3059\u3002\u6bce\u65e5\u306e\u5bb6\u8a08\u3092\u7ba1\u7406\u3057\u3001\u8907\u96d1\u306a\u4f1a\u8a71\u306b\u3064\u3044\u3066\u3044\u304d\u3001\u5c02\u9580\u7684\u306b\u8ca2\u732e\u3057\u7d9a\u3051\u3001\u81ea\u5b85\u3067\u306e\u81ea\u7acb\u3092\u7dad\u6301\u3059\u308b\u305f\u3081\u306e\u8a8d\u77e5\u80fd\u529b\u3092\u4fdd\u3064\u3053\u3068\u3067\u3059\u3002\u5e74\u95933\u30dd\u30a4\u30f3\u30c8\u306e\u4f4e\u4e0b\u3068\u5e74\u95930.5\u30dd\u30a4\u30f3\u30c8\u306e\u4f4e\u4e0b\u306e\u9055\u3044\u306f\u30015\u5e74\u9593\u3067\u6e2c\u5b9a\u3057\u305f\u5834\u5408\u3001\u6a5f\u80fd\u3057\u3066\u3044\u308b\u65e5\u5e38\u751f\u6d3b\u3068\u8457\u3057\u304f\u640d\u306a\u308f\u308c\u305f\u65e5\u5e38\u751f\u6d3b\u306e\u9055\u3044\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">MCI\u306b\u5bfe\u3059\u308b\u5e79\u7d30\u80de\u6cbb\u7642\u304c\u67fb\u8aad\u4ed8\u304d\u306e\u8a66\u9a13\u3067\u8a3c\u660e\u3057\u3066\u3044\u306a\u3044\u306e\u306f\u3001\u6cbb\u7642\u524d\u306b\u5931\u308f\u308c\u305f\u8a18\u61b6\u304c\u623b\u308b\u3053\u3068\u3067\u3059\u3002\u3059\u3067\u306b\u5fd8\u308c\u3066\u3057\u307e\u3063\u305f\u3053\u3068\u3092\u601d\u3044\u51fa\u3059\u3053\u3068\u3092\u671f\u5f85\u3057\u3066\u3053\u306e\u30d7\u30ed\u30bb\u30b9\u306b\u5165\u308b\u60a3\u8005\u306f\u3001\u975e\u73fe\u5b9f\u7684\u306a\u67a0\u7d44\u307f\u3067\u53d6\u308a\u7d44\u3093\u3067\u3044\u307e\u3059\u3002\u307e\u3060\u6301\u3063\u3066\u3044\u308b\u3082\u306e\u3092\u3088\u308a\u591a\u304f\u4fdd\u6301\u3057\u3001\u305d\u308c\u3092\u5931\u3044\u7d9a\u3051\u308b\u901f\u5ea6\u3092\u9045\u3089\u305b\u308b\u3053\u3068\u3092\u671f\u5f85\u3057\u3066\u5165\u308b\u60a3\u8005\u306f\u3001\u5229\u7528\u53ef\u80fd\u306a\u8a3c\u62e0\u304c\u88cf\u4ed8\u3051\u308b\u67a0\u7d44\u307f\u3067\u53d6\u308a\u7d44\u3093\u3067\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u79c1\u305f\u3061\u306e\u30d7\u30ed\u30b0\u30e9\u30e0\u3067\u6cbb\u7642\u3092\u53d7\u3051\u305fMCI\u60a3\u8005\u306e\u4e00\u5b9a\u306e\u5272\u5408\u306f\u3001\u6e2c\u5b9a\u53ef\u80fd\u306a\u5909\u5316\u3092\u793a\u3057\u307e\u305b\u3093\u3002\u5229\u7528\u53ef\u80fd\u306a\u8a66\u9a13\u30c7\u30fc\u30bf\u30687\u5e74\u9593\u306e\u79c1\u305f\u3061\u306e\u81e8\u5e8a\u7d4c\u9a13\u306b\u57fa\u3065\u304d\u3001MSCs\u6cbb\u7642\u3092\u53d7\u3051\u308bMCI\u60a3\u8005\u306e\u7d0430\u301c40\uff05\u304c\u300112\u301c24\u30f6\u6708\u306e\u671f\u9593\u306b\u308f\u305f\u3063\u3066\u3042\u308b\u7a0b\u5ea6\u306e\u6e2c\u5b9a\u53ef\u80fd\u306a\u5b89\u5b9a\u5316\u307e\u305f\u306f\u4f4e\u4e0b\u306e\u9045\u5ef6\u3092\u793a\u3059\u3068\u63a8\u5b9a\u3057\u3066\u3044\u307e\u3059\u3002\u6b8b\u308a\u306e60\u301c70\uff05\u306f\u3001\u9650\u5b9a\u7684\u306a\u52b9\u679c\u3057\u304b\u898b\u3089\u308c\u306a\u3044\u304b\u3001\u3042\u308b\u3044\u306f\u8a8d\u8b58\u3067\u304d\u308b\u52b9\u679c\u304c\u3042\u308a\u307e\u305b\u3093\u3002\u6cbb\u7642\u524d\u306b\u8ab0\u304c\u3069\u3061\u3089\u306e\u30b0\u30eb\u30fc\u30d7\u306b\u5165\u308b\u304b\u3092\u78ba\u5b9f\u306b\u4e88\u6e2c\u3059\u308b\u3053\u3068\u306f\u307e\u3060\u3067\u304d\u307e\u305b\u3093\u304c\uff08\u4ee5\u4e0b\u306e\u5019\u88dc\u57fa\u6e96\u306f\u6709\u610f\u7fa9\u306a\u30ac\u30a4\u30c0\u30f3\u30b9\u3092\u63d0\u4f9b\u3057\u307e\u3059\uff09\u3001\u3059\u3079\u3066\u306e\u76f8\u8ac7\u306b\u304a\u3044\u3066\u3053\u308c\u3092\u30aa\u30fc\u30d7\u30f3\u306b\u8b70\u8ad6\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-how-stem-cells-address-the-biology-of-mild-cognitive-impairment-56\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u5e79\u7d30\u80de\u304c\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\u306e\u751f\u7269\u5b66\u306b\u3069\u306e\u3088\u3046\u306b\u5bfe\u51e6\u3059\u308b\u304b<\/mark><\/h2>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full is-resized\"><img decoding=\"async\" width=\"972\" height=\"779\" src=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/1-Microglia-switching-from-inflammatory-to-protective-state-3.webp\" alt=\"\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\u306b\u5bfe\u3059\u308b\u9593\u8449\u7cfb\u5e79\u7d30\u80de\u7642\u6cd5\u306e3\u3064\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\uff08\u795e\u7d4c\u708e\u75c7\u306e\u8efd\u6e1b\u3001BDNF\u795e\u7d4c\u6804\u990a\u56e0\u5b50\u306e\u30b5\u30dd\u30fc\u30c8\u3001\u30b7\u30ca\u30d7\u30b9\u7d50\u5408\u306e\u4fdd\u8b77\uff09\u3092\u793a\u3059\u79d1\u5b66\u7684\u56f3\u3002\" class=\"wp-image-24612\" style=\"width:592px\" srcset=\"https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/1-Microglia-switching-from-inflammatory-to-protective-state-3.webp 972w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/1-Microglia-switching-from-inflammatory-to-protective-state-3-300x240.webp 300w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/1-Microglia-switching-from-inflammatory-to-protective-state-3-768x616.webp 768w, https:\/\/stemcell-malaysia.com\/wp-content\/uploads\/2026\/04\/1-Microglia-switching-from-inflammatory-to-protective-state-3-886x710.webp 886w\" sizes=\"(max-width: 972px) 100vw, 972px\" \/><figcaption class=\"wp-element-caption\">\u9593\u8449\u7cfb\u5e79\u7d30\u80de\u306f\u3001\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\u306b\u304a\u3044\u30663\u3064\u306e\u91cd\u8907\u3059\u308b\u751f\u7269\u5b66\u7684\u7d4c\u8def\u3092\u901a\u3058\u3066\u6a5f\u80fd\u3057\u307e\u3059\u3002\u3059\u306a\u308f\u3061\u3001\u904e\u5270\u306b\u6d3b\u52d5\u3057\u3066\u3044\u308b\u795e\u7d4c\u708e\u75c7\u3092\u93ae\u3081\u308b\u3053\u3068\u3001\u65e2\u5b58\u306e\u30cb\u30e5\u30fc\u30ed\u30f3\u306b\u5bfe\u3059\u308b\u795e\u7d4c\u6804\u990a\u30b5\u30dd\u30fc\u30c8\u3092\u56de\u5fa9\u3059\u308b\u3053\u3068\u3001\u305d\u3057\u3066\u8840\u6d41\u304c\u4e0d\u8db3\u3057\u3066\u3044\u308b\u8133\u7d44\u7e54\u3078\u306e\u8840\u7ba1\u4f9b\u7d66\u3092\u6539\u5584\u3059\u308b\u3053\u3068\u3067\u3059\u3002<\/figcaption><\/figure>\n<\/div>\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-three-biological-mechanisms-of-msc-therapy-in-mci-58\">MCI\u306b\u304a\u3051\u308bMSC\u6cbb\u7642\u306e3\u3064\u306e\u751f\u7269\u5b66\u7684\u30e1\u30ab\u30cb\u30ba\u30e0<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u72b6\u6cc1\u306b\u304a\u3044\u3066\u3001MSCs\u306f\u5931\u308f\u308c\u305f\u30cb\u30e5\u30fc\u30ed\u30f3\u3092\u300c\u7f6e\u304d\u63db\u3048\u308b\u300d\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u5e79\u7d30\u80de\u304c\u65b0\u3057\u3044\u30cb\u30e5\u30fc\u30ed\u30f3\u306b\u5909\u5316\u3059\u308b\u3053\u3068\u3067\u8133\u7d44\u7e54\u3092\u76f4\u63a5\u518d\u751f\u3067\u304d\u308b\u3068\u3044\u3046\u7406\u8ad6\u306f\u3001\u904e\u53bb20\u5e74\u9593\u306e\u7814\u7a76\u306b\u3088\u3063\u3066\u5f90\u3005\u306b\u89e3\u660e\u3055\u308c\u3066\u304d\u307e\u3057\u305f\u3002MSCs\u306f\u5b9f\u9a13\u5ba4\u306e\u6761\u4ef6\u4e0b\u3067\u306f\u3055\u307e\u3056\u307e\u306a\u7d30\u80de\u30bf\u30a4\u30d7\u306b\u5206\u5316\u3067\u304d\u307e\u3059\u304c\u3001\u640d\u50b7\u3057\u305f\u4eba\u9593\u306e\u8133\u306e\u751f\u4f53\u5185\u3067\u306f\u3001\u3053\u308c\u306f\u6709\u610f\u7fa9\u306b\u767a\u751f\u3057\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8a3c\u62e0\u304c\u88cf\u4ed8\u3051\u3066\u3044\u308b\u306e\u306f\u3001MCI\u3092\u9032\u884c\u3055\u305b\u308b\u30d7\u30ed\u30bb\u30b9\u305d\u306e\u3082\u306e\u306b\u5bfe\u51e6\u3059\u308b\u3001\u9593\u63a5\u7684\u3067\u306f\u3042\u308b\u3082\u306e\u306e\u751f\u7269\u5b66\u7684\u306b\u91cd\u8981\u306a\u4e00\u9023\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u3067\u3059\u3002<\/p>\n\n\n\n<p 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class=\"wp-block-paragraph\">2\u3064\u76ee\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u306f\u3001\u795e\u7d4c\u6804\u990a\u56e0\u5b50\u306e\u30b5\u30dd\u30fc\u30c8\u3067\u3059\u3002MSCs\u306fBDNF\uff08\u6709\u9178\u7d20\u904b\u52d5\u3067\u81ea\u7136\u306b\u5897\u52a0\u3059\u308b\u306e\u3068\u540c\u3058\u30bf\u30f3\u30d1\u30af\u8cea\uff09\u306b\u52a0\u3048\u3066\u3001\u795e\u7d4c\u6210\u9577\u56e0\u5b50\uff08Nerve Growth Factor, NGF\uff09\u3084\u8840\u7ba1\u5185\u76ae\u7d30\u80de\u5897\u6b96\u56e0\u5b50\uff08Vascular Endothelial Growth Factor, 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class=\"wp-block-paragraph\">\u6cbb\u7642\u76ee\u6a19\u304c\u7d30\u80de\u304c\u63d0\u4f9b\u3059\u308b\u795e\u7d4c\u6804\u990a\u304a\u3088\u3073\u6297\u708e\u75c7\u30b7\u30b0\u30ca\u30eb\u306e\u8cea\u3068\u52b9\u529b\u306b\u76f4\u63a5\u4f9d\u5b58\u3057\u3066\u3044\u308b\u72b6\u614b\u306b\u304a\u3044\u3066\u3001\u82e5\u3044\u30c9\u30ca\u30fc\u7d30\u80de\u3068\u9ad8\u9f62\u60a3\u8005\u81ea\u8eab\u306e\u8001\u5316\u7d30\u80de\u3068\u306e\u9593\u306e\u751f\u7269\u5b66\u7684\u9055\u3044\u306f\u5076\u7136\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u305d\u308c\u306f\u4ecb\u5165\u304c\u610f\u5473\u306e\u3042\u308b\u52b9\u679c\u306e\u95be\u5024\u306b\u5230\u9054\u3067\u304d\u308b\u304b\u3069\u3046\u304b\u306e\u4e2d\u5fc3\u7684\u306a\u8981\u7d20\u306a\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-who-is-and-is-not-a-good-candidate-for-mci-stem-cell-therapy-70\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u8ab0\u304cMCI\u5e79\u7d30\u80de\u6cbb\u7642\u306e\u9069\u5207\u306a\u5019\u88dc\u8005\u3067\u3042\u308a\u3001\u8ab0\u304c\u305d\u3046\u3067\u306a\u3044\u304b<\/mark><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-mci-profiles-that-tend-to-respond-better-to-msc-treatment-71\">MSC\u6cbb\u7642\u306b\u3088\u304f\u53cd\u5fdc\u3059\u308b\u50be\u5411\u304c\u3042\u308bMCI\u306e\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">MCI\u306e\u8a3a\u65ad\u3092\u53d7\u3051\u305f\u3059\u3079\u3066\u306e\u4eba\u304cMSCs\u6cbb\u7642\u306e\u9069\u5207\u306a\u5019\u88dc\u8005\u3068\u3044\u3046\u308f\u3051\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u79c1\u305f\u3061\u306f\u3053\u308c\u3092\u614e\u91cd\u306b\u8a55\u4fa1\u3057\u3001\u30a8\u30d3\u30c7\u30f3\u30b9\u304c\u7279\u5b9a\u306e\u72b6\u6cc1\u306b\u304a\u3044\u3066\u6cbb\u7642\u3092\u652f\u6301\u3057\u306a\u3044\u3068\u8003\u3048\u308b\u5834\u5408\u306f\u3001\u305d\u306e\u65e8\u3092\u660e\u78ba\u306b\u60a3\u8005\u306b\u4f1d\u3048\u308b\u3053\u3068\u3082\u8f9e\u3055\u306a\u3044\u59ff\u52e2\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u81e8\u5e8a\u30c7\u30fc\u30bf\u304a\u3088\u3073\u79c1\u305f\u3061\u81ea\u8eab\u306e\u60a3\u8005\u306e\u7d4c\u9a13\u306b\u304a\u3044\u3066\u3001\u6700\u3082\u4e00\u8cab\u3057\u305f\u5229\u76ca\u3092\u793a\u3057\u305f\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u306f\u3001\u3044\u304f\u3064\u304b\u306e\u7279\u5fb4\u3092\u5171\u6709\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8a3a\u65ad\u304c\u6700\u8fd1\u3067\u3042\u308a\u3001\u969c\u5bb3\u306e\u7a0b\u5ea6\u304c\u8efd\u5ea6\u304b\u3089\u4e2d\u7b49\u5ea6\u3067\u3042\u308b\u5834\u5408\uff1a\u8a8d\u77e5\u30c6\u30b9\u30c8\u3067\u3001\u610f\u5473\u306e\u3042\u308b\u8a8d\u77e5\u4e88\u5099\u80fd\u304c\u6b8b\u3063\u3066\u3044\u308b\u3053\u3068\u3092\u793a\u3059\u7bc4\u56f2\u306b\u3042\u308b\u60a3\u8005\uff08\u901a\u5e38\u300130\u70b9\u6e80\u70b9\u306eMMSE\u30b9\u30b3\u30a2\u304c24\u301c28\u3001\u307e\u305f\u306f\u30e2\u30f3\u30c8\u30ea\u30aa\u30fc\u30eb\u8a8d\u77e5\u8a55\u4fa1\uff08Montreal Cognitive Assessment, MoCA\uff09\u30b9\u30b3\u30a2\u304c19\u301c25\uff09\u3002\u4f4e\u4e0b\u306f\u9032\u884c\u6027\u3067\u3059\u304c\u3001\u65e5\u3005\u306e\u81ea\u7acb\u3057\u305f\u6a5f\u80fd\u304c\u8457\u3057\u304f\u640d\u306a\u308f\u308c\u308b\u6bb5\u968e\u306b\u306f\u307e\u3060\u9054\u3057\u3066\u3044\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8133MRI\u3067\u3001\u65e9\u671f\u306e\u795e\u7d4c\u5909\u6027\u5909\u5316\u3068\u4e00\u81f4\u3059\u308b\u6d77\u99ac\u306e\u840e\u7e2e\u304c\u898b\u3089\u308c\u308b\u304c\u3001\u4e2d\u7b49\u5ea6\u304b\u3089\u91cd\u5ea6\u306e\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306b\u7279\u5fb4\u7684\u306a\u5e83\u7bc4\u306a\u76ae\u8cea\u53ce\u7e2e\u306f\u306a\u3044\u5834\u5408\u3002\u8a00\u3044\u63db\u3048\u308c\u3070\u3001\u751f\u5b58\u53ef\u80fd\u306a\u795e\u7d4c\u69cb\u9020\u304c\u307e\u3060\u5341\u5206\u306b\u5b58\u5728\u3057\u3066\u3044\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u708e\u75c7\u30de\u30fc\u30ab\u30fc\uff08C\u53cd\u5fdc\u6027\u30bf\u30f3\u30d1\u30af\uff08C-reactive protein, 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class=\"wp-block-paragraph\">\u8840\u7ba1\u30ea\u30b9\u30af\u56e0\u5b50\uff08\u9ad8\u8840\u5727\u3001\u7cd6\u5c3f\u75c5\u3001\u307e\u305f\u306fMRI\u3067\u898b\u3048\u308b\u5fae\u5c0f\u8840\u7ba1\u75be\u60a3\uff09\u304c\u5b58\u5728\u3059\u308b\u304c\u3001\u7a4d\u6975\u7684\u306b\u7ba1\u7406\u3055\u308c\u3066\u3044\u308b\u5834\u5408\u3002\u3053\u308c\u3089\u306e\u60a3\u8005\u306b\u304a\u3044\u3066\u3001MSCs\u6cbb\u7642\u306e\u8840\u7ba1\u30b5\u30dd\u30fc\u30c8\u30e1\u30ab\u30cb\u30ba\u30e0\u306f\u795e\u7d4c\u708e\u75c7\u7d4c\u8def\u3092\u8d85\u3048\u308b\u5229\u76ca\u3092\u63d0\u4f9b\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u3001\u305d\u306e\u7279\u5b9a\u306e\u75be\u60a3\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u306b\u5bfe\u3059\u308b\u3088\u308a\u5305\u62ec\u7684\u306a\u751f\u7269\u5b66\u7684\u4ecb\u5165\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u60a3\u8005\u304c\u533b\u5b66\u7684\u306b\u5b89\u5b9a\u3057\u3066\u304a\u308a\u3001\u6d3b\u52d5\u6027\u306e\u60aa\u6027\u816b\u760d\u3001\u5168\u8eab\u611f\u67d3\u75c7\u3001\u307e\u305f\u306f\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3055\u308c\u3066\u3044\u306a\u3044\u4ee3\u8b1d\u75be\u60a3\u304c\u306a\u304f\u3001\u514d\u75ab\u6a5f\u80fd\u3092\u8457\u3057\u304f\u6291\u5236\u3059\u308b\u85ac\u5264\u3092\u670d\u7528\u3057\u3066\u3044\u306a\u3044\u3053\u3068\u3002<\/p>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"aioseo-when-stem-cell-therapy-is-not-the-right-path-for-mci-79\">\u5e79\u7d30\u80de\u6cbb\u7642\u304cMCI\u306b\u5bfe\u3059\u308b\u6b63\u3057\u3044\u9053\u3067\u306f\u306a\u3044\u5834\u5408<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u79c1\u305f\u3061\u306f\u3001\u6cbb\u7642\u3092\u9032\u3081\u306a\u3044\u3088\u3046\u660e\u78ba\u306b\u30a2\u30c9\u30d0\u30a4\u30b9\u3059\u308b\u81e8\u5e8a\u7684\u72b6\u6cc1\u304c\u3042\u308a\u307e\u3059\u3002\u3053\u306e\u660e\u78ba\u3055\u306f\u843d\u80c6\u3055\u305b\u308b\u305f\u3081\u306e\u3082\u306e\u3067\u306f\u306a\u304f\u3001\u8aa0\u5b9f\u306b\u884c\u308f\u308c\u308b\u6c7a\u5b9a\u306e\u57fa\u76e4\u3068\u306a\u308b\u3082\u306e\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">MCI\u3092\u8d85\u3048\u3066\u8efd\u5ea6\u8a8d\u77e5\u75c7\u306b\u9032\u884c\u3057\u305f\u60a3\u8005\uff08\u7279\u306bMMSE\u30b9\u30b3\u30a2\u304c20\u672a\u6e80\u306e\u60a3\u8005\uff09\u306f\u3001\u3088\u308a\u6df1\u523b\u306a\u640d\u50b7\u3092\u53d7\u3051\u305f\u795e\u7d4c\u57fa\u76e4\u3092\u6271\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u6bb5\u968e\u3067\u306fMSCs\u306e\u6709\u76ca\u6027\u306b\u95a2\u3059\u308b\u30a8\u30d3\u30c7\u30f3\u30b9\u306f\u5f31\u304f\u3001\u5229\u7528\u53ef\u80fd\u306a\u751f\u7269\u5b66\u7684\u74b0\u5883\u306f\u3055\u3089\u306b\u5236\u9650\u3055\u308c\u307e\u3059\u3002\u95a2\u7bc0\u30ea\u30a6\u30de\u30c1\uff08\u708e\u75c7\u304c\u6d3b\u767a\u3067\u3042\u3063\u3066\u3082\u95a2\u7bc0\u7834\u58ca\u304c\u672b\u671f\u306b\u9054\u3057\u3066\u3044\u306a\u3044\u5834\u5408\u306bMSCs\u6cbb\u7642\u304c\u6700\u3082\u52b9\u679c\u7684\u3067\u3042\u308b\uff09\u3068\u540c\u69d8\u306b\u3001\u8a8d\u77e5\u6a5f\u80fd\u4f4e\u4e0b\u306b\u5bfe\u3059\u308b\u5e79\u7d30\u80de\u6cbb\u7642\u306f\u3001\u5e83\u7bc4\u306a\u795e\u7d4c\u55aa\u5931\u304c\u3059\u3067\u306b\u8d77\u3053\u308b\u524d\u306b\u884c\u3046\u306e\u304c\u6700\u3082\u6709\u7528\u3067\u3042\u308b\u3068\u601d\u308f\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p 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class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h4 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-3-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" id=\"accordion-item-3\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span class=\"wp-block-accordion-heading__toggle-title\">\u6cbb\u7642\u524d\u307e\u305f\u306f\u6cbb\u7642\u4e2d\u306b\u3001\u73fe\u5728\u670d\u7528\u3057\u3066\u3044\u308b\u85ac\u3092\u4e2d\u6b62\u3059\u308b\u5fc5\u8981\u306f\u3042\u308a\u307e\u3059\u304b\uff1f<\/span><span class=\"wp-block-accordion-heading__toggle-icon\" aria-hidden=\"true\">+<\/span><\/button><\/h4>\n\n\n\n<div aria-labelledby=\"accordion-item-3\" data-wp-bind--hidden=\"state.isHidden\" data-wp-on--beforematch=\"actions.handleBeforeMatch\" id=\"accordion-item-3-panel\" role=\"region\" class=\"wp-block-accordion-panel is-layout-flow wp-block-accordion-panel-is-layout-flow\">\n<p class=\"wp-block-paragraph\">\u3044\u3044\u3048\u3002<br>MCI\uff08\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\uff09\u306e\u60a3\u8005\u69d8\u306b\u306f\u3001\u6cbb\u7642\u524d\u3001\u6cbb\u7642\u4e2d\u3001\u6cbb\u7642\u5f8c\u3092\u554f\u308f\u305a\u3001\u73fe\u5728\u670d\u7528\u4e2d\u306e\u85ac\u3092\u4e2d\u6b62\u3057\u3066\u3044\u305f\u3060\u304f\u3088\u3046\u304a\u9858\u3044\u3059\u308b\u3053\u3068\u306f\u3042\u308a\u307e\u305b\u3093\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u795e\u7d4c\u5185\u79d1\u533b\u307e\u305f\u306f\u304b\u304b\u308a\u3064\u3051\u533b\u304b\u3089\u51e6\u65b9\u3055\u308c\u305f\u85ac\u3092\u670d\u7528\u3055\u308c\u3066\u3044\u308b\u5834\u5408\u306f\u3001\u51e6\u65b9\u3069\u304a\u308a\u306b\u670d\u7528\u3092\u7d9a\u3051\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u85ac\u306e\u8abf\u6574\u306f\u3001\u5f53\u9662\u306e\u63a8\u5968\u306e\u307f\u306b\u57fa\u3065\u3044\u3066\u884c\u3046\u306e\u3067\u306f\u306a\u304f\u3001\u60a3\u8005\u69d8\u306e\u7dcf\u5408\u7684\u306a\u81e8\u5e8a\u50cf\u306b\u57fa\u3065\u304d\u3001\u62c5\u5f53\u533b\u3068\u76f8\u8ac7\u306e\u4e0a\u3067\u884c\u3063\u3066\u304f\u3060\u3055\u3044\u3002<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div data-wp-context=\"{ &quot;autoclose&quot;: false, &quot;accordionItems&quot;: [] }\" data-wp-interactive=\"core\/accordion\" role=\"group\" class=\"wp-block-accordion is-layout-flow wp-block-accordion-is-layout-flow\">\n<div data-wp-class--is-open=\"state.isOpen\" data-wp-context=\"{ &quot;id&quot;: &quot;accordion-item-4&quot;, &quot;openByDefault&quot;: false }\" data-wp-init=\"callbacks.initAccordionItems\" data-wp-on-window--hashchange=\"callbacks.hashChange\" class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h4 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-4-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" id=\"accordion-item-4\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span class=\"wp-block-accordion-heading__toggle-title\">MCI\uff08\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\uff09\u306e\u6cbb\u7642\u306b\u306f\u3001\u901a\u5e38\u4f55\u56de\u306e\u70b9\u6ef4\u6295\u4e0e\u304c\u63a8\u5968\u3055\u308c\u307e\u3059\u304b\uff1f<\/span><span class=\"wp-block-accordion-heading__toggle-icon\" aria-hidden=\"true\">+<\/span><\/button><\/h4>\n\n\n\n<div aria-labelledby=\"accordion-item-4\" data-wp-bind--hidden=\"state.isHidden\" data-wp-on--beforematch=\"actions.handleBeforeMatch\" id=\"accordion-item-4-panel\" role=\"region\" class=\"wp-block-accordion-panel is-layout-flow wp-block-accordion-panel-is-layout-flow\">\n<p 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class=\"wp-block-paragraph\">\u8ffd\u8de1\u8abf\u67fb\u3067\u5ba2\u89b3\u7684\u306a\u52b9\u679c\u306e\u8a3c\u62e0\u304c\u5f97\u3089\u308c\u306a\u3044\u9650\u308a\u3001\u7121\u671f\u9650\u306e\u70b9\u6ef4\u30b9\u30b1\u30b8\u30e5\u30fc\u30eb\u306f\u63d0\u4f9b\u3057\u3066\u304a\u308a\u307e\u305b\u3093\u3002<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div data-wp-context=\"{ &quot;autoclose&quot;: false, &quot;accordionItems&quot;: [] }\" data-wp-interactive=\"core\/accordion\" role=\"group\" class=\"wp-block-accordion is-layout-flow wp-block-accordion-is-layout-flow\">\n<div data-wp-class--is-open=\"state.isOpen\" data-wp-context=\"{ &quot;id&quot;: &quot;accordion-item-5&quot;, &quot;openByDefault&quot;: false }\" data-wp-init=\"callbacks.initAccordionItems\" data-wp-on-window--hashchange=\"callbacks.hashChange\" class=\"wp-block-accordion-item is-layout-flow wp-block-accordion-item-is-layout-flow\">\n<h4 class=\"wp-block-accordion-heading\"><button aria-expanded=\"false\" aria-controls=\"accordion-item-5-panel\" data-wp-bind--aria-expanded=\"state.isOpen\" data-wp-on--click=\"actions.toggle\" id=\"accordion-item-5\" type=\"button\" class=\"wp-block-accordion-heading__toggle\"><span class=\"wp-block-accordion-heading__toggle-title\">\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\uff08MCI\uff09\u306b\u5bfe\u3059\u308b\u5e79\u7d30\u80de\u6cbb\u7642\u306f\u3001\u5065\u5eb7\u4fdd\u967a\u306e\u5bfe\u8c61\u3068\u306a\u308a\u307e\u3059\u304b\uff1f<\/span><span class=\"wp-block-accordion-heading__toggle-icon\" aria-hidden=\"true\">+<\/span><\/button><\/h4>\n\n\n\n<div aria-labelledby=\"accordion-item-5\" data-wp-bind--hidden=\"state.isHidden\" data-wp-on--beforematch=\"actions.handleBeforeMatch\" id=\"accordion-item-5-panel\" role=\"region\" class=\"wp-block-accordion-panel is-layout-flow wp-block-accordion-panel-is-layout-flow\">\n<p class=\"wp-block-paragraph\">\u3044\u3044\u3048\u3002\u8efd\u5ea6\u8a8d\u77e5\u969c\u5bb3\u306b\u5bfe\u3059\u308b\u5e79\u7d30\u80de\u6cbb\u7642\u306f\u3001\u30de\u30ec\u30fc\u30b7\u30a2\u3001\u65e5\u672c\u3001\u305d\u306e\u4ed6\u307b\u3068\u3093\u3069\u306e\u56fd\u306b\u304a\u3044\u3066\u3001\u901a\u5e38\u306e\u5065\u5eb7\u4fdd\u967a\u306e\u9069\u7528\u5bfe\u8c61\u5916\u3068\u306a\u308b\u3001\u81ea\u5df1\u8ca0\u62c5\u306e\u79c1\u7684\u533b\u7642\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u8a18\u4e8b\u3067\u306f\u5177\u4f53\u7684\u306a\u8cbb\u7528\u306b\u3064\u3044\u3066\u306f\u89e6\u308c\u307e\u305b\u3093\u304c\u3001\u521d\u56de\u30aa\u30f3\u30e9\u30a4\u30f3\u76f8\u8ac7\u6642\u306b\u8a73\u7d30\u306a\u60c5\u5831\u3092\u63d0\u4f9b\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n<\/div>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-next-steps-79\"><mark 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class=\"wp-block-paragraph\">\u79c1\u305f\u3061\u306f\u3001\u307e\u3055\u306b\u305d\u306e\u3088\u3046\u306a\u3054\u76f8\u8ac7\u306e\u305f\u3081\u306b\u3001\u7121\u6599\u306e\u30aa\u30f3\u30e9\u30a4\u30f3\u76f8\u8ac7\u3092\u63d0\u4f9b\u3057\u3066\u3044\u307e\u3059\u3002\u795e\u7d4c\u5fc3\u7406\u5b66\u7684\u691c\u67fb\u7d50\u679c\u3001MRI\u30ec\u30dd\u30fc\u30c8\u3001\u6700\u8fd1\u306e\u8840\u6db2\u691c\u67fb\u7d50\u679c\u3001\u305d\u3057\u3066\u3054\u8cea\u554f\u3092\u3054\u7528\u610f\u304f\u3060\u3055\u3044\u3002\u3042\u306a\u305f\u306e\u81e8\u5e8a\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u304c\u3001MSC\u7642\u6cd5\u306b\u3088\u308b\u6f5c\u5728\u7684\u306a\u52b9\u679c\u304c\u8a8d\u3081\u3089\u308c\u308b\u7bc4\u56f2\u306b\u8a72\u5f53\u3059\u308b\u304b\u3069\u3046\u304b\u3001\u307e\u305f\u8a72\u5f53\u3057\u306a\u3044\u5834\u5408\u3082\u540c\u69d8\u306b\u6b63\u76f4\u306b\u304a\u4f1d\u3048\u3057\u307e\u3059\u3002\u6cbb\u7642\u3092\u53d7\u3051\u308b\u7fa9\u52d9\u306f\u4e00\u5207\u306a\u304f\u3001\u76f8\u8ac7\u306f\u3042\u304f\u307e\u3067\u81e8\u5e8a\u7684\u306a\u8a71\u3057\u5408\u3044\u3067\u3042\u308a\u3001\u55b6\u696d\u6d3b\u52d5\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u591a\u304f\u306e\u65b9\u304c\u3001\u3054\u81ea\u8eab\u306e\u72b6\u6cc1\u306b\u304a\u3051\u308b\u30a8\u30d3\u30c7\u30f3\u30b9\u3092\u7406\u89e3\u3059\u308b\u305f\u3081\u306b\u3053\u306e\u76f8\u8ac7\u3092\u5229\u7528\u3057\u3001\u3088\u308a\u591a\u304f\u306e\u60c5\u5831\u3092\u5f97\u305f\u4e0a\u3067\u3001\u4f55\u3082\u6c7a\u65ad\u3059\u308b\u3053\u3068\u306a\u304f\u304a\u5e30\u308a\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 class=\"wp-block-heading\" id=\"aioseo-references-160\"><mark style=\"background-color:#dce9f5\" class=\"has-inline-color\">\u53c2\u8003\u6587\u732e<\/mark><\/h2>\n\n\n\n<ol class=\"wp-block-list\">\n<li>GBD 2019 Dementia Forecasting Collaborators. &#8220;Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050: an analysis for the Global Burden of Disease Study 2019.&#8221; <em>The Lancet Public Health<\/em>, 7(2):e105\u2013e125, 2022. <a href=\"https:\/\/doi.org\/10.1016\/S2468-2667(21)00249-8\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1016\/S2468-2667(21)00249-8<\/a><\/li>\n\n\n\n<li>Petersen RC. &#8220;Mild Cognitive Impairment as a Diagnostic Entity.&#8221; <em>Journal of Internal Medicine<\/em>, 256(3):183\u2013194, 2004. <a href=\"https:\/\/doi.org\/10.1111\/j.1365-2796.2004.01388.x\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1111\/j.1365-2796.2004.01388.x<\/a><\/li>\n\n\n\n<li>Kwon HS, Koh SH. &#8220;Neuroinflammation in neurodegenerative disorders: the roles of microglia and astrocytes.&#8221; <em>Translational Neurodegeneration<\/em>, 9:42, 2020. <a href=\"https:\/\/doi.org\/10.1186\/s40035-020-00221-2\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1186\/s40035-020-00221-2<\/a><\/li>\n\n\n\n<li>Yoo KY, Kim JH, Kim W. &#8220;Mesenchymal Stem Cells as a Potential Therapeutic Tool for Alzheimer&#8217;s Disease and Mild Cognitive Impairment.&#8221; <em>Neural Plasticity<\/em>, 2021:6627740, 2021. <a href=\"https:\/\/doi.org\/10.1155\/2021\/6627740\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1155\/2021\/6627740<\/a><\/li>\n\n\n\n<li>Kwon MK, et al. &#8220;Intravenous infusion of human umbilical cord blood-derived mesenchymal stem cells in Alzheimer&#8217;s disease: a randomized, double-blind, controlled phase I\/IIa trial.&#8221; <em>Alzheimer&#8217;s Research &amp; Therapy<\/em>, 13:154, 2021. <a href=\"https:\/\/doi.org\/10.1186\/s13195-021-00892-7\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1186\/s13195-021-00892-7<\/a><\/li>\n\n\n\n<li>Oh SH, et al. &#8220;Repeated Intraventricular Infusions of Neural Stem Cells for the Treatment of Alzheimer&#8217;s Disease.&#8221; <em>Journal of Alzheimer&#8217;s Disease<\/em>, 45(4):1021\u20131034, 2015. <a href=\"https:\/\/doi.org\/10.3233\/JAD-142994\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.3233\/JAD-142994<\/a><\/li>\n\n\n\n<li>Erickson KI, et al. &#8220;Exercise training increases size of hippocampus and improves memory.&#8221; <em>Proceedings of the National Academy of Sciences<\/em>, 108(7):3017\u20133022, 2011. <a href=\"https:\/\/doi.org\/10.1073\/pnas.1015950108\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1073\/pnas.1015950108<\/a><\/li>\n\n\n\n<li>Bergmann O, et al. &#8220;Evidence for cardiomyocyte renewal in humans.&#8221; <em>Science<\/em>, 324(5923):98\u2013102, 2009. <a href=\"https:\/\/doi.org\/10.1126\/science.1164680\" target=\"_blank\" rel=\"noopener\" title=\"\">https:\/\/doi.org\/10.1126\/science.1164680<\/a><\/li>\n<\/ol>\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\t\t<div data-elementor-type=\"section\" data-elementor-id=\"21873\" class=\"elementor elementor-21873\" data-elementor-post-type=\"elementor_library\">\n\t\t\t        <section class=\"elementor-section elementor-top-section elementor-element elementor-element-a6ebaad elementor-section-boxed elementor-section-height-default elementor-section-height-default pxl-row-scroll-none pxl-zoom-point-false pxl-section-overflow-visible pxl-section-fix-none pxl-bg-color-none pxl-section-overlay-none\" data-id=\"a6ebaad\" data-element_type=\"section\" data-e-type=\"section\">\n\n                \n                <div 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